Functional magnetic resonance imaging of semantic memory as a presymptomatic biomarker of Alzheimer's disease risk

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1822, Issue 3, 2012, Pages 442-456

  Sugarman, Michael A ^a   Woodard, John L ^a   Nielson, Kristy A ^b,c   Seidenberg, Michael ^d   Smith, J Carson ^c,e   Durgerian, Sally ^c   Rao, Stephen M ^f  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Marquette University   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^e UNIVERSITY OF MARYLAND   (United States)

^f LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Alzheimer's disease; Cognitive decline; FMRI; Person identification; Prediction; Semantic memory

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E EPSILON 4; BIOLOGICAL MARKER; BRAIN DERIVED NEUROTROPHIC FACTOR; UNCLASSIFIED DRUG;

AGING; ALZHEIMER DISEASE; AMNESIA; ASYMPTOMATIC DISEASE; BRAIN FUNCTION; CLINICAL ASSESSMENT; COGNITION; DEMENTIA; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; EPISODIC MEMORY; EVIDENCE BASED MEDICINE; FACE; FACIAL EXPRESSION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HISTOPATHOLOGY; HUMAN; IMAGE RETRIEVAL; MILD COGNITIVE IMPAIRMENT; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; PHYSICAL ACTIVITY; POSITRON EMISSION TOMOGRAPHY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; RECOGNITION; REVIEW; RISK FACTOR; SEMANTIC MEMORY; SYNAPTOGENESIS; TASK PERFORMANCE;

ALZHEIMER DISEASE; BIOLOGICAL MARKERS; HUMANS; MAGNETIC RESONANCE IMAGING; MEMORY; PREDICTIVE VALUE OF TESTS; RISK FACTORS; SEMANTICS;

EID: 84856031334     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2011.09.016     Document Type: Review

References (171)

1. Brookmeyer R., Johnson E., Ziegler-Graham K., Arrighi H.M. Forecasting the global burden of Alzheimer's disease. Alzheimers Dement. 2007, 3:186-191.
2. Sloane P.D., Zimmerman S., Suchindran C., Reed P., Wang L., Boustani M., Sudha S. The public health impact of Alzheimer's disease, 2000-2050: potential implication of treatment advances. Annu. Rev. Public Health 2002, 23:213-231.
3. Daviglus M.L., Bell C.C., Berrettini W., Bowen P.E., Connolly E.S., Cox N.J., Dunbar-Jacob J.M., Granieri E.C., Hunt G., McGarry K., Patel D., Potosky A.L., Sanders-Bush E., Silberberg D., Trevisan M. National Institutes of Health State-of-the-Science Conference statement: preventing alzheimer disease and cognitive decline. Ann. Intern. Med. 2010, 153:176-181.
4. Gu Y., Nieves J.W., Stern Y., Luchsinger J.A., Scarmeas N. Food combination and Alzheimer disease risk: a protective diet. Arch. Neurol. 2010, 67:699-706.
5. Rolland Y., Abellan van Kan G., Vellas B. Physical activity and Alzheimer's disease: from prevention to therapeutic perspectives. J. Am. Med. Dir. Assoc. 2008, 9:390-405.
6. Fratiglioni L., Paillard-Borg S., Winblad B. An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol. 2004, 3:343-353.
7. Saczynski J.S., Pfeifer L.A., Masaki K., Korf E.S., Laurin D., White L., Launer L.J. The effect of social engagement on incident dementia: the Honolulu-Asia Aging Study. Am. J. Epidemiol. 2006, 163:433-440.
8. Wilson R.S., Scherr P.A., Schneider J.A., Tang Y., Bennett D.A. Relation of cognitive activity to risk of developing Alzheimer disease. Neurology 2007, 69:1911-1920.
9. Wilson R.S., Bennett D.A., Bienias J.L., Aggarwal N.T., Mendes De Leon C.F., Morris M.C., Schneider J.A., Evans D.A. Cognitive activity and incident AD in a population-based sample of older persons. Neurology 2002, 59:1910-1914.
10. Kok E., Haikonen S., Luoto T., Huhtala H., Goebeler S., Haapasalo H., Karhunen P.J. Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age. Ann. Neurol. 2009, 65:650-657.
11. Ghebremedhin E., Schultz C., Braak E., Braak H. High frequency of apolipoprotein E epsilon4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes. Exp. Neurol. 1998, 153:152-155.
