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Volumn 48, Issue 1, 2010, Pages 20-38

Visualization of melatonin's multiple mitochondrial levels of protection against mitochondrial Ca2+-mediated permeability transition and beyond in rat brain astrocytes

Author keywords

Apoptosis; Astrocyte; MCa2+; Melatonin; Mitochondrial permeability transition; MROS

Indexed keywords

ALPHA TOCOPHEROL; CALCIUM ION; CYCLOSPORIN A; IONOMYCIN; MELATONIN; REACTIVE OXYGEN METABOLITE;

EID: 71549120441     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2009.00721.x     Document Type: Article
Times cited : (151)

References (63)
  • 1
    • 62249207349 scopus 로고    scopus 로고
    • Melatonin in relation to the "strong" and "weak" versions of the free radical theory of aging
    • Reiter RJ, Paredes SD, Korkmaz A et al. Melatonin in relation to the "strong" and "weak" versions of the free radical theory of aging. Adv Med Sci 2008 53 : 119 129.
    • (2008) Adv Med Sci , vol.53 , pp. 119-129
    • Reiter, R.J.1    Paredes, S.D.2    Korkmaz, A.3
  • 2
    • 34147201601 scopus 로고    scopus 로고
    • AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice
    • Manda K, Ueno M, Anzai K. AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. J Pineal Res 2007 42 : 386 393.
    • (2007) J Pineal Res , vol.42 , pp. 386-393
    • Manda, K.1    Ueno, M.2    Anzai, K.3
  • 3
    • 54349089838 scopus 로고    scopus 로고
    • Biogenic amines in the reduction of oxidative stress: Melatonin and its metabolites
    • Reiter RJ, Tan DX, Jou MJ et al. Biogenic amines in the reduction of oxidative stress: melatonin and its metabolites. Neuro Endocrinol Lett 2008 29 : 391 398.
    • (2008) Neuro Endocrinol Lett , vol.29 , pp. 391-398
    • Reiter, R.J.1    Tan, D.X.2    Jou, M.J.3
  • 4
    • 33845536018 scopus 로고    scopus 로고
    • One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?
    • Tan DX, Manchester LC, Terron MP et al. One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res 2007 42 : 28 42.
    • (2007) J Pineal Res , vol.42 , pp. 28-42
    • Tan, D.X.1    Manchester, L.C.2    Terron, M.P.3
  • 5
    • 51649122293 scopus 로고    scopus 로고
    • Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species
    • Peyrot F, Ducrocq C. Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species. J Pineal Res 2008 45 : 235 246.
    • (2008) J Pineal Res , vol.45 , pp. 235-246
    • Peyrot, F.1    Ducrocq, C.2
  • 6
    • 0002979059 scopus 로고
    • Melatonin: A potent, endogenous hydroxyl radical scavenger
    • Tan DX, Chen LD, Poeggeler B et al. Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocrinol J 1993 1 : 57 60.
    • (1993) Endocrinol J , vol.1 , pp. 57-60
    • Tan, D.X.1    Chen, L.D.2    Poeggeler, B.3
  • 7
    • 68249129060 scopus 로고    scopus 로고
    • Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgotten class of biogenic amines
    • Hardeland R, Tan DX, Reiter RJ. Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res 2009 47 : 109 126.
    • (2009) J Pineal Res , vol.47 , pp. 109-126
    • Hardeland, R.1    Tan, D.X.2    Reiter, R.J.3
  • 8
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen species
    • Turrens JF. Mitochondrial formation of reactive oxygen species. The J Physiol 2003 552 : 335 344.
    • (2003) The J Physiol , vol.552 , pp. 335-344
    • Turrens, J.F.1
  • 9
    • 0035110424 scopus 로고    scopus 로고
    • Melatonin, mitochondria, and cellular bioenergetics
    • Acuna-Castroviejo D, Martin M, Macias M et al. Melatonin, mitochondria, and cellular bioenergetics. J Pineal Res 2001 30 : 65 74.
    • (2001) J Pineal Res , vol.30 , pp. 65-74
    • Acuna-Castroviejo, D.1    Martin, M.2    MacIas, M.3
  • 11
    • 3242664824 scopus 로고    scopus 로고
    • Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes
    • Jou MJ, Peng TI, Reiter RJ et al. Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes. J Pineal Res 2004 37 : 55 70.
