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Volumn 45, Issue 1, 2012, Pages 186-199

Melatonin as a neuroprotective agent in the rodent models of Parkinson's disease: Is it all set to irrefutable clinical translation?

Author keywords

Melatonin; Neuroprotection; Parkinson's disease; Rodent models

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALPHA SYNUCLEIN; DOPAMINE; MANEB; MELATONIN; METHAMPHETAMINE; OXIDOPAMINE; PARAQUAT; ROTENONE; UBIQUITIN;

EID: 84856721686     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-011-8225-x     Document Type: Review
Times cited : (64)

References (131)
  • 1
    • 33749184503 scopus 로고    scopus 로고
    • Contribution of genomics and proteomics in understanding the role of modifying factors in Parkinson's disease
    • MP Singh S Patel M Dikshit YK Gupta 2006 Contribution of genomics and proteomics in understanding the role of modifying factors in Parkinson's disease Indian J Biochem Biophys 43 69 81 16955754 1:CAS:528:DC%2BD28XmtFSltb0%3D (Pubitemid 44475398)
    • (2006) Indian Journal of Biochemistry and Biophysics , vol.43 , Issue.2 , pp. 69-81
    • Singh, M.P.1    Patel, S.2    Dikshit, M.3    Gupta, Y.K.4
  • 2
    • 77951648520 scopus 로고    scopus 로고
    • Proteomics in Parkinson's disease: Current trends, translational snags and future possibilities
    • 20121482 1:CAS:528:DC%2BC3cXhtlOitbw%3D
    • G Srivastava K Singh MN Tiwari MP Singh 2010 Proteomics in Parkinson's disease: current trends, translational snags and future possibilities Expert Rev Proteomics 7 127 139 20121482 1:CAS:528:DC%2BC3cXhtlOitbw%3D
    • (2010) Expert Rev Proteomics , vol.7 , pp. 127-139
    • Srivastava, G.1    Singh, K.2    Tiwari, M.N.3    Singh, M.P.4
  • 3
    • 0036010592 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease
    • DOI 10.1002/bies.10067
    • R Betarbet TB Sherer JT Greenamyre 2002 Animal models of Parkinson's disease Bioessays 24 308 318 11948617 1:CAS:528:DC%2BD38XjsFWjtrc%3D (Pubitemid 34305686)
    • (2002) BioEssays , vol.24 , Issue.4 , pp. 308-318
    • Betarbet, R.1    Sherer, T.B.2    Timothy Greenamyre, J.3
  • 4
    • 78549282095 scopus 로고    scopus 로고
    • Antiinflammatory activity of melatonin in central nervous system
    • 21358973 1:CAS:528:DC%2BC3cXhtl2mtrvL
    • E Esposito S Cuzzocrea 2010 Antiinflammatory activity of melatonin in central nervous system Curr Neuropharmacol 8 228 242 21358973 1:CAS:528:DC%2BC3cXhtl2mtrvL
    • (2010) Curr Neuropharmacol , vol.8 , pp. 228-242
    • Esposito, E.1    Cuzzocrea, S.2
  • 5
    • 79960380554 scopus 로고    scopus 로고
    • Melatonin as a natural ally against oxidative stress: A physicochemical examination
    • 21752095 1:CAS:528:DC%2BC3MXpslKqsro%3D
    • A Galano DX Tan RJ Reiter 2011 Melatonin as a natural ally against oxidative stress: a physicochemical examination J Pineal Res 51 1 16 21752095 1:CAS:528:DC%2BC3MXpslKqsro%3D
    • (2011) J Pineal Res , vol.51 , pp. 1-16
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 8
    • 79951634450 scopus 로고    scopus 로고
    • Melatonin or silymarin reduces maneb- and paraquat-induced Parkinson's disease phenotype in the mouse
    • 20964710 1:CAS:528:DC%2BC3MXivF2ksr0%3D
    • NK Singhal G Srivastava DK Patel SK Jain MP Singh 2011 Melatonin or silymarin reduces maneb- and paraquat-induced Parkinson's disease phenotype in the mouse J Pineal Res 50 97 109 20964710 1:CAS:528:DC%2BC3MXivF2ksr0%3D
    • (2011) J Pineal Res , vol.50 , pp. 97-109
    • Singhal, N.K.1    Srivastava, G.2    Patel, D.K.3    Jain, S.K.4    Singh, M.P.5
  • 12
    • 0141702110 scopus 로고    scopus 로고
    • Neuroprotective role of melatonin in oxidative stress vulnerable brain
    • YK Gupta M Gupta K Kohli 2003 Neuroprotective role of melatonin in oxidative stress vulnerable brain Indian J Physiol Pharmacol 47 373 386 15266948 1:CAS:528:DC%2BD3sXotl2jtLk%3D (Pubitemid 37151175)
    • (2003) Indian Journal of Physiology and Pharmacology , vol.47 , Issue.4 , pp. 373-386
    • Gupta, Y.K.1    Gupta, M.2    Kohli, K.3
  • 14
    • 70350075810 scopus 로고    scopus 로고
    • Melatonin inhibits 6-hydroxydopamine production in the brain to protect against experimental Parkinsonism in rodents
    • 19796048 1:CAS:528:DC%2BD1MXhtlOqtLjF
    • A Borah KP Mohanakumar 2009 Melatonin inhibits 6-hydroxydopamine production in the brain to protect against experimental Parkinsonism in rodents J Pineal Res 47 293 300 19796048 1:CAS:528:DC%2BD1MXhtlOqtLjF
    • (2009) J Pineal Res , vol.47 , pp. 293-300
    • Borah, A.1    Mohanakumar, K.P.2
  • 15
    • 43049165779 scopus 로고    scopus 로고
    • Melatonin inhibits amphetamine-induced increase in alpha-synuclein and decrease in phosphorylated tyrosine hydroxylase in SK-N-SH cells
    • 18406059 1:CAS:528:DC%2BD1cXls1Shtb0%3D
    • S Klongpanichapak P Phansuwan-Pujito M Ebadi P Govitrapong 2008 Melatonin inhibits amphetamine-induced increase in alpha-synuclein and decrease in phosphorylated tyrosine hydroxylase in SK-N-SH cells Neurosci Lett 436 309 313 18406059 1:CAS:528:DC%2BD1cXls1Shtb0%3D
    • (2008) Neurosci Lett , vol.436 , pp. 309-313
    • Klongpanichapak, S.1    Phansuwan-Pujito, P.2    Ebadi, M.3    Govitrapong, P.4
  • 17
    • 68249127673 scopus 로고    scopus 로고
    • Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice
    • 19437546 1:CAS:528:DC%2BD1MXhtVSntbrP
    • V Tapias G Escames LC López A Lopez E Camacho MD Carrión A Entrena MA Gallo A Espinosa D Acuña-Castroviejo 2009 Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice J Neurosci Res 87 3002 3010 19437546 1:CAS:528:DC%2BD1MXhtVSntbrP
    • (2009) J Neurosci Res , vol.87 , pp. 3002-3010
    • Tapias, V.1    Escames, G.2    López, L.C.3    Lopez, A.4    Camacho, E.5    Carrión, M.D.6    Entrena, A.7    Gallo, M.A.8    Espinosa, A.9    Acuña-Castroviejo, D.10
  • 18
    • 79952555798 scopus 로고    scopus 로고
    • Melatonin has membrane receptor-independent hypnotic action on neurons: An hypothesis
    • 21210841 1:CAS:528:DC%2BC3MXjs1Gltrw%3D
    • JE Jan RJ Reiter PK Wong MC Bax U Ribary MB Wasdell 2011 Melatonin has membrane receptor-independent hypnotic action on neurons: an hypothesis J Pineal Res 50 233 240 21210841 1:CAS:528:DC%2BC3MXjs1Gltrw%3D
    • (2011) J Pineal Res , vol.50 , pp. 233-240
    • Jan, J.E.1    Reiter, R.J.2    Wong, P.K.3    Bax, M.C.4    Ribary, U.5    Wasdell, M.B.6
  • 19
    • 79951606158 scopus 로고    scopus 로고
    • Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: A possible role in neuroprotection
    • 21073519 1:CAS:528:DC%2BC3MXivF2ksro%3D
    • KJ Kwon JN Kim MK Kim J Lee LJ Ignarro HJ Kim CY Shin SH Han 2011 Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: a possible role in neuroprotection J Pineal Res 50 110 123 21073519 1:CAS:528:DC%2BC3MXivF2ksro%3D
    • (2011) J Pineal Res , vol.50 , pp. 110-123
    • Kwon, K.J.1    Kim, J.N.2    Kim, M.K.3    Lee, J.4    Ignarro, L.J.5    Kim, H.J.6    Shin, C.Y.7    Han, S.H.8
  • 20
    • 0342275227 scopus 로고    scopus 로고
    • Melatonin levels in Parkinson's disease: Drug therapy versus electrical stimulation of the internal globus pallidus
    • DOI 10.1016/S0531-5565(96)00173-8, PII S0531556596001738
    • MD Catala C Canete-Nicolas A Iradi PJ Tarazona JM Tormos A Pascual-Leone 1997 Melatonin levels in Parkinson's disease: drug therapy versus electrical stimulation of the internal globus pallidus Exp Gerontol 32 553 558 9315456 1:CAS:528:DyaK2sXmtVGhtr0%3D (Pubitemid 27366490)
    • (1997) Experimental Gerontology , vol.32 , Issue.4-5 , pp. 553-558
    • Catala, M.D.1    Canete-Nicolas, C.2    Iradi, A.3    Tarazona, F.J.4    Tormos, J.M.5    Pascual-Leone, A.6