12. Fratiglioni L., Ahlbom A., Viitanen M., Winblad B. Risk factors for late-onset Alzheimer's disease: a population-based, case-control study. Ann. Neurol. 1993, 33:258-266.
13. Bertram L., Tanzi R.E. Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses. Nat. Rev. Neurosci. 2008, 9:768-778.
14. Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993, 261:921-923.
15. Saunders A.M., Strittmatter W.J., Schmechel D., George-Hyslop P.H.St., Pericak-Vance M.A., Joo S.H., Rosi B.L., Gusella J.F., Crapper-MacLachlan D.R., Alberts M.J., Hulette C., Crain B., Goldgaber D., Roses A.D. Association of apolipoprotein E allele e4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993, 43:1467-1472.
16. Clark C.M., Davatzikos C., Borthakur A., Newberg A., Leight S., Lee V.M., Trojanowski J.Q. Biomarkers for early detection of Alzheimer pathology. Neurosignals 2008, 16:11-18.
17. Brys M., Pirraglia E., Rich K., Rolstad S., Mosconi L., Switalski R., Glodzik-Sobanska L., De Santi S., Zinkowski R., Mehta P., Pratico D., Saint Louis L.A., Wallin A., Blennow K., de Leon M.J. Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment. Neurobiol. Aging 2009, 30:682-690.
18. de Leon M.J., DeSanti S., Zinkowski R., Mehta P.D., Pratico D., Segal S., Rusinek H., Li J., Tsui W., Saint Louis L.A., Clark C.M., Tarshish C., Li Y., Lair L., Javier E., Rich K., Lesbre P., Mosconi L., Reisberg B., Sadowski M., DeBernadis J.F., Kerkman D.J., Hampel H., Wahlund L.O., Davies P. Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment. Neurobiol. Aging 2006, 27:394-401.
19. de Leon M.J., Mosconi L., Li J., De Santi S., Yao Y., Tsui W.H., Pirraglia E., Rich K., Javier E., Brys M., Glodzik L., Switalski R., Saint Louis L.A., Pratico D. Longitudinal CSF isoprostane and MRI atrophy in the progression to AD. J. Neurol. 2007, 254:1666-1675.
20. Buerger K., Teipel S.J., Zinkowski R., Blennow K., Arai H., Engel R., Hofmann-Kiefer K., McCulloch C., Ptok U., Heun R., Andreasen N., DeBernardis J., Kerkman D., Moeller H., Davies P., Hampel H. CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects. Neurology 2002, 59:627-629.
21. Buerger K., Zinkowski R., Teipel S.J., Tapiola T., Arai H., Blennow K., Andreasen N., Hofmann-Kiefer K., DeBernardis J., Kerkman D., McCulloch C., Kohnken R., Padberg F., Pirttila T., Schapiro M.B., Rapoport S.I., Moller H.J., Davies P., Hampel H. Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231. Arch. Neurol. 2002, 59:1267-1272.
22. Hampel H., Buerger K., Zinkowski R., Teipel S.J., Goernitz A., Andreasen N., Sjoegren M., DeBernardis J., Kerkman D., Ishiguro K., Ohno H., Vanmechelen E., Vanderstichele H., McCulloch C., Moller H.J., Davies P., Blennow K. Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study. Arch. Gen. Psychiatry 2004, 61:95-102.
23. Hampel H., Teipel S.J., Fuchsberger T., Andreasen N., Wiltfang J., Otto M., Shen Y., Dodel R., Du Y., Farlow M., Moller H.J., Blennow K., Buerger K. Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment. Mol. Psychiatry 2004, 9:705-710.
24. Blennow K., Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurol. 2003, 2:605-613.
25. Hansson O., Zetterberg H., Buchhave P., Londos E., Blennow K., Minthon L. Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study. Lancet Neurol. 2006, 5:228-234.
26. de Leon M.J., George A.E., Stylopoulos L.A., Smith G., Miller D.C. Early marker for Alzheimer's disease: the atrophic hippocampus. Lancet 1989, 2:672-673.
27. Jack C.R., Petersen R.C., Xu Y.C., O'Brien P.C., Smith G.E., Ivnik R.J., et al. Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment. Neurology 1999, 52:1397-1403.
28. Wolf H., Jelic V., Gertz H.J., Nordberg A., Julin P., Wahlund L.O. A critical discussion of the role of neuroimaging in mild cognitive impairment. Acta Neurol. Scand. Suppl. 2003, 179:52-76.
