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Volumn 45, Issue 2, 2012, Pages 185-195

Epigenetic Mechanisms of Groucho/Grg/TLE Mediated Transcriptional Repression

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN PTIP; COREPRESSOR PROTEIN; COREPRESSOR PROTEIN GRG4; DNA BINDING PROTEIN; GROUCHO PROTEIN; GROUCHO RELATED PROTEIN; HISTONE H3; POLYCOMB GROUP PROTEIN; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE PRMT5; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR PAX2; TRANSDUCIN LIKE ENHANCER OF SPLIT PROTEIN; UNCLASSIFIED DRUG;

EID: 84856291642     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2011.11.007     Document Type: Article
Times cited : (57)

References (59)
  • 4
    • 0034697973 scopus 로고    scopus 로고
    • BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer
    • Bochar D.A., Wang L., Beniya H., Kinev A., Xue Y., Lane W.S., Wang W., Kashanchi F., Shiekhattar R. BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell 2000, 102:257-265.
    • (2000) Cell , vol.102 , pp. 257-265
    • Bochar, D.A.1    Wang, L.2    Beniya, H.3    Kinev, A.4    Xue, Y.5    Lane, W.S.6    Wang, W.7    Kashanchi, F.8    Shiekhattar, R.9
  • 6
    • 0035215311 scopus 로고    scopus 로고
    • Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene
    • Brophy P.D., Ostrom L., Lang K.M., Dressler G.R. Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene. Development 2001, 128:4747-4756.
    • (2001) Development , vol.128 , pp. 4747-4756
    • Brophy, P.D.1    Ostrom, L.2    Lang, K.M.3    Dressler, G.R.4
  • 7
    • 0030690322 scopus 로고    scopus 로고
    • PAX2 is expressed in multiple spinal cord interneurons, including a population of EN1+ interneurons that require PAX6 for their development
    • Burrill J.D., Moran L., Goulding M.D., Saueressig H. PAX2 is expressed in multiple spinal cord interneurons, including a population of EN1+ interneurons that require PAX6 for their development. Development 1997, 124:4493-4503.
    • (1997) Development , vol.124 , pp. 4493-4503
    • Burrill, J.D.1    Moran, L.2    Goulding, M.D.3    Saueressig, H.4
  • 8
    • 0037059748 scopus 로고    scopus 로고
    • Phosphorylation of Pax2 by the c-Jun N-terminal kinase and enhanced Pax2-dependent transcription activation
    • Cai Y., Lechner M.S., Nihalani D., Prindle M.J., Holzman L.B., Dressler G.R. Phosphorylation of Pax2 by the c-Jun N-terminal kinase and enhanced Pax2-dependent transcription activation. J.Biol. Chem. 2002, 277:1217-1222.
    • (2002) J.Biol. Chem. , vol.277 , pp. 1217-1222
    • Cai, Y.1    Lechner, M.S.2    Nihalani, D.3    Prindle, M.J.4    Holzman, L.B.5    Dressler, G.R.6
  • 9
    • 0142137133 scopus 로고    scopus 로고
    • Groucho suppresses Pax2 transactivation by inhibition of JNK-mediated phosphorylation
    • Cai Y., Brophy P.D., Levitan I., Stifani S., Dressler G.R. Groucho suppresses Pax2 transactivation by inhibition of JNK-mediated phosphorylation. EMBO J. 2003, 22:5522-5529.
    • (2003) EMBO J. , vol.22 , pp. 5522-5529
    • Cai, Y.1    Brophy, P.D.2    Levitan, I.3    Stifani, S.4    Dressler, G.R.5
  • 10
    • 70450225375 scopus 로고    scopus 로고
    • The Kruppel-like zinc finger protein ZNF224 recruits the arginine methyltransferase PRMT5 on the transcriptional repressor complex of the aldolase A gene
    • Cesaro E., De Cegli R., Medugno L., Florio F., Grosso M., Lupo A., Izzo P., Costanzo P. The Kruppel-like zinc finger protein ZNF224 recruits the arginine methyltransferase PRMT5 on the transcriptional repressor complex of the aldolase A gene. J.Biol. Chem. 2009, 284:32321-32330.
