BZL101, a phytochemical extract from the Scutellaria barbata plant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotype

Cancer Biology and Therapy

Volumn 10, Issue 4, 2010, Pages 397-405

  Marconett, Crystal N ^a   Morgenstern, Travis J ^a   San Roman, Adrianna K ^a   Sundar, Shyam N ^a   Singhal, Ankur K ^a   Firestone, Gary L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Breast cancer; BZL101; CDK gene expression; Cell cycle; Prostate cancer; Scutellaria barbata; Steroid receptors

Indexed keywords

ANDROGEN RECEPTOR; ANTINEOPLASTIC AGENT; BZL 101; CYCLIN DEPENDENT KINASE; ESTROGEN RECEPTOR ALPHA; PLANT MEDICINAL PRODUCT; SELECTIVE ESTROGEN RECEPTOR MODULATOR; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PHENOTYPE; PROSTATE CANCER; SCUTELLARIA; SCUTELLARIA BARBATA;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN A2; CYCLIN B1; CYCLIN D1; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; FEMALE; FLOW CYTOMETRY; G1 PHASE; GENE EXPRESSION; HUMANS; MALE; PHYTOTHERAPY; PLANT EXTRACTS; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; RECEPTORS, GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCUTELLARIA;

EID: 77957173100     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.10.4.12424     Document Type: Article

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