메뉴 건너뛰기




Volumn 5, Issue 1, 2012, Pages 1-11

Transgenic overexpression of keratinocyte-specific VEGF and Ang1 in combination promotes wound healing under nondiabetic but not diabetic conditions

Author keywords

Angiogenesis; Keratinocyte; Re epithelialization; Skin; Streptozotocin; Transgenic mouse; Wound healing

Indexed keywords

ANGIOPOIETIN 1; ANGPT1 PROTEIN, MOUSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

EID: 84856697787     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (51)
  • 1
    • 43449108812 scopus 로고    scopus 로고
    • Economic costs of diabetes in the US In 2007
    • American Diabetes Association
    • American Diabetes Association. Economic costs of diabetes in the US In 2007. Diabetes Care 2008; 31: 596-615.
    • (2008) Diabetes Care , vol.31 , pp. 596-615
  • 2
    • 0037372172 scopus 로고    scopus 로고
    • Abnormal angiogenesis in diabetes mellitus
    • Martin A, Komada MR and Sane DC. Abnormal angiogenesis in diabetes mellitus. Med Res Rev 2003; 23: 117-145.
    • (2003) Med Res Rev , vol.23 , pp. 117-145
    • Martin, A.1    Komada, M.R.2    Sane, D.C.3
  • 4
    • 0033894983 scopus 로고    scopus 로고
    • Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair
    • Wetzler C, Kampfer H, Stallmeyer B, Pfeilschifter J and Frank S. Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair. J Invest Dermatol 2000; 115: 245-253.
    • (2000) J Invest Dermatol , vol.115 , pp. 245-253
    • Wetzler, C.1    Kampfer, H.2    Stallmeyer, B.3    Pfeilschifter, J.4    Frank, S.5
  • 5
    • 54249117325 scopus 로고    scopus 로고
    • Hyperglycaemic conditions decrease cultured keratinocyte mobility: implications for impaired wound healing in patients with diabetes
    • Lan CC, Liu IH, Fang AH, Wen CH and Wu CS. Hyperglycaemic conditions decrease cultured keratinocyte mobility: implications for impaired wound healing in patients with diabetes. Br J Dermatol 2008; 159: 1103-1115.
    • (2008) Br J Dermatol , vol.159 , pp. 1103-1115
    • Lan, C.C.1    Liu, I.H.2    Fang, A.H.3    Wen, C.H.4    Wu, C.S.5
  • 6
    • 0035085050 scopus 로고    scopus 로고
    • Expressional regulation of angiopoietin-1 and -2 and the tie-1 and -2 receptor tyrosine kinases during cutaneous wound healing: a comparative study of normal and impaired repair
    • Kampfer H, Pfeilschifter J and Frank S. Expressional regulation of angiopoietin-1 and -2 and the tie-1 and -2 receptor tyrosine kinases during cutaneous wound healing: a comparative study of normal and impaired repair. Lab Invest 2001; 81: 361-373.
    • (2001) Lab Invest , vol.81 , pp. 361-373
    • Kampfer, H.1    Pfeilschifter, J.2    Frank, S.3
  • 7
    • 0029045246 scopus 로고
    • Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing
    • Frank S, Hubner G, Breier G, Longaker MT, Greenhalgh DG and Werner S. Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing. J Biol Chem 1995; 270: 12607-12613.
    • (1995) J Biol Chem , vol.270 , pp. 12607-12613
    • Frank, S.1    Hubner, G.2    Breier, G.3    Longaker, M.T.4    Greenhalgh, D.G.5    Werner, S.6
  • 10
    • 0030934532 scopus 로고    scopus 로고
    • Wound Healing-Aiming for Perfect Skin Regeneration
    • Martin P. Wound Healing-Aiming for Perfect Skin Regeneration. Science 1997; 276: 75-81.
    • (1997) Science , vol.276 , pp. 75-81
    • Martin, P.1
  • 12
    • 13844253297 scopus 로고    scopus 로고
    • In vivo gene delivery of Ad-VEGF to fullthickness wounds in aged pigs results in high levels of VEGF expression but not in accelerated healing