  • 21
    • 34249072817 scopus 로고    scopus 로고
    • Effect of exogenous melatonin on sleep and motor dysfunction in Parkinson's disease: A randomized, double blind, placebo-controlled study
    • DOI 10.1007/s00415-006-0390-x
    • CA Medeiros PF Carvalhedo de Bruin LA Lopes MC Magalhaes SM de Lourdes VM de Bruin 2007 Effect of exogenous melatonin on sleep and motor dysfunction in Parkinson's disease. A randomized, double blind, placebo-controlled study J Neurol 254 459 464 17404779 1:CAS:528:DC%2BD2sXlvF2isrw%3D (Pubitemid 46786720)
    • (2007) Journal of Neurology , vol.254 , Issue.4 , pp. 459-464
    • Medeiros, C.A.M.1    Carvalhedo De Bruin, P.F.2    Lopes, L.A.3    Magalhaes, M.C.4    De Lourdes Seabra, M.5    Sales De Bruin, V.M.6
  • 22
    • 0036778511 scopus 로고    scopus 로고
    • Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype
    • DOI 10.1016/S0161-813X(02)00092-X, PII S0161813X0200092X
    • M Thiruchelvam EK Richfield BM Goodman RB Baggs DA Cory-Slechta 2002 Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype Neurotoxicology 23 621 633 12428734 1:CAS:528: DC%2BD38XnvVGrtbg%3D (Pubitemid 36527682)
    • (2002) NeuroToxicology , vol.23 , Issue.4-5 , pp. 621-633
    • Thiruchelvam, M.1    Richfield, E.K.2    Goodman, B.M.3    Baggs, R.B.4    Cory-Slechta, D.A.5
  • 23
    • 26844505808 scopus 로고    scopus 로고
    • Toxin-induced models of Parkinson's disease
    • DOI 10.1602/neurorx.2.3.484
    • J Bove D Prou C Perier S Przedborski 2005 Toxin-induced models of Parkinson's disease NeuroRx 2 484 494 16389312 (Pubitemid 41444882)
    • (2005) NeuroRx , vol.2 , Issue.3 , pp. 484-494
    • Bove, J.1    Prou, D.2    Perier, C.3    Przedborski, S.4
  • 24
    • 27344438938 scopus 로고    scopus 로고
    • Microglial inflammation in the parkinsonian substantia nigra: Relationship to alpha-synuclein deposition
    • 15935098
    • E Croisier LB Moran DT Dexter RK Pearce MB Graeber 2005 Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition J Neuroinflammation 2 14 15935098
    • (2005) J Neuroinflammation , vol.2 , pp. 14
    • Croisier, E.1    Moran, L.B.2    Dexter, D.T.3    Pearce, R.K.4    Graeber, M.B.5
  • 26
    • 5544229693 scopus 로고    scopus 로고
    • Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP
    • DOI 10.1007/s00441-004-0938-y
    • A Schober 2004 Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP Cell Tissue Res 318 215 224 15503155 (Pubitemid 39366054)
    • (2004) Cell and Tissue Research , vol.318 , Issue.1 , pp. 215-224
    • Schober, A.1
  • 27
    • 5444255433 scopus 로고    scopus 로고
    • Neurotoxicant-induced animal models of Parkinson's disease: Understanding the role of rotenone, maneb and paraquat in neurodegeneration
    • DOI 10.1007/s00441-004-0937-z
    • VN Uversky 2004 Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration Cell Tissue Res 318 225 241 15258850 1:CAS:528: DC%2BD2cXos1aqsLk%3D (Pubitemid 39362642)
    • (2004) Cell and Tissue Research , vol.318 , Issue.1 , pp. 225-241
    • Uversky, V.N.1
  • 28
    • 0033550706 scopus 로고    scopus 로고
    • Ultrastructural confirmation of neuronal protection by melatonin against the neurotoxin 6-hydroxydopamine cell damage
    • DOI 10.1016/S0006-8993(98)01262-1, PII S0006899398012621
    • JC Mayo RM Sainz I Antolín C Rodriguez 1999 Ultrastructural confirmation of neuronal protection by melatonin against the neurotoxin 6-hydroxydopamine cell damage Brain Res 818 221 227 10082807 1:CAS:528:DyaK1MXnslOqsg%3D%3D (Pubitemid 29229935)
    • (1999) Brain Research , vol.818 , Issue.2 , pp. 221-227
    • Mayo, J.C.1    Sainz, R.M.2    Antolin, I.3    Rodriguez, C.4
  • 29
    • 0032514249 scopus 로고    scopus 로고
    • Melatonin protects 6-OHDA-induced neuronal death of nigrostriatal dopaminergic system
    • YS Kim WS Joo BK Jin YH Cho HH Baik CW Park 1998 Melatonin protects 6-OHDA-induced neuronal death of nigrostriatal dopaminergic system Neuroreport 9 2387 2390 9694233 1:CAS:528:DyaK1cXltVKltL4%3D (Pubitemid 28338239)
    • (1998) NeuroReport , vol.9 , Issue.10 , pp. 2387-2390
    • Kim, Y.S.1    Joo, W.S.2    Jin, B.K.3    Cho, Y.H.4    Baik, H.H.5    Park, C.W.6
  • 30
    • 0032556763 scopus 로고    scopus 로고
    • Melatonin increases striatal dopaminergic function in 6-OHDA-lesioned rats
    • WS Joo BK Jin CW Park SH Maeng YS Kim 1998 Melatonin increases striatal dopaminergic function in 6-OHDA-lesioned rats Neuroreport 9 4123 4126 9926859 1:CAS:528:DyaK1MXpvFSktg%3D%3D (Pubitemid 29030700)
    • (1998) NeuroReport , vol.9 , Issue.18 , pp. 4123-4126
    • Joo, W.S.1    Jin, B.K.2    Park, C.W.3    Maeng, S.H.4    Kim, Y.S.5
  • 31
    • 0035170284 scopus 로고    scopus 로고
    • Melatonin protects against 6-OHDA-induced neurotoxicity in rats: A role for mitochondrial complex I activity
    • DOI 10.1096/fj.00-0129com
    • F Dabbeni-Sala S Di Santo D Franceschini SD Skaper P Giusti 2001 Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity FASEB J 15 164 170 11149904 1:CAS:528:DC%2BD3MXht1Snsb4%3D (Pubitemid 32061667)
    • (2001) FASEB Journal , vol.15 , Issue.1 , pp. 164-170
    • Dabbeni-Sala, F.1    Di Santo, S.2    Franceschini, D.3    Skaper, S.D.4    Giusti, P.5
  • 32
    • 0037126922 scopus 로고    scopus 로고
    • Melatonin reverses neurochemical alterations induced by 6-OHDA in rat striatum
    • DOI 10.1016/S0024-3205(01)01480-1, PII S0024320501014801
    • LM Aguiar SM Vasconcelos FC Sousa GS Viana 2002 Melatonin reverses neurochemical alterations induced by 6-OHDA in rat striatum Life Sci 70 1041 1051 11862988 1:CAS:528:DC%2BD38XovVWitA%3D%3D (Pubitemid 34086948)
    • (2002) Life Sciences , vol.70 , Issue.9 , pp. 1041-1051
    • Aguiar, L.M.V.1    Vasconcelos, S.M.M.2    Sousa, F.C.F.3    Viana, G.S.B.4
  • 33
    • 0031981649 scopus 로고    scopus 로고
    • Melatonin prevents apoptosis induced by 6-hydroxydopamine in neuronal cells: Implications for Parkinson's disease
    • DOI 10.1111/j.1600-079X.1998.tb00531.x
    • JC Mayo RM Sainz H Uria I Antolin MM Esteban C Rodriguez 1998 Melatonin prevents apoptosis induced by 6-hydroxydopamine in neuronal cells: implications for Parkinson's disease J Pineal Res 24 179 192 9551855 1:CAS:528: DyaK1cXhvFSisr0%3D (Pubitemid 28156603)
    • (1998) Journal of Pineal Research , vol.24 , Issue.3 , pp. 179-192
    • Mayo, J.C.1    Sainz, R.M.2    Uria, H.3    Antolin, I.4    Esteban, M.M.5    Rodriguez, C.6
  • 34
    • 0032973751 scopus 로고    scopus 로고
    • A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease
    • DOI 10.1016/S0031-9384(99)00023-2, PII S0031938499000232
    • GL Willis SM Armstrong 1999 A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease Physiol Behav 66 785 795 10405106 1:CAS:528:DyaK1MXktlGju7k%3D (Pubitemid 29281640)
    • (1999) Physiology and Behavior , vol.66 , Issue.5 , pp. 785-795
    • Willis, G.L.1    Armstrong, S.M.2
  • 35
    • 34247204351 scopus 로고    scopus 로고
    • Neuroprotection of the nigrostriatal dopaminergic neurons by melatonin in hemiparkinsonium rat
    • S Singh R Ahmed RK Sagar B Krishana 2006 Neuroprotection of the nigrostriatal dopaminergic neurons by melatonin in hemiparkinsonium rat Indian J Med Res 124 419 426 17159262 1:CAS:528:DC%2BD2sXht1als7c%3D (Pubitemid 46603377)
    • (2006) Indian Journal of Medical Research , vol.124 , Issue.OCT. , pp. 419-426
    • Singh, S.1    Ahmed, R.2    Sagar, R.K.3    Krishana, B.4
  • 36
    • 58149466868 scopus 로고    scopus 로고
    • Oxidative and inflammatory pathways in Parkinson's disease
    • 18363100 1:CAS:528:DC%2BD1MXktVejtw%3D%3D
    • RL Miller M James-Kracke GY Sun AY Sun 2009 Oxidative and inflammatory pathways in Parkinson's disease Neurochem Res 34 55 65 18363100 1:CAS:528:DC%2BD1MXktVejtw%3D%3D
