메뉴 건너뛰기




Volumn 9, Issue 19, 2002, Pages 1271-1277

Adenovirus-mediated VEGF165 gene transfer enhances wound healing by promoting angiogenesis in CD1 diabetic mice

Author keywords

Diabetes; Gene therapy; VEGF; Wound healing

Indexed keywords

ADENOVIRUS VECTOR; ANESTHETIC AGENT; BETA LACTAMASE; BROMETHOL; GROWTH FACTOR; SODIUM CHLORIDE; STREPTOZOCIN; VASCULOTROPIN; WOUND HEALING PROMOTING AGENT;

EID: 0036792590     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301798     Document Type: Article
Times cited : (112)

References (46)
  • 1
    • 0027430742 scopus 로고
    • Biology of dermal wound repair
    • Clark RAF. Biology of dermal wound repair. Dermatol Clin 1993; 11: 647-666.
    • (1993) Dermatol. Clin , vol.11 , pp. 647-666
    • Clark, R.A.F.1
  • 2
    • 0020331685 scopus 로고
    • Angiogenesis: Initiation and control
    • Folkman J. Angiogenesis: initiation and control. Ann NY Acad Sci 1982; 401: 212-227.
    • (1982) Ann. NY. Acad. Sci , vol.401 , pp. 212-227
    • Folkman, J.1
  • 3
    • 0035062394 scopus 로고    scopus 로고
    • The splice variants of vascular endothelial growth factor (VEGF) and their receptors
    • Robinson CJ et al. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J Cell Sci 2001; 5: 853-865.
    • (2001) J. Cell Sci , vol.5 , pp. 853-865
    • Robinson, C.J.1
  • 4
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW et al. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989; 246: 1306-1309.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1
  • 5
    • 0024801035 scopus 로고
    • Vascular permeability factor, an endothelial cell mitogen related to PDGF
    • Keck PJ et al. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 1989; 8: (246) 1309-1312.
    • (1989) Science , vol.8 , Issue.246 , pp. 1309-1312
    • Keck, P.J.1
  • 6
    • 0033616130 scopus 로고    scopus 로고
    • Angiogenesis: How a tumor adapts to hypoxia
    • Richard DE et al. Angiogenesis: how a tumor adapts to hypoxia. Biochem Biophys Res Commun 1999; 266: 718-722.
    • (1999) Biochem. Biophys. Res. Commun , vol.266 , pp. 718-722
    • Richard, D.E.1
  • 7
    • 0031779927 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing
    • Nissen N et al. Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing. Am J Pathol 1998; 152: 1445-1452.
    • (1998) Am. J. Pathol , vol.152 , pp. 1445-1452
    • Nissen, N.1
  • 8
    • 0027980960 scopus 로고
    • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
    • Detmar M et al. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med 1994; 180: 1141-1146.
    • (1994) J. Exp. Med , vol.180 , pp. 1141-1146
    • Detmar, M.1
  • 9
    • 0029129814 scopus 로고
    • Keratinocyte-derived vascular permeability factor (vascular endothelial growth factor) is a potent mitogen for dermal microvascular endothelial cells
    • Detmar M et al. Keratinocyte-derived vascular permeability factor (vascular endothelial growth factor) is a potent mitogen for dermal microvascular endothelial cells. J Invest Dermatol 1995; 105: 44-50.
    • (1995) J. Invest. Dermatol , vol.105 , pp. 44-50
    • Detmar, M.1
  • 10
    • 0028798060 scopus 로고
    • Human keratinocytes express the three major splice forms of vascular endothelial growth factor
    • Ballaun C et al. Human keratinocytes express the three major splice forms of vascular endothelial growth factor. J Invest Dermatol 1995; 104: 7-10.
    • (1995) J. Invest. Dermatol , vol.104 , pp. 7-10
    • Ballaun, C.1
  • 11
    • 0029045246 scopus 로고
    • Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing
    • Frank S et al. Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing. J Biol Chem 1995; 270: 12607-12613.
    • (1995) J. Biol. Chem , vol.270 , pp. 12607-12613
    • Frank, S.1
  • 12
    • 0029993352 scopus 로고    scopus 로고
    • Molecular regulation of angiogenesis in the skin
    • Detmar M. Molecular regulation of angiogenesis in the skin. J Invest Dermatol 1996; 106: 207-208.
