Astrocyte mediated protection of fetal cerebral cortical neurons from rotenone and paraquat

Environmental Toxicology and Pharmacology

Volumn 33, Issue 2, 2012, Pages 353-360

  Rathinam, Mary Latha ^a   Watts, Lora Talley ^b   Narasimhan, Madhusudhanan ^a   Riar, Amanjot Kaur ^a   Mahimainathan, Lenin ^a   Henderson, George I ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Glutamyl cycle; Astrocytes; Glutathione; Neurons; Paraquat; Rotenone

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; PARAQUAT; ROTENONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL CULTURE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL SURVIVAL; CELL VIABILITY; CHEMICAL ANALYSIS; COCULTURE; CONTROLLED STUDY; EMBRYO; FLOW CYTOMETRY; HOMEOSTASIS; HYDROLYSIS; IN VITRO STUDY; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD13; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; COCULTURE TECHNIQUES; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-GLUTAMYLTRANSFERASE; GLUTATHIONE; HERBICIDES; INSECTICIDES; NEURONS; OXIDATIVE STRESS; PARAQUAT; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; ROTENONE; TIME FACTORS;

RATTUS;

EID: 84856327256     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2011.12.027     Document Type: Article

References (43)

1. Bandeira F., Lent R., Herculano-Houzel S. Changing numbers of neuronal and non-neuronal cells underlie postnatal brain growth in the rat. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(33):14108-14113.
2. Betarbet R., Sherer T.B., MacKenzie G., Garcia-Osuna M., Panov A.V., Greenamyre J.T. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 2000, 3(12):1301-1306.
3. Brooks A.I., Chadwick C.A., Gelbard H.A., Cory-Slechta D.A., Federoff H.J. Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss. Brain Res. 1999, 823(1-2):1-10.
4. Choi W.S., Abel G., Klintworth H., Flavell R.A., Xia Z. JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron death. J. Neuropathol. Exp. Neurol. 2010, 69(5):511-520.
5. Cooper A. Glutathione in the brain disorders of glutathione metabolism. The Molecular and Genetic Basis of Neurological Disease 1997, 1195-1230. Butterworth-Heinemann, Boston. R.N. Rosenberg, S.B. Prusiner, S. DiMauro, R.I. Barchi, L.M. Kunk (Eds.).
6. Corasaniti M.T., Strongoli M.C., Rotiroti D., Bagetta G., Nistico G. Paraquat: a useful tool for the in vivo study of mechanisms of neuronal cell death. Pharmacol. Toxicol. 1998, 83(1):1-7.
7. Dawson T.M., Dawson V.L. Molecular pathways of neurodegeneration in Parkinson's disease. Science 2003, 302(5646):819-822.
8. Dringen R., Gutterer J.M., Hirrlinger J. Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur. J. Biochem. 2000, 267(16):4912-4916.
9. Dringen R., Kussmaul L., Gutterer J.M., Hirrlinger J., Hamprecht B. The glutathione system of peroxide detoxification is less efficient in neurons than in astroglial cells. J. Neurochem. 1999, 72(6):2523-2530.
10. Dringen R., Pfeiffer B., Hamprecht B. Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione. J. Neurosci. 1999, 19(2):562-569.
11. Dutton G.R. Isolation culture and use of viable central nervous system perikarya. Methods in Neuroscience 1990, 87-102. Academic Press, New York. P.M. Conn (Ed.).
12. Fernandez-Checa J.C., Kaplowitz N. The use of monochlorobimane to determine hepatic GSH levels and synthesis. Anal. Biochem. 1990, 190(2):212-219.
13. Ferrante R.J., Schulz J.B., Kowall N.W., Beal M.F. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Res. 1997, 753(1):157-162.
14. Johnson D.A., Andrews G.K., Xu W., Johnson J.A. Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice. J. Neurochem. 2002, 81(6):1233-1241.
15. Ju C., Yoon K.N., Oh Y.K., Kim H.C., Shin C.Y., Ryu J.R., Ko K.H., Kim W.K. Synergistic depletion of astrocytic glutathione by glucose deprivation and peroxynitrite: correlation with mitochondrial dysfunction and subsequent cell death. J. Neurochem. 2000, 74(5):1989-1998.
16. Jung Y., Surh Y. Oxidative DNA damage and cytotoxicity induced by copper-stimulated redox cycling of salsolinol, a neurotoxic tetrahydroisoquinoline alkaloid. Free Radic. Biol. Med. 2001, 30(12):1407-1417.
17. Kim D.W., Kim S.Y., Lee S.H., Lee Y.P., Lee M.J., Jeong M.S., Jang S.H., Park J., Lee K.S., Kang T.C., Won M.H., Cho S.W., Kwon O.S., Eum W.S., Choi S.Y. Protein transduction of an antioxidant enzyme: subcellular localization of superoxide dismutase fusion protein in cells. BMB Rep. 2008, 41(2):170-175.