    • (2009) Neurochem Res , vol.34 , pp. 55-65
    • Miller, R.L.1    James-Kracke, M.2    Sun, G.Y.3    Sun, A.Y.4
  • 37
    • 0020680904 scopus 로고
    • Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
    • JW Langston P Ballard JW Tetrud I Irwin 1983 Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis Science 219 979 980 6823561 1:STN:280:DyaL3s7hvF2mtg%3D%3D (Pubitemid 13189531)
    • (1983) Science , vol.219 , Issue.4587 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3    Irwin, I.4
  • 38
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
    • DOI 10.1002/1531-8249(199910)46:4<598::AID-ANA7>3.0.CO;2-F
    • JW Langston LS Forno J Tetrud AG Reeves JA Kaplan D Karluk 1999 Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure Ann Neurol 46 598 605 10514096 1:CAS:528:DyaK1MXmvVGitbg%3D (Pubitemid 29466438)
    • (1999) Annals of Neurology , vol.46 , Issue.4 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3    Reeves, A.G.4    Kaplan, J.A.5    Karluk, D.6
  • 39
    • 84863116750 scopus 로고    scopus 로고
    • Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease
    • 12897068 1:CAS:528:DC%2BD3sXot1KitL8%3D
    • HM Gao B Liu W Zhang JS Hong 2003 Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease FASEB J 17 1954 1956 12897068 1:CAS:528:DC%2BD3sXot1KitL8%3D
    • (2003) FASEB J , vol.17 , pp. 1954-1956
    • Gao, H.M.1    Liu, B.2    Zhang, W.3    Hong, J.S.4
  • 40
    • 0344824689 scopus 로고    scopus 로고
    • + analogs acting on mitochondria and inducing neuro-degeneration
    • DOI 10.2174/0929867033456558
    • Y Kotake S Ohta 2003 MPP+ analogs acting on mitochondria and inducing neuro-degeneration Curr Med Chem 10 2507 2516 14529466 1:CAS:528: DC%2BD3sXpt1Kmsb0%3D (Pubitemid 37456021)
    • (2003) Current Medicinal Chemistry , vol.10 , Issue.23 , pp. 2507-2516
    • Kotake, Y.1    Ohta, S.2
  • 41
    • 0033948968 scopus 로고    scopus 로고
    • Protective effect of melatonin against the 1-methyl-4-phenylpyridinium- induced inhibition of Complex I of the mitochondrial respiratory chain
    • E Absi A Ayala A Machado J Parrado 2000 Protective effect of melatonin against the 1-methyl-4-phenylpyridinium-induced inhibition of complex I of the mitochondrial respiratory chain J Pineal Res 29 40 47 10949539 1:CAS:528:DC%2BD3cXltl2ht70%3D (Pubitemid 30449700)
    • (2000) Journal of Pineal Research , vol.29 , Issue.1 , pp. 40-47
    • Absi, E.1    Ayala, A.2    Machado, A.3    Parrado, J.4
  • 43
    • 0031845040 scopus 로고    scopus 로고
    • Oxidative damage in the central nervous system: Protection by melatonin
    • DOI 10.1016/S0301-0082(98)00052-5, PII S0301008298000525
    • RJ Reiter 1998 Oxidative damage in the central nervous system: protection by melatonin Prog Neurobiol 56 359 384 9770244 1:CAS:528:DyaK1cXmtFKhtbc%3D (Pubitemid 28389724)
    • (1998) Progress in Neurobiology , vol.56 , Issue.3 , pp. 359-384
    • Reiter, R.J.1
  • 44
    • 0030606143 scopus 로고    scopus 로고
    • Melatonin is protective against MPTP-induced striatal and hippocampal lesions
    • 9000122 1:CAS:528:DyaK28XnsFSgsb4%3D
    • D Acuna-Castroviejo A Coto-Montes M Gaia Monti GG Ortiz RJ Reiter 1997 Melatonin is protective against MPTP-induced striatal and hippocampal lesions Life Sci 60 PL23 PL29 9000122 1:CAS:528:DyaK28XnsFSgsb4%3D
    • (1997) Life Sci , vol.60
    • Acuna-Castroviejo, D.1    Coto-Montes, A.2    Gaia Monti, M.3    Ortiz, G.G.4    Reiter, R.J.5
  • 45
    • 50549091192 scopus 로고    scopus 로고
    • Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats
    • 18674531 1:CAS:528:DC%2BD1cXhtVynurzK
    • C Capitelli A Sereniki MM Lima AB Reksidler S Tufik MA Vital 2008 Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats Eur J Pharmacol 594 101 108 18674531 1:CAS:528: DC%2BD1cXhtVynurzK
    • (2008) Eur J Pharmacol , vol.594 , pp. 101-108
    • Capitelli, C.1    Sereniki, A.2    Lima, M.M.3    Reksidler, A.B.4    Tufik, S.5    Vital, M.A.6
  • 46
    • 0037067791 scopus 로고    scopus 로고
    • Protective effect of melatonin in a chronic experimental model of Parkinson's disease
    • DOI 10.1016/S0006-8993(02)02551-9, PII S0006899302025519
    • I Antolín JC Mayo RM Sainz ML del Brío F Herrera V Martín C Rodríguez 2002 Protective effect of melatonin in a chronic experimental model of Parkinson's disease Brain Res 943 163 173 12101038 (Pubitemid 36120376)
    • (2002) Brain Research , vol.943 , Issue.2 , pp. 163-173
    • Antolin, I.1    Mayo, J.C.2    Sainz, R.M.3    Del Brio, M.D.L.A.4    Herrera, F.5    Martin, V.6    Rodriguez, C.7
  • 47
    • 64249129142 scopus 로고    scopus 로고
    • Does melatonin help save dopaminergic cells in MPTP-treated mice?
    • 18793863
    • J Ma VE Shaw J Mitrofanis 2009 Does melatonin help save dopaminergic cells in MPTP-treated mice? Parkinsonism Relat Disord 15 307 314 18793863
    • (2009) Parkinsonism Relat Disord , vol.15 , pp. 307-314
    • Ma, J.1    Shaw, V.E.2    Mitrofanis, J.3
  • 48
    • 77957943337 scopus 로고    scopus 로고
    • The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6
    • 20815783 1:CAS:528:DC%2BC3cXht1yjsrrF
    • R Niranjan C Nath R Shukla 2010 The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6 Free Radic Res 44 1304 1316 20815783 1:CAS:528:DC%2BC3cXht1yjsrrF
    • (2010) Free Radic Res , vol.44 , pp. 1304-1316
    • Niranjan, R.1    Nath, C.2    Shukla, R.3
  • 49
    • 0036161352 scopus 로고    scopus 로고
    • Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical
    • DOI 10.1034/j.1600-079x.2002.10831.x
    • XJ Li J Gu SD Lu FY Sun 2002 Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical J Pineal Res 32 47 52 11841600 (Pubitemid 34123756)
    • (2002) Journal of Pineal Research , vol.32 , Issue.1 , pp. 47-52
    • Li, X.-J.1    Gu, J.2    Lu, S.-D.3    Sun, F.-Y.4
  • 50
    • 77955516215 scopus 로고    scopus 로고
    • Fibroblast growth factor 9 upregulates heme oxygenase-1 and gamma-glutamylcysteine synthetase expression to protect neurons from 1-methyl-4-phenylpyridinium toxicity
    • 20615462 1:CAS:528:DC%2BC3cXhtVeksrjK
    • JY Huang JI Chuang 2010 Fibroblast growth factor 9 upregulates heme oxygenase-1 and gamma-glutamylcysteine synthetase expression to protect neurons from 1-methyl-4-phenylpyridinium toxicity Free Radic Biol Med 49 1099 1108 20615462 1:CAS:528:DC%2BC3cXhtVeksrjK
    • (2010) Free Radic Biol Med , vol.49 , pp. 1099-1108
    • Huang, J.Y.1    Chuang, J.I.2
  • 51
    • 1342280378 scopus 로고    scopus 로고
    • Effect of melatonin on temporal changes of reactive oxygen species and glutathione after MPP(+) treatment in human astrocytoma U373MG cells
    • 14962063 1:CAS:528:DC%2BD2cXhs1Sru7k%3D
    • JI Chuang TH Chen 2004 Effect of melatonin on temporal changes of reactive oxygen species and glutathione after MPP(+) treatment in human astrocytoma U373MG cells J Pineal Res 36 117 125 14962063 1:CAS:528: DC%2BD2cXhs1Sru7k%3D
    • (2004) J Pineal Res , vol.36 , pp. 117-125
    • Chuang, J.I.1    Chen, T.H.2
  • 52
    • 1642440103 scopus 로고    scopus 로고
    • Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine in the mouse nigrostriatum
    • DOI 10.1046/j.1600-079X.2003.00096.x
    • B Thomas KP Mohanakumar 2004 Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the mouse nigrostriatum J Pineal Res 36 25 32 14675127 1:CAS:528:DC%2BD2cXotFKksg%3D%3D (Pubitemid 38130286)
    • (2004) Journal of Pineal Research , vol.36 , Issue.1 , pp. 25-32
    • Thomas, B.1    Mohanakumar, K.P.2
  • 53
    • 0036255661 scopus 로고    scopus 로고
    • Melatonin attenuates MPP+-induced neurodegeneration and glutathione impairment in the nigrostriatal dopaminergic pathway
