Blockade of the Fas/Fas ligand interaction suppresses hepatocyte apoptosis in ischemia-reperfusion rat liver

Apoptosis

Volumn 13, Issue 8, 2008, Pages 1013-1021

  Nakajima, Hiroo ^a   Mizuta, Naruhiko ^a   Fujiwara, Ikuya ^a   Sakaguchi, Koichi ^a   Ogata, Hiromitsu ^b   Magae, Junji ^c   Yagita, Hideo ^d   Koji, Takehiko ^e  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^c CENTRAL RESEARCH INSTITUTE OF ELECTRIC POWER INDUSTRY   (Japan)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Fas; Fas ligand; Hepatocyte; Ischemia reperfusion

Indexed keywords

FAS ANTIBODY; FAS LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; IMMUNOCOMPETENT CELL; LIVER CELL; LIVER CELL DAMAGE; LIVER ISCHEMIA; MACROPHAGE; MALE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT;

ANIMALS; ANTIBODIES; ANTIGENS, CD95; APOPTOSIS; CHEMOTAXIS, LEUKOCYTE; FAS LIGAND PROTEIN; HEPATOCYTES; LIVER; LIVER FAILURE; MACROPHAGES; MALE; RATS; RATS, WISTAR; REPERFUSION INJURY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS;

RATTUS;

EID: 47349122695     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0234-5     Document Type: Article

References (56)