    • (2009) J.Biol. Chem. , vol.284 , pp. 32321-32330
    • Cesaro, E.1    De Cegli, R.2    Medugno, L.3    Florio, F.4    Grosso, M.5    Lupo, A.6    Izzo, P.7    Costanzo, P.8
  • 11
    • 0034673929 scopus 로고    scopus 로고
    • Groucho/TLE family proteins and transcriptional repression
    • Chen G., Courey A.J. Groucho/TLE family proteins and transcriptional repression. Gene 2000, 249:1-16.
    • (2000) Gene , vol.249 , pp. 1-16
    • Chen, G.1    Courey, A.J.2
  • 13
    • 56049107271 scopus 로고    scopus 로고
    • Context-dependent regulation of Groucho/TLE-mediated repression
    • Cinnamon E., Paroush Z. Context-dependent regulation of Groucho/TLE-mediated repression. Curr. Opin. Genet. Dev. 2008, 18:435-440.
    • (2008) Curr. Opin. Genet. Dev. , vol.18 , pp. 435-440
    • Cinnamon, E.1    Paroush, Z.2
  • 15
    • 0343183096 scopus 로고    scopus 로고
    • Transcriptional repression by Pax5 (BSAP) through interaction with co-repressors of the Groucho family
    • Eberhard D., Jiménez G., Heavey B., Busslinger M. Transcriptional repression by Pax5 (BSAP) through interaction with co-repressors of the Groucho family. EMBO J. 2000, 19:2292-2303.
    • (2000) EMBO J. , vol.19 , pp. 2292-2303
    • Eberhard, D.1    Jiménez, G.2    Heavey, B.3    Busslinger, M.4
  • 17
    • 33646838386 scopus 로고    scopus 로고
    • Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively invitro
    • Furuno K., Masatsugu T., Sonoda M., Sasazuki T., Yamamoto K. Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively invitro. Biochem. Biophys. Res. Commun. 2006, 345:1051-1058.
    • (2006) Biochem. Biophys. Res. Commun. , vol.345 , pp. 1051-1058
    • Furuno, K.1    Masatsugu, T.2    Sonoda, M.3    Sasazuki, T.4    Yamamoto, K.5
  • 18
    • 0030044345 scopus 로고    scopus 로고
    • Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila
    • Heitzler P., Bourouis M., Ruel L., Carteret C., Simpson P. Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 1996, 122:161-171.
    • (1996) Development , vol.122 , pp. 161-171
    • Heitzler, P.1    Bourouis, M.2    Ruel, L.3    Carteret, C.4    Simpson, P.5
  • 19
    • 77952678006 scopus 로고    scopus 로고
    • Epigenetic control of neural precursor cell fate during development
    • Hirabayashi Y., Gotoh Y. Epigenetic control of neural precursor cell fate during development. Nat. Rev. Neurosci. 2010, 11:377-388.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 377-388
    • Hirabayashi, Y.1    Gotoh, Y.2
  • 20
    • 33645326509 scopus 로고    scopus 로고
    • Comparison of Affymetrix GeneChip expression measures
    • Irizarry R.A., Wu Z., Jaffee H.A. Comparison of Affymetrix GeneChip expression measures. Bioinformatics 2006, 22:789-794.
    • (2006) Bioinformatics , vol.22 , pp. 789-794
    • Irizarry, R.A.1    Wu, Z.2    Jaffee, H.A.3
  • 21
    • 77951454833 scopus 로고    scopus 로고
    • The Groucho/TLE/Grg family of transcriptional co-repressors
    • Jennings B.H., Ish-Horowicz D. The Groucho/TLE/Grg family of transcriptional co-repressors. Genome Biol. 2008, 9:205.
    • (2008) Genome Biol. , vol.9 , pp. 205
    • Jennings, B.H.1    Ish-Horowicz, D.2
  • 22
    • 33744514127 scopus 로고    scopus 로고
    • Molecular recognition of transcriptional repressor motifs by the WD domain of the Groucho/TLE co-repressor
    • Jennings B.H., Pickles L.M., Wainwright S.M., Roe S.M., Perl L.H., Ish-Horowicz D. Molecular recognition of transcriptional repressor motifs by the WD domain of the Groucho/TLE co-repressor. Mol. Cell 2006, 22:645-655.