    • 11982797 1:CAS:528:DC%2BD38XktlWjtL4%3D
    • ST Chen JI Chuang MH Hong EI Li 2002 Melatonin attenuates MPP+-induced neurodegeneration and glutathione impairment in the nigrostriatal dopaminergic pathway J Pineal Res 32 262 269 11982797 1:CAS:528:DC%2BD38XktlWjtL4%3D
    • (2002) J Pineal Res , vol.32 , pp. 262-269
    • Chen, S.T.1    Chuang, J.I.2    Hong, M.H.3    Li, E.I.4
  • 55
    • 34447577880 scopus 로고    scopus 로고
    • +-induced caspase-mediated death pathway and DNA fragmentation factor-45 cleavage in SK-N-SH cultured cells
    • DOI 10.1111/j.1600-079X.2007.00449.x
    • J Chetsawang P Govitrapong B Chetsawang 2007 Melatonin inhibits MPP+-induced caspase-mediated death pathway and DNA fragmentation factor-45 cleavage in SK-N-SH cultured cells J Pineal Res 43 115 120 17645689 1:CAS:528:DC%2BD2sXovFant7o%3D (Pubitemid 47077216)
    • (2007) Journal of Pineal Research , vol.43 , Issue.2 , pp. 115-120
    • Chetsawang, J.1    Govitrapong, P.2    Chetsawang, B.3
  • 56
    • 0030843476 scopus 로고    scopus 로고
    • Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress
    • DOI 10.1016/S0006-8993(97)00668-9, PII S0006899397006689
    • L Iacovitti ND Stull K Johnston 1997 Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress Brain Res 768 317 326 9369331 1:CAS:528:DyaK2sXlslelt7k%3D (Pubitemid 27433507)
    • (1997) Brain Research , vol.768 , Issue.1-2 , pp. 317-326
    • Iacovitti, L.1    Stull, N.D.2    Johnston, K.3
  • 57
    • 0000785747 scopus 로고    scopus 로고
    • Melatonin fails to protect against long-term MPTP-induced dopamine depletion in mouse striatum
    • 12835094
    • CJ Van der Schyf K Castagnoli S Palmer L Hazelwood N Castagnoli Jr 2000 Melatonin fails to protect against long-term MPTP-induced dopamine depletion in mouse striatum Neurotox Res 1 261 269 12835094
    • (2000) Neurotox Res , vol.1 , pp. 261-269
    • Van Der Schyf, C.J.1    Castagnoli, K.2    Palmer, S.3    Hazelwood, L.4    Castagnoli Jr., N.5
  • 58
    • 0037669427 scopus 로고    scopus 로고
    • Circadian rhythms of oxidative phosphorylation: Effects of rotenone and melatonin on isolated rat brain mitochondria
    • DOI 10.1081/CBI-120021385
    • N Simon K Papa J Vidal A Boulamery B Bruguerolle 2003 Circadian rhythms of oxidative phosphorylation: effects of rotenone and melatonin on isolated rat brain mitochondria Chronobiol Int 20 451 461 12868540 1:CAS:528: DC%2BD3sXmtFGgurg%3D (Pubitemid 36828478)
    • (2003) Chronobiology International , vol.20 , Issue.3 , pp. 451-461
    • Simon, N.1    Papa, K.2    Vidal, J.3    Boulamery, A.4    Bruguerolle, B.5
  • 59
    • 0036075892 scopus 로고    scopus 로고
    • Environmental risk factors and Parkinson's disease: Selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
    • 12127150 1:CAS:528:DC%2BD38XltFyrtbs%3D
    • AL McCormack M Thiruchelvam AB Manning-Bog C Thiffault JW Langston DA Cory-Slechta DA Di Monte 2002 Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat Neurobiol Dis 10 119 217 12127150 1:CAS:528: DC%2BD38XltFyrtbs%3D
    • (2002) Neurobiol Dis , vol.10 , pp. 119-217
    • McCormack, A.L.1    Thiruchelvam, M.2    Manning-Bog, A.B.3    Thiffault, C.4    Langston, J.W.5    Cory-Slechta, D.A.6    Di Monte, D.A.7
  • 60
    • 33645739484 scopus 로고    scopus 로고
    • Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: Mechanism of neurodegeneration
    • 16510128 1:CAS:528:DC%2BD28XjsFOnurs%3D
    • S Patel V Singh A Kumar YK Gupta MP Singh 2006 Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration Brain Res 1081 9 18 16510128 1:CAS:528:DC%2BD28XjsFOnurs%3D
    • (2006) Brain Res , vol.1081 , pp. 9-18
    • Patel, S.1    Singh, V.2    Kumar, A.3    Gupta, Y.K.4    Singh, M.P.5
  • 61
    • 35348935580 scopus 로고    scopus 로고
    • Identification of differentially expressed proteins in striatum of maneb-and paraquat-induced Parkinson's disease phenotype in mouse
    • DOI 10.1016/j.ntt.2007.04.002, PII S089203620700270X
    • S Patel A Sinha MP Singh 2007 Identification of differentially expressed proteins in striatum of maneb-and paraquat-induced Parkinson's disease phenotype in mouse Neurotoxicol Teratol 29 578 585 17532186 1:CAS:528:DC%2BD2sXht1aksLbI (Pubitemid 47599875)
    • (2007) Neurotoxicology and Teratology , vol.29 , Issue.5 , pp. 578-585
    • Patel, S.1    Sinha, A.2    Singh, M.P.3
  • 62
    • 55949131727 scopus 로고    scopus 로고
    • Gene expression profiles of mouse striatum in control and maneb + paraquat-induced Parkinson's disease phenotype: Validation of differentially expressed energy metabolizing transcripts
    • 18386188 1:CAS:528:DC%2BD1cXhtVKntb%2FM
    • S Patel K Singh S Singh MP Singh 2008 Gene expression profiles of mouse striatum in control and maneb + paraquat-induced Parkinson's disease phenotype: validation of differentially expressed energy metabolizing transcripts Mol Biotechnol 40 59 68 18386188 1:CAS:528:DC%2BD1cXhtVKntb%2FM
    • (2008) Mol Biotechnol , vol.40 , pp. 59-68
    • Patel, S.1    Singh, K.2    Singh, S.3    Singh, M.P.4
  • 63
    • 23844483173 scopus 로고    scopus 로고
    • Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial Nigra: Implications for Parkinson disease
    • DOI 10.1074/jbc.M500984200
    • J Peng FF Stevenson SR Doctrow JK Andersen 2005 Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease J Biol Chem 80 29194 29198 (Pubitemid 41161371)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.32 , pp. 29194-29198
    • Peng, J.1    Stevenson, F.F.2    Doctrow, S.R.3    Andersen, J.K.4
  • 64
    • 0037490957 scopus 로고    scopus 로고
    • Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture
    • DOI 10.1016/S0168-0102(03)00163-9
    • K Shimizu K Matsubara K Ohtaki H Shiono 2003 Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture Neurosci Res 46 523 532 12871774 1:CAS:528:DC%2BD3sXlsVaitLc%3D (Pubitemid 36842803)
    • (2003) Neuroscience Research , vol.46 , Issue.4 , pp. 523-532
    • Shimizu, K.1    Matsubara, K.2    Ohtaki, K.-I.3    Shiono, H.4
  • 65
    • 0034671469 scopus 로고    scopus 로고
    • The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: Implications for Parkinson's disease
    • M Thiruchelvam EK Richfield RB Baggs AW Tank DA Cory-Slechta 2000 The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease J Neurosci 20 9207 9214 11124998 1:CAS:528:DC%2BD3MXis1Wiuw%3D%3D (Pubitemid 32042923)
    • (2000) Journal of Neuroscience , vol.20 , Issue.24 , pp. 9207-9214
    • Thiruchelvam, M.1    Richfield, E.K.2    Baggs, R.B.3    Tank, A.W.4    Cory-Slechta, D.A.5
  • 66
    • 33845392575 scopus 로고    scopus 로고
    • Paraquat-induced oxidative stress in Drosophila melanogaster: Effects of melatonin, glutathione, serotonin, minocycline, lipoic acid and ascorbic acid
    • DOI 10.1007/s11064-006-9194-8
    • E Bonilla S Medina-Leendertz V Villalobos L Molero A Bohorquez 2006 Paraquat-induced oxidative stress in Drosophila melanogaster: effects of melatonin, glutathione, serotonin, minocycline, lipoic acid and ascorbic acid Neurochem Res 31 1425 1432 17086442 1:CAS:528:DC%2BD28Xht1OhtrfJ (Pubitemid 44900582)
    • (2006) Neurochemical Research , vol.31 , Issue.12 , pp. 1425-1432
    • Bonilla, E.1    Medina-Leendertz, S.2    Villalobos, V.3    Molero, L.4    Bohorquez, A.5
  • 67
    • 23744485610 scopus 로고    scopus 로고
    • Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin
    • DOI 10.1111/j.1600-079X.2005.00234.x
    • DX Tan LC Manchester RM Sainz JC Mayo J Leon R Hardeland B Poeggeler RJ Reiter 2005 Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin J Pineal Res 39 185 194 16098097 1:CAS:528:DC%2BD2MXovFSjtr0%3D (Pubitemid 41140758)