    • (2004) J Pineal Res , vol.37 , pp. 55-70
    • Jou, M.J.1    Peng, T.I.2    Reiter, R.J.3
  • 12
    • 0036425961 scopus 로고    scopus 로고
    • Critical role of mitochondrial reactive oxygen species formation in visible laser irradiation-induced apoptosis in rat brain astrocytes (RBA-1)
    • Jou MJ, Jou SB, Chen HM et al. Critical role of mitochondrial reactive oxygen species formation in visible laser irradiation-induced apoptosis in rat brain astrocytes (RBA-1). J Biomed Sci 2002 9 : 507 516.
    • (2002) J Biomed Sci , vol.9 , pp. 507-516
    • Jou, M.J.1    Jou, S.B.2    Chen, H.M.3
  • 13
    • 2342469840 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species generation and calcium increase induced by visible light in astrocytes
    • Jou MJ, Jou SB, Guo MJ et al. Mitochondrial reactive oxygen species generation and calcium increase induced by visible light in astrocytes. Ann N Y Acad Sci 2004 1011 : 45 56.
    • (2004) Ann N y Acad Sci , vol.1011 , pp. 45-56
    • Jou, M.J.1    Jou, S.B.2    Guo, M.J.3
  • 14
    • 34848919892 scopus 로고    scopus 로고
    • Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis
    • Jou MJ, Peng TI, Yu PZ et al. Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis. J Pineal Res 2007 43 : 389 403.
    • (2007) J Pineal Res , vol.43 , pp. 389-403
    • Jou, M.J.1    Peng, T.I.2    Yu, P.Z.3
  • 15
    • 29344444706 scopus 로고    scopus 로고
    • Visualizing common deletion of mitochondrial DNA-augmented mitochondrial reactive oxygen species generation and apoptosis upon oxidative stress
    • Peng TI, Yu PR, Chen JY et al. Visualizing common deletion of mitochondrial DNA-augmented mitochondrial reactive oxygen species generation and apoptosis upon oxidative stress. Biochim Biophys Acta 2006 1762 : 241 255.
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 241-255
    • Peng, T.I.1    Yu, P.R.2    Chen, J.Y.3
  • 16
    • 22044456754 scopus 로고    scopus 로고
    • Enhanced generation of mitochondrial reactive oxygen species in cybrids containing 4977-bp mitochondrial DNA deletion
    • Jou MJ, Peng TI, Wu HY et al. Enhanced generation of mitochondrial reactive oxygen species in cybrids containing 4977-bp mitochondrial DNA deletion. Ann N Y Acad Sci 2005 1042 : 221 228.
    • (2005) Ann N y Acad Sci , vol.1042 , pp. 221-228
    • Jou, M.J.1    Peng, T.I.2    Wu, H.Y.3
  • 17
    • 0029863399 scopus 로고    scopus 로고
    • Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites
    • Costantini P, Chernyak BV, Petronilli V et al. Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites. J Biol Chem 1996 271 : 6746 6751.
    • (1996) J Biol Chem , vol.271 , pp. 6746-6751
    • Costantini, P.1    Chernyak, B.V.2    Petronilli, V.3
  • 18
    • 0032551769 scopus 로고    scopus 로고
    • Induction of the mitochondrial permeability transition by N-ethylmaleimide depends on secondary oxidation of critical thiol groups. Potentiation by copper-ortho-phenanthroline without dimerization of the adenine nucleotide translocase
    • Costantini P, Colonna R, Bernardi P. Induction of the mitochondrial permeability transition by N-ethylmaleimide depends on secondary oxidation of critical thiol groups. Potentiation by copper-ortho-phenanthroline without dimerization of the adenine nucleotide translocase. Biochim Biophys Acta 1998 1365 : 385 392.
    • (1998) Biochim Biophys Acta , vol.1365 , pp. 385-392
    • Costantini, P.1    Colonna, R.2    Bernardi, P.3
  • 19
    • 33646255246 scopus 로고    scopus 로고
    • The mitochondrial permeability transition from in vitro artifact to disease target
    • Bernardi P, Krauskopf A, Basso E et al. The mitochondrial permeability transition from in vitro artifact to disease target. FEBS J 2006 273 : 2077 2099.