    • (1996) J. Invest. Dermatol , vol.106 , pp. 207-208
    • Detmar, M.1
  • 13
    • 7144264398 scopus 로고    scopus 로고
    • Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice
    • Detmar M et al. Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. J Invest Dermatol 1998; 111: 1-6.
    • (1998) J. Invest. Dermatol , vol.111 , pp. 1-6
    • Detmar, M.1
  • 14
    • 0033883530 scopus 로고    scopus 로고
    • In vivo detection of human vascular endothelial growth factor promoter activity in transgenic mouse skin
    • Kishimoto J et al. In vivo detection of human vascular endothelial growth factor promoter activity in transgenic mouse skin. Am J Pathol 2000; 157: 103-110.
    • (2000) Am. J. Pathol , vol.157 , pp. 103-110
    • Kishimoto, J.1
  • 15
    • 0032472835 scopus 로고    scopus 로고
    • Role of nerve growth factor in cutaneous wound healing: Accelerating effects in normal and healing-impaired diabetic mice
    • Matsuda H et al. Role of nerve growth factor in cutaneous wound healing: accelerating effects in normal and healing-impaired diabetic mice. J Exp Med 1998; 187: 297-306.
    • (1998) J. Exp. Med , vol.187 , pp. 297-306
    • Matsuda, H.1
  • 16
    • 0031908209 scopus 로고    scopus 로고
    • Glucocorticoid dynamics and impaired wound healing in diabetes mellitus
    • Bitar MS. Glucocorticoid dynamics and impaired wound healing in diabetes mellitus. Am J Pathol 1998; 152: 547-554.
    • (1998) Am. J. Pathol , vol.152 , pp. 547-554
    • Bitar, M.S.1
  • 17
    • 0030953388 scopus 로고    scopus 로고
    • Differential expression and localization of insulin-like growth factors I and II in cutaneous wounds of diabetic and nondiabetic mice
    • Brown DL et al. Differential expression and localization of insulin-like growth factors I and II in cutaneous wounds of diabetic and nondiabetic mice. Am J Pathol 1997; 151: 715-724.
    • (1997) Am. J. Pathol , vol.151 , pp. 715-724
    • Brown, D.L.1
  • 18
    • 0026718123 scopus 로고
    • Human gene therapy comes of age
    • Miller AD. Human gene therapy comes of age. Nature 1992; 357: 455-460.
    • (1992) Nature , vol.357 , pp. 455-460
    • Miller, A.D.1
  • 19
    • 0027595949 scopus 로고
    • The basic science of gene therapy
    • Mulligan RC. The basic science of gene therapy. Science 1993; 260: 926-932.
    • (1993) Science , vol.260 , pp. 926-932
    • Mulligan, R.C.1
  • 20
    • 0027477148 scopus 로고
    • Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors
    • Bajocchi G et al. Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nat Genet 1993; 3: 229-234.
    • (1993) Nat. Genet , vol.3 , pp. 229-234
    • Bajocchi, G.1
  • 21
    • 0028281972 scopus 로고
    • Ex vivo and in vivo gene transfer to the skin using replication-deficient recombinant adenovirus vectors
    • Setoguchi Y et al. Ex vivo and in vivo gene transfer to the skin using replication-deficient recombinant adenovirus vectors. J Invest Dermatol 1994; 102: 415-421.
    • (1994) J. Invest. Dermatol , vol.102 , pp. 415-421
    • Setoguchi, Y.1
  • 22
    • 0033744749 scopus 로고    scopus 로고
    • The diabetic foot: A global view
    • Boulton AJ. The diabetic foot: a global view. Diabet Metab Res Rev 2000; 16 (Suppl. 1): S2-S5.
    • (2000) Diabet. Metab. Res Rev , vol.16 , pp. S2-S5
    • Boulton, A.J.1
  • 23
    • 0035487693 scopus 로고    scopus 로고
    • Early detection of microcirculatory impairment in diabetic patients with foot at risk
    • Zimny S et al. Early detection of microcirculatory impairment in diabetic patients with foot at risk. Diabetes Care 2001; 24: 1810-1814.
    • (2001) Diabetes Care , vol.24 , pp. 1810-1814
    • Zimny, S.1
  • 24
    • 0035041407 scopus 로고    scopus 로고
    • Cellular and molecular pathogenic mechanisms of insulin-dependent diabetes mellitus
    • Woon Ji-Won. Cellular and molecular pathogenic mechanisms of insulin-dependent diabetes mellitus. Ann NY Acad Sci 2001; 928: 200-211.
    • (2001) Ann. NY. Acad. Sci , vol.928 , pp. 200-211