    • (2005) Journal of Pineal Research , vol.39 , Issue.2 , pp. 185-194
    • Tan, D.-X.1    Manchester, L.C.2    Sainz, R.M.3    Mayo, J.C.4    Leon, J.5    Hardeland, R.6    Poeggeler, B.7    Reiter, R.J.8
  • 69
    • 0034754612 scopus 로고    scopus 로고
    • Effects of melatonin on paraquat or ultraviolet light exposure-induced DNA damage
    • DOI 10.1034/j.1600-079X.2001.310404.x
    • HA Yamamoto PV Mohanan 2001 Effects of melatonin on paraquat or ultraviolet light exposure-induced DNA damage J Pineal Res 31 308 313 11703559 1:CAS:528:DC%2BD3MXotlCnt70%3D (Pubitemid 33032945)
    • (2001) Journal of Pineal Research , vol.31 , Issue.4 , pp. 308-313
    • Yamamoto, H.-A.1    Mohanan, P.V.2
  • 70
    • 0029928445 scopus 로고    scopus 로고
    • Paraquat toxicity and oxidative damage. Reduction by melatonin
    • 8866832 1:CAS:528:DyaK28XitVOmt7o%3D
    • D Melchiorri RJ Reiter E Sewerynek M Hara L Chen G Nistico 1996 Paraquat toxicity and oxidative damage. Reduction by melatonin Biochem Pharmacol 51 1095 1099 8866832 1:CAS:528:DyaK28XitVOmt7o%3D
    • (1996) Biochem Pharmacol , vol.51 , pp. 1095-1099
    • Melchiorri, D.1    Reiter, R.J.2    Sewerynek, E.3    Hara, M.4    Chen, L.5    Nistico, G.6
  • 71
    • 33846921608 scopus 로고    scopus 로고
    • Melatonin inhibits maneb-induced aggregation of α-synuclein in rat pheochromocytoma cells
    • DOI 10.1111/j.1600-079X.2006.00390.x
    • M Ishido 2007 Melatonin inhibits maneb-induced aggregation of alpha-synuclein in rat pheochromocytoma cells J Pineal Res 42 125 130 17286743 1:CAS:528:DC%2BD2sXitlygsbo%3D (Pubitemid 46233057)
    • (2007) Journal of Pineal Research , vol.42 , Issue.2 , pp. 125-130
    • Ishido, M.1
  • 72
    • 39149122800 scopus 로고    scopus 로고
    • Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats
    • 18289173 1:CAS:528:DC%2BD1cXjtFCgur0%3D
    • CH Lin JY Huang CH Ching JI Chuang 2008 Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats J Pineal Res 44 205 213 18289173 1:CAS:528:DC%2BD1cXjtFCgur0%3D
    • (2008) J Pineal Res , vol.44 , pp. 205-213
    • Lin, C.H.1    Huang, J.Y.2    Ching, C.H.3    Chuang, J.I.4
  • 73
    • 74049134972 scopus 로고    scopus 로고
    • Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model
    • 19681169 1:CAS:528:DC%2BD1MXhsFensb3K
    • V Tapias JR Cannon JT Greenamyre 2010 Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model J Neurosci Res 88 420 427 19681169 1:CAS:528:DC%2BD1MXhsFensb3K
    • (2010) J Neurosci Res , vol.88 , pp. 420-427
    • Tapias, V.1    Cannon, J.R.2    Greenamyre, J.T.3
  • 74
    • 33847675291 scopus 로고    scopus 로고
    • Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model
    • DOI 10.1111/j.1600-079X.2006.00412.x
    • KS Saravanan KM Sindhu KP Mohanakumar 2007 Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model J Pineal Res 42 247 253 17349022 1:CAS:528:DC%2BD2sXltFCntbc%3D (Pubitemid 46365061)
    • (2007) Journal of Pineal Research , vol.42 , Issue.3 , pp. 247-253
    • Saravanan, K.S.1    Sindhu, K.M.2    Mohanakumar, K.P.3
  • 75
    • 10044292870 scopus 로고    scopus 로고
    • Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster
    • DOI 10.1523/JNEUROSCI.2993-04.2004
    • H Coulom S Birman 2004 Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster J Neurosci 24 10993 10998 15574749 1:CAS:528:DC%2BD2cXhtFShu77F (Pubitemid 39602410)
    • (2004) Journal of Neuroscience , vol.24 , Issue.48 , pp. 10993-10998
    • Coulom, H.1    Birman, S.2
  • 76
    • 24144483470 scopus 로고    scopus 로고
    • 2+-induced mitochondrial oxidative stress and PC12 cell death
    • DOI 10.1089/ars.2005.7.1110
    • SC Sousa RF Castilho 2005 Protective effect of melatonin on rotenone plus Ca2+-induced mitochondrial oxidative stress and PC12 cell death Antioxid Redox Signal 7 1110 1116 16115015 1:CAS:528:DC%2BD2MXos1eqsr4%3D (Pubitemid 41232507)
    • (2005) Antioxidants and Redox Signaling , vol.7 , Issue.9-10 , pp. 1110-1116
    • Sousa, S.C.1    Castilho, R.F.2
  • 77
    • 0029845140 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man
    • DOI 10.1007/BF01291788
    • M Gerlach P Reiderer 1996 Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man J Neural Transm 103 987 1041 9013391 1:CAS:528:DyaK28XntVKku7Y%3D (Pubitemid 26383833)
    • (1996) Journal of Neural Transmission , vol.103 , Issue.8-9 , pp. 987-1041
    • Gerlach, M.1    Riederer, P.2
  • 78
    • 0036289672 scopus 로고    scopus 로고
    • The protective role of L-carnitine against neurotoxicity evoked by drug of abuse, methamphetamine, could be related to mitochondrial dysfunction
    • A Virmani F Gaetani S Imam Z Binienda S Ali 2002 The protective role of L-carnitine against neurotoxicity evoked by drug of abuse, methamphetamine, could be related to mitochondrial dysfunction Ann N Y Acad Sci 965 225 232 12105098 1:CAS:528:DC%2BD38XlvVOjt7s%3D (Pubitemid 34721970)
    • (2002) Annals of the New York Academy of Sciences , vol.965 , pp. 225-232
    • Virmani, A.1    Gaetani, F.2    Imam, S.3    Binienda, Z.4    Syed, A.L.I.5
  • 79
    • 0034665708 scopus 로고    scopus 로고
    • Direct interactions of METH with the nucleus
    • 11038257 1:CAS:528:DC%2BD3cXmtF2qtrs%3D
    • M Asanuma T Hayashi SV Ordonez N Ogawa JL Cadet 2000 Direct interactions of METH with the nucleus Mol Brain Res 80 237 243 11038257 1:CAS:528: DC%2BD3cXmtF2qtrs%3D
    • (2000) Mol Brain Res , vol.80 , pp. 237-243
    • Asanuma, M.1    Hayashi, T.2    Ordonez, S.V.3    Ogawa, N.4    Cadet, J.L.5
  • 80
    • 0034939055 scopus 로고    scopus 로고
    • Methamphetamine-induced dopaminergic neurotoxicity: Role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts
    • SZ Imam J el-Yazal GD Newport Y Itzhak JL Cadet W Slikker Jr SF Ali 2001 Methamphetamine-induced dopaminergic neurotoxicity: role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts Ann N Y Acad Sci 939 366 380 11462792 1:CAS:528:DC%2BD3MXlsV2ksLk%3D (Pubitemid 32620088)
    • (2001) Annals of the New York Academy of Sciences , vol.939 , pp. 366-380
    • Imam, S.Z.1    El-Yazal, J.2    Newport, G.D.3    Itzhak, Y.4    Cadet, J.L.5    Slikker Jr., W.6    Ali, S.F.7
  • 81
    • 78349253806 scopus 로고    scopus 로고
    • The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy
    • 20738755 1:CAS:528:DC%2BC3cXhsVWgurbK
    • C Nopparat JE Porter M Ebadi P Govitrapong 2010 The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy J Pineal Res 49 382 389 20738755 1:CAS:528:DC%2BC3cXhsVWgurbK
    • (2010) J Pineal Res , vol.49 , pp. 382-389
    • Nopparat, C.1    Porter, J.E.2    Ebadi, M.3    Govitrapong, P.4
  • 82
    • 0031839674 scopus 로고    scopus 로고
    • Effect of melatonin on methamphetamine- and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced dopaminergic neurotoxicity and methamphetamine- induced behavioral sensitization
    • DOI 10.1016/S0028-3908(98)00067-7, PII S0028390898000677
    • Y Itzhak JL Martin MD Black SF Ali 1998 Effect of melatonin on methamphetamine- and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity and methamphetamine-induced behavioral sensitization Neuropharmacology 37 781 791 9707292 1:CAS:528:DyaK1cXkvVCltbk%3D (Pubitemid 28313903)
    • (1998) Neuropharmacology , vol.37 , Issue.6 , pp. 781-791
    • Itzhak, Y.1    Martin, J.L.2    Dean Black, M.3    Ali, S.F.4
  • 83
    • 13544271144 scopus 로고    scopus 로고
    • JNK inhibition as a potential strategy in treating Parkinson's disease
    • DOI 10.1358/dnp.2004.17.10.873916
    • W Wang C Ma Z Mao M Li 2004 JNK inhibition as a potential strategy in treating Parkinson's disease Drug News Perspect 17 646 654 15696229 1:CAS:528:DC%2BD2MXjt12lsb4%3D (Pubitemid 40224050)