29. Henneman W.J., Sluimer J.D., Barnes J., van der Flier W.M., Sluimer I.C., Fox N.C., Scheltens P., Vrenken H., Barkhof F. Hippocampal atrophy rates in Alzheimer disease: added value over whole brain volume measures. Neurology 2009, 72:999-1007.
30. Morra J.H., Tu Z., Apostolova L.G., Green A.E., Avedissian C., Madsen S.K., Parikshak N., Hua X., Toga A.W., Jack C.R., Schuff N., Weiner M.W., Thompson P.M. Automated 3D mapping of hippocampal atrophy and its clinical correlates in 400 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. Hum. Brain Mapp. 2009, 30:2766-2788.
31. Stoub T.R., Rogalski E.J., Leurgans S., Bennett D.A., Detoledo-Morrell L. Rate of entorhinal and hippocampal atrophy in incipient and mild AD: relation to memory function. Neurobiol. Aging 2008, 31:1089-1098.
32. Cardenas V.A., Du A.T., Hardin D., Ezekiel F., Weber P., Jagust W.J., Chui H.C., Schuff N., Weiner M.W. Comparison of methods for measuring longitudinal brain change in cognitive impairment and dementia. Neurobiol. Aging 2003, 24:537-544.
33. Devanand D.P., Pradhaban G., Liu X., Khandji A., De Santi S., Segal S., Rusinek H., Pelton G.H., Honig L.S., Mayeux R., Stern Y., Tabert M.H., de Leon M.J. Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology 2007, 68:828-836.
34. Juottonen K., Lehtovirta M., Helisalmi S., Riekkinen P.J., Soininen H. Major decrease in the volume of the entorhinal cortex in patients with Alzheimer's disease carrying the apolipoprotein E epsilon4 allele. J. Neurol. Neurosurg. Psychiatry 1998, 65:322-327.
35. Jelic V., Johansson S.E., Almkvist O., Shigeta M., Julin P., Nordberg A., Winblad B., Wahlund L.O. Quantitative electroencephalography in mild cognitive impairment: longitudinal changes and possible prediction of Alzheimer's disease. Neurobiol. Aging 2000, 21:533-540.
36. Buscema M., Grossi E., Capriotti M., Babiloni C., Rossini P. The I.F.A.S.T. model allows the prediction of conversion to Alzheimer disease in patients with mild cognitive impairment with high degree of accuracy. Curr. Alzheimer Res. 2010, 7:173-187.
37. Chetelat G., Eustache F., Viader F., De la Sayette V., Pelerin A., Mezenge F., Hannequin D., Dupuy B., Baron J.D., Desgranges B. FDG-PET measurement is more accurate than neuropsychological assessments to predict global cognitive deterioration in patients with mild cognitive impairment. Neurocase 2005, 11:14-25.
38. Chetelat G., Desgranges B., De La Sayette V., Viader F., Eustache F., Baron J.C. Mild cognitive impairment: can FDG-PET predict who is to rapidly convert to Alzheimer's disease?. Neurology 2003, 60:1374-1377.
39. Drzezga A., Grimmer T., Riemenschneider M., Lautenschlager N., Siebner H., Alexopoulus P., Minoshima S., Schwaiger M., Kurz A. Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET. J. Nucl. Med. 2005, 46:1625-1632.
40. Wolk D.A., Klunk W. Update on amyloid imaging: from healthy aging to Alzheimer's disease. Curr. Neurol. Neurosci. Rep. 2009, 9:345-352.
41. Wolk D.A., Price J.C., Saxton J.A., Snitz B.E., James J.A., Lopez O.L., Aizenstein H.J., Cohen A.D., Weissfeld L.A., Mathis C.A., Klunk W.E., De-Kosky S.T. Amyloid imaging in mild cognitive impairment subtypes. Ann. Neurol. 2009, 65:557-568.
42. Rowe C.C., Ng S., Ackermann U., Gong S.J., Pike K., Savage G., Cowie T.F., Dickinson K.L., Maruff P., Darby D., Smith C., Woodward M., Merory J., Tochon-Danguy H., O'Keefe G., Klunk W.E., Mathis C.A., Price J.C., Masters C.L., Villemagne V.L. Imaging beta-amyloid burden in aging and dementia. Neurology 2007, 68:1718-1725.
43. Miller S.L., Fenstermacher E., Bates J., Blacker D., Sperling R.A., Dickerson B.C. Hippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline. J. Neurol. Neurosurg. Psychiatry 2008, 79:630-635.