    • (2006) FEBS J , vol.273 , pp. 2077-2099
    • Bernardi, P.1    Krauskopf, A.2    Basso, E.3
  • 20
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • DOI 10.1152/physrev.00013.2006
    • Kroemer G, Galluzzi L, Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol Rev 2007 87 : 99 163. (Pubitemid 46209992)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 21
    • 0032827410 scopus 로고    scopus 로고
    • Mitochondrial transport of cations: Channels, exchangers, and permeability transition
    • Bernardi P. Mitochondrial transport of cations: channels, exchangers, and permeability transition. Physiol Rev 1999 79 : 1127 1155.
    • (1999) Physiol Rev , vol.79 , pp. 1127-1155
    • Bernardi, P.1
  • 22
    • 0031659950 scopus 로고    scopus 로고
    • Mitochondrial function as a determinant of recovery or death in cell response to injury
    • Di Lisa F, Bernardi P. Mitochondrial function as a determinant of recovery or death in cell response to injury. Mol Cell Biochem 1998 184 : 379 391.
    • (1998) Mol Cell Biochem , vol.184 , pp. 379-391
    • Di Lisa, F.1    Bernardi, P.2
  • 23
    • 0029960727 scopus 로고    scopus 로고
    • Histamine induces oscillations of mitochondrial free Ca2 + concentration in single cultured rat brain astrocytes
    • Jou MJ, Peng TI, Sheu SS. Histamine induces oscillations of mitochondrial free Ca2 + concentration in single cultured rat brain astrocytes. J Physiol 1996 2 : 299 308.
    • (1996) J Physiol , vol.2 , pp. 299-308
    • Jou, M.J.1    Peng, T.I.2    Sheu, S.S.3
  • 24
    • 0031839233 scopus 로고    scopus 로고
    • Privileged access to mitochondria of calcium influx through N-methyl-D-aspartate receptors
    • Peng TI, Greenamyre JT. Privileged access to mitochondria of calcium influx through N-methyl-D-aspartate receptors. Mol Pharmacol 1998 53 : 974 980.
    • (1998) Mol Pharmacol , vol.53 , pp. 974-980
    • Peng, T.I.1    Greenamyre, J.T.2
  • 25
    • 0031890041 scopus 로고    scopus 로고
    • Visualization of NMDA receptor-induced mitochondrial calcium accumulation in striatal neurons
    • Peng TI, Jou MJ, Sheu SS et al. Visualization of NMDA receptor-induced mitochondrial calcium accumulation in striatal neurons. Exp Neurol 1998 149 : 1 12.
    • (1998) Exp Neurol , vol.149 , pp. 1-12
    • Peng, T.I.1    Jou, M.J.2    Sheu, S.S.3
  • 26
    • 0036488223 scopus 로고    scopus 로고
    • Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation
    • Alano CC, Beutner G, Dirksen RT et al. Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation. J Neurochem 2002 80 : 531 538.
    • (2002) J Neurochem , vol.80 , pp. 531-538
    • Alano, C.C.1    Beutner, G.2    Dirksen, R.T.3
  • 27
    • 3142713361 scopus 로고    scopus 로고
    • Direct inhibition of the mitochondrial permeability transition pore: A possible mechanism responsible for anti-apoptotic effects of melatonin
    • Andrabi SA, Sayeed I, Siemen D et al. Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin. FASEB J 2004 18 : 869 871.
    • (2004) FASEB J , vol.18 , pp. 869-871
    • Andrabi, S.A.1    Sayeed, I.2    Siemen, D.3
  • 28
    • 31144454069 scopus 로고    scopus 로고
    • Photosensitizer targeting: Mitochondrion-targeted photosensitizer enhances mitochondrial reactive oxygen species and mitochondrial calcium-mediated apoptosis
    • Peng TI, Chang CJ, Jou SB et al. Photosensitizer targeting: mitochondrion-targeted photosensitizer enhances mitochondrial reactive oxygen species and mitochondrial calcium-mediated apoptosis. Optical Quant Electr 2005 37 : 1377 1584.
    • (2005) Optical Quant Electr , vol.37 , pp. 1377-1584
    • Peng, T.I.1    Chang, C.J.2    Jou, S.B.3
  • 29
    • 0026801183 scopus 로고
    • Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization
    • Bernardi P. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization. J Biol Chem 1992 267 : 8834 8839.