    • (2006) Mol. Cell , vol.22 , pp. 645-655
    • Jennings, B.H.1    Pickles, L.M.2    Wainwright, S.M.3    Roe, S.M.4    Perl, L.H.5    Ish-Horowicz, D.6
  • 23
    • 68049125869 scopus 로고    scopus 로고
    • The role of PTIP in maintaining embryonic stem cell pluripotency
    • Kim D., Patel S.R., Xiao H., Dressler G.R. The role of PTIP in maintaining embryonic stem cell pluripotency. Stem Cells 2009, 27:1516-1523.
    • (2009) Stem Cells , vol.27 , pp. 1516-1523
    • Kim, D.1    Patel, S.R.2    Xiao, H.3    Dressler, G.R.4
  • 24
    • 0030248449 scopus 로고    scopus 로고
    • Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development
    • Koop K.E., MacDonald L.M., Lobe C.G. Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech. Dev. 1996, 59:73-87.
    • (1996) Mech. Dev. , vol.59 , pp. 73-87
    • Koop, K.E.1    MacDonald, L.M.2    Lobe, C.G.3
  • 25
    • 43049084803 scopus 로고    scopus 로고
    • The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5
    • Lacroix M., El Messaoudi S., Rodier G., Le Cam A., Sardet C., Fabbrizio E. The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5. EMBO Rep. 2008, 9:452-458.
    • (2008) EMBO Rep. , vol.9 , pp. 452-458
    • Lacroix, M.1    El Messaoudi, S.2    Rodier, G.3    Le Cam, A.4    Sardet, C.5    Fabbrizio, E.6
  • 26
    • 0026651978 scopus 로고
    • Ethidium bromide provides a simple tool for identifying gaenuine DNA-independent protein associations
    • Lai J.S., Herr W. Ethidium bromide provides a simple tool for identifying gaenuine DNA-independent protein associations. Proc. Natl. Acad. Sci. USA 1992, 89:6958-6962.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6958-6962
    • Lai, J.S.1    Herr, W.2
  • 27
    • 78449235454 scopus 로고    scopus 로고
    • Altering a histone H3K4 methylation pathway in glomerular podocytes promotes a chronic disease phenotype
    • Lefevre G.M., Patel S.R., Kim D., Tessarollo L., Dressler G.R. Altering a histone H3K4 methylation pathway in glomerular podocytes promotes a chronic disease phenotype. PLoS Genet. 2010, 6:e1001142.
    • (2010) PLoS Genet. , vol.6
    • Lefevre, G.M.1    Patel, S.R.2    Kim, D.3    Tessarollo, L.4    Dressler, G.R.5
  • 28
    • 16544393313 scopus 로고    scopus 로고
    • Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes
    • Linderson Y., Eberhard D., Malin S., Johansson A., Busslinger M., Pettersson S. Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes. EMBO Rep. 2004, 5:291-296.
    • (2004) EMBO Rep. , vol.5 , pp. 291-296
    • Linderson, Y.1    Eberhard, D.2    Malin, S.3    Johansson, A.4    Busslinger, M.5    Pettersson, S.6
  • 29
    • 48049110892 scopus 로고    scopus 로고
    • Epigenetic regulation of stem cell fate
    • Lunyak V.V., Rosenfeld M.G. Epigenetic regulation of stem cell fate. Hum. Mol. Genet. 2008, 17(R1):R28-R36.
    • (2008) Hum. Mol. Genet. , vol.17 , Issue.R1
    • Lunyak, V.V.1    Rosenfeld, M.G.2
  • 31
    • 0035937415 scopus 로고    scopus 로고
    • Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube
    • Muhr J., Andersson E., Persson M., Jessell T.M., Ericson J. Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube. Cell 2001, 104:861-873.
    • (2001) Cell , vol.104 , pp. 861-873
    • Muhr, J.1    Andersson, E.2    Persson, M.3    Jessell, T.M.4    Ericson, J.5
  • 32
    • 1642305951 scopus 로고    scopus 로고
    • Polarity and laminar formation of the optic tectum in relation to retinal projection
    • Nakamura H., Sugiyama S. Polarity and laminar formation of the optic tectum in relation to retinal projection. J.Neurobiol. 2004, 59:48-56.
