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Volumn 14, Issue 4, 2003, Pages 1334-1345

Differential induction of nuclear factor-κB and activator protein-1 activity after CD40 ligation is associated with primary human hepatocyte apoptosis or intrahepatic endothelial cell proliferation

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN C FOS; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR AP 1;

EID: 0038709474     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-07-0378     Document Type: Article
Times cited : (41)

References (56)
  • 1
    • 0002470839 scopus 로고
    • Preparation of nuclear and cytoplasmic extracts from mammalian cells
    • ed. Asubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., and Struhl, K. John Wiley & Sons, New York
    • Abmayr, S.M., and Worman, J.L. (1991). Preparation of nuclear and cytoplasmic extracts from mammalian cells. In: Current Protocols in Molecular Biology, ed. Asubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., and Struhl, K. John Wiley & Sons, New York, 12.1.1-12.1.9.
    • (1991) Current Protocols in Molecular Biology , pp. 1211-1219
    • Abmayr, S.M.1    Worman, J.L.2
  • 3
    • 0029347091 scopus 로고
    • Apoptosis in the human liver during allograft rejection and end-stage liver disease
    • Afford, S.C., Hubscher, S., Strain, A.J., Adams, D.H., and Neuberger, J.M. (1995). Apoptosis in the human liver during allograft rejection and end-stage liver disease. J. Pathol. 176, 373-380.
    • (1995) J. Pathol. , vol.176 , pp. 373-380
    • Afford, S.C.1    Hubscher, S.2    Strain, A.J.3    Adams, D.H.4    Neuberger, J.M.5
  • 4
    • 0033579819 scopus 로고    scopus 로고
    • CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface FasL expression and amplifies Fas mediated hepatocyte death during allograft rejection
    • Afford, S.C., Rhandawa, S., Eliopoulos, A.G., Hubscher, S.G., Young, L.S., and Adams, D.H. (1999). CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface FasL expression and amplifies Fas mediated hepatocyte death during allograft rejection. J. Exp. Med. 189, 441-446.
    • (1999) J. Exp. Med. , vol.189 , pp. 441-446
    • Afford, S.C.1    Rhandawa, S.2    Eliopoulos, A.G.3    Hubscher, S.G.4    Young, L.S.5    Adams, D.H.6
  • 5
    • 0034657958 scopus 로고    scopus 로고
    • Roles of STAT3 defined by tissue-specific gene targeting
    • Akira, S. (2000). Roles of STAT3 defined by tissue-specific gene targeting. Oncogene 19, 2607-2611.
    • (2000) Oncogene , vol.19 , pp. 2607-2611
    • Akira, S.1
  • 6
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogenactivated protein kinase kinase in vitro and in vivo
    • Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T., and Saltiel, A.R. (1995). PD 098059 is a specific inhibitor of the activation of mitogenactivated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 7
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel, P., and Karin, M. (1991). The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta 1072, 129-157.
    • (1991) Biochim. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 8
    • 0027191429 scopus 로고
    • In situ end-labeling detects DNA strand breaks in apoptosis and other physiological and pathological states
    • Ansari, B., Coates, P.J., Greenstein, B.D., and Hall, P.A. (1993). In situ end-labeling detects DNA strand breaks in apoptosis and other physiological and pathological states. J. Pathol. 170, 1-8.
    • (1993) J. Pathol. , vol.170 , pp. 1-8
    • Ansari, B.1    Coates, P.J.2    Greenstein, B.D.3    Hall, P.A.4
  • 9
    • 0025865317 scopus 로고
    • The inducible transcription activator NF-κB: Regulation by distinct protein subunits
    • Baeuerle, P.A. (1991). The inducible transcription activator NF-κB: regulation by distinct protein subunits. Biochim. Biophys. Acta 1072, 63-80.
    • (1991) Biochim. Biophys. Acta , vol.1072 , pp. 63-80
    • Baeuerle, P.A.1
  • 10
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P.A., and Henkel, T. (1994). Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12, 141-179.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 11
    • 0028152658 scopus 로고
    • Cross-linking CD40 on B cells rapidly activates nuclear factor-κB
    • Berberich, I., Shu, G.L., and Clark, E.A. (1994). Cross-linking CD40 on B cells rapidly activates nuclear factor-κB. J. Immunol. 153, 4357-4366.