1. H Bismuth D Castaing OJ Garden 1989 Major hepatic resection under total vascular exclusion Ann Surg 210 13 19 10.1097/00000658-198907000-00002
2. T Starzl R Bell R Beart R Putnam 1975 Hepatic trisegmentectomy and other liver resections Surg Gynecol Obstet 141 429 437
3. PA Clavien PRC Harvey SM Strasberg 1992 Preservation and reperfusion injury allografts: overview and synthesis of current studies Transplantation 53 957 978 10.1097/00007890-199205000-00001
4. AB Lentsch A Kato H Yoshidome KM McMasters MJ Edwards 2000 Inflammatory mechanisms and therapeutic strategies for worm hepatic ischemia/reperfusion injury Hepatology 32 169 173 10.1053/jhep.2000.9323
5. RF Schwabe DA Brenner 2006 Mechanisms of liver injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways Am J Physiol Gastrointest Liver Physiol 290 G583 G589 10.1152/ajpgi.00422.2005
6. H Jaeschke CW Smith 1997 Mechanisms of neutrophil induced parenchymal cell injury J Leukoc Biol 61 647 653
7. HJ Schlayer H Laaff T Peters 1988 Involvement of tumor necrosis factor in endotoxin-triggered neutrophils adherence to sinusoidal endothelial cells of mouse liver and its modulation in acute phase J Hepatol 7 239 249 10.1016/S0168-8278(88)80488-4
8. CL Edelstein ED Wieder MM Yaqoob 1995 The role of cysteine proteases in hypoxia-induced rat renal proximal tubular injury Proc Natl Acad Sci USA 92 7662 7666 10.1073/pnas.92.17.7662
9. JC Nichols SF Bronk GJ Gores 1994 Inhibition of nonlysosomal calcium-dependent proteolysis by glycine during anoxic injury of rat hepatocytes Gastroenterology 106 168 176
10. V Kohli W Gao CA Camargo PA Clavien 1997 Calpain is a mediator of preservation: reperfusion injury in rat liver transplantation Proc Natl Acad Sci USA 94 9354 9359 10.1073/pnas.94.17.9354
11. HI Aguilar JL Steers RH Weisner RAF Krom GJ Gores 1997 Enhanced liver calpain protease activity is a risk factor for dysfunction of human liver allograft Transplantation 63 612 614 10.1097/00007890-199702270-00023
12. K Vivek S Markus FM John CB Rex AC Pierre 1999 Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver Transplantation 67 1099 1105 10.1097/00007890-199904270-00003
13. SQ Li LJ Liang JH Huang Z Li 2003 Hepatocyte apoptosis induced by hepatic ischemia-reperfusion injury in cirrhotic rats Hepatobiliary Pancreat Dis Int 2 102 105
14. HA Rudiger PA Clavien 2002 Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver Gastroenterology 122 202 210 10.1053/gast.2002.30304
15. RA Gottlieb KO Burleson RA Kloner BM Babior RL Engler 1994 Reperfusion injury induces apoptosis in rabbit cardiomyocytes J Clin Invest 94 1621 1628 10.1172/JCI117504
16. N Itoh S Yonehara A Ishii 1991 The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis Cell 66 233 243 10.1016/0092-8674(91)90614-5
17. T Suda T Takahashi P Golstein S Nagata 1993 Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family Cell 75 1169 1178 10.1016/0092-8674(93)90326-L
18. N Kayagaki A Kawasaki T Ebata 1995 Metalloproteinase-mediated release of human Fas ligand J Exp Med 182 1777 1783 10.1084/jem.182.6.1777
19. KL Serrao JD Fortenberry ML Owens FL Harris LA Brown 2001 Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand Am J Physiol Lung Cell Mol Physiol 280 L298 L305
20. WC Liles PA Kiener JA Ledbetter A Aruffo SJ Klebanoff 1996 Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils J Exp Med 184 429 440 10.1084/jem.184.2.429
21. PA Kiener PM Davis BM Rankin 1997 Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation J Immunol 159 1594 1598
22. S Nagata 1997 Apoptosis by death factor Cell 88 355 365 10.1016/S0092-8674(00)81874-7
23. FC Kischkel S Hellbardt I Behrmann 1995 Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor EMBO J 14 5579 5588
24. JP Medema C Scaffidi FC Kischkel 1997 FLICE is activated by association with the CD95 death-inducing signaling complex (DISC) EMBO J 16 2794 2804 10.1093/emboj/16.10.2794
25. MO Hengartner 2000 The biochemistry of apoptosis Nature 407 770 776 10.1038/35037710
26. SA Susin HK Lorenzo N Zamzami 1999 Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 441 446 10.1038/17135
27. P Li D Nijhawan I Budihardjo SM Srinivasula M Ahmad ES Alnemri 1997 Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 479 489 10.1016/S0092-8674(00)80434-1
28. D Kagi F Vignaux B Ledermann 1994 Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity Science 265 528 530 10.1126/science.7518614
29. B Lowin M Hahne C Mattmann J Tschopp 1994 Cytotoxic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways Nature 370 650 652 10.1038/370650a0
30. I Rodriguez K Matsuura C Ody S Nagata P Vassalli 1996 Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death J Exp Med 184 2067 2072 10.1084/jem.184.5.2067