    • (2004) J.Neurobiol. , vol.59 , pp. 48-56
    • Nakamura, H.1    Sugiyama, S.2
  • 33
    • 0041668113 scopus 로고    scopus 로고
    • Methods and tips for the purification of human histone methyltransferases
    • Nishioka K., Reinberg D. Methods and tips for the purification of human histone methyltransferases. Methods 2003, 31:49-58.
    • (2003) Methods , vol.31 , pp. 49-58
    • Nishioka, K.1    Reinberg, D.2
  • 34
    • 33745549658 scopus 로고    scopus 로고
    • Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations
    • O'Neill L.P., VerMilyea M.D., Turner B.M. Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations. Nat. Genet. 2006, 38:835-841.
    • (2006) Nat. Genet. , vol.38 , pp. 835-841
    • O'Neill, L.P.1    VerMilyea, M.D.2    Turner, B.M.3
  • 35
    • 70449099301 scopus 로고    scopus 로고
    • Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
    • Otani J., Nankumo T., Arita K., Inamoto S., Ariyoshi M., Shirakawa M. Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain. EMBO Rep. 2009, 10:1235-1241.
    • (2009) EMBO Rep. , vol.10 , pp. 1235-1241
    • Otani, J.1    Nankumo, T.2    Arita, K.3    Inamoto, S.4    Ariyoshi, M.5    Shirakawa, M.6
  • 36
    • 6344222803 scopus 로고    scopus 로고
    • Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes
    • Pal S., Vishwanath S.N., Erdjument-Bromage H., Tempst P., Sif S. Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. Mol. Cell. Biol. 2004, 24:9630-9645.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9630-9645
    • Pal, S.1    Vishwanath, S.N.2    Erdjument-Bromage, H.3    Tempst, P.4    Sif, S.5
  • 37
    • 0028170530 scopus 로고
    • Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins
    • Paroush Z., Finley R.L., Kidd T., Wainwright S.M., Ingham P.W., Brent R., Ish-Horowicz D. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell 1994, 79:805-815.
    • (1994) Cell , vol.79 , pp. 805-815
    • Paroush, Z.1    Finley, R.L.2    Kidd, T.3    Wainwright, S.M.4    Ingham, P.W.5    Brent, R.6    Ish-Horowicz, D.7
  • 38
    • 1542357303 scopus 로고    scopus 로고
    • Expression of Pax2 in the intermediate mesoderm is regulated by YY1
    • Patel S.R., Dressler G.R. Expression of Pax2 in the intermediate mesoderm is regulated by YY1. Dev. Biol. 2004, 267:505-516.
    • (2004) Dev. Biol. , vol.267 , pp. 505-516
    • Patel, S.R.1    Dressler, G.R.2
  • 39
    • 34848880490 scopus 로고    scopus 로고
    • The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex
    • Patel S.R., Kim D., Levitan I., Dressler G.R. The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex. Dev. Cell 2007, 13:580-592.
    • (2007) Dev. Cell , vol.13 , pp. 580-592
    • Patel, S.R.1    Kim, D.2    Levitan, I.3    Dressler, G.R.4
  • 40
    • 33846983276 scopus 로고    scopus 로고
    • Polycomb/Trithorax response elements and epigenetic memory of cell identity
    • Ringrose L., Paro R. Polycomb/Trithorax response elements and epigenetic memory of cell identity. Development 2007, 134:223-232.
    • (2007) Development , vol.134 , pp. 223-232
    • Ringrose, L.1    Paro, R.2
  • 41
    • 30144439616 scopus 로고    scopus 로고
    • A PANorama of PAX genes in cancer and development
    • Robson E.J., He S.J., Eccles M.R. A PANorama of PAX genes in cancer and development. Nat. Rev. Cancer 2006, 6:52-62.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 52-62
    • Robson, E.J.1    He, S.J.2    Eccles, M.R.3
  • 42
    • 0026738021 scopus 로고
    • The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells
    • Schrons H., Knust E., Campos-Ortega J.A. The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells. Genetics 1992, 132:481-503.