    • (1994) J. Immunol. , vol.153 , pp. 4357-4366
    • Berberich, I.1    Shu, G.L.2    Clark, E.A.3
  • 12
    • 0028932731 scopus 로고
    • The CTL's kiss of death
    • Berke, G. (1995). The CTL's kiss of death. Cell 81, 9-12.
    • (1995) Cell , vol.81 , pp. 9-12
    • Berke, G.1
  • 15
    • 0035957937 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-κB-independent mechanism
    • Cheng, N., and Chen, J. (2001). Tumor necrosis factor-α induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-κB-independent mechanism. J. Biol. Chem. 276, 13771-13777.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13771-13777
    • Cheng, N.1    Chen, J.2
  • 16
    • 0029066697 scopus 로고
    • Contenders in FasL/TNF death signaling
    • Cleveland, J.L., and Ihle, J.N. (1995). Contenders in FasL/TNF death signaling. Cell 81, 479-482.
    • (1995) Cell , vol.81 , pp. 479-482
    • Cleveland, J.L.1    Ihle, J.N.2
  • 18
    • 0033912082 scopus 로고    scopus 로고
    • CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily
    • Eliopoulos, A.G., Davies, C., Knox, P.G., Gallagher, N.J., Afford, S.C., Adams, D.H., and Young, L.S. (2000). CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily. Mol. Cell. Biol. 20, 5503-5515.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5503-5515
    • Eliopoulos, A.G.1    Davies, C.2    Knox, P.G.3    Gallagher, N.J.4    Afford, S.C.5    Adams, D.H.6    Young, L.S.7
  • 19
    • 10544246075 scopus 로고    scopus 로고
    • CD40-induced growth inhibition in epithelial cells is mimicked by Epstein-Barr Virus-encoded LMP1: Involvement of TRAF3 as a common mediator
    • Eliopoulos, A.G., et al. (1996). CD40-induced growth inhibition in epithelial cells is mimicked by Epstein-Barr Virus-encoded LMP1: involvement of TRAF3 as a common mediator. Oncogene 13, 2243-2254.
    • (1996) Oncogene , vol.13 , pp. 2243-2254
    • Eliopoulos, A.G.1
  • 20
    • 0035361599 scopus 로고    scopus 로고
    • The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine
    • Fan, M., Goodwin, M.E., Birrer, M.J., and Chambers, T.C. (2001). The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine. Cancer Res. 61, 4450-4458.
    • (2001) Cancer Res. , vol.61 , pp. 4450-4458
    • Fan, M.1    Goodwin, M.E.2    Birrer, M.J.3    Chambers, T.C.4
  • 21
    • 0033141406 scopus 로고    scopus 로고
    • NF-κB to the rescue: RELs, apoptosis and cellular transformation
    • Foo, S.Y., and Nolan, G.P. (1999). NF-κB to the rescue: RELs, apoptosis and cellular transformation. Trends Genet. 15, 229-235.
    • (1999) Trends Genet. , vol.15 , pp. 229-235
    • Foo, S.Y.1    Nolan, G.P.2
  • 23
    • 0344731406 scopus 로고    scopus 로고
    • Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the a subunit of eukaryotic translation initiation factor 2 and NF-κB
    • Gil, J., Alcami, J., and Esteban, M. (1999). Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the a subunit of eukaryotic translation initiation factor 2 and NF-κB. Mol. Cell. Biol. 19, 4653-4663.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4653-4663
    • Gil, J.1    Alcami, J.2    Esteban, M.3
  • 24
    • 0028961779 scopus 로고
    • CD40 and its ligand: Central players in B lymphocyte survival, growth, and differentiation
    • Gordon, J. (1995). CD40 and its ligand: central players in B lymphocyte survival, growth, and differentiation. Blood Rev. 9, 53-56.
