-
1
-
-
0016621840
-
Cannabis: Effects on hunger and thirst
-
Abel EL1975) Cannabis: effects on hunger and thirst. Behav Biol 15:255-281
-
(1975)
Behav. Biol.
, vol.15
, pp. 255-281
-
-
Abel, E.L.1
-
2
-
-
31144466379
-
Molecular biology of cannabinoid receptors
-
Abood ME2005) Molecular biology of cannabinoid receptors. Handb Exp Pharmacol 168:81-115
-
(2005)
Handb. Exp. Pharmacol.
, vol.168
, pp. 81-115
-
-
Abood, M.E.1
-
3
-
-
37449007904
-
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake
-
Addy C, Wright H, van Laere K, Gantz I, Erondu N, Musser BJ, Lu K, Yuan J, Sanabria- Bohorquez SM, Stoch A, Stevens C, Fong TM, De Lepeleire I, Cilissen C, Cote J, Rosko K, Gendrano IN III, Nguyen AM, Gumbiner B, Rothenberg P, de Hoon J, Bormans G, Depre M, Eng WS, Ravussin E, Klein S, Blundell J, Herman GA, Burns HD, Hargreaves RJ, Wagner J, Gottesdiener K, Amatruda JM, Heymsfield SB2008) The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake. Cell Metab 7:68-78
-
(2008)
Cell Metab.
, vol.7
, pp. 68-78
-
-
Addy, C.1
Wright, H.2
Van Laere, K.3
Gantz, I.4
Erondu, N.5
Musser, B.J.6
Lu, K.7
Yuan, J.8
Sanabria-Bohorquez, S.M.9
Stoch, A.10
Stevens, C.11
Fong, T.M.12
De Lepeleire, I.13
Cilissen, C.14
Cote, J.15
Rosko, K.16
Gendrano III, I.N.17
Nguyen, A.M.18
Gumbiner, B.19
Rothenberg, P.20
De Hoon, J.21
Bormans, G.22
Depre, M.23
Eng, W.S.24
Ravussin, E.25
Klein, S.26
Blundell, J.27
Herman, G.A.28
Burns, H.D.29
Hargreaves, R.J.30
Wagner, J.31
Gottesdiener, K.32
Amatruda, J.M.33
Heymsfield, S.B.34
more..
-
4
-
-
77951225636
-
Endocannabinoid control of gastric sensorimotor function in man
-
Ameloot K, Janssen P, Scarpellini E, Vos R, Boesmans W, Depoortere I, Vanden BP, Tack J2010) Endocannabinoid control of gastric sensorimotor function in man. Aliment Pharmacol Ther 31:1123-1131
-
(2010)
Aliment Pharmacol. Ther.
, vol.31
, pp. 1123-1131
-
-
Ameloot, K.1
Janssen, P.2
Scarpellini, E.3
Vos, R.4
Boesmans, W.5
Depoortere, I.6
Vanden, B.P.7
Tack, J.8
-
5
-
-
0030738512
-
Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors
-
DOI 10.1007/s002130050326
-
Arnone M, Maruani J, Chaperon F, Thiebot MH, Poncelet M, Soubrie P, Le Fur G1997) Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoidCB1) receptors. PsychopharmacologyBerl) 132:104-106 (Pubitemid 27303746)
-
(1997)
Psychopharmacology
, vol.132
, Issue.1
, pp. 104-106
-
-
Arnone, M.1
Maruani, J.2
Chaperon, F.3
Thiebot, M.-H.4
Poncelet, M.5
Soubrie, P.6
Le Fur, G.7
-
6
-
-
77952290161
-
A clinical trial assessing the safety and efficacy of taranabant a CB1R inverse agonist in obese and overweight patients: A high-dose study
-
Lond
-
Aronne LJ, Tonstad S, Moreno M, Gantz I, Erondu N, Suryawanshi S, Molony C, Sieberts S, Nayee J, Meehan AG, Shapiro D, Heymsfield SB, Kaufman KD, Amatruda JM2010) A clinical trial assessing the safety and efficacy of taranabant, a CB1R inverse agonist, in obese and overweight patients: a high-dose study. Int J ObesLond) 34:919-935
-
(2010)
Int. J. Obes.
, vol.34
, pp. 919-935
-
-
Aronne, L.J.1
Tonstad, S.2
Moreno, M.3
Gantz, I.4
Erondu, N.5
Suryawanshi, S.6
Molony, C.7
Sieberts, S.8
Nayee, J.9
Meehan, A.G.10
Shapiro, D.11
Heymsfield, S.B.12
Kaufman, K.D.13
Amatruda, J.M.14
-
7
-
-
8544278893
-
Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome-associated anorexia
-
DOI 10.1016/S0885-3924(97)00038-9, PII S0885392497000389
-
Beal JE, Olson R, Lefkowitz L, Laubenstein L, Bellman P, Yangco B, Morales JO, Murphy R, Powderly W, Plasse TF, Mosdell KW, Shepard KV1997) Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome-associated anorexia. J Pain Symptom Manage 14:7-14 (Pubitemid 27287406)
-
(1997)
Journal of Pain and Symptom Management
, vol.14
, Issue.1
, pp. 7-14
-
-
Beal, J.E.1
Olson, R.2
Lefkowitz, L.3
Laubenstein, L.4
Bellman, P.5
Yangco, B.6
Morales, J.O.7
Murphy, R.8
Powderly, W.9
Plasse, T.F.10
Mosdell, K.W.11
Shepard, K.V.12
-
8
-
-
78651301281
-
Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: A controlled laboratory study
-
Bedi G, Foltin RW, Gunderson EW, Rabkin J, Hart CL, Comer SD, Vosburg SK, Haney M2010) Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study. PsychopharmacologyBerl) 212:675-686
-
(2010)
PsychopharmacologyBerl
, vol.212
, pp. 675-686
-
-
Bedi, G.1
Foltin, R.W.2
Gunderson, E.W.3
Rabkin, J.4
Hart, C.L.5
Comer, S.D.6
Vosburg, S.K.7
Haney, M.8
-
9
-
-
0037374766
-
1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells
-
DOI 10.1124/mol.63.4.908
-
Bensaid M, Gary-Bobo M, Esclangon A, Maffrand JP, Le Fur G, Oury-Donat F, Soubrie P2003) The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Mol Pharmacol 63:908-914 (Pubitemid 36368998)
-
(2003)
Molecular Pharmacology
, vol.63
, Issue.4
, pp. 908-914
-
-
Bensaid, M.1
Gary-Bobo, M.2
Esclangon, A.3
Maffrand, J.P.4
Le Fur, G.5
Oury-donat, F.6
Soubrie, P.7
-
10
-
-
33845522074
-
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity
-
DOI 10.2337/db06-0812
-
Bluher M, Engeli S, Kloting N, Berndt J, Fasshauer M, Batkai S, Pacher P, Schon MR, Jordan J, StumvollM(2006) Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity. Diabetes 55:3053-3060 (Pubitemid 44923642)
-
(2006)
Diabetes
, vol.55
, Issue.11
, pp. 3053-3060
-
-
Bluher, M.1
Engeli, S.2
Kloting, N.3
Berndt, J.4
Fasshauer, M.5
Batkai, S.6
Pacher, P.7
Schon, M.R.8
Jordan, J.9
Stumvoll, M.10
-
11
-
-
1642298863
-
Expression of Cannabinoid CB1 Receptors by Vagal Afferent Neurons, Is Inhibited by Cholecystokinin
-
DOI 10.1523/JNEUROSCI.5404-03.2004
-
Burdyga G, Lal S, Varro A, Dimaline R, Thompson DG, Dockray GJ2004) Expression of cannabinoid CB1 receptors by vagal afferent neurons is inhibited by cholecystokinin. J Neurosci 24:2708-2715 (Pubitemid 38380947)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.11
, pp. 2708-2715
-
-
Burdyga, G.1
Lal, S.2
Varro, A.3
Dimaline, R.4
Thompson, D.G.5
Dockray, G.J.6
-
12
-
-
33646856625
-
Ghrelin receptors in rat and human nodose ganglia: Putative role in regulating CB-1 and MCH receptor abundance
-
DOI 10.1152/ajpgi.00543.2005
-
Burdyga G, Varro A, Dimaline R, Thompson DG, Dockray GJ2006) Ghrelin receptors in rat and human nodose ganglia: putative role in regulating CB-1 and MCH receptor abundance. Am J Physiol Gastrointest Liver Physiol 290:G1289-G1297 (Pubitemid 43788312)
-
(2006)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.290
, Issue.6
-
-
Burdyga, G.1
Varro, A.2
Dimaline, R.3
Thompson, D.G.4
Dockray, G.J.5
-
13
-
-
77954371737
-
Expression of cannabinoid CB1 receptors by vagal afferent neurons: Kinetics and role in influencing neurochemical phenotype
-
Burdyga G, Varro A, Dimaline R, Thompson DG, Dockray GJ2010) Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. Am J Physiol Gastrointest Liver Physiol 299:G63-G69
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.299
-
-
Burdyga, G.1
Varro, A.2
Dimaline, R.3
Thompson, D.G.4
Dockray, G.J.5
-
14
-
-
34547411013
-
18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor
-
DOI 10.1073/pnas.0703472104
-
Burns HD, van Laere K, Sanabria-Bohorquez S, Hamill TG, Bormans G, Eng WS, Gibson R, Ryan C, Connolly B, Patel S, Krause S, Vanko A, van Hecken A, Dupont P, De Lepeleire I, Rothenberg P, Stoch SA, Cote J, Hagmann WK, Jewell JP, Lin LS, Liu P, Goulet MT, Gottesdiener K, Wagner JA, de Hoon J, Mortelmans L, Fong TM, Hargreaves RJ2007) [18F]MK-9470, a positron emission tomographyPET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor. Proc Natl Acad Sci U S A 104:9800-9805 (Pubitemid 47175347)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.23
, pp. 9800-9805
-
-
Burns, H.D.1
Van Laere, K.2
Sanabria-Bohorquez, S.3
Hamill, T.G.4
Bormans, G.5
Eng, W.-S.6
Gibson, R.7
Ryan, C.8
Connolly, B.9
Patel, S.10
Krause, S.11
Vanko, A.12
Van Hecken, A.13
Dupont, P.14
De Lepeleire, I.15
Rothenberg, P.16
Stoch, S.A.17
Cote, J.18
Hagmann, W.K.19
Jewell, J.P.20
Lin, L.S.21
Liu, P.22
Goulet, M.T.23
Gottesdiener, K.24
Wagner, J.A.25
De Hoon, J.26
Mortelmans, L.27
Fong, T.M.28
Hargreaves, R.J.29
more..
