Phase I trial and antitumor effects of BZL101 for patients with advanced breast cancer

Breast Cancer Research and Treatment

Volumn 105, Issue 1, 2007, Pages 17-28

  Rugo, Hope ^a   Shtivelman, Emma ^b   Perez, Alejandra ^c   Vogel, Charles ^d   Franco, Sandra ^c   Tan Chiu, Elizabeth ^d   Melisko, Michelle ^a   Tagliaferri, Mary ^b   Cohen, Isaac ^b   Shoemaker, Mark ^b   Tran, Zung ^e   Tripathy, Debu ^f,g  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Bionovo Inc   (United States)

^c MEMORIAL REGIONAL HOSPITAL   (United States)

^d Cancer Research Network   (United States)

^e UNIVERSITY OF COLORADO   (United States)

^f UNIVERSITY OF TEXAS AT DALLAS   (United States)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Advanced breast cancer; Botanical medicine; BZL101; Complementary and alternative medicine; Phase I clinical trial; Scutellaria barbata

Indexed keywords

ANTINEOPLASTIC AGENT; BZL 101; PLANT EXTRACT; SCUTELLARIA BARBATA EXTRACT; UNCLASSIFIED DRUG;

ADULT; ADVANCED CANCER; AGED; ANOREXIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLOATING; BREAST CANCER; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CHEMOTHERAPY INDUCED EMESIS; CHILL; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG EFFECT; DRUG INDUCED HEADACHE; DRUG RESPONSE; DRUG SAFETY; DRUG WITHDRAWAL; EPIGASTRIC BURNING; FATIGUE; FECES COLOR; FLATULENCE; GASTROINTESTINAL SYMPTOM; HOT FLUSH; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS; MUSCLE CRAMP; NAUSEA; PARESTHESIA; PATIENT COMPLIANCE; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SCUTELLARIA; SCUTELLARIA BARBATA; SIDE EFFECT; SINGLE DRUG DOSE; SKIN TINGLING; TREATMENT RESPONSE;

ADMINISTRATION, ORAL; ADULT; AGED; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASES; CELL LINE, TUMOR; DNA FRAGMENTATION; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; HUMANS; MIDDLE AGED; PLANT EXTRACTS; SCUTELLARIA;

EID: 34548046471     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-006-9430-6     Document Type: Article

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