    • (1995) Blood Rev. , vol.9 , pp. 53-56
    • Gordon, J.1
  • 25
    • 0030917141 scopus 로고    scopus 로고
    • Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells
    • Hanissian, S.H., and Geha, R.S. (1997). Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells. Immunity 6, 379-387.
    • (1997) Immunity , vol.6 , pp. 379-387
    • Hanissian, S.H.1    Geha, R.S.2
  • 26
    • 0030663215 scopus 로고    scopus 로고
    • Enhanced apoptosis relates to bile duct loss in primary biliary cirrhosis
    • Harada, K., Ozaki, S., Gershwin, M.E., and Nakanuma, Y. (1997). Enhanced apoptosis relates to bile duct loss in primary biliary cirrhosis. Hepatology 27, 1399-1405.
    • (1997) Hepatology , vol.27 , pp. 1399-1405
    • Harada, K.1    Ozaki, S.2    Gershwin, M.E.3    Nakanuma, Y.4
  • 27
    • 0030067795 scopus 로고    scopus 로고
    • A novel function of CD40: Induction of cell death in transformed cells
    • Hess, S., and Engelmann, H. (1996). A novel function of CD40: induction of cell death in transformed cells. J. Exp. Med. 183, 159-167.
    • (1996) J. Exp. Med. , vol.183 , pp. 159-167
    • Hess, S.1    Engelmann, H.2
  • 29
    • 0032549017 scopus 로고    scopus 로고
    • Transcriptional regulation of the human FasL promoter-enhancer region
    • Holtz-Heppelmann, C.J., Algeciras, A., Badley, A.D., and Paya, C.V. (1998). Transcriptional regulation of the human FasL promoter-enhancer region. J. Biol. Chem. 273, 4416-4423.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4416-4423
    • Holtz-Heppelmann, C.J.1    Algeciras, A.2    Badley, A.D.3    Paya, C.V.4
  • 30
    • 0033966202 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle cell proliferation by nuclear factor-κB and its inhibitor, I-κB
    • Hoshi, S., Goto, M., Koyama, N., Nomoto, K., and Tanaka, H. (2000). Regulation of vascular smooth muscle cell proliferation by nuclear factor-κB and its inhibitor, I-κB. J. Biol. Chem. 275, 883-889.
    • (2000) J. Biol. Chem. , vol.275 , pp. 883-889
    • Hoshi, S.1    Goto, M.2    Koyama, N.3    Nomoto, K.4    Tanaka, H.5
  • 32
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin, M. (1995). The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 270, 16483-16486.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 33
    • 0033534465 scopus 로고    scopus 로고
    • Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor κB
    • Kasibhatla, S., Genestier, L., and Green, D.R. (1999). Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor κB. J. Biol. Chem. 274, 987-992.
    • (1999) J. Biol. Chem. , vol.274 , pp. 987-992
    • Kasibhatla, S.1    Genestier, L.2    Green, D.R.3
  • 34
    • 0031002790 scopus 로고    scopus 로고
    • Essential roles of the Fas ligand in the development of hepatitis
    • Kondo, T., Suda, T., Fukuyama, H., Adachi, M., and Nagata, S. (1997). Essential roles of the Fas ligand in the development of hepatitis. Nat. Med. 3, 409-413.
    • (1997) Nat. Med. , vol.3 , pp. 409-413
    • Kondo, T.1    Suda, T.2    Fukuyama, H.3    Adachi, M.4    Nagata, S.5
  • 35
    • 0033621839 scopus 로고    scopus 로고
    • NFκB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis
    • Kuhnel, F., Zender, L., Paul, Y., Tietze, M.K., Trautwein, C., Manns, M., and Kubicka, S. (2000). NFκB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis. J. Biol. Chem. 275, 6421-6427.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6421-6427
    • Kuhnel, F.1    Zender, L.2    Paul, Y.3    Tietze, M.K.4    Trautwein, C.5    Manns, M.6    Kubicka, S.7
  • 36
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis, J.M., and Avruch, J. (2001). Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81, 807-869.
