Susceptibility of murine periportal hepatocytes to hypoxia-reoxygenation: Role for NO and Kupffer cell-derived oxidants

Hepatology

Volumn 39, Issue 6, 2004, Pages 1544-1552

  Taniai, Hisashi ^a   Hines, Ian N ^a   Bharwani, Sulaiman ^b   Maloney, Ronald E ^a   Nimura, Yuji ^d   Gao, Bifeng ^c   Flores, Sonia C ^c   McCord, Joe M ^c   Grisham, Matthew B ^a   Aw, Tak Yee ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b Louisiana State University School of Medicine Shreveport   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GADOLINIUM CHLORIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL HYPOXIA; CELL PROTECTION; CONTROLLED STUDY; ENZYME RELEASE; HISTOPATHOLOGY; KUPFFER CELL; LIVER CELL DAMAGE; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REOXYGENATION; REPERFUSION INJURY;

ANIMALS; CELL HYPOXIA; DIGITONIN; HEPATOCYTES; KUPFFER CELLS; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE; OXYGEN;

EID: 2542615327     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20217     Document Type: Article

References (36)

1. Fan C, Zwacka RM, Engelhardt JF. Therapeutic approaches for ischemic/reperfusion injury in the liver. J Mol Med 1999;77:577-592.
2. Jaeschke H. Mechanisms of reperfusion injury after warm ischemia of the liver. J Hepatobiliary Pancreat Surg. 1998;5:402-408.
3. Muller MJ, Vollmar B, Friedl HP, Menger MD. Xanthine oxidase and superoxide radicals in portal triad crossclamping-induced microvascular reperfusion injury of the liver. Free Radic Biol Med 1996;21:189-197.
4. Rauen U, Viebahn R, Lauchart W, de Groot H. The potential role of reactive oxygen species in liver ischemia/reperfusion injury following liver surgery. Hepatogastroenterology. 1994;41:333-336.
5. Scales WE, Campbell DA, Green ME, Remick DG. Hepatic ischemia/ reperfusion injury: importance of oxidant/tumor necrosis factor interactions. Am J Physiol 1994;267:G1122-G1127.
6. Lee VM, Cameron RG, Archer MC. Zonal location of compensatory hepatocyte proliferation following chemically induced hepatotoxicity in rats and humans. Toxicol Pathol 1998;26:621-627.
7. Quistorff B. Gluconeogenesis in periportal and perivenous hepatocytes of rat liver, isolated by a new high-yield digitonin/collagenase perfusion technique. Biochem J 1985;229:221-226.
8. Jungermann K, Kietzmann T. Oxygen: modulator of metabolic zonation and disease of the liver. HEPATOLOGY 2000;32:255-260.
9. Lindros KO, Penttila KE. Digitonin-collagenase perfusion for efficient separation of periportal or perivenous hepatocytes. Biochem J 1985;228:757-760.
10. Suematzu M, Suzuki H, Ishii H, Kato S, Yanagisawa T, Asako H, et al. Early midzonal oxidative stress preceding cell death in hypoperfused rat liver. Gastroenterology 1992;103:994-1001.
11. Suzuki H, Suematzu M, Ishii H, Kato S, Miki H, Mori M, et al. Prostagladin E1 abrogates early reductive stress and zone-specific paradoxical oxidative injury in hypoperfused rat liver. J Clin Invest 1994;93:155-164.
12. Kato Y, Tanaka J, Koyama K. Intralobular heterogeneity of oxidative stress and cell death in ischemia-reperfused rat liver. J Surg Res 2001;95:99-106.
13. Jaeschke H, Farhood A. Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver. Am J Physiol 1991;260: G355-G362.
14. Colletti LM, Remick DG, Burtch GD, Kunkel SL, Strieter RM, Campbell DA. Role of tumor necrosis factor-alpha in the pathophysiological alterations after ischemia/reperfusion injury in the rat. J Clin Invest 1990;85:1936-1943.
15. Horie Y, Wolf R, Russell J, Shanley TP, Granger DN. Role of Kupffer cells in gut ischemia/reperfusion-induced hepatic microvascular dysfunction in mice. HEPATOLOGY 1997;26:1499-1505.
16. Gao W, Yakei Y, Marzi I, Linden KA, Caldwell-Kenkel JC, Currin RT, et al. Carolina rinse solution-a new strategy to increase survival time after orthotopic liver transplantation in the rat. Transplantation 1991;52:417-424.
