The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification

Cell

Volumn 109, Issue 1, 2002, Pages 61-73

  Zhou, Qiao ^a   Anderson, David J ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL TYPE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EMBRYO; GENE; GLIA; INTERNEURON; MOTONEURON; MOUSE; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN DOMAIN; SPINAL CORD;

ANIMALIA;

EID: 0037023492     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00677-3     Document Type: Article

References (53)

1. Stem cells and pattern formation in the nervous system: The possible versus the actual
2. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
3. A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
4. The Phox2b transcription factor coordinately regulates neuronal cell cycle exit and identity
5. Generation of neurons by transient expression of neural bHLH proteins in mammalian cells
6. The function of hairy-related bHLH repressor proteins in cell fate decisions
7. rax, Hes1, and notch1 promote the formation of Muller glia by postnatal retinal progenitor cells
8. Mammalian neural stem cells
9. Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors
10. Spinal cord oligodendrocytes develop from ventrally derived progenitor cells that express PDGF alpha-receptors
11. Dorsoventral patterning and oligodendroglial specification in the developing central nervous system
12. Glial cell fate specification modulated by the bHLH gene Hes5 in mouse retina
13. Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects
14. Neuronal specification in the spinal cord: Inductive signals and transcriptional codes
15. Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors
16. Histon-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells
17. Coordinate roles for Lim homeobox genes in directing the dorsoventral trajectory of motor axons in the vertebrate limb
18. Lineage, arrangement, and death of clonally related motorneurons in chick spinal cord
19. Basic helix-loop-helix genes in neural development
20. Functionally-related motor neuron pool and muscle sensory afferent subtypes defined by coordinate ETS gene expression
21. Comparison of the generic neuronal differentiation and neuron subtype specification functions of mammalian achaete-scute and atonal homologs in cultured neural progenitor cells
22. Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system
23. Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex
24. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection
25. Cell lineage in the cerebral cortex of the mouse studied in vivo and in vitro with a recombinant retrovirus
26. Identification of neurogenin, a vertebrate neuronal determination gene
27. neuroD2 and neuroD3: Distinct expression patterns and transcriptional activation potentials within the neuroD gene family
28. Oligodendrocyte origins
29. Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons
30. Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the vertral neural tube
31. Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors
32. Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2
33. Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity
34. Requirement for LIM homeobox gene Isl1 in motor-neuron generation reveals a motor neuron-dependent step in interneuron differentiation
35. Dorsal spinal cord neuroepithelium generates astrocytes but not oligodendrocytes
36. Glial cell diversification in the rat optic nerve
37. Origins of spinal cord oligodendrocytes: Possible developmental and evolutionary relationships with motor neurons
38. Oligodendrocyte lineage and the motor neuron connection
39. The basic Helix-Loop-Helix gene Hesr2 promotes gliogenesis in mouse retina
40. Crossregulation between Neurogenin2 and pathways specifying neuronal identity in the spinal cord
41. LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons
42. Pax6 influences the time and site of origin of glial precursors in the ventral neural tube
43. Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube
44. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms
45. Dynamic expression of basic helix-loop-helix Olig family members: Implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3
46. Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system
47. Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes
48. Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification
49. A turn of the helix: Preventing the glial fate
50. The MyoD family and myogenesis: Redundancy, networks and thresholds
51. Oligodendrocyte development in the spinal cord and telencephalon: Common themes and new perspectives
52. Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors
53. The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2