Inhibition of DNA topoisomerases i and II and cytotoxicity by lignans from Saururus chinensis

Archives of Pharmacal Research

Volumn 32, Issue 10, 2009, Pages 1409-1415

  Lee, Yeun Kyung ^a   Seo, Chang Seob ^a,b   Lee, Chong Soon ^a   Lee, Kyong Seon ^c   Kang, Shin Jung ^d   Jahng, Yurngdong ^a   Chang, Hyun Wook ^a   Son, Jong Keun ^a  

^a Yeungnam University   (South Korea)

^b Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Korea Food and Drug Administration   (South Korea)

Author keywords

Cytotoxicity; Lignan; Saururaceae; Saururus chinensis; Topoisomerase

Indexed keywords

1' EPI SAUCHINONE; ACETIC ACID ETHYL ESTER; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); ERYTHRO AUSTROBAILIGNAN 6; LIGNAN DERIVATIVE; MACHILIN D; MANASSANTIN A; MANASSANTIN B; MESO DIHYDROGUAIARETIC ACID; NECTANDRIN I; SAUCERNEOL D; SAUCERNEOL F; SAUCERNEOL G; SAUCERNEOL H; SAUCERNEOL I; SAUCHINONE; SAURURUS CHINENSIS EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; CELL STRAIN HT29; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; PLANT; PLANT ROOT; SAURURUS CHINENSIS;

CELL LINE, TUMOR; CELL SURVIVAL; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; HUMANS; LIGNANS; MOLECULAR STRUCTURE; PLANT EXTRACTS; PLANT ROOTS; SAURURACEAE;

EID: 70450188835     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-009-2010-7     Document Type: Article

References (32)

