-
1
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier, R.J., Podolsky, D.K. (2007) Unravelling the pathogenesis of inflammatory bowel disease, Nature 448, 427-34.
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
2
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke, A., McGovern, D.P., Barrett, J. C. et al. (2010) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci, Nat Genet 42, 1118-25.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
-
3
-
-
33847381116
-
The fundamental basis of inflammatory bowel disease
-
Strober, W., Fuss, I., Mannon, P. (2007) The fundamental basis of inflammatory bowel disease, J Clin Invest 117, 514-21.
-
(2007)
J Clin Invest
, vol.117
, pp. 514-521
-
-
Strober, W.1
Fuss, I.2
Mannon, P.3
-
4
-
-
0028519015
-
Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
-
Powrie, F., Leach, M.W., Mauze, S. et al. (1994) Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells, Immunity 1, 553-62.
-
(1994)
Immunity
, vol.1
, pp. 553-562
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
-
5
-
-
34347262689
-
Chemically induced mouse models of intestinal inflammation
-
Wirtz, S., Neufert, C., Weigmann, B. et al. (2007) Chemically induced mouse models of intestinal inflammation, Nat Protocols 2, 541-546.
-
(2007)
Nat Protocols
, vol.2
, pp. 541-546
-
-
Wirtz, S.1
Neufert, C.2
Weigmann, B.3
-
6
-
-
0036218221
-
The immunology of mucosal models of inflammation
-
Strober, W., Fuss, I.J., Blumberg, R.S. (2002) The immunology of mucosal models of inflammation, Annu Rev Immunol 20, 495-549.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 495-549
-
-
Strober, W.1
Fuss, I.J.2
Blumberg, R.S.3
-
7
-
-
0032828954
-
The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis
-
Qiu, B.S., Vallance, B.A., Blennerhassett, P.A. et al. (1999) The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis, Nat Med 5, 1178-82.
-
(1999)
Nat Med
, vol.5
, pp. 1178-1182
-
-
Qiu, B.S.1
Vallance, B.A.2
Blennerhassett, P.A.3
-
8
-
-
0011469747
-
Induction of TNBS colitis in mice
-
Unit 15. 19 doi: 10.1002/0471142735.im1519s49
-
Scheiffele, F., Fuss, I.J. (2002) Induction of TNBS colitis in mice, Curr Protoc Immunol Unit 15.19 doi: 10.1002/0471142735.im1519s49.
-
(2002)
Curr Protoc Immunol
-
-
Scheiffele, F.1
Fuss, I.J.2
-
9
-
-
0036850908
-
Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells
-
Heller, F., Fuss, I. J. Nieuwenhuis, E.E. et al. (2002) Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells, Immunity 17, 629-38.
-
(2002)
Immunity
, vol.17
, pp. 629-638
-
-
Heller, F.1
Fuss, I.J.2
Nieuwenhuis, E.E.3
-
10
-
-
0034327176
-
Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression
-
Gorelik, L., Fields, P.E., Flavell, R.A. (2000) Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression, J Immunol 165, 4773-7.
-
(2000)
J Immunol
, vol.165
, pp. 4773-4777
-
-
Gorelik, L.1
Fields, P.E.2
Flavell, R.A.3
-
11
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
-
Shull, M.M., Ormsby, I., Kier, A.B. et al. (1992) Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease, Nature 359, 693-9.
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
Ormsby, I.2
Kier, A.B.3
-
12
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn, R., Lohler, J., Rennick, D. et al. (1993) Interleukin-10-deficient mice develop chronic enterocolitis, Cell 75, 263-74.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
-
13
-
-
0029083269
-
Interleukin-10 gene knock-out mice: A model of chronic inflammation
-
Rennick, D., Davidson, N., Berg, D. (1995) Interleukin-10 gene knock-out mice: a model of chronic inflammation, Clin Immunol Immunopathol 76, S174-8.
-
(1995)
Clin Immunol Immunopathol
, vol.76
-
-
Rennick, D.1
Davidson, N.2
Berg, D.3
-
14
-
-
0033034365
-
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
-
Takeda, K., Clausen, B. E., Kaisho, T. et al. (1999) Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils, Immunity 10, 39-49.
-
(1999)
Immunity
, vol.10
, pp. 39-49
-
-
Takeda, K.1
Clausen, B.E.2
Kaisho, T.3
-
15
-
-
0032550312
-
T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells
-
Simpson, S.J., Shah, S., Comiskey, M. et al. (1998) T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells, J Exp Med 187, 1225-34.
-
(1998)
J Exp Med
, vol.187
, pp. 1225-1234
-
-
Simpson, S.J.1
Shah, S.2
Comiskey, M.3
-
16
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi, K.S., Chamaillard, M., Ogura, Y. et al. (2005) Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract, Science 307, 731-4.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
-
17
-
-
0031811879
-
Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain
-
Matsumoto, S., Okabe, Y., Setoyama, H. et al. (1998) Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain, Gut 43, 71-8.