-
15
-
-
9444265979
-
Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide
-
DOI 10.1079/BJN20041256
-
Cani PD, Montoya ML, Neyrinck AM, Delzenne NM, Lambert DM2004) Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716Arimonabant) and oleoylethanolamide. Br J Nutr 92:757-761 (Pubitemid 39562153)
-
(2004)
British Journal of Nutrition
, vol.92
, Issue.5
, pp. 757-761
-
-
Cani, P.D.1
Montoya, M.L.2
Neyrinck, A.M.3
Delzenne, N.M.4
Lambert, D.M.5
-
16
-
-
33748078481
-
1 receptor antagonists in reducing food intake and body weight: Preclinical and clinical data
-
DOI 10.1111/j.1527-3458.2006.00091.x
-
Carai MA, Colombo G, Maccioni P, Gessa GL2006) Efficacy of rimonabant and other cannabinoid CB1 receptor antagonists in reducing food intake and body weight: preclinical and clinical data. CNS Drug Rev 12:91-99 (Pubitemid 44300378)
-
(2006)
CNS Drug Reviews
, vol.12
, Issue.2
, pp. 91-99
-
-
Carai, M.A.M.1
Colombo, G.2
Maccioni, P.3
Gessa, G.L.4
-
17
-
-
33847306530
-
Effects of cannabinoid receptors on skeletal muscle oxidative pathways
-
Cavuoto P, McAinch AJ, Hatzinikolas G, Cameron-Smith D, Wittert GA2007) Effects of cannabinoid receptors on skeletal muscle oxidative pathways. Mol Cell Endocrinol 267:63-69
-
(2007)
Mol. Cell Endocrinol.
, vol.267
, pp. 63-69
-
-
Cavuoto, P.1
McAinch, A.J.2
Hatzinikolas, G.3
Cameron-Smith, D.4
Wittert, G.A.5
-
18
-
-
0032541111
-
Appetite suppression and weight loss after the cannabinoid antagonist SR 141716
-
Colombo G, Agabio R, Diaz G, Lobina C, Reali R, Gessa GL1998) Appetite suppression and weight loss after the cannabinoid antagonist SR 141716. Life Sci 63:L113-L117
-
(1998)
Life Sci.
, vol.63
-
-
Colombo, G.1
Agabio, R.2
Diaz, G.3
Lobina, C.4
Reali, R.5
Gessa, G.L.6
-
19
-
-
85047690626
-
The endogenous cennabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
-
DOI 10.1172/JCI200317725
-
Cota D, Marsicano G, Tschop M, Grubler Y, Flachskamm C, Schubert M, Auer D, Yassouridis A, Thone-Reineke C, Ortmann S, Tomassoni F, Cervino C, Nisoli E, Linthorst AC, Pasquali R, Lutz B, Stalla GK, Pagotto U2003) The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 112:423-431 (Pubitemid 38063771)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.3
, pp. 423-431
-
-
Cota, D.1
Marsicano, G.2
Tschop, M.3
Grubler, Y.4
Flachskamm, C.5
Schubert, M.6
Auer, D.7
Yassouridis, A.8
Thone-Reineke, C.9
Ortmann, S.10
Tomassoni, F.11
Cervino, C.12
Nisoli, E.13
Linthorst, A.C.E.14
Pasquali, R.15
Lutz, B.16
Stalla, G.K.17
Pagotto, U.18
-
20
-
-
33947606528
-
Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men
-
DOI 10.1038/sj.ijo.0803539, PII 0803539
-
Coté M, Matias I, Lemieux I, Petrosino S, Almeras N, Després JP, Di Marzo V2007) Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. Int J ObesLond) 31:692-699 (Pubitemid 46482358)
-
(2007)
International Journal of Obesity
, vol.31
, Issue.4
, pp. 692-699
-
-
Cote, M.1
Matias, I.2
Lemieux, I.3
Petrosino, S.4
Almeras, N.5
Despres, J.-P.6
Di Marzo, V.7
-
21
-
-
27844463517
-
Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
-
DOI 10.1056/NEJMoa044537
-
Després JP, Golay A, Sjostrom L2005) Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 353:2121-2134 (Pubitemid 41653104)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.20
, pp. 2121-2134
-
-
Despres, J.-P.1
Golay, A.2
Sjostrom, L.3
-
22
-
-
0024263922
-
Determination and characterization of a cannabinoid receptor in rat brain
-
Devane WA, Dysarz FA III, Johnson MR, Melvin LS, Howlett AC1988) Determination and characterization of a cannabinoid receptor in rat brain. Mol Pharmacol 34:605-613 (Pubitemid 19007296)
-
(1988)
Molecular Pharmacology
, vol.34
, Issue.5
, pp. 605-613
-
-
Devane, W.A.1
Dysarz III, F.A.2
Johnson, M.R.3
Melvin, L.S.4
Howlett, A.C.5
-
23
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Etinger A, Mechoulam R1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258:1946-1949 (Pubitemid 23026736)
-
(1992)
Science
, vol.258
, Issue.5090
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
24
-
-
0035848818
-
Leptin-regulated endocannabinoids are involved in maintaining food intake
-
DOI 10.1038/35071088
-
Di Marzo V, Goparaju SK, Wang L, Liu J, Batkai S, Jarai Z, Fezza F, Miura GI, Palmiter RD, Sugiura T, Kunos G2001) Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 410:822-825 (Pubitemid 32303781)
-
(2001)
Nature
, vol.410
, Issue.6830
, pp. 822-825
-
-
Di Marzo, V.1
Goparaju, S.K.2
Wang, L.3
Liu, J.4
Batkai, S.5
Jarai, Z.6
Fezza, F.7
Miura, G.I.8
Palmiter, R.D.9
Sugiura, T.10
Kunos, G.11
-
25
-
-
33645794041
-
The biosyn thesis fate and pharmacological properties of endocannabinoids
-
Di Marzo V, De Petrocellis L, Bisogno T2005) The biosynthesis, fate and pharmacological properties of endocannabinoids. Handb Exp Pharmacol 168:147-185
-
(2005)
Handb. Exp. Pharmacol.