    • (1992) Genetics , vol.132 , pp. 481-503
    • Schrons, H.1    Knust, E.2    Campos-Ortega, J.A.3
  • 44
    • 79953769946 scopus 로고    scopus 로고
    • Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locus
    • Schwab K.R., Patel S.R., Dressler G.R. Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locus. Mol. Cell. Biol. 2011, 31:1503-1511.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 1503-1511
    • Schwab, K.R.1    Patel, S.R.2    Dressler, G.R.3
  • 45
  • 46
    • 35349013604 scopus 로고    scopus 로고
    • Repression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin invitro and impairs activator binding invivo
    • Sekiya T., Zaret K.S. Repression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin invitro and impairs activator binding invivo. Mol. Cell 2007, 28:291-303.
    • (2007) Mol. Cell , vol.28 , pp. 291-303
    • Sekiya, T.1    Zaret, K.S.2
  • 47
    • 44649139771 scopus 로고    scopus 로고
    • Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation
    • Shilatifard A. Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation. Curr. Opin. Cell Biol. 2008, 20:341-348.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 341-348
    • Shilatifard, A.1
  • 48
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth G.K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004, 3. Article3.
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 50
    • 0037324147 scopus 로고    scopus 로고
    • The role of Grg4 in tectal laminar formation
    • Sugiyama S., Nakamura H. The role of Grg4 in tectal laminar formation. Development 2003, 130:451-462.
    • (2003) Development , vol.130 , pp. 451-462
    • Sugiyama, S.1    Nakamura, H.2
  • 51
    • 0034194192 scopus 로고    scopus 로고
    • Antagonizing activity of chick Grg4 against tectum-organizing activity
    • Sugiyama S., Funahashi J., Nakamura H. Antagonizing activity of chick Grg4 against tectum-organizing activity. Dev. Biol. 2000, 221:168-180.
    • (2000) Dev. Biol. , vol.221 , pp. 168-180
    • Sugiyama, S.1    Funahashi, J.2    Nakamura, H.3
  • 52
    • 80052252127 scopus 로고    scopus 로고
    • Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes
    • Tae S., Karkhanis V., Velasco K., Yaneva M., Erdjument-Bromage H., Tempst P., Sif S. Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes. Nucleic Acids Res. 2011, 39:5424-5438.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5424-5438
    • Tae, S.1    Karkhanis, V.2    Velasco, K.3    Yaneva, M.4    Erdjument-Bromage, H.5    Tempst, P.6    Sif, S.7
  • 53
    • 0029590072 scopus 로고
    • Pax-2 controls multiple steps of urogenital development
    • Torres M., Gómez-Pardo E., Dressler G.R., Gruss P. Pax-2 controls multiple steps of urogenital development. Development 1995, 121:4057-4065.
    • (1995) Development , vol.121 , pp. 4057-4065
    • Torres, M.1    Gómez-Pardo, E.2    Dressler, G.R.3    Gruss, P.4
  • 54
    • 0029953417 scopus 로고    scopus 로고
    • Pax2 contributes to inner ear patterning and optic nerve trajectory
    • Torres M., Gómez-Pardo E., Gruss P. Pax2 contributes to inner ear patterning and optic nerve trajectory. Development 1996, 122:3381-3391.
    • (1996) Development , vol.122 , pp. 3381-3391
    • Torres, M.1    Gómez-Pardo, E.2    Gruss, P.3
  • 55
    • 53549103598 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells
    • Wang L., Pal S., Sif S. Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells. Mol. Cell. Biol. 2008, 28:6262-6277.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 6262-6277
    • Wang, L.1    Pal, S.2    Sif, S.3
  • 56
    • 77954766475 scopus 로고    scopus 로고
    • Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
    • Xu X., Hoang S., Mayo M.W., Bekiranov S. Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression. BMC Bioinformatics 2010, 11:396.
    • (2010) BMC Bioinformatics , vol.11 , pp. 396
    • Xu, X.1    Hoang, S.2    Mayo, M.W.3    Bekiranov, S.4
  • 58
    • 0036211850 scopus 로고    scopus 로고
    • The N-CoR-HDAC3 nuclear receptor co-repressor complex inhibits the JNK pathway through the integral subunit GPS2
    • Zhang J., Kalkum M., Chait B.T., Roeder R.G. The N-CoR-HDAC3 nuclear receptor co-repressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol. Cell 2002, 9:611-623.
    • (2002) Mol. Cell , vol.9 , pp. 611-623
    • Zhang, J.1    Kalkum, M.2    Chait, B.T.3    Roeder, R.G.4


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