44. Vannini P., Almkvist O., Dierks T., Lehmann C., Wahlund L.O. Reduced neuronal efficacy in progressive mild cognitive impairment: a prospective fMRI study on visuospatial processing. Psychiatry Res. 2007, 156:43-57.
45. Petrella J.R., Prince S.E., Wang L., Hellegers C., Doraiswamy P.M. Prognostic value of posteromedial cortex deactivation in mild cognitive impairment. PLoS One 2007, 2:e1104.
46. Bookheimer S.Y., Strojwas M.H., Cohen M.S., Saunders A.M., Pericak-Vance M.A., Mazziotta J.C., Small G.W. Patterns of brain activation in people at risk for Alzheimer's disease. N. Engl. J. Med. 2000, 343:450-456.
47. Lind J., Ingvar M., Persson J., Sleegers K., Van Broeckhoven C., Adolfsson R., Nilsson L.G., Nyberg L. Parietal cortex activation predicts memory decline in apolipoprotein E-epsilon4 carriers. Neuroreport 2006, 17:1683-1686.
48. Woodard J.L., Seidenberg M., Nielson K.A., Smith J.C., Antuono P., Durgerian S., Guidotti L., Zhang Q., Butts A., Hantke N., Lancaster M., Rao S.M. Prediction of cognitive decline in healthy older adults using fMRI. J. Alzheimers Dis. 2010, 21:871-885.
49. Persson J., Nyberg L., Lind J., Larsson A., Nilsson L.G., Ingvar M., Buckner R.L. Structure-function correlates of cognitive decline in aging. Cereb. Cortex 2006, 16:907-915.
50. O'Brien J.L., O'Keefe K.M., LaViolette P.S., DeLuca A.N., Blacker D., Dickerson B.C., Sperling R.A. Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline. Neurology 2010, 74:1969-1976.
51. Bondi M.W., Houston W.S., Eyler L.T., Brown G.G. fMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer disease. Neurology 2005, 64:501-508.
52. Seidenberg M., Guidotti L., Nielson K.A., Woodard J.L., Durgerian S., Antuono P., Zhang Q., Rao S.M. Semantic memory activation in individuals at risk for developing Alzheimer disease. Neurology 2009, 73:612-620.
53. A.J. Trachtenberg, N. Filippini, C.E. Mackay, The effects of APOE-epsilon4 on the BOLD response, Neurobiol. Aging (in press).
54. Johnson S.C., Schmitz T.W., Trivedi M.A., Ries M.L., Torgerson B.M., Carlsson C.M., Asthana S., Hermann B.P., Sager M.A. The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activation. J. Neurosci. 2006, 26:6069-6076.
55. Xu G., McLaren D.G., Ries M.L., Fitzgerald M.E., Bendlin B.B., Rowley H.A., Sager M.A., Atwood C., Asthana S., Johnson S.C. The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory. Brain 2009, 132:383-391.
56. Trivedi M.A., Schmitz T.W., Ries M.L., Hess T.M., Fitzgerald M.E., Atwood C.S., Rowley H.A., Asthana S., Sager M.A., Johnson S.C. fMRI activation during episodic encoding and metacognitive appraisal across the lifespan: risk factors for Alzheimer's disease. Neuropsychologia 2008, 46:1667-1678.
57. Filippini N., MacIntosh B.J., Hough M.G., Goodwin G.M., Frisoni G.B., Smith S.M., Matthews P.M., Beckmann C.F., Mackay C.E. Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:7209-7214.
58. Mondadori C.R., de Quervain D.J., Buchmann A., Mustovic H., Wollmer M.A., Schmidt C.F., Boesiger P., Hock C., Nitsch R.M., Papassotiropoulos A., Henke K. Better memory and neural efficiency in young apolipoprotein E epsilon4 carriers. Cereb. Cortex 2007, 17:1934-1947.
59. Nielson K.A., Douville K.L., Seidenberg M., Woodard J.L., Miller S.K., Franczak M., Antuono P., Rao S.M. Age-related functional recruitment for famous name recognition: an event-related fMRI study. Neurobiol. Aging 2006, 27:1494-1504.
60. Woodard J.L., Seidenberg M., Nielson K.A., Antuono P., Guidotti L., Durgerian S., Zhang Q., Lancaster M., Hantke N., Butts A., Rao S.M. Semantic memory activation in amnestic mild cognitive impairment. Brain 2009, 132:2068-2078.
61. Woodard J.L., Seidenberg M., Nielson K.A., Miller S.K., Franczak M., Antuono P., Douville K.L., Rao S.M. Temporally graded activation of neocortical regions in response to memories of different ages. J. Cogn. Neurosci. 2007, 19:1113-1124.