17. Jaeschke H, Baustista AP, Spolarics Z, Spitzer JJ. Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia. Free Radic Res Commun 1991;15:277-284.
18. Baustista AP, Meszaros K, Bojta J, Spitzer JJ. Superoxide anion generation in the liver during the early stage of endotoxemia in rats. J Leukoc Biol 1990;49:123-128.
19. Taniai H, Suematsu M, Suzuki T, Norimizu S, Hori R, Ishimura Y, et al. Endothelin B receptor-mediated protection against anoxia-reoxygenation injury in perfused rat liver: nitric oxide-dependent and -independent mechanisms. HEPATOLOGY 2001;33:894-901.
20. Suematsu M, Goda N, Sano T, Kashiwagi S, Egawa T, Shinoda Y, et al. Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver. J Clin Invest 1995;96:2431-2437.
21. Jaeschke H, Smith CV, Mitchell JR. Hypoxic damage generates reactive oxygen species in isolated perfused rat liver. Biochem Biophys Res Commun 1988;150:568-574.
22. Imamura K, Tanaka T. Pyruvate kinase isozymes from rat. Meth Enzymol 1982;90:150-165.
23. Kubes P, Suzuki M, Granger DN. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991;88:4651-4655.
24. Jungermann K. Metabolic zonation of carbohydrate metabolism in the liver. In: Lemasters JJ, Hackenbrock CR, Thurman RG, eds. Integration of Mitochondrial Function. New York: Plenum Press, 1988:561-579.
25. Bergamini S, Rota C, Canali R, Staffieri M, Daneri F, Bini A, et al. N-acetylcysteine inhibits in vivo nitric oxide production by inducible nitric oxide synthase. Nitric Oxide 2001;5:349-360.
26. Gao B, Flores SC, Leff JA, Bose SK, McCord JM. Synthesis and anti-inflammatory activity of a chimeric recombinant superoxide dismutase: SOD2/3. Am J Physiol Lung Cell Mol Physiol 2003;284:L917-L925.
27. Spolarics Z. Endotoxemia, pentose cycle, and the oxidant/antioxidant balance in the hepatic sinusoid. J Leukoc Biol 1998;63:534-541.
28. Hines IN, Harada H, Bharwani S, Pavlick KP, Hoffman JM, Grisham MB. Enhanced post-ischemic liver injury in iNOS-deficient mice: a cautionary note. Biochem Biophys Res Commun 2001;284:972-976.
29. Kawachi S, Hines IN, Laroux FS, Hoffman J, Bharwani S, Gray L, et al. Nitric oxide synthase and postischemic liver injury. Biochem Biophys Res Commun 2000;276:851-854.
30. Wang Y, Lawson JA, Jaeschke H. Differential effect of 2-aminoethylisothiourea, an inhibitor of the inducible nitric oxide synthase, on microvascular blood flow and organ injury in models of hepatic ischemia-reperfusion and endotoxemia. Shock 1998;10:20-25.
31. Shiomi M, Wakabayashi Y, Sano T, Shinoda Y, Nimura Y, Ishimura Y, et al. Nitric oxide suppression reversibly attenuates mitochondrial dysfunction and cholestasis in endotoxemic rat liver. HEPATOLOGY 1998;27:108-115.
32. Sonin NV, Garcia-Pagan JC, Nakanishi K, Zhang JX, Clemens MG. Patterns of vasoregulatory expression in the liver response to ischemia/reperfusion and endotoxemia. Shock 1999;11:175-179.
33. MacMicking JD, Nathan C, Hom G, Chartrain N, Fletcher DS, Trumbauer M, et al. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 1995;81:641-650.
34. Cuzzocrea S, Mazzon E, Dugo L, Barbera A, Centorrino T, Ciccolo A, et al. Inducible nitric oxide synthase knockout mice exhibit resistance to the multiple organ failure induced by zymosan. Shock 2001;16:51-58.
35. Lorente JA, Tejedor C, Delgado MA, Fernandez-Segoviano P, Jara N, Tobalina R, et al. Hemodynamic, biochemical and morphological changes induced by aminoguanidine in normal and septic sheep. Intensive Care Med 2000;26:1670-1680.
36. Lee VM, Cameron RG, Archer MC. Zonal location of compensatory hepatocyte proliferation following chemically induced hepatotoxicity in rats and humans. Toxicol Pathol 1998;26:621-627.