    • (1992) J Biol Chem , vol.267 , pp. 8834-8839
    • Bernardi, P.1
  • 30
    • 0027207302 scopus 로고
    • Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation
    • Nicolli A, Petronilli V, Bernardi P. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation. Biochemistry 1993 32 : 4461 4465. (Pubitemid 23137757)
    • (1993) Biochemistry , vol.32 , Issue.16 , pp. 4461-4465
    • Nicolli, A.1    Petronilli, V.2    Bernardi, P.3
  • 32
    • 0024360271 scopus 로고
    • Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria
    • Broekemeier KM, Dempsey ME, Pfeiffer DR. Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J Biol Chem 1989 264 : 7826 7830.
    • (1989) J Biol Chem , vol.264 , pp. 7826-7830
    • Broekemeier, K.M.1    Dempsey, M.E.2    Pfeiffer, D.R.3
  • 33
    • 0023821864 scopus 로고
    • 2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress
    • 2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress. Biochem J 1988 255 : 357 360.
    • (1988) Biochem J , vol.255 , pp. 357-360
    • Crompton, M.1    Ellinger, H.2    Costi, A.3
  • 34
    • 0023263612 scopus 로고
    • Action of cyclosporine on mitochondrial calcium fluxes
    • Fournier N, Ducet G, Crevat A. Action of cyclosporine on mitochondrial calcium fluxes. J Bioenerg Biomembr 1987 19 : 297 303.
    • (1987) J Bioenerg Biomembr , vol.19 , pp. 297-303
    • Fournier, N.1    Ducet, G.2    Crevat, A.3
  • 35
    • 0022109068 scopus 로고
    • Properties of rat brain astrocytes in long-term culture
    • Jou TC, Jou MJ, Chen JY et al. Properties of rat brain astrocytes in long-term culture. J Formosan Med Assoc 1985 84 : 865 881.
    • (1985) J Formosan Med Assoc , vol.84 , pp. 865-881
    • Jou, T.C.1    Jou, M.J.2    Chen, J.Y.3
  • 36
    • 2342656889 scopus 로고    scopus 로고
    • Mitochondrial swelling and generation of reactive oxygen species induced by photoirradiation are heterogeneously distributed
    • Peng TI, Jou MJ. Mitochondrial swelling and generation of reactive oxygen species induced by photoirradiation are heterogeneously distributed. Ann N Y Acad Sci 2004 1011 : 112 122.
    • (2004) Ann N y Acad Sci , vol.1011 , pp. 112-122
    • Peng, T.I.1    Jou, M.J.2
  • 37
    • 0037059833 scopus 로고    scopus 로고
    • Ligand-selective modulation of the permeability transition pore by arginine modification. Opposing effects of p-hydroxyphenylglyoxal and phenylglyoxal
    • Linder MD, Morkunaite-Haimi S, Kinnunen PK et al. Ligand-selective modulation of the permeability transition pore by arginine modification. Opposing effects of p-hydroxyphenylglyoxal and phenylglyoxal. J Biol Chem 2002 277 : 937 942.
    • (2002) J Biol Chem , vol.277 , pp. 937-942
    • Linder, M.D.1    Morkunaite-Haimi, S.2    Kinnunen, P.K.3
  • 38
    • 20144389194 scopus 로고    scopus 로고
    • Modification of permeability transition pore arginine(s) by phenylglyoxal derivatives in isolated mitochondria and mammalian cells. Structure-function relationship of arginine ligands
    • Johans M, Milanesi E, Franck M et al. Modification of permeability transition pore arginine(s) by phenylglyoxal derivatives in isolated mitochondria and mammalian cells. Structure-function relationship of arginine ligands. J Biol Chem 2005 280 : 12130 12136.
    • (2005) J Biol Chem , vol.280 , pp. 12130-12136
    • Johans, M.1    Milanesi, E.2    Franck, M.3
  • 39
    • 0842307483 scopus 로고    scopus 로고
    • The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
    • Kokoszka JE, Waymire KG, Levy SE et al. The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 2004 427 : 461 465.
    • (2004) Nature , vol.427 , pp. 461-465
    • Kokoszka, J.E.1    Waymire, K.G.2    Levy, S.E.3
  • 40
    • 0025195166 scopus 로고
    • 2+ as a second messenger within mitochondria of the heart and other tissues
    • 2+ as a second messenger within mitochondria of the heart and other tissues. Annu Rev Physiol 1990 52 : 451 466.
    • (1990) Annu Rev Physiol , vol.52 , pp. 451-466
    • Denton, R.M.1    McCormack, J.G.2
  • 41
    • 0026611419 scopus 로고
    • 2[125I]iodomelatonin binding sites in spleens of guinea pigs
    • Poon AM, Pang SF. 2[125I]iodomelatonin binding sites in spleens of guinea pigs. Life Sci 1992 50 : 1719 1726.