31. S Eguchi S Matsuzaki H Fujioka T Koji Y Higami T Kanematsu 1998 The Fas/Fas-ligand system function in hepatocytes in the early stage of fulminant hepatic failure in rats Hepatol Res 11 103 114 10.1016/S1386-6346(98)00020-5
32. T Tordjmann A Soulie C Guettier 1998 Perforin and granzyme B lytic protein expression during chronic viral and autoimmune hepatitis Liver 18 391 397
33. MT Lin SA Stohlman DR Hinton 1997 Mouse hepatitis virus is cleared from the central nervous system of mice lacking perforin-mediated cytolysis J Virol 71 383 391
34. Y Watanabe M Morita T Akaike 1996 Concanavalin A induces perforin-mediated but not Fas-mediated hepatic injury Hepatology 24 702 710 10.1002/hep.510240338
35. Y Kitamura S Hashimoto N Mizuta 2001 Fas/FasL-dependent apoptosis of alveolar cells after lipopolysaccharide-induced lung injury in mice Am J Respir Crit Care Med 163 762 769
36. KH Albertine MF Soulier Z Wang 2002 Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome Am J Pathol 161 1783 1796
37. S Hashimoto A Kobayashi K Kooguchi Y Kitamura H Onodera H Nakajima 2000 Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome Am J Respir Crit Care Med 161 237 243
38. M Mizuta H Nakajima N Mizuta 2008 Fas ligand released by activated monocytes causes apoptosis of lung epithelial cells in human acute lung injury model in vitro Biol Pharm Bull 31 386 390 10.1248/bpb.31.386
39. N Hakuno T Koji T Yano 1996 PKFas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia Endocrinology 137 1938 1948 10.1210/en.137.5.1938
40. T Koji Y Hishikawa H Ando Y Nakanishi N Kobayashi 2001 Expression of Fas and Fas ligand in normal and ischemia-reperfusion testes: involvement of the Fas system in the induction of germ cell apoptosis in the damaged mouse testis Biol Reprod 64 946 954 10.1095/biolreprod64.3.946
41. N Kayagaki N Yamaguchi F Nagao 1997 Polymorphism of murine Fas ligand that affects the biological activity Proc Natl Acad Sci USA 94 3914 3919 10.1073/pnas.94.8.3914
42. K Ejima T Koji D Tsuruta H Nanri M Kashimura M Ikeda 2000 Induction of apoptosis in placentas of pregnant mice exposed to lipopolysaccharides: possible involvement of Fas/Fas ligand system Biol Reprod 62 178 185 10.1095/biolreprod62.1.178
43. Y Seko N Kayagaki K Seino H Yagita K Okumura R Nagai 2002 Role of Fas/FasL pathway in the activation of infiltrating cells in murine acute myocarditis caused by Coxsackievirus B3 J Am Coll Cardiol 39 1399 1403 10.1016/S0735-1097(02)01776-X
44. K Seino K Iwabuchi N Kayagaki 1998 Chemotactic activity of soluble Fas ligand against phagocytes J Immunol 161 4484 4488
45. H Shibuya N Ohkohchi S Tsukamoto S Satomi 1997 Tumor necrosis factor-induced, superoxide-mediated neutrophils accumulation in cold ischemia/reperfused rat liver Hepatology 26 113 120 10.1002/hep.510260115
46. HA Rudiger PA Clavien 2002 Tumor necrosis factor a, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver Gastroenterology 122 202 210 10.1053/gast.2002.30304
47. WC Stephen DT Pauline GR Daniel ES Wendy LK Steven 1991 In vivo biologic and immunohistochemical analysis of interleukin-1 α, β and tumor necrosis factor during experimental endotoxemia Am J Pathol 138 395 402
48. SQ Li LJ Liang JF Huang Z Li 2003 Hepatocyte apoptosis induced by hepatic ischemia-reperfusion injury in cirrhotic rats Hepatobiliary Pancreat Dis Int 2 102 105
49. X Li JF Zhang MQ Lu Y Yang C Xu H Li 2007 Alleviation of ischemia-reperfusion injury in rat liver transplantation by induction of small interference RNA targeting Fas Langenbecks Arch Surg 392 345 351 10.1007/s00423-006-0142-5
50. A Mukhopadhyay J Ni Y Zhai GL Yu 1999 Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-κB, and c-Jun NH2-terminal kinase J Biol Chem 274 15978 15981 10.1074/jbc.274.23.15978
51. S Kasibhatla T Brunner L Genestier F Echeverri A Mahboubi DR Green 1998 DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1 Mol Cell 1 543 551 10.1016/S1097-2765(00)80054-4
52. S Brown J Savill 1999 Phagocytosis triggers macrophage release of Fas ligand and induces apoptosis of bystander leukocytes J Immunol 162 480 485
53. DR Park AR Thomsen CW Frevert 2003 Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages J Immunol 170 6209 6216
54. H Tsutsui K Matsui H Okamura K Nakanishi 2000 Pathophysiological roles of interleukin-18 in inflammatory liver diseases Immunol Rev 174 192 209 10.1034/j.1600-0528.2002.017418.x
55. M Morita Y Watanabe T Akaike 1995 Protective effect of hepatocyte growth factor on interferon-γ induced cytotoxicity in mouse hepatocytes Hepatology 21 1585 1593
56. F Leithauser J Dhein G Mechtersheimer 1993 Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily in normal and neoplastic cells Lab Invest 69 415 429