    • (2001) Physiol. Rev. , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 37
    • 0037100288 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 mediates adhesion and transendothelial migration of lymphocytes on human hepatic endothelial cells
    • Lalor, P.F., Edwards, S., McNab, G., Salmi, M., Jalkanen, S., and Adams, D.H. (2002). Vascular adhesion protein-1 mediates adhesion and transendothelial migration of lymphocytes on human hepatic endothelial cells. J. Immunol. 169, 983-992.
    • (2002) J. Immunol. , vol.169 , pp. 983-992
    • Lalor, P.F.1    Edwards, S.2    McNab, G.3    Salmi, M.4    Jalkanen, S.5    Adams, D.H.6
  • 38
    • 0032937879 scopus 로고    scopus 로고
    • Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death
    • Le-Niculescu, H., Bonfoco, E., Kasuya, Y., Claret, F.X., Green, D.R., and Karin, M. (1999). Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol. Cell. Biol. 19, 751-763.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 751-763
    • Le-Niculescu, H.1    Bonfoco, E.2    Kasuya, Y.3    Claret, F.X.4    Green, D.R.5    Karin, M.6
  • 39
    • 0028899112 scopus 로고
    • Role of Rel-related factors in control of c-myc gene transcription in receptor-mediated apoptosis of the murine B cell WEHI 231 line
    • Lee, H., Arsura, M., Wu, M., Duyao, M., Buckler, A.J., and Sonenshein, G.E. (1995). Role of Rel-related factors in control of c-myc gene transcription in receptor-mediated apoptosis of the murine B cell WEHI 231 line. J. Exp. Med. 181, 1169-1177.
    • (1995) J. Exp. Med. , vol.181 , pp. 1169-1177
    • Lee, H.1    Arsura, M.2    Wu, M.3    Duyao, M.4    Buckler, A.J.5    Sonenshein, G.E.6
  • 40
    • 0035086794 scopus 로고    scopus 로고
    • Nuclear factor-κB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells
    • Lim, J.W., Kim, H., and Kim, K.H. (2001). Nuclear factor-κB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells. Lab. Invest. 81, 349-360.
    • (2001) Lab. Invest. , vol.81 , pp. 349-360
    • Lim, J.W.1    Kim, H.2    Kim, K.H.3
  • 41
    • 10344245047 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor signal transduction in endothelial cells by dimethylaminopurine
    • Marino, M.W., et al. (1996). Inhibition of tumor necrosis factor signal transduction in endothelial cells by dimethylaminopurine. J. Biol. Chem. 271, 28624-28629.
    • (1996) J. Biol. Chem. , vol.271 , pp. 28624-28629
    • Marino, M.W.1
  • 42
    • 0029810902 scopus 로고    scopus 로고
    • Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB
    • Natarajan, K., Singh, S., Burke, T.R.J., Grunberger, D., and Aggarwal, B.B. (1996). Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proc. Natl. Acad. Sci. USA 93, 9090-9095.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9090-9095
    • Natarajan, K.1    Singh, S.2    Burke, T.R.J.3    Grunberger, D.4    Aggarwal, B.B.5
  • 44
    • 0030611782 scopus 로고    scopus 로고
    • Regulation of IκBβ in WEHI 231 mature B cells
    • Phillips, R.J., and Ghosh, S. (1997). Regulation of IκBβ in WEHI 231 mature B cells. Mol. Cell. Biol. 17, 4390-4396.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4390-4396
    • Phillips, R.J.1    Ghosh, S.2
  • 45
    • 0035336310 scopus 로고    scopus 로고
    • CD40 activates NF-κB and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells
    • Schwabe, R.F., Schnabl, B., Kweon, Y.O., and Brenner, D.A. (2001). CD40 activates NF-κB and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. J. Immunol. 166, 6812-6819.
    • (2001) J. Immunol. , vol.166 , pp. 6812-6819
    • Schwabe, R.F.1    Schnabl, B.2    Kweon, Y.O.3    Brenner, D.A.4
  • 46
    • 0028353492 scopus 로고
    • The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
    • Smith, C.A., Farrah, T., and Goodwin, R.G. (1994). The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 76, 959-962.
