Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice

Journal of Autoimmunity

Volumn 38, Issue 1, 2012, Pages 59-69

  Tischner, Denise ^a   Gaggl, Irene ^a   Peschel, Ines ^a   Kaufmann, Manuel ^a   Tuzlak, Selma ^a   Drach, Mathias ^b   Thuille, Nikolaus ^a   Villunger, Andreas ^a   Jan Wiegers, G ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b MEDICAL UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Apoptosis; Autoimmunity; Bcl 2; Bim; Regulatory T cells

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; BMF PROTEIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; MEMBRANE PROTEIN; PROTEIN BAD; PROTEIN BCL 2; PROTEIN NOXA; PUMA PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOIMMUNITY; BIOACCUMULATION; CD4+ T LYMPHOCYTE; CELL DEATH; COLITIS; CONTROLLED STUDY; FLOW CYTOMETRY; HISTOPATHOLOGY; INFLAMMATORY CELL; LAMINA PROPRIA; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; SPLEEN CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; CELLS, CULTURED; ETOPOSIDE; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; GREEN FLUORESCENT PROTEINS; INFLAMMATORY BOWEL DISEASES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

EID: 84856670788     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2011.12.008     Document Type: Article

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