62. Douville K., Woodard J.L., Seidenberg M., Miller S.K., Leveroni C.L., Nielson K.A., Franczak M., Antuono P., Rao S.M. Medial temporal lobe activity for recognition of recent and remote famous names: an event-related fMRI study. Neuropsychologia 2005, 43:693-703.
63. Smith J.C., Nielson K.A., Woodard J.L., Seidenberg M., Durgerian S., Antuono P., Butts A.M., Hantke N.C., Lancaster M.A., Rao S.M. Interactive effects of physical activity and APOE-epsilon4 on BOLD semantic memory activation in healthy elders. Neuroimage 2011, 54:635-644.
64. J.C. Smith, K.A. Nielson, J.L. Woodard, M. Seidenberg, M.D. Werber, S. Durgerian, P. Antuono, A. Butts, N. Hantke, M. Lancaster, S.M. Rao, Does physical activity influence semantic memory activation in amnestic mild cognitive impairment?, Psychiatry Res. 193 (2011) 60-62.
65. Aggarwal N.T., Wilson R.S., Beck T.L., Bienias J.L., Bennett D.A. Mild cognitive impairment in different functional domains and incident Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 2005, 76:1479-1484.
66. Bondi M.W., Kaszniak A.W. Implicit and explicit memory in Alzheimer's disease and Parkinson's disease. J. Clin. Exp. Neuropsychol. 1991, 13:339-358.
67. Irle E., Kaiser P., Naumann-Stoll G. Differential patterns of memory loss in patients with Alzheimer's disease and Korsakoff's disease. Int. J. Neurosci. 1990, 52:67-77.
68. Petersen R.C., Smith G.E., Waring S.C., Ivnik R.J., Tangalos E.G., Kokmen E. Mild cognitive impairment: clinical characterization and outcome [In Process Citation]. Arch. Neurol. 1999, 56:303-308.
69. Petersen R.C., Smith G.E., Ivnik R.J., Kokmen E., Tangalos E.G. Memory function in very early Alzheimer's disease. Neurology 1994, 44:867-872.
70. Petersen R.C., Stevens J.C., Ganguli M., Tangalos E.G., Cummings J.L., Dekosky S.T. Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2001, 56:1133-1142.
71. Nilsson L.G. Memory function in normal aging. Acta Neurol. Scand. Suppl. 2003, 179:7-13.
72. Hodges J.R., Salmon D.P., Butters N. Semantic memory impairment in Alzheimer's disease: failure of access or degraded knowledge?. Neuropsychologia 1992, 30:301-314.
73. Hodges J.R., Salmon D.P., Butters N. Differential impairment of semantic and episodic memory in Alzheimer's and Huntington's diseases: a controlled prospective study. J. Neurol. Neurosurg. Psychiatry 1990, 53:1089-1095.
74. Nebes R.D. Semantic memory in Alzheimer's disease. Psychol. Bull. 1989, 106:377-394.
75. Binder J.R., Desai R.H., Graves W.W., Conant L.L. Where is the semantic system? A critical review and meta-analysis of 120 functional neuroimaging studies. Cereb. Cortex 2009, 19:2767-2796.
76. Buckner R.L., Snyder A.Z., Shannon B.J., LaRossa G., Sachs R., Fotenos A.F., Sheline Y.I., Klunk W.E., Mathis C.A., Morris J.C., Mintun M.A. Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J. Neurosci. 2005, 25:7709-7717.
77. Daselaar S.M., Veltman D.J., Rombouts S.A., Raaijmakers J.G., Lazeron R.H., Jonker C. Medial temporal lobe activity during semantic classification using a flexible fMRI design. Behav. Brain Res. 2002, 136:399-404.
78. Otten L.J., Rugg M.D. Task-dependency of the neural correlates of episodic encoding as measured by fMRI. Cereb. Cortex 2001, 11:1150-1160.
79. Kuchinke L., Jacobs A.M., Grubich C., Vo M.L., Conrad M., Herrmann M. Incidental effects of emotional valence in single word processing: an fMRI study. Neuroimage 2005, 28:1022-1032.
80. Fiebach C.J., Friederici A.D., Muller K., von Cramon D.Y. fMRI evidence for dual routes to the mental lexicon in visual word recognition. J. Cogn. Neurosci. 2002, 14:11-23.
