Angiopoietin-1 reduces H2O2-induced increases in reactive oxygen species and oxidative damage to skin cells

Journal of Investigative Dermatology

Volumn 130, Issue 5, 2010, Pages 1307-1317

  Ismail, Nesreen S ^a   Pravda, Elke A ^a   Li, Dan ^b   Shih, Shou Ching ^b,c   Dallabrida, Susan M ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYDEOXYGUANOSINE; ALPHA2 INTEGRIN; ALPHA3 INTEGRIN; ALPHA6 INTEGRIN; ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; ANTIBODY; BETA1 INTEGRIN; BETA3 INTEGRIN; BETA4 INTEGRIN; BETA6 INTEGRIN; CD51 ANTIGEN; DNA; FREE RADICAL; HYDROGEN PEROXIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ARTICLE; CELL ADHESION; CELL DAMAGE; CELL DISRUPTION; CELL LINE; CELL METABOLISM; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; KERATINOCYTE; MELANOCYTE; MULTIGENE FAMILY; OXIDATIVE STRESS; PHOTOAGING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN CANCER; SKIN CELL;

EID: 77951091422     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2009.431     Document Type: Article

References (74)

1. Ahmed NU, Ueda M, Nikaido O et al. (1999) High levels of 8-hydroxy-2-deoxyguanosine appear in normal human epidermis after a single dose of ultraviolet radiation. Br J Dermatol 140:226-231
2. Aitken GR, Henderson JR, Chang SC et al. (2007) Direct monitoring of UV-induced free radical generation in HaCaT keratinocytes. Clin Exp Dermatol 32:722-727
3. Baffert F, Le T, Thurston G et al. (2006) Angiopoietin-1 decreases plasma leakage by reducing number and size of endothelial gaps in venules. Am J Physiol Heart Circ Physiol 290:H107-18
4. Bitto A, Minutoli L, Galeano MR et al. (2008) Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression. Clin Sci (Lond) 114:707-718
5. Black HS (1987) Potential involvement of free radical reactions in ultraviolet light-mediated cutaneous damage. Photochem Photobiol 46:213-221
6. Brown GC, Borutaite V (2001) Nitric oxide, mitochondria, and cell death. IUBMB Life 52:189-195
7. Cadet J, Douki T, Pouget JP et al. (2000) Singlet oxygen DNA damage products: formation and measurement. Methods Enzymol 319:143-153
8. Cao C, Lu S, Kivlin R et al. (2008) AMP-activated protein kinase contributes to UV-and H2O2-induced apoptosis in human skin keratinocytes. J Biol Chem 283:28897-28908
9. Carlson TR, Feng Y, Maisonpierre PC et al. (2001) Direct cell adhesion to the angiopoietins mediated by integrins. J Biol Chem 276:26516-26525
10. Cassina AM, Hodara R, Souza JM et al. (2000) Cytochrome c nitration by peroxynitrite. J Biol Chem 275:21409-21415
11. Cerutti PA (1985) Prooxidant states and tumor promotion. Science 227:375-381
12. Chen X, Abair TD, Ibanez MR et al. (2007) Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated rac activation. Mol Cell Biol 27:3313-3326
13. Chen X, Fu W, Tung CE et al. (2009) Angiopoietin-1 induces neurite outgrowth of PC12 cells in a tie2-independent, beta1-integrin-dependent manner. Neurosci Res 64:348
14. Chen X, Moeckel G, Morrow JD et al. (2004) Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury. Am J Pathol 165:617-630
15. Cho CH, Sung HK, Kim KT et al. (2006) COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proc Natl Acad Sci USA 103:4946-4951
16. Dallabrida SM, Ismail N, Oberle JR et al. (2005) Angiopoietin-1 promotes cardiac and skeletal myocyte survival through integrins. Circ Res 96:e8-24
17. Dallabrida SM, Ismail NS, Pravda EA et al. (2008) Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy. FASEB J 22:3010-3023
18. Decraene D, Agostinis P, Bouillon R et al. (2002) Insulin-like growth factor-1-mediated akt activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes. J Biol Chem 277:32587-32595
19. Duthie MS, Kimber I, Norval M (1999) The effects of ultraviolet radiation on the human immune system. Br J Dermatol 140:995-1009
20. Eun Kim K, Cho C-H, Kim H-Z et al. (2007) In vivo actions of angiopoietins on quiescent and remodeling blood and lymphatic vessels in mouse airways and skin. Arterioscler Thromb Vasc Biol 27:564-570