    • (2004) Drug News and Perspectives , vol.17 , Issue.10 , pp. 646-654
    • Wang, W.1    Ma, C.2    Mao, Z.3    Li, M.4
  • 84
    • 34447118322 scopus 로고    scopus 로고
    • Melatonin protects SK-N-SH neuroblastoma cells from amphetamine-induced neurotoxicity
    • DOI 10.1111/j.1600-079X.2007.00444.x
    • S Klongpanichapak P Phansuwan-Pujito M Ebadi P Govitrapong 2007 Melatonin protects SK-N-SH neuroblastoma cells from amphetamine-induced neurotoxicity J Pineal Res 43 65 73 17614837 1:CAS:528:DC%2BD2sXosFCjt7c%3D (Pubitemid 47035223)
    • (2007) Journal of Pineal Research , vol.43 , Issue.1 , pp. 65-73
    • Klongpanichapak, S.1    Phansuwan-Pujito, P.2    Ebadi, M.3    Govitrapong, P.4
  • 85
    • 77950644583 scopus 로고    scopus 로고
    • Melatonin attenuates methamphetamine-induced overexpression of pro-inflammatory cytokines in microglial cell lines
    • 20374443 1:CAS:528:DC%2BC3cXltFSltbs%3D
    • J Tocharus C Khonthun S Chongthammakun P Govitrapong 2010 Melatonin attenuates methamphetamine-induced overexpression of pro-inflammatory cytokines in microglial cell lines J Pineal Res 48 347 352 20374443 1:CAS:528: DC%2BC3cXltFSltbs%3D
    • (2010) J Pineal Res , vol.48 , pp. 347-352
    • Tocharus, J.1    Khonthun, C.2    Chongthammakun, S.3    Govitrapong, P.4
  • 86
    • 75149131573 scopus 로고    scopus 로고
    • The protective effect of melatonin on methamphetamine-induced calpain-dependent death pathway in human neuroblastoma SH-SY5Y cultured cells
    • 20050990 1:CAS:528:DC%2BC3cXitFCls7o%3D
    • W Suwanjang P Phansuwan-Pujito P Govitrapong B Chetsawang 2010 The protective effect of melatonin on methamphetamine-induced calpain-dependent death pathway in human neuroblastoma SH-SY5Y cultured cells J Pineal Res 48 94 101 20050990 1:CAS:528:DC%2BC3cXitFCls7o%3D
    • (2010) J Pineal Res , vol.48 , pp. 94-101
    • Suwanjang, W.1    Phansuwan-Pujito, P.2    Govitrapong, P.3    Chetsawang, B.4
  • 87
    • 64649097900 scopus 로고    scopus 로고
    • Melatonin reduces induction of Bax, caspase and cell death in methamphetamine-treated human neuroblastoma SH-SY5Y cultured cells
    • 19386024 1:CAS:528:DC%2BD1MXlsFSqsr4%3D
    • W Wisessmith P Phansuwan-Pujito P Govitrapong B Chetsawang 2009 Melatonin reduces induction of Bax, caspase and cell death in methamphetamine-treated human neuroblastoma SH-SY5Y cultured cells J Pineal Res 46 433 440 19386024 1:CAS:528:DC%2BD1MXlsFSqsr4%3D
    • (2009) J Pineal Res , vol.46 , pp. 433-440
    • Wisessmith, W.1    Phansuwan-Pujito, P.2    Govitrapong, P.3    Chetsawang, B.4
  • 88
    • 59149091414 scopus 로고    scopus 로고
    • Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells
    • 19054297 1:CAS:528:DC%2BD1MXit1Gqurg%3D
    • P Kongsuphol S Mukda C Nopparat A Villarroel P Govitrapong 2009 Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells J Pineal Res 46 199 206 19054297 1:CAS:528:DC%2BD1MXit1Gqurg%3D
    • (2009) J Pineal Res , vol.46 , pp. 199-206
    • Kongsuphol, P.1    Mukda, S.2    Nopparat, C.3    Villarroel, A.4    Govitrapong, P.5
  • 89
    • 67650217579 scopus 로고    scopus 로고
    • Melatonin attenuates methamphetamine-induced reduction of tyrosine hydroxylase, synaptophysin and growth-associated protein-43 levels in the neonatal rat brain
    • 19409439 1:CAS:528:DC%2BD1MXoslSju7g%3D
    • S Kaewsuk K Sae-ung P Phansuwan-Pujito P Govitrapong 2009 Melatonin attenuates methamphetamine-induced reduction of tyrosine hydroxylase, synaptophysin and growth-associated protein-43 levels in the neonatal rat brain Neurochem Int 55 397 405 19409439 1:CAS:528:DC%2BD1MXoslSju7g%3D
    • (2009) Neurochem Int , vol.55 , pp. 397-405
    • Kaewsuk, S.1    Sae-Ung, K.2    Phansuwan-Pujito, P.3    Govitrapong, P.4
  • 90
    • 0031818836 scopus 로고    scopus 로고
    • Melatonin attenuates methamphetamine-induced toxic effects on dopamine and serotonin terminals in mouse brain
    • DOI 10.1002/(SICI)1098-2396(199810)30:2<150::AID-SYN4>3.0.CO;2-B
    • H Hirata M Asanuma JL Cadet 1998 Melatonin attenuates methamphetamine-induced toxic effects on dopamine and serotonin terminals in mouse brain Synapse 30 150 155 9723784 1:CAS:528:DyaK1cXlsVShurY%3D (Pubitemid 28376373)
    • (1998) Synapse , vol.30 , Issue.2 , pp. 150-155
    • Hirata, H.1    Asanuma, M.2    Cadet, J.L.3
  • 92
    • 78650680937 scopus 로고    scopus 로고
    • Melatonin attenuates the amphetamine-induced decrease in vesicular monoamine transporter-2 expression in postnatal rat striatum
    • 21078367 1:CAS:528:DC%2BC3MXhs1GhtQ%3D%3D
    • S Mukda O Vimolratana P Govitrapong 2011 Melatonin attenuates the amphetamine-induced decrease in vesicular monoamine transporter-2 expression in postnatal rat striatum Neurosci Lett 488 154 157 21078367 1:CAS:528: DC%2BC3MXhs1GhtQ%3D%3D
    • (2011) Neurosci Lett , vol.488 , pp. 154-157
    • Mukda, S.1    Vimolratana, O.2    Govitrapong, P.3
  • 93
    • 44649122048 scopus 로고    scopus 로고
    • Melatonin inhibits amphetamine-induced nitric oxide synthase mRNA overexpression in microglial cell lines
    • 18524487 1:CAS:528:DC%2BD1cXmvVKksrk%3D
    • J Tocharus S Chongthammakun P Govitrapong 2008 Melatonin inhibits amphetamine-induced nitric oxide synthase mRNA overexpression in microglial cell lines Neurosci Lett 439 134 137 18524487 1:CAS:528:DC%2BD1cXmvVKksrk%3D
    • (2008) Neurosci Lett , vol.439 , pp. 134-137
    • Tocharus, J.1    Chongthammakun, S.2    Govitrapong, P.3
  • 94
    • 77956390795 scopus 로고    scopus 로고
    • Effect of zinc and paraquat co-exposure on neurodegeneration: Modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats
    • 20553223 1:CAS:528:DC%2BC3cXhtVClu73J
    • A Kumar I Ahmad S Shukla BK Singh DK Patel HP Pandey C Singh 2010 Effect of zinc and paraquat co-exposure on neurodegeneration: modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats Free Radic Res 44 950 965 20553223 1:CAS:528:DC%2BC3cXhtVClu73J
    • (2010) Free Radic Res , vol.44 , pp. 950-965
    • Kumar, A.1    Ahmad, I.2    Shukla, S.3    Singh, B.K.4    Patel, D.K.5    Pandey, H.P.6    Singh, C.7
  • 95
    • 82755192147 scopus 로고    scopus 로고
    • Long-term exposure to cypermethrin induces the nigrostriatal dopaminergic neurodegeneration in adult rats: Postnatal exposure enhances the susceptibility during adulthood
    • Singh AK, Tiwari MN, Upadhyay G, Patel DK, Singh D, Prakash O, Singh MP (2012) Long-term exposure to cypermethrin induces the nigrostriatal dopaminergic neurodegeneration in adult rats: postnatal exposure enhances the susceptibility during adulthood. Neurobiol Aging 33:404-415
    • (2012) Neurobiol Aging , vol.33 , pp. 404-415
    • Singh, A.K.1    Tiwari, M.N.2    Upadhyay, G.3    Patel, D.K.4    Singh, D.5    Prakash, O.6    Singh, M.P.7
  • 96
    • 80051700456 scopus 로고    scopus 로고
    • Nigrostriatal proteomics of cypermethrin-induced dopaminergic neurodegeneration: Microglial activation dependent and independent regulations
    • 21561882 1:CAS:528:DC%2BC3MXhtVeitbrI
    • AK Singh MN Tiwari A Dixit G Upadhyay DK Patel D Singh O Prakash MP Singh 2011 Nigrostriatal proteomics of cypermethrin-induced dopaminergic neurodegeneration: microglial activation dependent and independent regulations Toxicol Sci 122 526 538 21561882 1:CAS:528:DC%2BC3MXhtVeitbrI
    • (2011) Toxicol Sci , vol.122 , pp. 526-538
    • Singh, A.K.1    Tiwari, M.N.2    Dixit, A.3    Upadhyay, G.4    Patel, D.K.5    Singh, D.6    Prakash, O.7    Singh, M.P.8
  • 97
    • 78149268414 scopus 로고    scopus 로고
    • Effects of cypermethrin on monoamine transporters, xenobiotic metabolizing enzymes and lipid peroxidation in the rat nigrostriatal system
