Impaired mitochondrial Ca2+ homeostasis in respiratory chain-deficient cells but efficient compensation of energetic disadvantage by enhanced anaerobic glycolysis due to low ATP steady state levels

Experimental Cell Research

Volumn 313, Issue 14, 2007, Pages 3076-3089

  von Kleist Retzow, Jürgen Christoph ^a   Hornig Do, Hue Tran ^a   Schauen, Matthias ^a   Eckertz, Sabrina ^a   Dinh, Tuan Anh Duong ^a   Stassen, Frank ^a   Lottmann, Nadine ^a   Bust, Maria ^a   Galunska, Bistra ^b   Wielckens, Klaus ^a   Hein, Wolfgang ^a   Beuth, Joseph ^a   Braun, Jan Matthias ^a   Fischer, Jürgen H ^a   Ganitkevich, Vladimir Y ^a,c   Maniura Weber, Katharina ^a   Wiesner, Rudolf J ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b MEDICAL UNIVERSITY OF VARNA   (Bulgaria)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

143B cells; Adenine nucleotides; Anaerobic glycolysis; Cell culture; MELAS; Mitochondria; Mitochondrial disease; ROS production; tRNALeu(UUR)

Indexed keywords

ADENINE; ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM ION; GUANINE; LEUCINE; MITOCHONDRIAL DNA; SUPEROXIDE; TRANSFER RNA; AMINO ACID; ANTIOXIDANT; CALCIUM; LACTIC ACID; REACTIVE OXYGEN METABOLITE;

ANAEROBIC GLYCOLYSIS; ARTICLE; CALCIUM HOMEOSTASIS; CANCER CELL CULTURE; CELL CULTURE; CELL ENERGY; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; CYBRID; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENERGY YIELD; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; NUCLEOTIDE SEQUENCE; OSTEOSARCOMA CELL; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; POINT MUTATION; PRIORITY JOURNAL; RESPIRATORY CHAIN; STEADY STATE; CELL MEMBRANE POTENTIAL; ELECTRON TRANSPORT; GLYCOLYSIS; HOMEOSTASIS; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PH; PHENOTYPE; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ANTIOXIDANTS; CALCIUM; CELL LINE; ELECTRON TRANSPORT; GLYCOLYSIS; HOMEOSTASIS; HUMANS; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MEMBRANE POTENTIALS; MITOCHONDRIA; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENOTYPE; REACTIVE OXYGEN SPECIES;

EID: 34547146580     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.04.015     Document Type: Article

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