21. Feig DI, Reid TM, Loeb LA (1994) Reactive oxygen species in tumorigenesis. Cancer Res 54:1890s-4s
22. Gailit J, Colflesh D, Rabiner I et al. (1993) Redistribution and dysfunction of integrins in cultured renal epithelial cells exposed to oxidative stress. Am J Physiol 264:F149-57
23. Gilchrest BA, Eller MS, Geller AC et al. (1999) The pathogenesis of melanoma induced by ultraviolet radiation. N Engl J Med 340:1341-1348
24. Gloster HM Jr, Brodland DG (1996) The epidemiology of skin cancer. Dermatol Surg 22:217-226
25. Hawighorst T, Skobe M, Streit M et al. (2002) Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth. Am J Pathol 160:1381-1392
26. Helfrich I, Edler L, Sucker A et al. (2009) Angiopoietin-2 levels are associated with disease progression in metastatic malignant melanoma. Clin Cancer Res 15:1384-1392
27. Hu B, Jarzynka MJ, Guo P et al. (2006) Angiopoietin-2 induces glioma cell invasion by stimulating matrix metalloprotease-2 expression through the alphaVbeta1 integrin and focal adhesion kinase signaling pathway. Cancer Res 66:775-783
28. Imanishi Y, Hu B, Jarzynka MJ et al. (2007) Angiopoietin-2 stimulates breast cancer metastasis through the alpha5beta1 integrin-mediated pathway. Cancer Res 67:4254-4263
29. Jung H, Gurunluoglu R, Scharpf J et al. (2003) Adenovirus-mediated angiopoietin-1 gene therapy enhances skin flap survival. Microsurgery 23:374-380
30. Kagan VE, Kisin ER, Kawai K et al. (2002) Toward mechanism-based antioxidant interventions: lessons from natural antioxidants. Ann N Y Acad Sci 959:188-198
31. Kasai H, Nishimura S (1986) Hydroxylation of guanine in nucleosides and DNA at the C-8 position by heated glucose and oxygen radical-forming agents. Environ Health Perspect 67:111-116
32. Kim SR, Lee KS, Park SJ et al. (2008) Angiopoietin-1 variant, COMP-ang1 attenuates hydrogen peroxide-induced acute lung injury. Exp Mol Med 40:320-331
33. Krishna CM, Liebmann JE, Kaufman D et al. (1992) The catecholic metal sequestering agent 1,2-dihydroxybenzene-3,5-disulfonate confers protection against oxidative cell damage. Arch Biochem Biophys 294:98-106
34. Lovell CR, Smolenski KA, Duance VC et al. (1987) Type I and III collagen content and fibre distribution in normal human skin during ageing. Br J Dermatol 117:419-428
35. Makrantonaki ECC (2007) Molecular mechanisms of skin aging. Ann NY Acad Sci 1119:40-50
36. Muller FL, Lustgarten MS, Jang Y et al. (2007) Trends in oxidative aging theories. Free Radic Biol Med 43:477-503
37. Murakami T, Takagi H, Suzuma K et al. (2005) Angiopoietin-1 attenuates H2O2-induced sek1/jnk phosphorylation through the phosphatidylino-sitol 3-kinase/akt pathway in vascular endothelial cells. J Biol Chem 280:31841-31849
38. Muthusamy V, Piva TJ (2009) The UV response of the skin: a review of the MAPK, NFkappaB and TNFalpha signal transduction pathways. Arch Dermatol Res 302:5-17
39. Nachbar F, Korting HC (1995) The role of vitamin E in normal and damaged skin. J Mol Med 73:7-17
40. Nataraj AJ, Trent JC II, Ananthaswamy HN (1995) p53 gene mutations and photocarcinogenesis. Photochem Photobiol 62:218-230
41. Oberley TD (2002) Oxidative damage and cancer. Am J Pathol 160:403-408
42. Oike Y, Yasunaga K, Ito Y et al. (2003) Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration. PNAS 100:9494-9499
43. Olinski R, Zastawny T, Budzbon J et al. (1992) DNA base modifications in chromatin of human cancerous tissues. FEBS Lett 309:193-198
44. Ozawa T (1997) Genetic and functional changes in mitochondria associated with aging. Physiol Rev 77:425-464
45. Papapetropoulos A, Garcia-Cardena G, Dengler TJ et al. (1999) Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors. Lab Invest 79:213-223
46. Paz ML, Gonzalez Maglio DH, Weill FS et al. (2008) Mitochondrial dysfunction and cellular stress progression after ultraviolet B irradiation in human keratinocytes. Photodermatol Photoimmunol Photomed 24:115-122