, vol.168
, pp. 147-185
-
-
Di Marzo, V.1
De Petrocellis, L.2
Bisogno, T.3
-
26
-
-
40949147440
-
The role of endocannabinoids in the regulation of gastric emptying: Alterations in mice fed a high-fat diet
-
DOI 10.1038/sj.bjp.0707682, PII 0707682
-
Di Marzo V, Capasso R, Matias I, Aviello G, Petrosino S, Borrelli F, Romano B, Orlando P, Capasso F, Izzo AA2008) The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. Br J Pharmacol 153:1272-1280 (Pubitemid 351415503)
-
(2008)
British Journal of Pharmacology
, vol.153
, Issue.6
, pp. 1272-1280
-
-
Di Marzo, V.1
Capasso, R.2
Matias, I.3
Aviello, G.4
Petrosino, S.5
Borrelli, F.6
Romano, B.7
Orlando, P.8
Capasso, F.9
Izzo, A.A.10
-
27
-
-
70449726605
-
Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects
-
Di Marzo V, Verrijken A, Hakkarainen A, Petrosino S, Mertens I, Lundbom N, Piscitelli F, Westerbacka J, Soro-Paavonen A, Matias I, Van GL, Taskinen MR2009a) Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. Eur J Endocrinol 161:715-722
-
(2009)
Eur. J. Endocrinol.
, vol.161
, pp. 715-722
-
-
Di Marzo, V.1
Verrijken, A.2
Hakkarainen, A.3
Petrosino, S.4
Mertens, I.5
Lundbom, N.6
Piscitelli, F.7
Westerbacka, J.8
Soro-Paavonen, A.9
Matias, I.10
Van, G.L.11
Taskinen, M.R.12
-
28
-
-
58149471799
-
Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors
-
Di Marzo V, Coté M, Matias I, Lemieux I, Arsenault BJ, Cartier A, Piscitelli F, Petrosino S, Almeras N, Després JP2009b) Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. Diabetologia 52:213-217
-
(2009)
Diabetologia
, vol.52
, pp. 213-217
-
-
Di Marzo, V.1
Coté, M.2
Matias, I.3
Lemieux, I.4
Arsenault, B.J.5
Cartier, A.6
Piscitelli, F.7
Petrosino, S.8
Almeras, N.9
Després, J.P.10
-
29
-
-
57349122335
-
Inhibiting parabrachial fatty acid amide hydrolase activity selectively increases the intake of palatable food via cannabinoid CB1 receptors
-
Dipatrizio NV, Simansky KJ2008) Inhibiting parabrachial fatty acid amide hydrolase activity selectively increases the intake of palatable food via cannabinoid CB1 receptors. Am J Physiol Regul Integr Comp Physiol 295:R1409-R1414
-
(2008)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.295
-
-
Dipatrizio, N.V.1
Simansky, K.J.2
-
30
-
-
42449135761
-
Dysregulation of the endocannabinoid system in obesity
-
DOI 10.1111/j.1365-2826.2008.01683.x
-
Engeli S2008a) Dysregulation of the endocannabinoid system in obesity. J Neuroendocrinol 20Suppl 1):110-115 (Pubitemid 351559284)
-
(2008)
Journal of Neuroendocrinology
, vol.20
, Issue.SUPPL. 1
, pp. 110-115
-
-
Engeli, S.1
-
31
-
-
77951595914
-
Peripheral metabolic effects of endocannabinoids and cannabinoid receptor blockade
-
Engeli S2008b) Peripheral metabolic effects of endocannabinoids and cannabinoid receptor blockade. Obes Facts 1:8-15
-
(2008)
Obes. Facts.
, vol.1
, pp. 8-15
-
-
Engeli, S.1
-
32
-
-
25844460609
-
Activation of the peripheral endocannabinoid system in human obesity
-
DOI 10.2337/diabetes.54.10.2838
-
Engeli S, Bohnke J, Feldpausch M, Gorzelniak K, Janke J, Batkai S, Pacher P, Harvey-White J, Luft FC, Sharma AM, Jordan J2005) Activation of the peripheral endocannabinoid system in human obesity. Diabetes 54:2838-2843 (Pubitemid 41401077)
-
(2005)
Diabetes
, vol.54
, Issue.10
, pp. 2838-2843
-
-
Engeli, S.1
Bohnke, J.2
Feldpausch, M.3
Gorzelniak, K.4
Janke, J.5
Batkai, S.6
Pacher, P.7
Harvey-White, J.8
Luft, F.C.9
Sharma, A.M.10
Jordan, J.11
-
33
-
-
0023794545
-
Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory
-
Foltin RW, Fischman MW, Byrne MF1988) Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory. Appetite 11:1-14
-
(1988)
Appetite
, vol.11
, pp. 1-14
-
-
Foltin, R.W.1
Fischman, M.W.2
Byrne, M.F.3
-
34
-
-
70349128141
-
Cannabinoid-1 receptor inverse agonists: Current understanding of mechanism of action and unanswered questions
-
Lond)
-
Fong TM, Heymsfield SB2009) Cannabinoid-1 receptor inverse agonists: current understanding of mechanism of action and unanswered questions. Int J ObesLond) 33:947-955
-
(2009)
Int. J. Obes.
, vol.33
, pp. 947-955
-
-
Fong, T.M.1
Heymsfield, S.B.2
-
35
-
-
34248532300
-
Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl] -2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), in rodents
-
DOI 10.1124/jpet.106.118737
-
Fong TM, Guan XM, Marsh DJ, Shen CP, Stribling DS, Rosko KM, Lao J, Yu H, Feng Y, Xiao JC, Van der Ploeg LH, Goulet MT, Hagmann WK, Lin LS, Lanza TJ Jr, Jewell JP, Liu P, Shah SK, Qi H, Tong X, Wang J, Xu SS, Francis B, Strack AM, MacIntyre DE, Shearman LP2007) Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4- chlorophenyl)-2-(3-cyanophenyl)-1- methylpropyl]-2-methyl-2-[[5-(t rifluoromethyl)pyridin- 2-yl]oxy]propanamideMK- 0364), in rodents. J Pharmacol Exp Ther 321:1013-1022 (Pubitemid 46762708)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.3
, pp. 1013-1022
-
-
Fong, T.M.1
Guan, X.-M.2
Marsh, D.J.3
Shen, C.-P.4
Stribling, D.S.5
Rosko, K.M.6
Lao, J.7
Yu, H.8
Feng, Y.9
Xiao, J.C.10
Van Der Ploeg, L.H.T.11
Goulet, M.T.12
Hagmann, W.K.13
Lin, L.S.14
Lanza Jr., T.J.15
Jewell, J.P.16
Liu, P.17
Shah, S.K.18
Qi, H.19
Tong, X.20
Wang, J.21
Xu, S.S.22
Francis, B.23
Strack, A.M.24
MacIntyre, D.E.25
Shearman, L.P.26
more..
-
36
-
-
0016699877
-
Effects of marijuana and D-amphetamine on the appetite food consumption and various cardio-respiratory variables in man union
-
Gagnon MA, Elie R1975) Effects of marijuana and D-amphetamine on the appetite, food consumption and various cardio-respiratory variables in man. Union Med Can 104:914-921
-
(1975)
Med. Can.
, vol.104
, pp. 914-921
-
-
Gagnon, M.A.1
Elie, R.2
-
37
-
-
33947489961
-
Isolation structure and partial synthesis of an active constituent of hashish
-
Gaoni Y, Mechoulam R1964) Isolation, structure and partial synthesis of an active constituent of hashish. J Am Chem Soc 86:1646
-
(1964)
J. Am. Chem. Soc.
, vol.86
, pp. 1646
-
-
Gaoni, Y.1
Mechoulam, R.2
-
38
-
-
34547423962
-
Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese zucker fa/fa rats
-
DOI 10.1002/hep.21641
-
Gary-Bobo M, Elachouri G, Gallas JF, Janiak P, Marini P, Ravinet Trillou C, Chabbert M, Cruccioli N, Pfersdorff C, Roque C, Arnone M, Croci T, Soubrie P, Oury-Donat F, Maffrand JP, Scatton B, Lacheretz F, Le Fur G, Herbert JM, Bensaid M2007) Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats. Hepatology 46:122-129 (Pubitemid 47171928)
-
(2007)
Hepatology
, vol.46
, Issue.1
, pp. 122-129
-
-
Gary-Bobo, M.1
Elachouri, G.2
Gallas, J.F.3
Janiak, P.4
Marini, P.5
Ravinet-Trillou, C.6
Chabbert, M.7
Cruccioli, N.8
Pfersdorff, C.9
Roque, C.10
Arnone, M.11
Croci, T.12
Soubrie, P.13
Oury-Donat, F.14
Maffrand, J.P.15
Scatton, B.16
Lacheretz, F.17
Le Fur, G.18
Herbert, J.M.19
Bensaid, M.20
more..