-
(1998)
Gut
, vol.43
, pp. 71-78
-
-
Matsumoto, S.1
Okabe, Y.2
Setoyama, H.3
-
18
-
-
0032118427
-
Wiskott-Aldrich syndrome proteindeficient mice reveal a role for WASP in T but not B cell activation
-
Snapper, S.B., Rosen, F.S., Mizoguchi, E. et al. (1998) Wiskott-Aldrich syndrome proteindeficient mice reveal a role for WASP in T but not B cell activation, Immunity 9, 81-91.
-
(1998)
Immunity
, vol.9
, pp. 81-91
-
-
Snapper, S.B.1
Rosen, F.S.2
Mizoguchi, E.3
-
19
-
-
0034730713
-
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
-
Lee, E.G., Boone, D.L., Chai, S. et al. (2000) Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice, Science 289, 2350-4.
-
(2000)
Science
, vol.289
, pp. 2350-2354
-
-
Lee, E.G.1
Boone, D.L.2
Chai, S.3
-
20
-
-
0032901919
-
The critical role of interleukin 4 but not interferon gamma in the pathogenesis of colitis in T-cell receptor alpha mutant mice
-
Mizoguchi, A., Mizoguchi, E., Bhan, A.K. (1999) The critical role of interleukin 4 but not interferon gamma in the pathogenesis of colitis in T-cell receptor alpha mutant mice, Gastroenterology 116, 320-6.
-
(1999)
Gastroenterology
, vol.116
, pp. 320-326
-
-
Mizoguchi, A.1
Mizoguchi, E.2
Bhan, A.K.3
-
21
-
-
0032534043
-
A novel model of inflammatory bowel disease: Mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis
-
Panwala, C.M., Jones, J.C., Viney J.L. (1998) A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis, J Immunol 161, 5733-44.
-
(1998)
J Immunol
, vol.161
, pp. 5733-5744
-
-
Panwala, C.M.1
Jones, J.C.2
Viney, J.L.3
-
22
-
-
34047173496
-
Epithelial NEMO links innate immunity to chronic intestinal inflammation
-
Nenci, A., Becker, C., Wullaert, A. et al. (2007) Epithelial NEMO links innate immunity to chronic intestinal inflammation, Nature 446, 557-61.
-
(2007)
Nature
, vol.446
, pp. 557-561
-
-
Nenci, A.1
Becker, C.2
Wullaert, A.3
-
23
-
-
33947573767
-
Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis
-
Zaph, C., Troy, A.E., Taylor, B.C. et al. (2007) Epithelial-cell- intrinsic IKK-beta expression regulates intestinal immune homeostasis, Nature 446, 552-6.
-
(2007)
Nature
, vol.446
, pp. 552-556
-
-
Zaph, C.1
Troy, A.E.2
Taylor, B.C.3
-
24
-
-
33745746660
-
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 Is critical for colonic protection
-
Van der Sluis, M., De Koning, B.A., De Bruijn, A.C. et al. (2006) Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 Is critical for colonic protection, Gastroenterology 131, 117-129.
-
(2006)
Gastroenterology
, vol.131
, pp. 117-129
-
-
Van Der Sluis, M.1
De Koning, B.A.2
De Bruijn, A.C.3
-
25
-
-
41549092745
-
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis
-
doi: 10.1371/journal.pmed.0050054
-
Heazlewood, C.K., Cook, M.C., Eri, R. et al. (2008) Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis, PLoS Med 5, e54. doi: 10.1371/journal.pmed.0050054.
-
(2008)
PLoS Med
, vol.5
-
-
Heazlewood, C.K.1
Cook, M.C.2
Eri, R.3
-
26
-
-
79955106916
-
An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity
-
Eri, R.D., Adams, R.J., Tran, T.V. et al. (2010) An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity, Mucosal Immunol 4, 354-64.
-
(2010)
Mucosal Immunol
, vol.4
, pp. 354-364
-
-
Eri, R.D.1
Adams, R.J.2
Tran, T.V.3
-
27
-
-
66349091311
-
The protein disulfide isomerase AGR2 is essential for production of intestinal mucus
-
Park, S.W., Zhen, G., Verhaeghe, C. et al. (2009) The protein disulfide isomerase AGR2 is essential for production of intestinal mucus, Proc Natl Acad Sci USA 106, 6950-5.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6950-6955
-
-
Park, S.W.1
Zhen, G.2
Verhaeghe, C.3
-
28
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
Kaser, A., Lee, A.H., Franke, A. et al. (2008) XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease, Cell 134, 743-56.
-
(2008)
Cell
, vol.134
, pp. 743-756
-
-
Kaser, A.1
Lee, A.H.2
Franke, A.3
-
29
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell, K., Liu, J.Y., Brown, S. L. et al. (2008) A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells, Nature 456, 259-63.
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
|