81. Prince S.E., Tsukiura T., Cabeza R. Distinguishing the neural correlates of episodic memory encoding and semantic memory retrieval. Psychol. Sci. 2007, 18:144-151.
82. Wagner A.D., Pare-Blagoev E.J., Clark J., Poldrack R.A. Recovering meaning: left prefrontal cortex guides controlled semantic retrieval. Neuron 2001, 31:329-338.
83. Sabsevitz D.S., Medler D.A., Seidenberg M., Binder J.R. Modulation of the semantic system by word imageability. Neuroimage 2005, 27:188-200.
84. Binder J.R., Westbury C.F., McKiernan K.A., Possing E.T., Medler D.A. Distinct brain systems for processing concrete and abstract concepts. J. Cogn. Neurosci. 2005, 17:905-917.
85. Sergent J., Ohta S., MacDonald B. Functional neuroanatomy of face and object processing. A positron emission tomography study. Brain 1992, 115(Pt 1):15-36.
86. Kapur N., Friston K.J., Young A., Frith C.D., Frackowiak R.S. Activation of human hippocampal formation during memory for faces: a PET study. Cortex 1995, 31:99-108.
87. Gorno-Tempini M.L., Price C.J., Josephs O., Vandenberghe R., Cappa S.F., Kapur N., Frackowiak R.S.J. The neural systems sustaining face and proper-name processing. Brain 1998, 121:2103-2118.
88. Bernard F.A., Bullmore E.T., Graham K.S., Thompson S.A., Hodges J.R., Fletcher P.C. The hippocampal region is involved in successful recognition of both remote and recent famous faces. Neuroimage 2004, 22:1704-1714.
89. Elfgren C., van Westen D., Passant U., Larsson E.M., Mannfolk P., Fransson P. fMRI activity in the medial temporal lobe during famous face processing. Neuroimage 2006, 30:609-616.
90. Haist F., Bowden Gore J., Mao H. Consolidation of human memory over decades revealed by functional magnetic resonance imaging. Nat. Neurosci. 2001, 4:1139-1145.
91. Sugiura M., Sassa Y., Watanabe J., Akitsuki Y., Maeda Y., Matsue Y., Fukuda H., Kawashima R. Cortical mechanisms of person representation: recognition of famous and personally familiar names. Neuroimage 2006, 31:853-860.
92. Leveroni C.L., Seidenberg M., Mayer A.R., Mead L.A., Binder J.R., Rao S.M. Neural systems underlying the recognition of familiar and newly learned faces. J. Neurosci. 2000, 20:878-886.
93. Squire L.R., Alvarez P. Retrograde amnesia and memory consolidation: a neurobiological perspective. Curr. Opin. Neurobiol. 1995, 5:169-177.
94. Nadel L., Moscovitch M. Memory consolidation, retrograde amnesia and the hippocampal complex. Curr. Opin. Neurobiol. 1997, 7:217-227.
95. Kobayashi Y., Amaral D.G. Macaque monkey retrosplenial cortex: II. Cortical afferents. J. Comp. Neurol. 2003, 466:48-79.
96. Morris R., Petrides M., Pandya D.N. Architecture and connections of retrosplenial area 30 in the rhesus monkey. Eur. J. Neurosci. 1999, 11:2506-2518.
97. Suzuki W.A., Amaral D.G. Perirhinal and parahippocampal cortices of the macaque monkey: cortical afferents. J. Comp. Neurol. 1994, 350:497-533.
98. Vincent J.L., Kahn I., Van Essen D.C., Buckner R.L. Functional connectivity of the macaque posterior parahippocampal cortex. J. Neurophysiol. 2010, 103:793-800.
99. Wagner A.D., Shannon B.J., Kahn I., Buckner R.L. Parietal lobe contributions to episodic memory retrieval. Trends Cogn. Sci. 2005, 9:445-453.
100. Chetelat G., Desgranges B., de la Sayette V., Viader F., Berkouk K., Landeau B., et al. Dissociating atrophy and hypometabolism impact on episodic memory in mild cognitive impairment. Brain 2003, 126:1955-1967.
101. Minoshima S., Giordani B., Berent S., Frey K.A., Foster N.L., Kuhl D.E. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Ann. Neurol. 1997, 42:85-94.
102. Valla J., Berndt J.D., Gonzalez-Lima F. Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: superficial laminar cytochrome oxidase associated with disease duration. J. Neurosci. 2001, 21:4923-4930.