    • 20815782 1:CAS:528:DC%2BC3cXhtlOhsr%2FF
    • MN Tiwari AK Singh I Ahmad G Upadhyay D Singh DK Patel C Singh O Prakash MP Singh 2010 Effects of cypermethrin on monoamine transporters, xenobiotic metabolizing enzymes and lipid peroxidation in the rat nigrostriatal system Free Radic Res 44 1416 1424 20815782 1:CAS:528:DC%2BC3cXhtlOhsr%2FF
    • (2010) Free Radic Res , vol.44 , pp. 1416-1424
    • Tiwari, M.N.1    Singh, A.K.2    Ahmad, I.3    Upadhyay, G.4    Singh, D.5    Patel, D.K.6    Singh, C.7    Prakash, O.8    Singh, M.P.9
  • 99
    • 0030016523 scopus 로고    scopus 로고
    • Oxidative damage caused by free radicals produced during catecholamine autoxidation: Protective effects of O-methylation and melatonin
    • DOI 10.1016/0891-5849(96)00033-0
    • JW Miller J Selhub JA Joseph 1996 Oxidative damage caused by free radicals produced during catecholamine autoxidation: protective effects of O-methylation and melatonin Free Radic Biol Med 21 241 249 8818640 1:CAS:528:DyaK28XksFKqtrY%3D (Pubitemid 26255201)
    • (1996) Free Radical Biology and Medicine , vol.21 , Issue.2 , pp. 241-249
    • Miller, J.W.1    Selhub, J.2    Joseph, J.A.3
  • 100
    • 0025235412 scopus 로고
    • Pineal melatonin functions: Possible relevance to Parkinson's disease
    • 2269599 1:STN:280:DyaK3M7gtVWntw%3D%3D
    • R Sandyk 1990 Pineal melatonin functions: possible relevance to Parkinson's disease Int J Neurosci 50 37 53 2269599 1:STN:280: DyaK3M7gtVWntw%3D%3D
    • (1990) Int J Neurosci , vol.50 , pp. 37-53
    • Sandyk, R.1
  • 101
    • 45449117458 scopus 로고    scopus 로고
    • Intraocular microinjections repair experimental Parkinson's disease
    • 18502399 1:CAS:528:DC%2BD1cXnsFCqsrc%3D
    • GL Willis 2008 Intraocular microinjections repair experimental Parkinson's disease Brain Res 1217 119 131 18502399 1:CAS:528: DC%2BD1cXnsFCqsrc%3D
    • (2008) Brain Res , vol.1217 , pp. 119-131
    • Willis, G.L.1
  • 102
    • 0030752296 scopus 로고    scopus 로고
    • Melatonin in relation to cellular antioxidative defense mechanisms
    • RJ Reiter RC Carneiro CS Oh 1997 Melatonin in relation to cellular antioxidative defense mechanisms Horm Metab Res 29 363 372 9288572 1:CAS:528:DyaK2sXlsFGrtbk%3D (Pubitemid 27362059)
    • (1997) Hormone and Metabolic Research , vol.29 , Issue.8 , pp. 363-372
    • Reiter, R.J.1    Carneiro, R.C.2    Oh, C.-S.3
  • 103
    • 0025402221 scopus 로고
    • The significance of eye blink rate in Parkinsonism: A hypothesis
    • 2265915 1:STN:280:DyaK3M%2Fpt1Okuw%3D%3D
    • R Sandyk 1990 The significance of eye blink rate in Parkinsonism: a hypothesis Int J Neurosci 51 99 103 2265915 1:STN:280:DyaK3M%2Fpt1Okuw%3D%3D
    • (1990) Int J Neurosci , vol.51 , pp. 99-103
    • Sandyk, R.1
  • 104
  • 105
    • 0036482282 scopus 로고    scopus 로고
    • Chemical and physical properties and potential mechanisms: Melatonin as a broad spectrum antioxidant and free radical scavenger
    • 11899100 1:CAS:528:DC%2BD38XhvVaqu7Y%3D
    • DX Tan RJ Reiter LC Manchester MT Yan M El-Sawi RM Sainz JC Mayo R Kohen M Allegra R Hardeland 2002 Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger Curr Top Med Chem 2 181 197 11899100 1:CAS:528:DC%2BD38XhvVaqu7Y%3D
    • (2002) Curr Top Med Chem , vol.2 , pp. 181-197
    • Tan, D.X.1    Reiter, R.J.2    Manchester, L.C.3    Yan, M.T.4    El-Sawi, M.5    Sainz, R.M.6    Mayo, J.C.7    Kohen, R.8    Allegra, M.9    Hardeland, R.10
  • 106
    • 0033859916 scopus 로고    scopus 로고
    • Comparative effects of melatonin, L-deprenyl, Trolox and ascorbate in the suppression of hydroxyl radical formation during dopamine autoxidation in vitro
    • 10981823 1:CAS:528:DC%2BD3cXmtlejtb8%3D
    • H Khaldy G Escames J León F Vives JD Luna D Acuña- Castroviejo 2000 Comparative effects of melatonin, L-deprenyl, Trolox and ascorbate in the suppression of hydroxyl radical formation during dopamine autoxidation in vitro J Pineal Res 29 100 107 10981823 1:CAS:528: DC%2BD3cXmtlejtb8%3D
    • (2000) J Pineal Res , vol.29 , pp. 100-107
    • Khaldy, H.1    Escames, G.2    León, J.3    Vives, F.4    Luna, J.D.5    Acuña-Castroviejo, D.6
  • 107
    • 0037405378 scopus 로고    scopus 로고
    • Synergistic effects of melatonin and deprenyl against MPTP-induced mitochondrial damage and DA depletion
    • DOI 10.1016/S0197-4580(02)00133-1, PII S0197458002001331
    • H Khaldy G Escames J Leon L Bikjdaouene D Acuña-Castroviejo 2003 Synergistic effects of melatonin and deprenyl against MPTP-induced mitochondrial damage and DA depletion Neurobiol Aging 24 491 500 12600724 1:CAS:528:DC%2BD3sXhsVanur8%3D (Pubitemid 36205054)
    • (2003) Neurobiology of Aging , vol.24 , Issue.3 , pp. 491-500
    • Khaldy, H.1    Escames, G.2    Leon, J.3    Bikjdaouene, L.4    Acuna-Castroviejo, D.5
  • 108
    • 79959523987 scopus 로고    scopus 로고
    • Circadian modulation of sodium-potassium ATPase and sodium-proton exchanger in human erythrocytes: In vitro effect of melatonin
    • 21366966 1:CAS:528:DC%2BC3MXjtFajtbY%3D Noisy-le-grand
    • S Chakravarty SI Rizvi 2011 Circadian modulation of sodium-potassium ATPase and sodium-proton exchanger in human erythrocytes: in vitro effect of melatonin Cell Mol Biol 57 80 86 21366966 1:CAS:528:DC%2BC3MXjtFajtbY%3D Noisy-le-grand
    • (2011) Cell Mol Biol , vol.57 , pp. 80-86
    • Chakravarty, S.1    Rizvi, S.I.2
  • 109
    • 79959401376 scopus 로고    scopus 로고
    • Day and night GSH and MDA levels in healthy adults and effects of different doses of melatonin on these parameters
    • 21647290
    • S Chakravarty SI Rizvi 2011 Day and night GSH and MDA levels in healthy adults and effects of different doses of melatonin on these parameters Int J Cell Biol 2011 404591 21647290
    • (2011) Int J Cell Biol , vol.2011 , pp. 404591
    • Chakravarty, S.1    Rizvi, S.I.2
  • 110
    • 0038727646 scopus 로고    scopus 로고
    • Gene and protein expression profiles of anti- and pro-apoptotic actions of dopamine, R-apomorphine, green tea polyphenol (-)-epigallocatechine-3- gallate, and melatonin
    • O Weinreb S Mandel MB Youdim 2003 Gene and protein expression profiles of anti- and pro-apoptotic actions of dopamine, R-apomorphine, green tea polyphenol (-)-epigallocatechine-3-gallate, and melatonin Ann N Y Acad Sci 993 351 361 12853328 1:CAS:528:DC%2BD3sXmtVajsLg%3D (Pubitemid 36808465)
    • (2003) Annals of the New York Academy of Sciences , vol.993 , pp. 351-361
    • Weinreb, O.1    Mandel, S.2    Youdim, M.B.H.3
  • 111
    • 0031981981 scopus 로고    scopus 로고
    • N-acetyl-serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF-κB
    • DOI 10.1111/j.1600-079X.1998.tb00530.x
    • F Lezoualc'h M Sparapani C Behl 1998 N-acetyl-serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF-kappaB J Pineal Res 24 168 178 9551854 (Pubitemid 28156602)
    • (1998) Journal of Pineal Research , vol.24 , Issue.3 , pp. 168-178
    • Lezoualc'h, F.1    Sparapani, M.2    Behl, C.3
  • 112
    • 0037016713 scopus 로고    scopus 로고
    • Melatonin receptor activation regulates GnRH gene expression and secretion in GT1-7 GnRH neurons. Signal transduction mechanisms
    • DOI 10.1074/jbc.M108890200
    • D Roy DD Belsham 2002 Melatonin receptor activation regulates GnRH gene expression and secretion in GT1-7 GnRH neurons. Signal transduction mechanisms J Biol Chem 277 251 258 11684691 1:CAS:528:DC%2BD38XjslGjtg%3D%3D (Pubitemid 34952052)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.1 , pp. 251-258
    • Roy, D.1    Belsham, D.D.2
  • 113
    • 0037203546 scopus 로고    scopus 로고
    • Akt: Versatile mediator of cell survival and beyond
