Bezielle selectively targets mitochondria of cancer cells to inhibit glycolysis and OXPHOS

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Chen, Vivian ^a   Staub, Richard E ^a   Fong, Sylvia ^a   Tagliaferri, Mary ^a   Cohen, Isaac ^a   Shtivelman, Emma ^a  

^a Bionovo Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; BEZIELLE; BZL 101; GLUTATHIONE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SCUTELLARIA BARBATA EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ENERGY YIELD; ENZYME ACTIVATION; ENZYME INHIBITION; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; OXIDATION REDUCTION POTENTIAL; OXIDATIVE PHOSPHORYLATION; SCUTELLARIA; SCUTELLARIA BARBATA; BREAST TUMOR; DRUG EFFECT; FEMALE; MEDICINAL PLANT; METABOLISM; NEOPLASM; PATHOLOGY; TUMOR CELL LINE;

SCUTELLARIA BARBATA;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GLYCOLYSIS; HUMANS; MITOCHONDRIA; NEOPLASMS; OXIDATIVE PHOSPHORYLATION; PLANT EXTRACTS; PLANTS, MEDICINAL; REACTIVE OXYGEN SPECIES; SCUTELLARIA;

EID: 84856521923     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030300     Document Type: Article

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