    • (1992) Life Sci , vol.50 , pp. 1719-1726
    • Poon, A.M.1    Pang, S.F.2
  • 42
    • 0027725205 scopus 로고
    • Distribution of melatonin in mammalian tissues: The relative importance of nuclear versus cytosolic localization
    • Menendez-Pelaez A, Reiter RJ. Distribution of melatonin in mammalian tissues: the relative importance of nuclear versus cytosolic localization. J Pineal Res 1993 15 : 59 69.
    • (1993) J Pineal Res , vol.15 , pp. 59-69
    • Menendez-Pelaez, A.1    Reiter, R.J.2
  • 43
    • 0034193996 scopus 로고    scopus 로고
    • The biosynthesis and functional role of cardiolipin
    • Schlame M, Rua D, Greenberg ML. The biosynthesis and functional role of cardiolipin. Prog Lipid Res 2000 39 : 257 288.
    • (2000) Prog Lipid Res , vol.39 , pp. 257-288
    • Schlame, M.1    Rua, D.2    Greenberg, M.L.3
  • 44
    • 33846272138 scopus 로고    scopus 로고
    • Role of cardiolipin alterations in mitochondrial dysfunction and disease
    • Chicco AJ, Sparagna GC. Role of cardiolipin alterations in mitochondrial dysfunction and disease. Am J Physiol Cell Physiol 2007 292 : C33 C44.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Chicco, A.J.1    Sparagna, G.C.2
  • 45
    • 33750623680 scopus 로고    scopus 로고
    • 2+ on cardiolipin-cytochrome c interaction
    • 2+ on cardiolipin-cytochrome c interaction. Biochim Biophys Acta 2006 1760 : 1827 1830.
    • (2006) Biochim Biophys Acta , vol.1760 , pp. 1827-1830
    • Huang, Y.1    Liu, L.2    Shi, C.3
  • 46
    • 14044268132 scopus 로고    scopus 로고
    • Redox mechanisms of cytoprotection by Bcl-2
    • Kowaltowski AJ, Fiskum G. Redox mechanisms of cytoprotection by Bcl-2. Antioxid Redox Signal 2005 7 : 508 514.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 508-514
    • Kowaltowski, A.J.1    Fiskum, G.2
  • 47
    • 0029950290 scopus 로고    scopus 로고
    • Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
    • Susin SA, Zamzami N, Castedo M et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996 184 : 1331 1341.
    • (1996) J Exp Med , vol.184 , pp. 1331-1341
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3
  • 48
    • 9444243810 scopus 로고    scopus 로고
    • Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2
    • Ellerby LM, Ellerby HM, Park SM et al. Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2. J Neurochem 1996 67 : 1259 1267.
    • (1996) J Neurochem , vol.67 , pp. 1259-1267
    • Ellerby, L.M.1    Ellerby, H.M.2    Park, S.M.3
  • 49
    • 85047695800 scopus 로고    scopus 로고
    • A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
    • Trinei M, Giorgio M, Cicalese A et al. A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. Oncogene 2002 21 : 3872 3878.
    • (2002) Oncogene , vol.21 , pp. 3872-3878
    • Trinei, M.1    Giorgio, M.2    Cicalese, A.3
  • 50
    • 22744447211 scopus 로고    scopus 로고
    • Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
    • Giorgio M, Migliaccio E, Orsini F et al. Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell 2005 122 : 221 233.
    • (2005) Cell , vol.122 , pp. 221-233
    • Giorgio, M.1    Migliaccio, E.2    Orsini, F.3
  • 51
    • 0141867841 scopus 로고    scopus 로고
    • New roles for astrocytes: Regulation of synaptic transmission
    • Newman EA. New roles for astrocytes: regulation of synaptic transmission. Trends Neurosci 2003 26 : 536 542.
    • (2003) Trends Neurosci , vol.26 , pp. 536-542
    • Newman, E.A.1
  • 52
    • 23044435896 scopus 로고    scopus 로고
    • Astrocytes, from brain glue to communication elements: The revolution continues
    • Volterra A, Meldolesi J. Astrocytes, from brain glue to communication elements: the revolution continues. Nature Rev 2005 6 : 626 640.
