Genetic targeting of the active transcription factor XBP1s to dendritic cells potentiates vaccine-induced prophylactic and therapeutic antitumor immunity

Molecular Therapy

Volumn 20, Issue 2, 2012, Pages 432-442

  Tian, Shenghe ^a   Liu, Zuqiang ^a   Donahue, Cara ^a   Falo, Louis D ^a,b   You, Zhaoyang ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD70 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; CD8ALPHA ANTIGEN; CHEMOKINE RECEPTOR CCR7; CYTOMEGALOVIRUS VACCINE; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; INTERLEUKIN 6; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR XBP1S; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; DNA MODIFICATION; DRUG EFFICACY; FEMALE; GENE TARGETING; GENETIC TRANSCRIPTION; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TH1 CELL; UPREGULATION;

CYTOMEGALOVIRUS;

EID: 84856521693     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.183     Document Type: Article

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