1. S. K. Chattopadhyay K. V. Rao 1987 Chemistry of Saururus cernuus, IV: Cyclooctadiene systems derived from austrobailignan-5 Tetrahedron 43 669 678 10.1016/S0040-4020(01)90001-8 1:CAS:528:DyaL1cXlslKl
2. A. Y. Chen L. F. Liu 1994 DNA topoisomerase: essential enzymes and lethal targets Annu. Rev. Pharmacol. Toxicol. 34 191 218 10.1146/annurev.pa.34.040194. 001203 1:CAS:528:DyaK2cXmt1Sks74%3D 8042851
3. Chung B. S. and Shin M. G., Dictionary of Korean Folk Medicine, Young Lim Sa, Seoul, p. 813 (1990).
4. P. D'Arpa L. F. Liu 1989 Topoisomerase-targeting antitumor drugs Biochim. Biophys. Acta. 989 163 177 2557085
5. F. Filleur J. C. Le Bail J. L. Durous A. Simon A. J. Chulia 2001 Antiproliferative, anti-aromatase, anti-17β-HSD and antioxidant activies of lignans isolated from Myristica argentea Planta Med. 67 700 704 10.1055/s-2001-18349 1:CAS:528:DC%2BD3MXosVylsbg%3D 11731908
6. M. Fukuda K. Nishio F. Kanzawa H. Ogasawara T. Ishida H. Arioka K. Bojamowski M. Oka N. Saijo 1996 Synergism between cisplatin and topoisomerase I inhibitors, NB-506 and SN-38, in human small cell lung cancer cells Cancer Res. 56 789 793 1:CAS:528:DyaK28XhtVClsb4%3D 8631015
7. B. Y. Hwang J. H. Lee J. B. Nam Y. S. Hong J. J. Lee 2003 Lignans from Saururus chinensis inhibiting the transcription factor NF-êB Phytochemistry 64 765 771 10.1016/S0031-9422(03)00391-1 1:CAS:528: DC%2BD3sXnt1yitbY%3D 13679100 (Pubitemid 37176411)
8. B. Y. Hwang J. H. Lee J. B. Nam H. S. Kim Y. S. Hong J. J. Lee 2002 Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor γ J. Nat. Prod. 65 616 617 10.1021/np010440j 1:CAS:528:DC%2BD38XhvFOntrg%3D 11975517 (Pubitemid 34456959)
9. Y. Ikeya I. Taguchi I. Yoshida 1979 The constituents of Schizandra chinensis Baill. IV. The structures of two new lignans, pre-gomisin and gomisin J Chem. Pharm. Bull. 27 1583 1588 1:CAS:528:DyaE1MXlsFChtbw%3D (Pubitemid 9255905)
10. J. Kubanek W. Fenical M. E. Hay P. J. Brown N. Lindquist 2000 Two antifeedant lignans from the freshwater macrophyte Saururus cernuus Phytochemistry 54 281 287 10.1016/S0031-9422(00)00076-5 1:CAS:528: DC%2BD3cXkt1Sjuro%3D 10870182 (Pubitemid 30353703)
11. L. F. Liu 1989 DNA topoisomerase poisons as antitumor drugs Annu. Rev. Biochem. 58 351 375 10.1146/annurev.bi.58.070189.002031 1:CAS:528: DyaL1MXkslSiu70%3D 2549853
12. N. Nakatani K. Ikeda H. Kikuzaki M. Kido Y. Yamaguchi 1988 Diaryldimethylbutane lignans from Myristica argentea and their antimicrobial action against Streptococcus mutans Phytochemistry 27 3127 3129 10.1016/0031-9422(88)80013-X 1:CAS:528:DyaL1MXhslSiurk%3D
13. Y. Pommier 1993 DNA topoisomerase I and II in cancer chemotherapy: update and perspectives Cancer Chemother. Pharmacol. 32 103 108 10.1007/BF00685611 1:CAS:528:DyaK3sXlvFCru7c%3D 8387398
14. M. Potmesil 1994 Camptothecins: from bench research to hospital wards Cancer Res. 54 1431 1439 1:CAS:528:DyaK2cXitVOktbo%3D 8137244
15. I. Rajbhandari S. Takamatsu D. G. Nagle 2001 A new dehydrogeranylgeraniol antioxidant from Saururus cernuus that inhibits intracellular reactive oxygen species (ROS)-catalyzed oxidation within HL-60 cells J. Nat. Prod. 64 693 695 10.1021/np0101346 1:CAS:528:DC%2BD3MXjvVOgsbY%3D 11421725 (Pubitemid 32565911)
16. K. V. Rao F. M. Alvarez 1982 Chemistry of Saururus cernuus. I. Saucernetin, a new neolignan J. Nat. Prod. 45 393 397 10.1021/np50022a005 1:CAS:528:DyaL38Xlslyks74%3D (Pubitemid 13252725)