-
39
-
-
0036849961
-
A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding
-
Gomez R, Navarro M, Ferrer B, Trigo JM, Bilbao A, Del Arco I, Cippitelli A, Nava F, Piomelli D, Rodriguez dF2002) A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding. J Neurosci 22:9612-9617 (Pubitemid 35356203)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.21
, pp. 9612-9617
-
-
Gomez, R.1
Navarro, M.2
Ferrer, B.3
Trigo, J.M.4
Bilbao, A.5
Arco, I.D.6
Cippitelli, A.7
Nava, F.8
Piomelli, D.9
De Fonseca, F.R.10
-
40
-
-
0026507485
-
Dronabinol effects on weight in patients with HIV infection
-
Gorter R, Seefried M, Volberding P1992) Dronabinol effects on weight in patients with HIV infection. AIDS 6:127
-
(1992)
AIDS
, vol.6
, pp. 127
-
-
Gorter, R.1
Seefried, M.2
Volberding, P.3
-
42
-
-
0037131098
-
Down-regulation of cannabinoid- 1CB-1 receptors in specific extrahypothalamic regions of rats with dietary obesity: A role for endogenous cannabinoids in driving appetite for palatable food
-
Harrold JA, Elliott JC, King PJ, Widdowson PS, Williams G2002) Down-regulation of cannabinoid- 1CB-1) receptors in specific extrahypothalamic regions of rats with dietary obesity: a role for endogenous cannabinoids in driving appetite for palatable food? Brain Res 952:232-238
-
(2002)
Brain Res.
, vol.952
, pp. 232-238
-
-
Harrold, J.A.1
Elliott, J.C.2
King, P.J.3
Widdowson, P.S.4
Williams, G.5
-
43
-
-
0014975470
-
Hunger and appetite after single doses of marihuana alcohol and dextroamphetamine
-
Hollister LE1971) Hunger and appetite after single doses of marihuana, alcohol, and dextroamphetamine. Clin Pharmacol Ther 12:44-49
-
(1971)
Clin. Pharmacol. Ther.
, vol.12
, pp. 44-49
-
-
Hollister, L.E.1
-
44
-
-
33645796477
-
Cannabinoid receptor signaling
-
Howlett AC2005) Cannabinoid receptor signaling. Handb Exp Pharmacol 168:53-79
-
(2005)
Handb. Exp. Pharmacol.
, vol.168
, pp. 53-79
-
-
Howlett, A.C.1
-
45
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
DOI 10.1124/pr.54.2.161
-
Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG2002) International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 54:161-202 (Pubitemid 34575709)
-
(2002)
Pharmacological Reviews
, vol.54
, Issue.2
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
Mechoulam, R.11
Pertwee, R.G.12
-
46
-
-
68349129115
-
Peripheral endocannabinoid dysregulation in obesity: Relation to intestinal motility and energy processing induced by food deprivation and re-feeding
-
Izzo AA, Piscitelli F, Capasso R, Aviello G, Romano B, Borrelli F, Petrosino S, Di Marzo V2009) Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. Br J Pharmacol 158:451-461
-
(2009)
Br. J. Pharmacol.
, vol.158
, pp. 451-461
-
-
Izzo, A.A.1
Piscitelli, F.2
Capasso, R.3
Aviello, G.4
Romano, B.5
Borrelli, F.6
Petrosino, S.7
Di Marzo, V.8
-
47
-
-
0035185205
-
Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats
-
Jamshidi N, Taylor DA2001) Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. Br J Pharmacol 134:1151-1154 (Pubitemid 33097243)
-
(2001)
British Journal of Pharmacology
, vol.134
, Issue.6
, pp. 1151-1154
-
-
Jamshidi, N.1
Taylor, D.A.2
-
48
-
-
24644500204
-
The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance
-
DOI 10.1096/fj.04-3177fje
-
Jbilo O, Ravinet Trillou C, Arnone M, Buisson I, Bribes E, Peleraux A, Penarier G, Soubrie P, Le Fur G, Galiegue S, Casellas P2005) The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance. FASEB J 19:1567-1569 (Pubitemid 41279033)
-
(2005)
FASEB Journal
, vol.19
, Issue.11
, pp. 1567-1569
-
-
Jbilo, O.1
Ravinet-Trillou, C.2
Arnone, M.3
Buisson, I.4
Bribes, E.5
Peleraux, A.6
Penarier, G.7
Soubrie, P.8
Le Fur, G.9
Galiegue, S.10
Casellas, P.11
-
49
-
-
29144464338
-
Integration of endocannabinoid and leptin signaling in an appetite-related neural circuit
-
DOI 10.1016/j.neuron.2005.10.021, PII S089662730500886X
-
Jo YH, Chen YJ, Chua SC Jr, Talmage DA, Role LW2005) Integration of endocannabinoid and leptin signaling in an appetite-related neural circuit. Neuron 48:1055-1066 (Pubitemid 41814707)
-
(2005)
Neuron
, vol.48
, Issue.6
, pp. 1055-1066
-
-
Jo, Y.-H.1
Chen, Y.-J.J.2
Chua Jr., S.C.3
Talmage, D.A.4
Role, L.W.5
-
50
-
-
57049102251
-
End of the line for cannabinoid receptor 1 as an anti-obesity target
-
Jones D2008) End of the line for cannabinoid receptor 1 as an anti-obesity target? Nat Rev Drug Discov 7:961-962
-
(2008)
Nat. Rev. Drug. Discov.
, vol.7
, pp. 961-962
-
-
Jones, D.1
-
51
-
-
78651264786
-
European society of hypertension working group on obesity: Obesity drugs and cardiovascular outcomes
-
Jordan J, Schlaich M, Redon J, Narkiewicz K, Luft FC, Grassi G, Dixon J, Lambert G, Engeli S2011) European Society of Hypertension Working Group on Obesity: obesity drugs and cardiovascular outcomes. J Hypertens 29:189-193
-
(2011)
J. Hypertens.
, vol.29
, pp. 189-193
-
-
Jordan, J.1
Schlaich, M.2
Redon, J.3
Narkiewicz, K.4
Luft, F.C.5
Grassi, G.6
Dixon, J.7
Lambert, G.8
Engeli, S.9
-
52
-
-
77952290508
-
A one-year study to assess the safety and efficacy of the CB1R inverse agonist taranabant in overweight and obese patients with type 2 diabetes
-
Kipnes MS, Hollander P, Fujioka K, Gantz I, Seck T, Erondu N, Shentu Y, Lu K, Suryawanshi S, Chou M, Johnson-Levonas AO, Heymsfield SB, Shapiro D, Kaufman KD, Amatruda JM2010) A one-year study to assess the safety and efficacy of the CB1R inverse agonist taranabant in overweight and obese patients with type 2 diabetes. Diabetes Obes Metab 12:517-531
-
(2010)
Diabetes. Obes. Metab.
