Activation of cd40 with platelet derived cd154 promotes reactive oxygen species dependent death of human hepatocytes during hypoxia and reoxygenation

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Bhogal, Ricky H ^a   Weston, Christopher J ^a   Curbishley, Stuart M ^a   Adams, David H ^a   Afford, Simon C ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; DICHLOROFLUORESCEIN; FAS LIGAND; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; RECOMBINANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXYGEN;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL HYPOXIA; CELL ISOLATION; CELL LABELING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTRACELLULAR SIGNALING; LIVER CELL; LIVER NECROSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REOXYGENATION; THROMBOCYTE FUNCTION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; GENE EXPRESSION REGULATION; INFLAMMATION; INTRACELLULAR SPACE; METABOLISM; NECROSIS; PATHOLOGY; REPERFUSION INJURY; SOLUBILITY; THROMBOCYTE;

ANTIGENS, CD40; APOPTOSIS; BLOOD PLATELETS; CD40 LIGAND; CELL HYPOXIA; EPITHELIAL CELLS; FAS LIGAND PROTEIN; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; INFLAMMATION; INTRACELLULAR SPACE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NADP; NADPH OXIDASE; NECROSIS; OXYGEN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SOLUBILITY;

EID: 84856300468     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030867     Document Type: Article

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