    • Woon, J.-W.1
  • 25
    • 0032965317 scopus 로고    scopus 로고
    • Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF
    • Rivard A et al. Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. Am J Pathol 1999; 154: 355-363.
    • (1999) Am. J. Pathol , vol.154 , pp. 355-363
    • Rivard, A.1
  • 26
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes- obesity syndrome in mice
    • Coleman DL et al. Obese and diabetes: two mutant genes causing diabetes- obesity syndrome in mice. Diabetologia 1978; 14: 141-148.
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 27
    • 0026751184 scopus 로고
    • Partial protection of 1 alpha-hydroxyvitamin D3 against the development of diabetes induced by multiple low-dose streptozotocin injection in CD-1 mice
    • Inaba M et al. Partial protection of 1 alpha-hydroxyvitamin D3 against the development of diabetes induced by multiple low-dose streptozotocin injection in CD-1 mice. Metabolism 1992; 41: 631-635.
    • (1992) Metabolism , vol.41 , pp. 631-635
    • Inaba, M.1
  • 28
    • 0033057591 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is more important than basic fibroblastic growth factor during ischemic wound healing
    • Corral CJ et al. Vascular endothelial growth factor is more important than basic fibroblastic growth factor during ischemic wound healing. Arch Surg 1999; 134: 200-205.
    • (1999) Arch. Surg , vol.134 , pp. 200-205
    • Corral, C.J.1
  • 29
    • 0023628856 scopus 로고
    • High glucose prolongs cell-cycle traversal of cultured human endothelial cells
    • Lorenzi M et al. High glucose prolongs cell-cycle traversal of cultured human endothelial cells. Diabetes 1987; 36: 1261-1267.
    • (1987) Diabetes , vol.36 , pp. 1261-1267
    • Lorenzi, M.1
  • 30
    • 0027054448 scopus 로고
    • Decreased cultured endothelial cell proliferation in high glucose medium is reversed by antioxidants: New insights on the pathophysiological mechanisms of diabetic vascular complications
    • Curcio F et al. Decreased cultured endothelial cell proliferation in high glucose medium is reversed by antioxidants: new insights on the pathophysiological mechanisms of diabetic vascular complications. In Vitro Cell Dev Biol 1992; 28: 787-790.
    • (1992) Vitro Cell Dev. Biol , vol.28 , pp. 787-790
    • Curcio, F.1
  • 31
    • 0026756163 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing
    • Brown LF et al. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J Exp Med 1992; 176: 1375-1379.
    • (1992) J. Exp. Med , vol.176 , pp. 1375-1379
    • Brown, L.F.1
  • 32
    • 0027424647 scopus 로고
    • Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth
    • Peters KG et al. Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth. Proc Natl Acad Sci USA 1993; 90: 8915-8919.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8915-8919
    • Peters, K.G.1
  • 33
    • 0025359279 scopus 로고
    • PDGF and FGF stimulate wound healing in the genetically diabetic mice
    • Greenhalgh DG et al. PDGF and FGF stimulate wound healing in the genetically diabetic mice. Am J Pathol 1990; 136: 1235-1246.
    • (1990) Am. J. Pathol , vol.136 , pp. 1235-1246
    • Greenhalgh, D.G.1
  • 34
    • 0026786815 scopus 로고
    • The safety and effect of topically applied recombinant basic fibroblast growth factor on the healing of chronic pressure sores
    • Robson MC et al. The safety and effect of topically applied recombinant basic fibroblast growth factor on the healing of chronic pressure sores. Ann Surg 1992; 216: 401-406.
    • (1992) Ann. Surg , vol.216 , pp. 401-406
    • Robson, M.C.1
  • 35
    • 0342871993 scopus 로고    scopus 로고
    • Double-blind randomized placebo-controlled trial of the use of granulocyte-macrophage colony-stimulating factor in chronic leg ulcers
    • Marques da Costa R. Double-blind randomized placebo-controlled trial of the use of granulocyte-macrophage colony-stimulating factor in chronic leg ulcers. Am J Surg 1997; 173: 165-168.