, vol.12
, pp. 517-531
-
-
Kipnes, M.S.1
Hollander, P.2
Fujioka, K.3
Gantz, I.4
Seck, T.5
Erondu, N.6
Shentu, Y.7
Lu, K.8
Suryawanshi, S.9
Chou, M.10
Johnson-Levonas, A.O.11
Heymsfield, S.B.12
Shapiro, D.13
Kaufman, K.D.14
Amatruda, J.M.15
-
54
-
-
0035984946
-
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol
-
Kirkham TC, Williams CM, Fezza F, Di Marzo V2002) Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. Br J Pharmacol 136:550-557 (Pubitemid 34717699)
-
(2002)
British Journal of Pharmacology
, vol.136
, Issue.4
, pp. 550-557
-
-
Kirkham, T.C.1
Williams, C.M.2
Fezza, F.3
Di Marzo, V.4
-
55
-
-
21644453934
-
Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase
-
DOI 10.1074/jbc.C500175200
-
Kola B, Hubina E, Tucci SA, Kirkham TC, Garcia EA, Mitchell SE, Williams LM, Hawley SA, Hardie DG, Grossman AB, Korbonits M2005) Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. J Biol Chem 280:25196-25201 (Pubitemid 40934612)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.26
, pp. 25196-25201
-
-
Kola, B.1
Hubina, E.2
Tucci, S.A.3
Kirkham, T.C.4
Garcia, E.A.5
Mitchell, S.E.6
Williams, L.M.7
Hawley, S.A.8
Hardie, D.G.9
Grossman, A.B.10
Korbonits, M.11
-
56
-
-
43449091899
-
Effects of rimonabant, a cannabinoid CB1 receptor ligand, on energy expenditure in lean rats
-
DOI 10.1038/ijo.2008.3, PII IJO20083
-
Kunz I, Meier MK, Bourson A, Fisseha M, Schilling W2008) Effects of rimonabant, a cannabinoid CB1 receptor ligand, on energy expenditure in lean rats. Int J ObesLond) 32:863-870 (Pubitemid 351670628)
-
(2008)
International Journal of Obesity
, vol.32
, Issue.5
, pp. 863-870
-
-
Kunz, I.1
Meier, M.K.2
Bourson, A.3
Fisseha, M.4
Schilling, W.5
-
57
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent C, Valverde O, Cossu G, Petitet F, Aubert JF, Beslot F, BohmeGA, Imperato A, Pedrazzini T, Roques BP, Vassart G, Fratta W, Parmentier M1999) Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283:401-404
-
(1999)
Science
, vol.283
, pp. 401-404
-
-
Ledent, C.1
Valverde, O.2
Cossu, G.3
Petitet, F.4
Aubert, J.F.5
Beslot, F.6
Bohme, G.A.7
Imperato, A.8
Pedrazzini, T.9
Roques, B.P.10
Vassart, G.11
Fratta, W.12
Parmentier, M.13
-
58
-
-
33845950577
-
Discovery of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1- methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity
-
DOI 10.1021/jm060996+
-
Lin LS, Lanza TJ Jr, Jewell JP, Liu P, Shah SK, Qi H, Tong X, Wang J, Xu SS, Fong TM, Shen CP, Lao J, Xiao JC, Shearman LP, Stribling DS, Rosko K, Strack A, Marsh DJ, Feng Y, Kumar S, Samuel K, Yin W, Van der Ploeg LH, Goulet MT, Hagmann WK2006) Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1- methylpropyl]-2-methyl-2-{[5-trifluoromethyl)pyridin-2-yl]oxy} propanamideMK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity. J Med Chem 49:7584-7587 (Pubitemid 46033647)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.26
, pp. 7584-7587
-
-
Lin, L.S.1
Lanza Jr., T.J.2
Jewell, J.P.3
Liu, F.4
Shah, S.K.5
Qi, H.6
Tong, X.7
Wang, J.8
Xu, S.S.9
Fong, T.M.10
Shen, C.-P.11
Lao, J.12
Xiao, J.C.13
Shearman, L.P.14
Stribling, D.S.15
Rosko, K.16
Strack, A.17
Marsh, D.J.18
Feng, Y.19
Kumar, S.20
Samuel, K.21
Yin, W.22
Van Der Ploeg, L.H.T.23
Goulet, M.T.24
Hagmann, W.K.25
more..
-
59
-
-
13244249625
-
ob mice
-
DOI 10.1038/sj.ijo.0802847
-
Liu YL, Connoley IP, Wilson CA, Stock MJ2005) Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/ Lep(ob) mice. Int J ObesLond) 29:183-187 (Pubitemid 40188413)
-
(2005)
International Journal of Obesity
, vol.29
, Issue.2
, pp. 183-187
-
-
Liu, Y.L.1
Connoley, I.P.2
Wilson, C.A.3
Stock, M.J.4
-
60
-
-
58849116267
-
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist URB447 that reduces feeding and body-weight gain inmice
-
LoVerme J, Duranti A, Tontini A, Spadoni G, MorM, Rivara S, Stella N, Xu C, Tarzia G, Piomelli D2009) Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain inmice. BioorgMed ChemLett 19:639-643
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 639-643
-
-
LoVerme, J.1
Duranti, A.2
Tontini, A.3
Spadoni, G.4
Mor, M.5
Rivara, S.6
Stella, N.7
Xu, C.8
Tarzia, G.9
Piomelli, D.10
-
61
-
-
20044388537
-
Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility
-
DOI 10.1093/molehr/gah130
-
Maccarrone M, Fride E, Bisogno T, Bari M, Cascio MG, Battista N, Finazzi AA, Suris R, Mechoulam R, Di Marzo V2005) Up-regulation of the endocannabinoid system in the uterus of leptin knockoutob/ob) mice and implications for fertility. Mol Hum Reprod 11:21-28 (Pubitemid 40330999)
-
(2005)
Molecular Human Reproduction
, vol.11
, Issue.1
, pp. 21-28
-
-
Maccarrone, M.1
Fride, E.2
Bisogno, T.3
Bari, M.4
Cascio, M.G.5
Battista, N.6
Finazzi Agro, A.7
Suris, R.8
Mechoulam, R.9
Di Marzo, V.10
-
62
-
-
0036682222
-
The endogenous cannabinoid system controls extinction of aversive memories
-
DOI 10.1038/nature00839
-
Marsicano G, Wotjak CT, Azad SC, Bisogno T, Rammes G, Cascio MG, Hermann H, Tang J, Hofmann C, Zieglgansberger W, Di Marzo V, Lutz B2002) The endogenous cannabinoid system controls extinction of aversive memories. Nature 418:530-534 (Pubitemid 34851398)
-
(2002)
Nature
, vol.418
, Issue.6897
, pp. 530-534
-
-
Marsicano, G.1
Wotjak, C.T.2
Azad, S.C.3
Bisogno, T.4
Rammes, G.5
Cascioll, M.G.6
Hermann, H.7
Tang, J.8
Hofmann, C.9
Zieglgansberger, W.10
Di Marzo, V.11
Lutz, B.12
-
63
-
-
33747644061
-
Regulation, function, and dysregulation of endocannabinoids in models of adipose and β-pancreatic cells and in obesity and hyperglycemia
-
DOI 10.1210/jc.2005-2679
-
Matias I, Gonthier MP, Orlando P, Martiadis V, De Petrocellis L, Cervino C, Petrosino S, Hoareau L, Festy F, Pasquali R, Roche R,MajM, Pagotto U,Monteleone P, Di Marzo V2006) Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia. J Clin Endocrinol Metab 91:3171-3180 (Pubitemid 44271774)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.8
, pp. 3171-3180
-
-
Matias, I.1
Gonthier, M.-P.2
Orlando, P.3
Martiadis, V.4
De Petrocellis, L.5
Cervino, C.6
Petrosino, S.7
Hoareau, L.8
Festy, F.9
Pasquali, R.10
Roche, R.11
Maj, M.12
Pagotto, U.13
Monteleone, P.14
Di Marzo, V.15
-
64
-
-
37349102663
-
Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: Insulin and melanocortins
-
DOI 10.1016/j.neuropharm.2007.06.011, PII S0028390807001840, Cannabinoid Signaling in the Nervous system
-
Matias I, Vergoni AV, Petrosino S, Ottani A, Pocai A, Bertolini A, Di Marzo V2008) Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: insulin and melanocortins. Neuropharmacology 54:206-212 (Pubitemid 350299405)
-
(2008)
Neuropharmacology
, vol.54
, Issue.1
, pp. 206-212
-
-
Matias, I.1
Vergoni, A.V.2
Petrosino, S.3
Ottani, A.4
Pocai, A.5
Bertolini, A.6
Di Marzo, V.7
-
65
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
66
-
-
0029012014
-
Identification of an endogenous 2-monoglyceride present in canine gut, that binds to cannabinoid receptors
-
MechoulamR,Ben-Shabat S,Hanus L, Ligumsky M, KaminskiNE, SchatzAR, Gopher A, Almog S, Martin BR, Compton DR1995) Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 50:83-90
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 83-90
-
-
Mechoulam, R.1
Ben-Shabat, S.2
Hanus, L.3
Ligumsky, M.4
Kaminski, N.E.5
Schatz, A.R.6
Gopher, A.7
Almog, S.8
Martin, B.R.9
Compton, D.R.10
-
67
-
-
61649089261
-
Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: Focus on anxiety and depression
-
Moreira FA, Grieb M, Lutz B2009) Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression. Best Pract Res Clin Endocrinol Metab 23:133-144
-
(2009)
Best Pract. Res. Clin. Endocrinol. Metab.