47. Pelle E, Huang X, Mammone T et al. (2003) Ultraviolet-B-induced oxidative DNA base damage in primary normal human epidermal keratinocytes and inhibition by a hydroxyl radical scavenger. J Invest Dermatol 121:177-183
48. Plow EF, Haas TA, Zhang L et al. (2000) Ligand binding to integrins. J Biol Chem 275:21785-21788
49. Radi R (2004) Nitric oxide, oxidants, and protein tyrosine nitration. Proc Natl Acad Sci USA 101:4003-4008
50. Rubbo H, Radi R, Trujillo M et al. (1994) Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J Biol Chem 269: 26066-26075
51. Shibutani S, Takeshita M, Grollman AP (1991) Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 349:431-434
52. Shih SC, Smith LE (2005) Quantitative multi-gene transcriptional profiling using real-time PCR with a master template. Exp Mol Pathol 79:14-22
53. Shih SC, Zukauskas A, Li D et al. (2009) The L6 protein TM4SF1 is critical for endothelial cell function and tumor angiogenesis. Cancer Res 69:3272-3277
54. Strom SS, Yamamura Y (1997) Epidemiology of nonmelanoma skin cancer. Clin Plast Surg 24:627-636
55. Suri C, Jones PF, Patan S et al. (1996) Requisite role of angiopoietin-1, a ligand for the tie2 receptor, during embryonic angiogenesis. Cell 87:1171-1180
56. Suri C, McClain J, Thurston G et al. (1998) Increased vascularization in mice overexpressing angiopoietin-1. Science 282:468-471
57. Svobodova A, Walterova D, Vostalova J (2006) Ultraviolet light induced alteration to the skin. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 150:25-38
58. The International Agency for Research on Cancer Working Group on artificial ultraviolet light and skin, c (2007) The association of use of sunbeds with cutaneous malignant melanoma and other skin cancers: a systematic review. Intern J Cancer 120:1116-1122
59. Thurston G, Rudge JS, Ioffe E et al. (2000) Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 6:460-463
60. Thurston G, Suri C, Smith K et al. (1999) Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 286:2511-2514
61. Trifunovic A, Larsson NG (2008) Mitochondrial dysfunction as a cause of ageing. J Intern Med 263:167-178
62. Tsatmali M, Ancans J, Thody AJ (2002) Melanocyte function and its control by melanocortin peptides. J Histochem Cytochem 50:125-134
63. Van Slyke P, Alami J, Martin D et al. (2009) Acceleration of diabetic wound healing by an angiopoietin peptide mimetic. Tissue Eng Part A 15:1269-1280
64. Voskas D, Jones N, Van Slyke P et al. (2005) A cyclosporine-sensitive psoriasis-like disease produced in tie2 transgenic mice. Am J Pathol 166:843-855
65. 2-induced apoptosis through akt signaling. Biochem Biophys Res Commun 359:685-690
66. Weber CC, Cai H, Ehrbar M et al. (2005) Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothe-lial and vessel organization. J Biol Chem 280:22445-22453
67. Wolfram JA, Diaconu D, Hatala DA et al. (2009) Keratinocyte but not endothelial cell-specific overexpression of tie2 leads to the development of psoriasis. Am J Pathol 174:1443-1458
68. Wondrak GT (2007) Let the sun shine in: mechanisms and potential for therapeutics in skin photodamage. Curr Opin Investig Drugs 8:390-400
69. Xu Y, Yu Q (2001) Angiopoietin-1, unlike angiopoietin-2, is incorporated into the extracellular matrix via its linker peptide region. J Biol Chem 276:34990-34998
70. Yoshida Y, Togi K, Matsumae H et al. (2007) CCN1 protects cardiac myocytes from oxidative stress via beta1 integrin-akt pathway. Biochem Biophys Res Commun 355:611-618
71. Zastrow L, Groth N, Klein F et al. (2009) UV, visible and infrared light. Which wavelengths produce oxidative stress in human skin? Hautarzt 60:310-317
72. Zhang Z, Turner DC, Drzewiecki GJ et al. (1994) Impairment of integrin-mediated cell-matrix adhesion in oxidant-stressed PC12 cells. Brain Res 662:189-197
73. Zhao T, Benard V, Bohl BP et al. (2003) The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils. J Clin Invest 112:1732-1740
74. Zunino A, Degan P, Vigo T et al. (2001) Hydrogen peroxide: effects on DNA, chromosomes, cell cycle and apoptosis induction in Fanconi's anemia cell lines. Mutagenesis 16:283-288