    • Vranckx JJ, Yao F, Petrie N, Augustinova H, Hoeller D, Visovatti S, Slama J and Eriksson E. In vivo gene delivery of Ad-VEGF to fullthickness wounds in aged pigs results in high levels of VEGF expression but not in accelerated healing. Wound Repair Regen 2005; 13: 51-60.
    • (2005) Wound Repair Regen , vol.13 , pp. 51-60
    • Vranckx, J.J.1    Yao, F.2    Petrie, N.3    Augustinova, H.4    Hoeller, D.5    Visovatti, S.6    Slama, J.7    Eriksson, E.8
  • 13
    • 0035063248 scopus 로고    scopus 로고
    • Systemically and topically supplemented leptin fails to reconstitute a normal angiogenic response during skin repair in diabetic ob/ob mice
    • Stallmeyer B, Pfeilschifter J and Frank S. Systemically and topically supplemented leptin fails to reconstitute a normal angiogenic response during skin repair in diabetic ob/ob mice. Diabetologia 2001; 44: 471-479.
    • (2001) Diabetologia , vol.44 , pp. 471-479
    • Stallmeyer, B.1    Pfeilschifter, J.2    Frank, S.3
  • 14
    • 0018571270 scopus 로고
    • Adult microvascular disturbances as a result of juvenile onset diabetes in Db/Db mice
    • Bohlen HG, Niggl BA. Adult microvascular disturbances as a result of juvenile onset diabetes in Db/Db mice. Blood Vessels 1979; 16: 269-276.
    • (1979) Blood Vessels , vol.16 , pp. 269-276
    • Bohlen, H.G.1    Niggl, B.A.2
  • 15
    • 0025359279 scopus 로고
    • PDGF and FGF stimulate wound healing in the genetically diabetic mouse
    • Greenhalgh DG, Sprugel KH, Murray MJ and Ross R. PDGF and FGF stimulate wound healing in the genetically diabetic mouse. Am J Pathol 1990; 136: 1235-1246.
    • (1990) Am J Pathol , vol.136 , pp. 1235-1246
    • Greenhalgh, D.G.1    Sprugel, K.H.2    Murray, M.J.3    Ross, R.4
  • 17
    • 2442717879 scopus 로고    scopus 로고
    • Topical Vascular Endothelial Growth Factor Accelerates Diabetic Wound Healing through Increased Angiogenesis and by Mobilizing and Recruiting Bone Marrow-Derived Cells
    • Galiano RD, Tepper OM, Pelo CR, Bhatt KA, Callaghan M, Bastidas N, Bunting S, Steinmetz HG and Gurtner GC. Topical Vascular Endothelial Growth Factor Accelerates Diabetic Wound Healing through Increased Angiogenesis and by Mobilizing and Recruiting Bone Marrow-Derived Cells. Am J Pathol 2004; 164: 1935-1947.
    • (2004) Am J Pathol , vol.164 , pp. 1935-1947
    • Galiano, R.D.1    Tepper, O.M.2    Pelo, C.R.3    Bhatt, K.A.4    Callaghan, M.5    Bastidas, N.6    Bunting, S.7    Steinmetz, H.G.8    Gurtner, G.C.9
  • 18
    • 0036422555 scopus 로고    scopus 로고
    • Differential expression of matrix metalloproteinases during impaired wound healing of the diabetes mouse
    • Wall SJ, Bevan D, Thomas DW, Harding KG, Edwards DR and Murphy G. Differential expression of matrix metalloproteinases during impaired wound healing of the diabetes mouse. J Invest Dermatol 2002; 119: 91-98.
    • (2002) J Invest Dermatol , vol.119 , pp. 91-98
    • Wall, S.J.1    Bevan, D.2    Thomas, D.W.3    Harding, K.G.4    Edwards, D.R.5    Murphy, G.6
  • 20
    • 0037184495 scopus 로고    scopus 로고
    • Molecular understanding of hyperglycemia's adverse effects for diabetic complications
    • Sheetz MJ, King GL. Molecular understanding of hyperglycemia's adverse effects for diabetic complications. Jama 2002; 288: 2579-2588.
    • (2002) Jama , vol.288 , pp. 2579-2588
    • Sheetz, M.J.1    King, G.L.2
  • 21
    • 0026756163 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing
    • Brown LF, Yeo KT, Berse B, Yeo TK, Senger DR, Dvorak HF and van de Water L. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J Exp Med 1992; 176: 1375-1379.
    • (1992) J Exp Med , vol.176 , pp. 1375-1379
    • Brown, L.F.1    Yeo, K.T.2    Berse, B.3    Yeo, T.K.4    Senger, D.R.5    Dvorak, H.F.6    van de Water, L.7