, vol.23
, pp. 133-144
-
-
Moreira, F.A.1
Grieb, M.2
Lutz, B.3
-
68
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
DOI 10.1038/365061a0
-
Munro S, Thomas KL, Abu-Shaar M1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365:61-65 (Pubitemid 23305569)
-
(1993)
Nature
, vol.365
, Issue.6441
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
69
-
-
58149128824
-
Peripheral but not central CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats
-
Nogueiras R, Veyrat-Durebex C, Suchanek PM, Klein M, Tschop J, Caldwell C, Woods SC, Wittmann G, Watanabe M, Liposits Z, Fekete C, Reizes O, Rohner-Jeanrenaud F, Tschop MH2008) Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats. Diabetes 57:2977-2991
-
(2008)
Diabetes
, vol.57
, pp. 2977-2991
-
-
Nogueiras, R.1
Veyrat-Durebex, C.2
Suchanek, P.M.3
Klein, M.4
Tschop, J.5
Caldwell, C.6
Woods, S.C.7
Wittmann, G.8
Watanabe, M.9
Liposits, Z.10
Fekete, C.11
Reizes, O.12
Rohner-Jeanrenaud, F.13
Tschop, M.H.14
-
70
-
-
79953206959
-
Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis
-
O'Hare JD, Zielinski E, Cheng B, Scherer T, Buettner C2011) Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis. Diabetes 60:1055-1062
-
(2011)
Diabetes
, vol.60
, pp. 1055-1062
-
-
O'Hare, J.D.1
Zielinski, E.2
Cheng, B.3
Scherer, T.4
Buettner, C.5
-
71
-
-
25844451605
-
Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide
-
DOI 10.1159/000087925
-
Osei-Hyiaman D, Depetrillo M, Harvey-White J, Bannon AW, Cravatt BF, Kuhar MJ, Mackie K, Palkovits M, Kunos G2005a) Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology 81:273-282 (Pubitemid 41397036)
-
(2005)
Neuroendocrinology
, vol.81
, Issue.4
, pp. 273-282
-
-
Osei-Hyiaman, D.1
Depetrillo, M.2
Harvey-White, J.3
Bannon, A.W.4
Cravatt, B.F.5
Kuhar, M.J.6
Mackie, K.7
Palkovits, M.8
Kunos, G.9
-
72
-
-
20944436157
-
1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
-
DOI 10.1172/JCI200523057
-
Osei-Hyiaman D, Depetrillo M, Pacher P, Liu J, Radaeva S, Batkai S, Harvey-White J, Mackie K, Offertaler L, Wang L, Kunos G2005b) Endocannabinoid activation at hepatic CB(1) receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. JClin Invest 115:1298-1305 (Pubitemid 40629049)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1298-1305
-
-
Osei-Hyiaman, D.1
DePetrillo, M.2
Pacher, P.3
Liu, J.4
Radaeva, S.5
Batkai, S.6
Harvey-White, J.7
Mackie, K.8
Offertaler, L.9
Wang, L.10
Kunos, G.11
-
73
-
-
51349153318
-
Hepatic CB1 receptor is required for development of dietinduced steatosis dyslipidemia and insulin and leptin resistance in mice
-
Osei-Hyiaman D, Liu J, Zhou L, Godlewski G, Harvey-White J, Jeong WI, Batkai S, Marsicano G, Lutz B, Buettner C, Kunos G2008) Hepatic CB1 receptor is required for development of dietinduced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest 118:3160-3169
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3160-3169
-
-
Osei-Hyiaman, D.1
Liu, J.2
Zhou, L.3
Godlewski, G.4
Harvey-White, J.5
Jeong, W.I.6
Batkai, S.7
Marsicano, G.8
Lutz, B.9
Buettner, C.10
Kunos, G.11
-
74
-
-
33748703859
-
The endocannabinoid system as an emerging target of pharmacotherapy
-
DOI 10.1124/pr.58.3.2
-
Pacher P, Batkai S, Kunos G2006) The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 58:389-462 (Pubitemid 44394908)
-
(2006)
Pharmacological Reviews
, vol.58
, Issue.3
, pp. 389-462
-
-
Pacher, P.1
Batkai, S.2
Kunos, G.3
-
75
-
-
32444440208
-
The emerging role of the endocannabinoid system in endocrine regulation and energy balance
-
DOI 10.1210/er.2005-0009
-
Pagotto U, Marsicano G, Cota D, Lutz B, Pasquali R2006) The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev 27:73-100 (Pubitemid 43228239)
-
(2006)
Endocrine Reviews
, vol.27
, Issue.1
, pp. 73-100
-
-
Pagotto, U.1
Marsicano, G.2
Cota, D.3
Lutz, B.4
Pasquali, R.5
-
76
-
-
84884474728
-
Pharmacological actions of cannabinoids
-
Pertwee RG2005) Pharmacological actions of cannabinoids. Handb Exp Pharmacol 168:1-51
-
(2005)
Handb. Exp. Pharmacol.
, vol.168
, pp. 1-51
-
-
Pertwee, R.G.1
-
77
-
-
78650120798
-
International union of basic and clinical pharmacology LXXIX cannabinoid receptors and their ligands: Beyond CB1 and CB2
-
Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, Greasley PJ, Hansen HS, Kunos G, Mackie K, Mechoulam R, Ross RA2010) International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2. Pharmacol Rev 62:588-631
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 588-631
-
-
Pertwee, R.G.1
Howlett, A.C.2
Abood, M.E.3
Alexander, S.P.4
Di Marzo, V.5
Elphick, M.R.6
Greasley, P.J.7
Hansen, H.S.8
Kunos, G.9
Mackie, K.10
Mechoulam, R.11
Ross, R.A.12
-
78
-
-
33744986319
-
Cannabinoid receptor signaling directly inhibits thermogenesis and alters expression of adiponectin and visfatin
-
DOI 10.1055/s-2006-925401
-
Perwitz N, Fasshauer M, Klein J2006) Cannabinoid receptor signaling directly inhibits thermogenesis and alters expression of adiponectin and visfatin. Horm Metab Res 38:356-358 (Pubitemid 43864960)
-
(2006)
Hormone and Metabolic Research
, vol.38
, Issue.5
, pp. 356-358
-
-
Perwitz, N.1
Fasshauer, M.2
Klein, J.3
-
79
-
-
0242268553
-
The molecular logic of endocannabinoid signalling
-
DOI 10.1038/nrn1247
-
Piomelli D2003) The molecular logic of endocannabinoid signalling. Nat Rev Neurosci 4:873-884 (Pubitemid 37351427)
-
(2003)
Nature Reviews Neuroscience
, vol.4
, Issue.11
, pp. 873-884
-
-
Piomelli, D.1
-
80
-
-
32644441249
-
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients - RIO-North America: A randomized controlled trial
-
DOI 10.1001/jama.295.7.761
-
Pi-Sunyer FX, Aronne LJ, Heshmati HM, Devin J, Rosenstock J2006) Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 295:761-775 (Pubitemid 43244304)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.7
, pp. 761-775
-
-
Pi-Sunyer, F.X.1
Aronne, L.J.2
Heshmati, H.M.3
Devin, J.4
Rosenstock, J.5
-
81
-
-
0025720757
-
Recent clinical experience with dronabinol
-
Plasse TF, Gorter RW, Krasnow SH, Lane M, Shepard KV, Wadleigh RG1991) Recent clinical experience with dronabinol. Pharmacol Biochem Behav 40:695-700
-
(1991)
Pharmacol. Biochem. Behav.
, vol.40
, pp. 695-700
-
-
Plasse, T.F.1
Gorter, R.W.2
Krasnow, S.H.3
Lane, M.4
Shepard, K.V.5
Wadleigh, R.G.6
-
82
-
-
77955472298
-
A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: Low-dose study
-
Lond)
-
Proietto J, Rissanen A, Harp JB, Erondu N, Yu Q, Suryawanshi S, Jones ME, Johnson-Levonas AO, Heymsfield SB, Kaufman KD, Amatruda JM2010) A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: low-dose study. Int J ObesLond) 34:1243-1254
-
(2010)
Int. J. Obes.
, vol.34
, pp. 1243-1254
-
-
Proietto, J.1
Rissanen, A.2
Harp, J.B.3
Erondu, N.4
Yu, Q.5
Suryawanshi, S.6
Jones, M.E.7
Johnson-Levonas, A.O.8
Heymsfield, S.B.9
Kaufman, K.D.10
Amatruda, J.M.11
-
83
-
-
77950199353
-
CB1 signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance
-
Quarta C, Bellocchio L, Mancini G, Mazza R, Cervino C, Braulke LJ, Fekete C, Latorre R, Nanni C, Bucci M, Clemens LE, Heldmaier G, Watanabe M, Leste-Lassere T, Maitre M, Tedesco L, Fanelli F, Reuss S, Klaus S, Srivastava RK, Monory K, Valerio A, Grandis A, De Giorgio R, Pasquali R, Nisoli E, Cota D, Lutz B, Marsicano G, Pagotto U2010) CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance. Cell Metab 11:273-285
-
(2010)
Cell Metab.
, vol.11
, pp. 273-285
-
-
Quarta, C.1
Bellocchio, L.2
Mancini, G.3
Mazza, R.4
Cervino, C.5
Braulke, L.J.6
Fekete, C.7
Latorre, R.8
Nanni, C.9
Bucci, M.10
Clemens, L.E.11
Heldmaier, G.12
Watanabe, M.13
Leste-Lassere, T.14
Maitre, M.15
Tedesco, L.16
Fanelli, F.17
Reuss, S.18
Klaus, S.19
Srivastava, R.K.20
Monory, K.21
Valerio, A.22
Grandis, A.23
De Giorgio, R.24
Pasquali, R.25
Nisoli, E.26
Cota, D.27
Lutz, B.28
Marsicano, G.29
Pagotto, U.30
more..