    • (2005) Nature Rev , vol.6 , pp. 626-640
    • Volterra, A.1    Meldolesi, J.2
  • 53
    • 31544456102 scopus 로고    scopus 로고
    • Astrocyte-mediated control of cerebral blood flow
    • Takano T, Tian GF, Peng W et al. Astrocyte-mediated control of cerebral blood flow. Nature neurosci 2006 9 : 260 267.
    • (2006) Nature Neurosci , vol.9 , pp. 260-267
    • Takano, T.1    Tian, G.F.2    Peng, W.3
  • 54
    • 33645004031 scopus 로고    scopus 로고
    • Glial cells dilate and constrict blood vessels: A mechanism of neurovascular coupling
    • Metea MR, Newman EA. Glial cells dilate and constrict blood vessels: a mechanism of neurovascular coupling. J Neurosci 2006 26 : 2862 2870.
    • (2006) J Neurosci , vol.26 , pp. 2862-2870
    • Metea, M.R.1    Newman, E.A.2
  • 55
    • 33745873475 scopus 로고    scopus 로고
    • Astrocyte control of synaptic transmission and neurovascular coupling
    • Haydon PG, Carmignoto G. Astrocyte control of synaptic transmission and neurovascular coupling. Physiol Rev 2006 86 : 1009 1031.
    • (2006) Physiol Rev , vol.86 , pp. 1009-1031
    • Haydon, P.G.1    Carmignoto, G.2
  • 56
    • 0031963859 scopus 로고    scopus 로고
    • Functional hyperemia in the brain: Hypothesis for astrocyte-derived vasodilator metabolites
    • Harder DR, Alkayed NJ, Lange AR et al. Functional hyperemia in the brain: hypothesis for astrocyte-derived vasodilator metabolites. Stroke 1998 29 : 229 234.
    • (1998) Stroke , vol.29 , pp. 229-234
    • Harder, D.R.1    Alkayed, N.J.2    Lange, A.R.3
  • 57
    • 0032171495 scopus 로고    scopus 로고
    • Intercellular calcium signaling and gap junctional communication in astrocytes
    • Giaume C, Venance L. Intercellular calcium signaling and gap junctional communication in astrocytes. Glia 1998 24 : 50 64.
    • (1998) Glia , vol.24 , pp. 50-64
    • Giaume, C.1    Venance, L.2
  • 58
    • 0032744492 scopus 로고    scopus 로고
    • Astrocyte-induced modulation of synaptic transmission
    • Araque A, Sanzgiri RP, Parpura V et al. Astrocyte-induced modulation of synaptic transmission. Can J Physiol Pharmacol 1999 77 : 699 706.
    • (1999) Can J Physiol Pharmacol , vol.77 , pp. 699-706
    • Araque, A.1    Sanzgiri, R.P.2    Parpura, V.3
  • 60
    • 0035047691 scopus 로고    scopus 로고
    • Dynamic signaling between astrocytes and neurons
    • Araque A, Carmignoto G, Haydon PG. Dynamic signaling between astrocytes and neurons. Ann Rev physiol 2001 63 : 795 813.
    • (2001) Ann Rev Physiol , vol.63 , pp. 795-813
    • Araque, A.1    Carmignoto, G.2    Haydon, P.G.3
  • 61
    • 0034743201 scopus 로고    scopus 로고
    • 2+ oscillations in situ drive NMDAR-mediated neuronal excitation
    • 2+ oscillations in situ drive NMDAR-mediated neuronal excitation. Nat Neurosci 2001 4 : 803 812.
    • (2001) Nat Neurosci , vol.4 , pp. 803-812
    • Parri, H.R.1    Gould, T.M.2    Crunelli, V.3
  • 62
    • 0031893563 scopus 로고    scopus 로고
    • Glial calcium: Homeostasis and signaling function
    • Verkhratsky A, Orkand RK, Kettenmann H. Glial calcium: homeostasis and signaling function. Physiol Rev 1998 78 : 99 141.
    • (1998) Physiol Rev , vol.78 , pp. 99-141
    • Verkhratsky, A.1    Orkand, R.K.2    Kettenmann, H.3
  • 63
    • 33644519960 scopus 로고    scopus 로고
    • Astrocyte dysfunction in neurological disorders: A molecular perspective
    • Seifert G, Schilling K, Steinhauser C. Astrocyte dysfunction in neurological disorders: a molecular perspective. Nat Rev Neurosci 2006 7 : 194 206.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 194-206
    • Seifert, G.1    Schilling, K.2    Steinhauser, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.