17. K. V. Rao F. M. Alvarez 1985 Chemistry of Saururus cernuus III: Some reactions the diarylbutane-type neolignans J. Nat. Prod. 48 592 597 10.1021/np50040a012 1:CAS:528:DyaL28XmvVKltg%3D%3D
18. K. V. Rao F. M. Alvarez 1983 Manassantins A/B and saucerneol: novel biologically active lignoids from Saururus cernuus Tetrahedron Lett. 24 4947 4950 10.1016/S0040-4039(01)99818-1 1:CAS:528:DyaL2cXkvVGltg%3D%3D
19. K. V. Rao V. N. Puri P. K. Diwan F. M. Alvarez 1987 Preliminary evaluation of manassantin A, a potential neuroleptic agent from Saururus cernuus Pharmacol. Res. Commun. 19 629 638 10.1016/0031-6989(87)90117-2 1:CAS:528:DyaL1cXjtFynsQ%3D%3D 2893391
20. K. V. Rao N. S. P. Rao 1990 Chemistry of Saururus cernuus, VI: Three new neolignans J. Nat. Prod. 53 212 215 10.1021/np50067a036 1:CAS:528: DyaK3cXltFant7o%3D 2161446 (Pubitemid 20152067)
21. K. V. Rao G. C. S. Reddy 1990 Chemistry of Saururus cernuus, V. Sauristolactam and other nitrogenous constituents J. Nat. Prod. 53 309 312 10.1021/np50068a006 1:CAS:528:DyaK3cXkslCrs7o%3D 2380708 (Pubitemid 20202667)
22. K. V. Rao R. S. Oruganty 1997 An improved method for the isolation of the lignan constituents of Saururus cernuus by reverse phase column chromatography J. Liq. Chrom. & Rel. Technol. 20 3121 3134 10.1080/10826079708000478 1:CAS:528:DyaK2sXntFCntr0%3D
23. L. V. Rubinstein R. H. Shoemaker K. D. Paul R. M. Simon S. Tosini P. Skehan D. A. Scudiero A. Monks M. R. Boyd 1990 Comparison of in vitro anticancer drug screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines J. Nat. Cancer Inst. 82 1113 1118 10.1093/jnci/82.13.1113 1:CAS:528:DyaK3cXltVylsLw%3D 2359137
24. C. S. Seo Y. K. Lee Y. J. Kim J. S. Jung Y. D. Jahng H. W. Chang D. K. Song J. K. Son 2008 Protective effect of lignans against sepsis from the roots of Saururus chinensis Biol. Pharm. Bull. 31 523 526 10.1248/bpb.31.523 1:CAS:528:DC%2BD1cXmtlaktLc%3D 18310923
25. C. S. Seo M. S. Zheng M. H. Woo C. S. Lee S. H. Lee B. S. Jeong H. W. Chang Y. D. Jahng E. S. Lee J. K. Son 2008 Lignans from the roots of Saururus chinensis J. Nat. Prod. 71 1771 1774 10.1021/np8002723 1:CAS:528: DC%2BD1cXht1WlsbnF 18841903
26. H. Shimomura Y. Sashida M. Oohara 1987 Lignans from Machilus thunbergii Phytochemistry 26 1513 1515 10.1016/S0031-9422(00)81847-6 1:CAS:528: DyaL2sXltlSrur0%3D
27. H. Shimomura Y. Sashida M. Oohara 1988 Lignans from Machilus thunbergii Phytochemistry 27 634 636 10.1016/0031-9422(88)83162-5 1:CAS:528: DyaL1cXitVWksrk%3D
28. W. J. Slichenmyer E. K. Rowinsky R. C. Donehower S. H. Kaufmann 1993 The current status of camptothecin analogues as antitumor agents J. Natl. Cancer Inst. 85 271 291 10.1093/jnci/85.4.271 1:CAS:528:DyaK3sXit1CksL0%3D 8381186
29. S. H. Sung Y. C. Kim 2000 Hepatoprotective diastereomeric lignans from Saururus chinensis herbs J. Nat. Prod. 63 1019 1021 10.1021/np990499e 1:CAS:528:DC%2BD3cXjt1eltLY%3D 10924192 (Pubitemid 30624498)
30. S. H. Sung S. H. Kwon N. J. Cho Y. C. Kim 1997 Hepatoprotective flavonol glycosides of Saururus chinensis herbs Phytother. Res. 11 500 503 10.1002/(SICI)1099-1573(199711)11:7<500::AID-PTR139>3.0.CO;2-P 1:CAS:528:DyaK2sXntlSrsb4%3D (Pubitemid 27460631)
31. E. C. Wang M. H. Shih M. C. Liu M. T. Chen G. H. Lee 1996 Studies on constituents of Saururus chinensis Heterocycles 43 969 975 10.3987/COM-95-7370 1:CAS:528:DyaK28XjtlGmtL0%3D
32. J. C. Wang 1996 DNA topoisomerases Annu. Rev. Biochem. 65 635 692 10.1146/annurev.bi.65.070196.003223 1:CAS:528:DyaK28XktFamur0%3D 8811192