-
84
-
-
0037304290
-
Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice
-
Ravinet Trillou C, Arnone M, Delgorge C, Gonalons N, Keane P, Maffrand JP, Soubrie P2003) Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice. Am J Physiol Regul Integr Comp Physiol 284:R345-R353 (Pubitemid 36120150)
-
(2003)
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
, vol.284
, Issue.2
-
-
Trillou, C.R.1
Arnone, M.2
Delgorge, C.3
Gonalons, N.4
Keane, P.5
Maffrand, J.-P.6
Soubrie, P.7
-
85
-
-
1842866963
-
CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
-
DOI 10.1038/sj.ijo.0802583
-
Ravinet Trillou C, Delgorge C, Menet C, Arnone M, Soubrie P2004) CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int J Obes Relat Metab Disord 28:640-648 (Pubitemid 38491158)
-
(2004)
International Journal of Obesity
, vol.28
, Issue.4
, pp. 640-648
-
-
Ravinet Trillou, C.1
Delgorge, C.2
Menet, C.3
Arnone, M.4
Soubrie, P.5
-
86
-
-
0028129936
-
SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
-
DOI 10.1016/0014-5793(94)00773-X
-
Rinaldi-Carmona M, Barth F, Heaulme M, Shire D, Calandra B, Congy C, Martinez S, Maruani J, Neliat G, Caput D1994) SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett 350:240-244 (Pubitemid 24268029)
-
(1994)
FEBS Letters
, vol.350
, Issue.2-3
, pp. 240-244
-
-
Rinaldi-Carmona, M.1
-
87
-
-
33645786113
-
Human studies of cannabinoids and medicinal cannabis
-
Robson P2005) Human studies of cannabinoids and medicinal cannabis. Handb Exp Pharmacol 168:719-756
-
(2005)
Handb. Exp. Pharmacol.
, vol.168
, pp. 719-756
-
-
Robson, P.1
-
88
-
-
77955625847
-
Rimonabant-mediated changes in intestinal lipid metabolism and improved renal vascular dysfunction in the JCR:LA-cp rat model of prediabetic metabolic syndrome
-
Russell JC, Kelly SE, Diane A, Wang Y, Mangat R, Novak S, Vine DF, Proctor SD2010) Rimonabant-mediated changes in intestinal lipid metabolism and improved renal vascular dysfunction in the JCR:LA-cp rat model of prediabetic metabolic syndrome. Am J Physiol Gastrointest Liver Physiol 299:G507-G516
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.299
-
-
Russell, J.C.1
Kelly, S.E.2
Diane, A.3
Wang, Y.4
Mangat, R.5
Novak, S.6
Vine, D.F.7
Proctor, S.D.8
-
89
-
-
0018922982
-
Antiemetics in patients receiving chemotherapy for cancer. A randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine
-
Sallan SE, Cronin C, Zelen M, Zinberg NE1980) Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine. N Engl J Med 302:135-138 (Pubitemid 10211127)
-
(1980)
New England Journal of Medicine
, vol.302
, Issue.3
, pp. 135-138
-
-
Sallan, S.E.1
Cronin, C.2
Zelen, M.3
Zinberg, N.E.4
-
90
-
-
33751001942
-
Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: A randomised controlled study
-
DOI 10.1016/S0140-6736(06)69571-8, PII S0140673606695718
-
Scheen AJ, Finer N, Hollander P, Jensen MD, van Gaal LF2006) Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study. Lancet 368:1660-1672 (Pubitemid 46048528)
-
(2006)
Lancet
, vol.368
, Issue.9548
, pp. 1660-1672
-
-
Scheen, A.J.1
Finer, N.2
Hollander, P.3
Jensen, M.D.4
Van Gaal, L.F.5
-
91
-
-
0012748901
-
Marihuana smoking in Panama
-
Siler JF, Sheep WL, Bates LB, Clark GF, Cook GW, Smith WH1933) Marihuana smoking in Panama. Mil Surg 73:269-280
-
(1933)
Mil. Surg.
, vol.73
, pp. 269-280
-
-
Siler, J.F.1
Sheep, W.L.2
Bates, L.B.3
Clark, G.F.4
Cook, G.W.5
Smith, W.H.6
-
92
-
-
0031902759
-
SR 141716, a CB1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset
-
Simiand J, Keane M, Keane PE, Soubrie P1998) SR 141716, a CB1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset. Behav Pharmacol 9:179-181 (Pubitemid 28186515)
-
(1998)
Behavioural Pharmacology
, vol.9
, Issue.2
, pp. 179-181
-
-
Simiand, J.1
Keane, M.2
Keane, P.E.3
Soubrie, P.4
-
93
-
-
34547574943
-
Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus
-
DOI 10.1038/sj.bjp.0707313, PII 0707313
-
Soria-Gomez E, Matias I, Rueda-Orozco PE, Cisneros M, Petrosino S, Navarro L, Di Marzo V, Prospero-Garcia O2007) Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus. Br J Pharmacol 151:1109-1116 (Pubitemid 47195529)
-
(2007)
British Journal of Pharmacology
, vol.151
, Issue.7
, pp. 1109-1116
-
-
Soria-Gomez, E.1
Matias, I.2
Rueda-Orozco, P.E.3
Cisneros, M.4
Petrosino, S.5
Navarro, L.6
Di Marzo, V.7
Prospero-Garcia, O.8
-
94
-
-
0030942814
-
Sibutramine: A review of the pharmacology of a novel anti-obesity agent
-
Stock MJ1997) Sibutramine: a review of the pharmacology of a novel anti- obesity agent. Int J Obes Relat Metab Disord 21(Suppl 1):S25-S29 (Pubitemid 27160696)
-
(1997)
International Journal of Obesity
, vol.21
, Issue.SUPPL. 1
-
-
Stock, M.J.1
-
95
-
-
36549015066
-
The endocannabinoid system and gut-brain signalling
-
DOI 10.1016/j.coph.2007.08.008, PII S1471489207001415, Gastrointestinal/Endocrine and metabolic diseases
-
Storr MA, Sharkey KA2007) The endocannabinoid system and gut-brain signalling. Curr Opin Pharmacol 7:575-582 (Pubitemid 350177551)
-
(2007)
Current Opinion in Pharmacology
, vol.7
, Issue.6
, pp. 575-582
-
-
Storr, M.A.1
Sharkey, K.A.2
-
96
-
-
77955286305
-
Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk inmouse models of obesity
-
Tam J, Vemuri VK, Liu J, Batkai S, Mukhopadhyay B, Godlewski G, Osei-Hyiaman D, Ohnuma S, Ambudkar SV, Pickel J, Makriyannis A, Kunos G2010) Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk inmouse models of obesity. JClin Invest 120:2953-2966
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2953-2966
-
-
Tam, J.1
Vemuri, V.K.2
Liu, J.3
Batkai, S.4
Mukhopadhyay, B.5
Godlewski, G.6
Osei-Hyiaman, D.7
Ohnuma, S.8
Ambudkar, S.V.9
Pickel, J.10
Makriyannis, A.11
Kunos, G.12
-
97
-
-
0014959506
-
Marijuana intoxication common experiences
-
Tart CT1970) Marijuana intoxication common experiences. Nature 226:701-704
-
(1970)
Nature
, vol.226
, pp. 701-704
-
-
Tart, C.T.1
-
98
-
-
50949092455
-
Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes
-
Tedesco L, Valerio A, Cervino C, Cardile A, Pagano C, Vettor R, Pasquali R, Carruba MO, Marsicano G, Lutz B, Pagotto U, Nisoli E2008) Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes. Diabetes 57:2028-2036
-
(2008)
Diabetes
, vol.57
, pp. 2028-2036
-
-
Tedesco, L.1
Valerio, A.2
Cervino, C.3
Cardile, A.4
Pagano, C.5
Vettor, R.6
Pasquali, R.7
Carruba, M.O.8
Marsicano, G.9
Lutz, B.10
Pagotto, U.11
Nisoli, E.12
-
99
-
-
78049307571
-
Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue muscle and liver: The role of eNOS p38 MAPK and AMPK pathways
-
Tedesco L,Valerio A, DossenaM, Cardile A, RagniM, Pagano C, Pagotto U, CarrubaMO, Vettor R, Nisoli E2010) Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways. Diabetes 59:2826-2836
-
(2010)
Diabetes
, vol.59
, pp. 2826-2836
-
-
Tedesco, L.1
Valerio, A.2