103. Minoshima S., Foster N.L., Kuhl D.E. Posterior cingulate cortex in Alzheimer's disease. Lancet 1994, 344:895.
104. Takashima A., Petersson K.M., Rutters F., Tendolkar I., Jensen O., Zwarts M.J., McNaughton B.L., Fernandez G. Declarative memory consolidation in humans: a prospective functional magnetic resonance imaging study. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:756-761.
105. Nielson K.A., Seidenberg M., Woodard J.L., Durgerian S., Zhang Q., Gross W.L., Gander A., Guidotti L.M., Antuono P., Rao S.M. Common neural systems associated with the recognition of famous faces and names: an event-related fMRI study. Brain Cogn. 2010, 72:491-498.
106. Cabeza R. Hemispheric asymmetry reduction in older adults: the HAROLD model. Psychol. Aging 2002, 17:85-100.
107. Park D.C., Reuter-Lorenz P. The adaptive brain: aging and neurocognitive scaffolding. Annu. Rev. Psychol. 2009, 60:173-196.
108. Stebbins G.T., Carrillo M.C., Dorfman J., Dirksen C., Desmond J.E., Turner D.A., Bennett D.A., Wilson R.S., Glover G., Gabrieli J.D. Aging effects on memory encoding in the frontal lobes. Psychol. Aging 2002, 17:44-55.
109. Daselaar S.M., Veltman D.J., Rombouts S.A., Raaijmakers J.G., Jonker C. Deep processing activates the medial temporal lobe in young but not in old adults. Neurobiol. Aging 2003, 24:1005-1011.
110. Cabeza R., Anderson N.D., Locantore J.K., McIntosh A.R. Aging gracefully: compensatory brain activity in high-performing older adults. Neuroimage 2002, 17:1394-1402.
111. Grady C.L., McIntosh A.R., Beig S., Keightley M.L., Burian H., Black S.E. Evidence from functional neuroimaging of a compensatory prefrontal network in Alzheimer's disease. J. Neurosci. 2003, 23:986-993.
112. Han S.D., Houston W.S., Jak A.J., Eyler L.T., Nagel B.J., Fleisher A.S., Brown G.G., Corey-Bloom J., Salmon D.P., Thal L.J., Bondi M.W. Verbal paired-associate learning by APOE genotype in non-demented older adults: fMRI evidence of a right hemispheric compensatory response. Neurobiol. Aging 2007, 28:238-247.
113. Borghesani P.R., Johnson L.C., Shelton A.L., Peskind E.R., Aylward E.H., Schellenberg G.D., Cherrier M.M. Altered medial temporal lobe responses during visuospatial encoding in healthy APOE*4 carriers. Neurobiol. Aging 2008, 29:981-991.
114. Mondadori C.R., de Quervain D.J., Buchmann A., Mustovic H., Wollmer M.A., Schmidt C.F., Boesiger P., Hock C., Nitsch R.M., Papassotiropoulos A., Henke K. Better memory and neural efficiency in young apolipoprotein E epsilon4 carriers. Cereb. Cortex 2007, 17:1934-1947.
115. Bassett S.S., Yousem D.M., Cristinzio C., Kusevic I., Yassa M.A., Caffo B.S., Zeger S.L. Familial risk for Alzheimer's disease alters fMRI activation patterns. Brain 2006, 129:1229-1239.
116. Burggren A.C., Small G.W., Sabb F.W., Bookheimer S.Y. Specificity of brain activation patterns in people at genetic risk for Alzheimer disease. Am. J. Geriatr. Psychiatry 2002, 10:44-51.
117. Lind J., Persson J., Ingvar M., Larsson A., Cruts M., Van Broeckhoven C., Adolfsson R., Backman L., Nilsson L.G., Petersson K.M., Nyberg L. Reduced functional brain activity response in cognitively intact apolipoprotein E epsilon4 carriers. Brain 2006, 129:1240-1248.
118. Persson J., Lind J., Larsson A., Ingvar M., Sleegers K., Van Broeckhoven C., Adolfsson R., Nilsson L.G., Nyberg L. Altered deactivation in individuals with genetic risk for Alzheimer's disease. Neuropsychologia 2008, 46:1679-1687.
119. Bruscoli M., Lovestone S. Is MCI really just early dementia? A systematic review of conversion studies. Int. Psychogeriatr. 2004, 16:129-140.
120. Seidenberg M., Guidotti L., Nielson K.A., Woodard J.L., Durgerian S., Zhang Q., Gander A., Antuono P., Rao S.M. Semantic knowledge for famous names in mild cognitive impairment. J. Int. Neuropsychol. Soc. 2009, 15:9-18.
