Saucerneol F, a new lignan, inhibits iNOS expression via MAPKs, NF-κB and AP-1 inactivation in LPS-induced RAW264.7 cells

International Immunopharmacology

Volumn 12, Issue 1, 2012, Pages 175-181

  Lu, Yue ^a   Suh, Seok Jong ^a   Kwak, Choong Hwan ^b   Kwon, Kyung Min ^b   Seo, Chang Seob ^c   Li, Ying ^a   Jin, Ye ^a   Li, Xian ^a   Hwang, Seung Lark ^a   Kwon, Okyun ^a   Chang, Young Chae ^d   Park, Young Guk ^e   Park, Sung Soo ^f   Son, Jong Keun ^a   Kim, Cheorl Ho ^b   Chang, Hyeun Wook ^a  

^a Yeungnam University   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^d Catholic University of Daegu   (South Korea)

^e Kyung Hee University   (South Korea)

^f Cheju Halla University   (South Korea)

Author keywords

iNOS; Lipopolysaccharide; MAPKs; NF B; Saucerneol F; Saururus chinensis

Indexed keywords

ANTIINFLAMMATORY AGENT; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIGNAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; SAUCERNEOL F; SAURURUS CHINENSIS EXTRACT; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG ISOLATION; GENE ACTIVITY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; I-KAPPA B KINASE; LIGNANS; LIPOPOLYSACCHARIDES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RNA, MESSENGER; SAURURACEAE; TRANSCRIPTION FACTOR AP-1;

EID: 84856093430     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.11.008     Document Type: Article

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