  • 23
    • 0033057591 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is more important than basic fibroblastic growth factor during ischemic wound healing
    • Corral CJ, Siddiqui A, Wu L, Farrell CL, Lyons D and Mustoe TA. Vascular endothelial growth factor is more important than basic fibroblastic growth factor during ischemic wound healing. Arch Surg 1999; 134: 200-205.
    • (1999) Arch Surg , vol.134 , pp. 200-205
    • Corral, C.J.1    Siddiqui, A.2    Wu, L.3    Farrell, C.L.4    Lyons, D.5    Mustoe, T.A.6
  • 24
    • 0038293298 scopus 로고    scopus 로고
    • Adeno-associated viral vectormediated human vascular endothelial growth factor gene transfer stimulates angiogenesis and wound healing in the genetically diabetic mouse
    • Galeano M, Deodato B, Altavilla D, Cucinotta D, Arsic N, Marini H, Torre V, Giacca M and Squadrito F. Adeno-associated viral vectormediated human vascular endothelial growth factor gene transfer stimulates angiogenesis and wound healing in the genetically diabetic mouse. Diabetologia 2003; 46: 546-555.
    • (2003) Diabetologia , vol.46 , pp. 546-555
    • Galeano, M.1    Deodato, B.2    Altavilla, D.3    Cucinotta, D.4    Arsic, N.5    Marini, H.6    Torre, V.7    Giacca, M.8    Squadrito, F.9
  • 25
    • 9444299031 scopus 로고    scopus 로고
    • Plasma Vascular Endothelial Growth Factor, Angiopoietin-1, and Angiopoietin-2 in Diabetes: Implications for cardiovascular risk and effects of multifactorial intervention
    • Lim HS, Blann AD, Chong AY, Freestone B and Lip GYH. Plasma Vascular Endothelial Growth Factor, Angiopoietin-1, and Angiopoietin-2 in Diabetes: Implications for cardiovascular risk and effects of multifactorial intervention Diabetes Care 2004; 27: 2918-2924.
    • (2004) Diabetes Care , vol.27 , pp. 2918-2924
    • Lim, H.S.1    Blann, A.D.2    Chong, A.Y.3    Freestone, B.4    Lip, G.Y.H.5
  • 27
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan D. Signaling vascular morphogenesis and maintenance. Science 1997; 277: 48-50.
    • (1997) Science , vol.277 , pp. 48-50
    • Hanahan, D.1
  • 29
    • 0036707853 scopus 로고    scopus 로고
    • Angiopoietin-2 and rat brain capillary remodeling during adaptation and deadaptation to prolonged mild hypoxia
    • Pichiule P, LaManna JC. Angiopoietin-2 and rat brain capillary remodeling during adaptation and deadaptation to prolonged mild hypoxia. Journal of Applied Physiology 2002; 93: 1131-1139.
    • (2002) Journal of Applied Physiology , vol.93 , pp. 1131-1139
    • Pichiule, P.1    LaManna, J.C.2
  • 30
    • 0032693760 scopus 로고    scopus 로고
    • Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development
    • Puri MC, Partanen J, Rossant J and Bernstein A. Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development. Development 1999; 126: 4569-4580.
    • (1999) Development , vol.126 , pp. 4569-4580
    • Puri, M.C.1    Partanen, J.2    Rossant, J.3    Bernstein, A.4
  • 31
    • 0034984712 scopus 로고    scopus 로고
    • Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function
    • Jones N, Voskas D, Master Z, Sarao R, Jones J and Dumont DJ. Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function. EMBO Rep 2001; 2: 438-445.
    • (2001) EMBO Rep , vol.2 , pp. 438-445
    • Jones, N.1    Voskas, D.2    Master, Z.3    Sarao, R.4    Jones, J.5    Dumont, D.J.6
  • 34
    • 0036318855 scopus 로고    scopus 로고
    • Complementary actions of VEGF and angiopoietin-1 on blood vessel growth and leakage
    • Thurston G. Complementary actions of VEGF and angiopoietin-1 on blood vessel growth and leakage. Journal of anatomy 2002; 200: 575-580.