    • (1994) Cell , vol.76 , pp. 959-962
    • Smith, C.A.1    Farrah, T.2    Goodwin, R.G.3
  • 47
    • 0025855880 scopus 로고
    • Native and recombinant human hepatocyte growth factor are highly potent promoters of DNA synthesis in both human and rat hepatocytes
    • Strain, A.J., Ismail, T., Tsubouchi, H., Arakaki, N., Hishida, T., Kitamura, N., Daikuhara, Y., and McMaster, P. (1991). Native and recombinant human hepatocyte growth factor are highly potent promoters of DNA synthesis in both human and rat hepatocytes. J. Clin. Invest. 87, 1853-1857.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1853-1857
    • Strain, A.J.1    Ismail, T.2    Tsubouchi, H.3    Arakaki, N.4    Hishida, T.5    Kitamura, N.6    Daikuhara, Y.7    McMaster, P.8
  • 49
    • 0035852646 scopus 로고    scopus 로고
    • Regulation of CD40 function by its isoforms generated through alternative splicing
    • Tone, M., Tone, Y., Fairchild, P.J., Wykes, M., and Waldmann, H. (2001). Regulation of CD40 function by its isoforms generated through alternative splicing. Proc. Natl. Acad. Sci. USA 98, 1751-1756.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1751-1756
    • Tone, M.1    Tone, Y.2    Fairchild, P.J.3    Wykes, M.4    Waldmann, H.5
  • 50
    • 0033574051 scopus 로고    scopus 로고
    • Two differently regulated nuclear factor κB activation pathways triggered by the cytoplasmic tail of CD40
    • Tsukamoto, N., Kobayashi, N., Azuma, S., Yamamoto, T., and Inoue, J. (1999). Two differently regulated nuclear factor κB activation pathways triggered by the cytoplasmic tail of CD40. Proc. Natl. Acad. Sci. USA 96, 1234-1239.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1234-1239
    • Tsukamoto, N.1    Kobayashi, N.2    Azuma, S.3    Yamamoto, T.4    Inoue, J.5
  • 51
    • 0034321935 scopus 로고    scopus 로고
    • Immune regulation by CD40-CD40-1 interactions-2; Y2K update
    • Van Kooten, C. (2000). Immune regulation by CD40-CD40-1 interactions-2; Y2K update. Front. Biosci. 5, D880-D693.
    • (2000) Front. Biosci. , vol.5
    • Van Kooten, C.1
  • 52
    • 0030744132 scopus 로고    scopus 로고
    • Functions of CD40 on B cells, dendritic cells and other cells
    • Van Kooten, C., and Bancherau, J. (1997). Functions of CD40 on B cells, dendritic cells and other cells. Curr. Opin. Immunol. 9, 330-337.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 330-337
    • Van Kooten, C.1    Bancherau, J.2
  • 53
    • 0033559616 scopus 로고    scopus 로고
    • Stimulation of CD40 on immunogenic human malignant melanomas augments their cytotoxic T lymphocyte-mediated lysis and induces apoptosis
    • von Leoprechting, A., Van der Bruggen, P., Pahl, H.L., Aruffo, A., and Simon, J.C. (1999). Stimulation of CD40 on immunogenic human malignant melanomas augments their cytotoxic T lymphocyte-mediated lysis and induces apoptosis. Cancer Res. 59, 1287-1294.
    • (1999) Cancer Res. , vol.59 , pp. 1287-1294
    • Von Leoprechting, A.1    Van der Bruggen, P.2    Pahl, H.L.3    Aruffo, A.4    Simon, J.C.5
  • 54
    • 0028167599 scopus 로고
    • NF-κB activation of p53. A potential mechanism for suppressing cell growth in response to stress
    • Wu, H., and Lozano, G. (1994). NF-κB activation of p53. A potential mechanism for suppressing cell growth in response to stress. J. Biol. Chem. 269, 20067-20074.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20067-20074
    • Wu, H.1    Lozano, G.2
  • 55
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia, Z., Dickens, M., Raingeaud, J., Davis, R.J., and Greenberg, M.E. (1995). Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5


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