PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 302, Issue 3, 2012, Pages

  Mihai, Cosmin ^a,b   Bao, Shengying ^b   Lai, Ju Ping ^b   Ghadiali, Samir N ^a,b   Knoell, Daren L ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Acute lung injury; Akt; Cell mechanics; Epithelium; Erk; Lung repair; Phosphatase and tensin homolog deleted on chromosome 10; Wound remodeling

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ARTICLE; ATOMIC FORCE MICROSCOPY; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FLUORESCENCE; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WOUND HEALING;

ACTIN CYTOSKELETON; BIOMECHANICS; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; ELECTRIC IMPEDANCE; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LUNG; LUNG INJURY; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, ATOMIC FORCE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; VANADIUM COMPOUNDS; WOUND HEALING;

EID: 84856674143     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00037.2011     Document Type: Article

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