Dossena, M.3
Cardile, A.4
Ragni, M.5
Pagano, C.6
Pagotto, U.7
Carruba, M.O.8
Vettor, R.9
Nisoli, E.10
-
101
-
-
33746490030
-
1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake
-
DOI 10.1016/j.pbb.2006.06.001, PII S0091305706001730
-
Thornton-Jones ZD, Kennett GA, Benwell KR, Revell DF, Misra A, Sellwood DM, Vickers SP, Clifton PG2006) The cannabinoid CB1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake. Pharmacol Biochem Behav 84:353-359 (Pubitemid 44137303)
-
(2006)
Pharmacology Biochemistry and Behavior
, vol.84
, Issue.2
, pp. 353-359
-
-
Thornton-Jones, Z.D.1
Kennett, G.A.2
Benwell, K.R.3
Revell, D.F.4
Misra, A.5
Sellwood, D.M.6
Vickers, S.P.7
Clifton, P.G.8
-
102
-
-
77956017429
-
Rimonabant for prevention of cardiovascular eventsCRESCENDO: A randomised multicentre placebocontrolled trial
-
Topol EJ, Bousser MG, Fox KA, Creager MA, Després JP, Easton JD, Hamm CW, Montalescot G, Steg PG, Pearson TA, Cohen E, Gaudin C, Job B, Murphy JH, Bhatt DL2010) Rimonabant for prevention of cardiovascular eventsCRESCENDO): a randomised, multicentre, placebocontrolled trial. Lancet 376:517-523
-
(2010)
Lancet
, vol.376
, pp. 517-523
-
-
Topol, E.J.1
Bousser, M.G.2
Fox, K.A.3
Creager, M.A.4
Després, J.P.5
Easton, J.D.6
Hamm, C.W.7
Montalescot, G.8
Steg, P.G.9
Pearson, T.A.10
Cohen, E.11
Gaudin, C.12
Job, B.13
Murphy, J.H.14
Bhatt, D.L.15
-
103
-
-
8744249918
-
1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin
-
DOI 10.1038/sj.bjp.0705968
-
Tucci SA, Rogers EK, Korbonits M, Kirkham TC2004) The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin. Br J Pharmacol 143:520-523 (Pubitemid 39524268)
-
(2004)
British Journal of Pharmacology
, vol.143
, Issue.5
, pp. 520-523
-
-
Tucci, S.A.1
Rogers, E.K.2
Korbonits, M.3
Kirkham, T.C.4
-
104
-
-
17144382751
-
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-Year experience from the RIO-Europe study
-
DOI 10.1016/S0140-6736(05)66374-X
-
van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Roossner S2005) Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365:1389-1397 (Pubitemid 40523733)
-
(2005)
Lancet
, vol.365
, Issue.9468
, pp. 1389-1397
-
-
Van Gaal, L.F.1
Rissanen, A.M.2
Scheen, A.J.3
Ziegler, O.4
Rossner, S.5
-
105
-
-
0030886734
-
Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease
-
DOI 10.1002/(SICI)1099-1166(199709)12:9<913::AID-GPS663>3.0.CO;2-D
-
Volicer L, Stelly M, Morris J, McLaughlin J, Volicer BJ1997) Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease. Int J Geriatr Psychiatry 12:913-919 (Pubitemid 27420571)
-
(1997)
International Journal of Geriatric Psychiatry
, vol.12
, Issue.9
, pp. 913-919
-
-
Volicer, L.1
Stelly, M.2
Morris, J.3
McLaughlin, J.4
Volicer, B.J.5
-
106
-
-
78649954020
-
A randomized trial of lifestyle modification and taranabant for maintaining weight loss achieved with a low-calorie diet
-
Wadden TA, Fujioka K, Toubro S, Gantz I, Erondu NE, Chen M, Suryawanshi S, Carofano W, Johnson-Levonas AO, Shapiro DR, Kaufman KD, Heymsfield SB, Amatruda JM2010) A randomized trial of lifestyle modification and taranabant for maintaining weight loss achieved with a low-calorie diet. ObesitySilver Spring) 18:2301-2310
-
(2010)
ObesitySilver Spring
, vol.18
, pp. 2301-2310
-
-
Wadden, T.A.1
Fujioka, K.2
Toubro, S.3
Gantz, I.4
Erondu, N.E.5
Chen, M.6
Suryawanshi, S.7
Carofano, W.8
Johnson-Levonas, A.O.9
Shapiro, D.R.10
Kaufman, K.D.11
Heymsfield, S.B.12
Amatruda, J.M.13
-
107
-
-
0142120539
-
Rise in morning saliva cortisol is associated with abdominal obesity in men: A preliminary report
-
Wallerius S, Rosmond R, Ljung T, Holm G, Bjorntorp P2003) Rise in morning saliva cortisol is associated with abdominal obesity in men: a preliminary report. J Endocrinol Invest 26:616-619 (Pubitemid 37270690)
-
(2003)
Journal of Endocrinological Investigation
, vol.26
, Issue.7
, pp. 616-619
-
-
Wallerius, S.1
Rosmond, R.2
Ljung, T.3
Holm, G.4
Bjorntorp, P.5
-
108
-
-
76249132039
-
The abuse potential of the synthetic cannabinoid nabilone
-
Ware MA, St Arnaud-Trempe E2010) The abuse potential of the synthetic cannabinoid nabilone. Addiction 105:494-503
-
(2010)
Addiction
, vol.105
, pp. 494-503
-
-
Ware, M.A.1
St Arnaud-Trempe, E.2
-
109
-
-
0242492997
-
N-3 Polyunsaturated fatty acid (PUFA) deficiency elevates and n-3 PUFA enrichment reduces brain 2-arachidonoylglycerol level in mice
-
DOI 10.1016/S0952-3278(03)00056-5
-
Watanabe S, Doshi M, Hamazaki T2003) n-3 Polyunsaturated fatty acidPUFA) deficiency elevates and n-3 PUFA enrichment reduces brain 2-arachidonoylglycerol level in mice. Prostaglandins Leukot Essent Fatty Acids 69:51-59 (Pubitemid 37421501)
-
(2003)
Prostaglandins Leukotrienes and Essential Fatty Acids
, vol.69
, Issue.1
, pp. 51-59
-
-
Watanabe, S.1
Doshi, M.2
Hamazaki, T.3
-
110
-
-
0032936642
-
Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors
-
DOI 10.1007/s002130050953
-
Williams CM, Kirkham TC1999) Anandamide induces overeating: mediation by central cannabinoidCB1) receptors. PsychopharmacologyBerl) 143:315-317 (Pubitemid 29204987)
-
(1999)
Psychopharmacology
, vol.143
, Issue.3
, pp. 315-317
-
-
Williams, C.M.1
Kirkham, T.C.2
-
111
-
-
0036607403
-
9-THC and anandamide
-
DOI 10.1016/S0031-9384(02)00725-4, PII S0031938402007254
-
Williams CM, Kirkham TC2002) Observational analysis of feeding induced by Delta9-THC and anandamide. Physiol Behav 76:241-250 (Pubitemid 34607232)
-
(2002)
Physiology and Behavior
, vol.76
, Issue.2
, pp. 241-250
-
-
Williams, C.M.1
Kirkham, T.C.2
-
112
-
-
0035967145
-
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses
-
DOI 10.1038/35069076
-
Wilson RI, Nicoll RA2001) Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses. Nature 410:588-592 (Pubitemid 32267203)
-
(2001)
Nature
, vol.410
, Issue.6828
, pp. 588-592
-
-
Wilson, R.I.1
Nicoll, R.A.2
-
113
-
-
34447635408
-
Distribution of type 1 cannabinoid receptor (CB1)-immunoreactive axons in the mouse hypothalamus
-
DOI 10.1002/cne.21383
-
Wittmann G, Deli L, Kallo I, Hrabovszky E, Watanabe M, Liposits Z, Fekete C2007) Distribution of type 1 cannabinoid receptorCB1)-immunoreactive axons in the mouse hypothalamus. J Comp Neurol 503:270-279 (Pubitemid 47091706)
-
(2007)
Journal of Comparative Neurology
, vol.503
, Issue.2
, pp. 270-279
-
-
Wittmann, G.1
Deli, L.2
Kallo, I.3
Hrabovszky, E.4
Watanabe, M.5
Liposits, Z.6
Fekete, C.7
-
114
-
-
0033545866
-
Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
-
DOI 10.1073/pnas.96.10.5780
-
Zimmer A, Zimmer AM, Hohmann AG, Herkenham M, Bonner TI1999) Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc Natl Acad Sci USA 96:5780-5785 (Pubitemid 29234695)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.10
, pp. 5780-5785
-
-
Zimmer, A.1
Zimmer, A.M.2
Hohmann, A.G.3
Herkenham, M.4
Bonner, T.I.5
|