    • (1997) Am. J. Surg , vol.173 , pp. 165-168
    • Marques da Costa, R.1
  • 36
    • 0032713818 scopus 로고    scopus 로고
    • Adenovirus-mediated acidic fibroblast growth factor gene transfer induces angiogenesis in the nonischemic rabbit heart
    • Safi Jr J et al. Adenovirus-mediated acidic fibroblast growth factor gene transfer induces angiogenesis in the nonischemic rabbit heart. Microvasc Res 1999; 58: 238-249.
    • (1999) Microvasc. Res , vol.58 , pp. 238-249
    • Safi, J.1
  • 37
    • 0033520056 scopus 로고    scopus 로고
    • Angiogenesis gene therapy: Phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease
    • Rosengart TK et al. Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation 1999; 100: 468-474.
    • (1999) Circulation , vol.100 , pp. 468-474
    • Rosengart, T.K.1
  • 38
    • 0031043724 scopus 로고    scopus 로고
    • Transfection with aFGF cDNA improves wound healing
    • Sun L et al. Transfection with aFGF cDNA improves wound healing. J Invest Dermatol 1997; 108: 313-318.
    • (1997) J. Invest. Dermatol , vol.108 , pp. 313-318
    • Sun, L.1
  • 39
    • 0032031678 scopus 로고    scopus 로고
    • Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer
    • Yamasaki K et al. Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer. J Clin Invest 1998; 101: 967-971.
    • (1998) J. Clin. Invest , vol.101 , pp. 967-971
    • Yamasaki, K.1
  • 40
    • 0032836753 scopus 로고    scopus 로고
    • Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing
    • Liechty KW et al. Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing. J Invest Dermatol 1999; 113: 375-383.
    • (1999) J. Invest. Dermatol , vol.113 , pp. 375-383
    • Liechty, K.W.1
  • 41
    • 0034730094 scopus 로고    scopus 로고
    • Left ventricular electromechanical mapping to asses efficacy of phVEGF (165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia
    • Vale PR et al. Left ventricular electromechanical mapping to asses efficacy of phVEGF (165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia. Circulation 2000; 102: 965-974.
    • (2000) Circulation , vol.102 , pp. 965-974
    • Vale, P.R.1
  • 42
    • 0034021278 scopus 로고    scopus 로고
    • Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer
    • Leek RD et al. Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. J Pathol 2000; 190: 430-436.
    • (2000) J. Pathol , vol.190 , pp. 430-436
    • Leek, R.D.1
  • 43
    • 0028971501 scopus 로고
    • VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo
    • Muhlhauser J et al. VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo. Circ Res 1995; 77: 1077-1086.
    • (1995) Circ. Res , vol.77 , pp. 1077-1086
    • Muhlhauser, J.1
  • 44
    • 0023682087 scopus 로고
    • Effects of cyclosporin on autoimmune diabetes induced in mice by streptozotocin: Beta cell-toxicity and rebound of insulitis after cessation of treatment
    • Sai P et al. Effects of cyclosporin on autoimmune diabetes induced in mice by streptozotocin: beta cell-toxicity and rebound of insulitis after cessation of treatment. Diabet Metab 1988; 14: 455-462.
    • (1988) Diabet. Metab , vol.14 , pp. 455-462
    • Sai, P.1
  • 45
    • 0034255465 scopus 로고    scopus 로고
    • Adenovirus-mediated VEGF(121) gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia
    • Gowdak LH et al. Adenovirus-mediated VEGF(121) gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia. Circulation 2000; 102: 565-571.
    • (2000) Circulation , vol.102 , pp. 565-571
    • Gowdak, L.H.1
  • 46
    • 0025764203 scopus 로고
    • Loss of intermediate-sized coronary arteries and capillary proliferation after left ventricular failure in rats
    • Anversa P, Capasso JM. Loss of intermediate-sized coronary arteries and capillary proliferation after left ventricular failure in rats. Am J Physiol 1991; 260: H1552-Hl560.
    • (1991) Am. J. Physiol , vol.260 , pp. H1552-Hl560
    • Anversa, P.1    Capasso, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.