18. Kranich O., Dringen R., Sandberg M., Hamprecht B. Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: preference for cystine. Glia 1998, 22(1):11-18.
19. Kranich O., Hamprecht B., Dringen R. Different preferences in the utilization of amino acids for glutathione synthesis in cultured neurons and astroglial cells derived from rat brain. Neurosci. Lett. 1996, 219(3):211-214.
20. Lapointe N., St-Hilaire M., Martinoli M.G., Blanchet J., Gould P., Rouillard C., Cicchetti F. Rotenone induces non-specific central nervous system and systemic toxicity. FASEB J. 2004, 18(6):717-719.
21. Maffi S.K., Rathinam M.L., Cherian P.P., Pate W., Hamby-Mason R., Schenker S., Henderson G.I. Glutathione content as a potential mediator of the vulnerability of cultured fetal cortical neurons to ethanol-induced apoptosis. J. Neurosci. Res. 2008, 86(5):1064-1076.
22. Manning-Bog A.B., McCormack A.L., Li J., Uversky V.N., Fink A.L., Di Monte D.A. The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein. J. Biol. Chem. 2002, 277(3):1641-1644.
23. Manning-Bog A.B., McCormack A.L., Purisai M.G., Bolin L.M., Di Monte D.A. Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration. J. Neurosci. 2003, 23(8):3095-3099.
24. McCarthy K.D., de Vellis J. Preparation of separate astroglial and aligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol. 1980, 85:890-902.
25. McCormack A.L., Di Monte D.A. Effects of L-dopa and other amino acids against paraquat-induced nigrostriatal degeneration. J. Neurochem. 2003, 85(1):82-86.
26. Mollace V., Iannone M., Muscoli C., Palma E., Granato T., Rispoli V., Nistico R., Rotiroti D., Salvemini D. The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic. Neurosci. Lett. 2003, 335(3):163-166.
27. Narasimhan M., Mahimainathan L., Rathinam M.L., Riar A.K., Henderson G.I. Overexpression of Nrf2 protects cerebral cortical neurons from ethanol-induced apoptotic death. Mol. Pharmacol. 2011, 80(6):1-12.
28. Ramachandran V., Watts L.T., Maffi S.K., Chen J., Schenker S., Henderson G. Ethanol-induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons. J. Neurosci. Res. 2003, 74(4):577-588.
29. Rathinam M.L., Watts L.T., Stark A.A., Mahimainathan L., Stewart J., Schenker S., Henderson G.I. Astrocyte control of fetal cortical neuron glutathione homeostasis: up-regulation by ethanol. J. Neurochem. 2006, 96(5):1289-1300.
30. Rohlmann A., Wolff J.R. Subcellular topography and plasticity of gap junction distribution on astrocytes. Neuroscience Intelligence 1996, 175-189. Springer, Austin. D.C. Spray, R. Dermietzel (Eds.).
31. Sagara J.I., Miura K., Bannai S. Maintenance of neuronal glutathione by glial cells. J. Neurochem. 1993, 61(5):1672-1676.
32. Schmuck G., Rohrdanz E., Tran-Thi Q.H., Kahl R., Schluter G. Oxidative stress in rat cortical neurons and astrocytes induced by paraquat in vitro. Neurotox. Res. 2002, 4(1):1-13.
33. Schneider J.S., Yuwiler A., Markham C.H. Selective loss of subpopulations of ventral mesencephalic dopaminergic neurons in the monkey following exposure to MPTP. Brain Res. 1987, 411(1):144-150.
34. Schulz J.B., Lindenau J., Seyfried J., Dichgans J. Glutathione, oxidative stress and neurodegeneration. Eur. J. Biochem. 2000, 267(16):4904-4911.
35. Sherer T.B., Betarbet R., Testa C.M., Seo B.B., Richardson J.R., Kim J.H., Miller G.W., Yagi T., Matsuno-Yagi A., Greenamyre J.T. Mechanism of toxicity in rotenone models of Parkinson's disease. J. Neurosci. 2003, 23(34):10756-10764.
36. Sherer T.B., Kim J.H., Betarbet R., Greenamyre J.T. Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation. Exp. Neurol. 2003, 179(1):9-16.
37. Shih A.Y., Johnson D.A., Wong G., Kraft A.D., Jiang L., Erb H., Johnson J.A., Murphy T.H. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J. Neurosci. 2003, 23(8):3394-3406.
38. Suntres Z.E. Role of antioxidants in paraquat toxicity. Toxicology 2002, 180(1):65-77.
39. Thiruchelvam M., Richfield E.K., Baggs R.B., Tank A.W., Cory-Slechta D.A. The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease. J. Neurosci. 2000, 20(24):9207-9214.
40. Wang X.F., Cynader M.S. Astrocytes provide cysteine to neurons by releasing glutathione. J. Neurochem. 2000, 74(4):1434-1442.
41. Watts L.T., Rathinam M.L., Schenker S., Henderson G.I. Astrocytes protect neurons from ethanol-induced oxidative stress and apoptotic death. J. Neurosci. Res. 2005, 80(5):655-666.
42. Weiss B., Amler S., Amler R.W. Pesticides. Pediatrics 2004, 113(4 Suppl.):1030-1036.
43. Wilson J.X. Antioxidant defense of the brain: a role for astrocytes?. Can. J. Physiol. Pharmacol. 1997, 75(10-11):1149-1163.