    • D Kim J Chung 2002 Akt: versatile mediator of cell survival and beyond J Biochem Mol Biol 35 106 115 16248975 1:CAS:528:DC%2BD38XhtlWmu78%3D (Pubitemid 35216586)
    • (2002) Journal of Biochemistry and Molecular Biology , vol.35 , Issue.1 , pp. 106-115
    • Kim, D.1    Chung, J.2
  • 114
    • 44349111685 scopus 로고    scopus 로고
    • Melatonin induces Akt phosphorylation through melatonin receptor- and PI3K-dependent pathways in primary astrocytes
    • 20157392 1:CAS:528:DC%2BD1cXntFOrurs%3D
    • PJ Kong JS Byun SY Lim JJ Lee SJ Hong KJ Kwon SS Kim 2008 Melatonin induces Akt phosphorylation through melatonin receptor- and PI3K-dependent pathways in primary astrocytes Korean J Physiol Pharmacol 12 37 41 20157392 1:CAS:528:DC%2BD1cXntFOrurs%3D
    • (2008) Korean J Physiol Pharmacol , vol.12 , pp. 37-41
    • Kong, P.J.1    Byun, J.S.2    Lim, S.Y.3    Lee, J.J.4    Hong, S.J.5    Kwon, K.J.6    Kim, S.S.7
  • 115
    • 33644908054 scopus 로고    scopus 로고
    • Sustained activation of Akt by melatonin contributes to the protection against kainic acid-induced neuronal death in hippocampus
    • 16313502 1:CAS:528:DC%2BD28Xhs1Gnu78%3D
    • SH Lee W Chun PJ Kong JA Han BP Cho OY Kwon HJ Lee SS Kim 2006 Sustained activation of Akt by melatonin contributes to the protection against kainic acid-induced neuronal death in hippocampus J Pineal Res 40 79 85 16313502 1:CAS:528:DC%2BD28Xhs1Gnu78%3D
    • (2006) J Pineal Res , vol.40 , pp. 79-85
    • Lee, S.H.1    Chun, W.2    Kong, P.J.3    Han, J.A.4    Cho, B.P.5    Kwon, O.Y.6    Lee, H.J.7    Kim, S.S.8
  • 116
    • 12344307153 scopus 로고    scopus 로고
    • Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice
    • DOI 10.1111/j.1600-079X.2004.00178.x
    • U Kilic E Kilic RJ Reiter CL Bassetti DM Hermann 2005 Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice J Pineal Res 38 67 71 15617539 1:CAS:528:DC%2BD2MXpsFertA%3D%3D (Pubitemid 40139312)
    • (2005) Journal of Pineal Research , vol.38 , Issue.1 , pp. 67-71
    • Kilic, U.1    Kilic, E.2    Reiter, R.J.3    Bassetti, C.L.4    Hermann, D.M.5
  • 117
    • 31344477300 scopus 로고    scopus 로고
    • Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease
    • DOI 10.1016/j.brainres.2005.10.084, PII S0006899305015404
    • R Sharma CR McMillan CC Tenn LP Niles 2006 Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease Brain Res 1068 230 236 16375867 1:CAS:528:DC%2BD28Xos1Wrsg%3D%3D (Pubitemid 43139282)
    • (2006) Brain Research , vol.1068 , Issue.1 , pp. 230-236
    • Sharma, R.1    McMillan, C.R.2    Tenn, C.C.3    Niles, L.P.4
  • 119
    • 0037171033 scopus 로고    scopus 로고
    • Induction of GDNF mRNA expression by melatonin in rat C6 glioma cells
    • KJ Armstrong LP Niles 2002 Induction of GDNF mRNA expression by melatonin in rat C6 glioma cells Neuroreport 13 473 475 11930164 1:CAS:528: DC%2BD38XnsFKku7s%3D (Pubitemid 34293193)
    • (2002) NeuroReport , vol.13 , Issue.4 , pp. 473-475
    • Armstrong, K.J.1    Niles, L.P.2
  • 120
    • 76049109954 scopus 로고    scopus 로고
    • Melatonin MT1 and MT2 receptor expression in Parkinson's disease
    • 20110911 1:CAS:528:DC%2BC3cXktF2mur4%3D
    • N Adi DC Mash Y Ali C Singer L Shehadeh S Papapetropoulos 2010 Melatonin MT1 and MT2 receptor expression in Parkinson's disease Med Sci Monit 16 BR61 BR67 20110911 1:CAS:528:DC%2BC3cXktF2mur4%3D
    • (2010) Med Sci Monit , vol.16
    • Adi, N.1    Mash, D.C.2    Ali, Y.3    Singer, C.4    Shehadeh, L.5    Papapetropoulos, S.6
  • 122
    • 33644869714 scopus 로고    scopus 로고
    • Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: Meta-analysis
    • 16473858 1:CAS:528:DC%2BD28XisFGqsr0%3D
    • N Buscemi B Vandermeer N Hooton R Pandya L Tjosvold L Hartling S Vohra TP Klassen G Baker 2006 Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis BMJ 332 385 393 16473858 1:CAS:528:DC%2BD28XisFGqsr0%3D
    • (2006) BMJ , vol.332 , pp. 385-393
    • Buscemi, N.1    Vandermeer, B.2    Hooton, N.3    Pandya, R.4    Tjosvold, L.5    Hartling, L.6    Vohra, S.7    Klassen, T.P.8    Baker, G.9
  • 123
    • 79954548208 scopus 로고    scopus 로고
    • Melatonin and aging: Prospects for human treatment
    • 21451205 1:CAS:528:DC%2BC3MXmtFagsrg%3D
    • GA Bubenik SJ Konturek 2011 Melatonin and aging: prospects for human treatment J Physiol Pharmacol 62 13 19 21451205 1:CAS:528:DC%2BC3MXmtFagsrg%3D
    • (2011) J Physiol Pharmacol , vol.62 , pp. 13-19
    • Bubenik, G.A.1    Konturek, S.J.2
  • 125
    • 33645500581 scopus 로고    scopus 로고
    • Circulating melatonin levels: Possible link between Parkinson's disease and cancer risk?
    • 16596313
    • E Schernhammer H Chen B Ritz 2006 Circulating melatonin levels: possible link between Parkinson's disease and cancer risk? Cancer Causes Control 17 577 582 16596313
    • (2006) Cancer Causes Control , vol.17 , pp. 577-582
    • Schernhammer, E.1    Chen, H.2    Ritz, B.3
  • 126
    • 70349126206 scopus 로고    scopus 로고
    • Potential influences of complementary therapy on motor and non-motor complications in Parkinson's disease
    • 19739693 1:CAS:528:DC%2BD1MXhsVOgtr7F
    • TA Zesiewicz ML Evatt 2009 Potential influences of complementary therapy on motor and non-motor complications in Parkinson's disease CNS Drugs 23 817 835 19739693 1:CAS:528:DC%2BD1MXhsVOgtr7F
    • (2009) CNS Drugs , vol.23 , pp. 817-835
    • Zesiewicz, T.A.1    Evatt, M.L.2
  • 127
    • 34548416796 scopus 로고    scopus 로고
    • Neural stem cell transplantation and melatonin treatment in a 6-hydroxydopamine model of Parkinson's disease
    • DOI 10.1111/j.1600-079X.2007.00469.x
    • R Sharma CR Mcmillan LP Niles 2007 Neural stem cell transplantation and melatonin treatment in a 6-hydroxydopamine model of Parkinson's disease J Pineal Res 43 245 254 17803521 1:CAS:528:DC%2BD2sXhtFKjt7bI (Pubitemid 47353003)
    • (2007) Journal of Pineal Research , vol.43 , Issue.3 , pp. 245-254
    • Sharma, R.1    McMillan, C.R.2    Niles, L.P.3
  • 129
    • 71549120441 scopus 로고    scopus 로고
    • Visualization of melatonin's multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes
    • 19925580 1:CAS:528:DC%2BD1MXhs1WhtLzK
    • MJ Jou TI Peng LF Hsu SB Jou RJ Reiter CM Yang CC Chiao YF Lin CC Chen 2010 Visualization of melatonin's multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes J Pineal Res 48 20 38 19925580 1:CAS:528:DC%2BD1MXhs1WhtLzK
    • (2010) J Pineal Res , vol.48 , pp. 20-38
    • Jou, M.J.1    Peng, T.I.2    Hsu, L.F.3    Jou, S.B.4    Reiter, R.J.5    Yang, C.M.6    Chiao, C.C.7    Lin, Y.F.8    Chen, C.C.9
  • 130
    • 33745784192 scopus 로고    scopus 로고
    • Recent developments of melatonin related antioxidant compounds
    • DOI 10.2174/138620706777698553
    • S Suzen 2006 Recent developments of melatonin related antioxidant compounds Comb Chem High Throughput Screen 9 409 419 16842222 1:CAS:528:DC%2BD28XmvVCgu7c%3D (Pubitemid 44024698)
    • (2006) Combinatorial Chemistry and High Throughput Screening , vol.9 , Issue.6 , pp. 409-419
    • Suzen, S.1
  • 131
    • 0003736648 scopus 로고    scopus 로고
    • Neuroprotective strategies in Parkinson's disease: Protection against progressive nigral damage induced by free radicals
    • 16787846 1:CAS:528:DC%2BD3cXot1Cqs7Y%3D
    • CC Chiueh T Andoh AR Lai E Lai G Krishna 2000 Neuroprotective strategies in Parkinson's disease: protection against progressive nigral damage induced by free radicals Neurotox Res 2 293 310 16787846 1:CAS:528:DC%2BD3cXot1Cqs7Y%3D
    • (2000) Neurotox Res , vol.2 , pp. 293-310
    • Chiueh, C.C.1    Andoh, T.2    Lai, A.R.3    Lai, E.4    Krishna, G.5


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