    • (2002) Journal of anatomy , vol.200 , pp. 575-580
    • Thurston, G.1
  • 39
    • 33645508703 scopus 로고    scopus 로고
    • COMPangiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model
    • Cho CH, Sung HK, Kim KT, Cheon HG, Oh GT, Hong HJ, Yoo OJ and Koh GY. COMPangiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proc Natl Acad Sci USA 2006; 103: 4946-4951.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 4946-4951
    • Cho, C.H.1    Sung, H.K.2    Kim, K.T.3    Cheon, H.G.4    Oh, G.T.5    Hong, H.J.6    Yoo, O.J.7    Koh, G.Y.8
  • 41
    • 78650679600 scopus 로고    scopus 로고
    • Cutaneous manipulation of vascular growth factors leads to alterations in immunocytes, blood vessels and nerves: Evidence for a cutaneous neurovascular unit
    • Ward NL, Hatala DA, Wolfram JA, Knutsen DA and Loyd CM. Cutaneous manipulation of vascular growth factors leads to alterations in immunocytes, blood vessels and nerves: Evidence for a cutaneous neurovascular unit. Journal of Dermatological Science 2011; 61: 14-22.
    • (2011) Journal of Dermatological Science , vol.61 , pp. 14-22
    • Ward, N.L.1    Hatala, D.A.2    Wolfram, J.A.3    Knutsen, D.A.4    Loyd, C.M.5
  • 45
    • 4544331876 scopus 로고    scopus 로고
    • Functional inhibition of secreted angiopoietin: a novel role for angiopoietin 1 in coronary vessel patterning
    • Ward NL, Slyke PV and Dumont DJ. Functional inhibition of secreted angiopoietin: a novel role for angiopoietin 1 in coronary vessel patterning. Biochemical and Biophysical Research Communications 2004; 323: 937-946.
    • (2004) Biochemical and Biophysical Research Communications , vol.323 , pp. 937-946
    • Ward, N.L.1    Slyke, P.V.2    Dumont, D.J.3
  • 46
    • 67349083966 scopus 로고    scopus 로고
    • Angiopoietin-1 induces neurite outgrowth of PC12 cells in a Tie2-independent, beta1-integrindependent manner
    • Chen X, Fu W, Tung CE and Ward NL. Angiopoietin-1 induces neurite outgrowth of PC12 cells in a Tie2-independent, beta1-integrindependent manner. Neurosci Res 2009; 64: 348-354.
    • (2009) Neurosci Res , vol.64 , pp. 348-354
    • Chen, X.1    Fu, W.2    Tung, C.E.3    Ward, N.L.4
  • 47
    • 77951091422 scopus 로고    scopus 로고
    • Angiopoietin-1 Reduces H2O2-Induced Increases in Reactive Oxygen Species and Oxidative Damage to Skin Cells
    • Ismail NS, Pravda EA, Li D, Shih SC and Dallabrida SM. Angiopoietin-1 Reduces H2O2-Induced Increases in Reactive Oxygen Species and Oxidative Damage to Skin Cells. J Invest Dermatol 2010; 130: 1307-1317.
    • (2010) J Invest Dermatol , vol.130 , pp. 1307-1317
    • Ismail, N.S.1    Pravda, E.A.2    Li, D.3    Shih, S.C.4    Dallabrida, S.M.5
  • 50
    • 79955136974 scopus 로고    scopus 로고
    • Vascular Endothelial Growth Factor Receptor-2 Couples Cyclo-Oxygenase-2 with Pro-Angiogenic Actions of Leptin on Human Endothelial Cells
    • Garonna E, Botham KM, Birdsey GM, Randi AM, Gonzalez-Perez RR and Wheeler-Jones CPD. Vascular Endothelial Growth Factor Receptor-2 Couples Cyclo-Oxygenase-2 with Pro-Angiogenic Actions of Leptin on Human Endothelial Cells. PLoS ONE 2011; 6: e18823.
    • (2011) PLoS ONE , vol.6
    • Garonna, E.1    Botham, K.M.2    Birdsey, G.M.3    Randi, A.M.4    Gonzalez-Perez, R.R.5    Wheeler-Jones, C.P.D.6
  • 51
    • 34848851922 scopus 로고    scopus 로고
    • Angiogenesis modulates adipogenesis and obesity
    • Cao Y. Angiogenesis modulates adipogenesis and obesity. The Journal of Clinical Investigation 2007; 117: 2362-2368.
    • (2007) The Journal of Clinical Investigation , vol.117 , pp. 2362-2368
    • Cao, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.