121. Dudas R.B., Clague F., Thompson S.A., Graham K.S., Hodges J.R. Episodic and semantic memory in mild cognitive impairment. Neuropsychologia 2005, 43:1266-1276.
122. Dickerson B.C., Salat D.H., Greve D.N., Chua E.F., Rand-Giovannetti E., Rentz D.M., Bertram L., Mullin K., Tanzi R.E., Blacker D., Albert M.S., Sperling R.A. Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology 2005, 65:404-411.
123. Celone K.A., Calhoun V.D., Dickerson B.C., Atri A., Chua E.F., Miller S.L., DePeau K., Rentz D.M., Selkoe D.J., Blacker D., Albert M.S., Sperling R.A. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J. Neurosci. 2006, 26:10222-10231.
124. Johnson S.C., Schmitz T.W., Moritz C.H., Meyerand M.E., Rowley H.A., Alexander A.L., Hansen K.W., Gleason C.E., Carlsson C.M., Ries M.L., Asthana S., Chen K., Reiman E.M., Alexander G.E. Activation of brain regions vulnerable to Alzheimer's disease: the effect of mild cognitive impairment. Neurobiol. Aging 2006, 27:1604-1612.
125. Sandstrom C.K., Krishnan S., Slavin M.J., Tran T.T., Doraiswamy P.M., Petrella J.R. Hippocampal atrophy confounds template-based functional MR imaging measures of hippocampal activation in patients with mild cognitive impairment. AJNR Am. J. Neuroradiol. 2006, 27:1622-1627.
126. Trivedi M.A., Murphy C.M., Goetz C., Shah R.C., Gabrieli J.D., Whitfield-Gabrieli S., Turner D.A., Stebbins G.T. fMRI activation changes during successful episodic memory encoding and recognition in amnestic mild cognitive impairment relative to cognitively healthy older adults. Dement. Geriatr. Cogn. Disord. 2008, 26:123-137.
127. Price C.J., Friston K.J. Scanning patients with tasks they can perform. Hum. Brain Mapp. 1999, 8:102-108.
128. Gold B.T., Jiang Y., Jicha G.A., Smith C.D. Functional response in ventral temporal cortex differentiates mild cognitive impairment from normal aging. Hum. Brain Mapp. 2010, 31:1249-1259.
129. Vandenbulcke M., Peeters R., Dupont P., Van Hecke P., Vandenberghe R. Word reading and posterior temporal dysfunction in amnestic mild cognitive impairment. Cereb. Cortex 2007, 17:542-551.
130. Petersen R.C., Doody R., Kurz A., Mohs R.C., Morris J.C., Rabins P.V., et al. Current concepts in mild cognitive impairment. Arch. Neurol. 2001, 58:1985-1992.
131. Sager M.A., Hermann B., La Rue A. Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer's Prevention. J. Geriatr. Psychiatry Neurol. 2005, 18:245-249.
132. Jurica P.J., Leitten C.L., Mattis S. Dementia Rating Scale-2 Professional Manual 2001, Psychological Assessment Resources, Lutz, FL.
133. Mattis S. Dementia Rating Scale: Professional Manual 1988, Psychological Assessment Resources, Odessa, FL.
134. Mattis S. Mental status examination for organic mental syndrome in the elderly patient. Geriatric Psychiatry: A Handbook for Psychiatrists and Primary Care Physicians 1976, 77-121. Grune and Stratton, New York. L. Bellak, T. Karasu (Eds.).
135. Rey A. L'examen clinique en psychologie 1958, Presses Universitaires de France, Paris.
136. N. Hantke, K.A. Nielson, J.L. Woodard, A. Butts, M. Seidenberg, J.C. Smith, S. Durgerian, L. Guidotti, M. Lancaster, M.A. Matthews, M.A. Sugarman, S.M. Rao, in preparation. Comparison of semantic and episodic memory BOLD fMRI activation in predicting cognitive decline in older adults.
137. Lustig C., Snyder A.Z., Bhakta M., O'Brien K.C., McAvoy M., Raichle M.E., Morris J.C., Buckner R.L. Functional deactivations: change with age and dementia of the Alzheimer type. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:14504-14509.
138. Rombouts S.A., Barkhof F., Goekoop R., Stam C.J., Scheltens P. Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study. Hum. Brain Mapp. 2005, 26:231-239.
139. van Praag H., Shubert T., Zhao C., Gage F.H. Exercise enhances learning and hippocampal neurogenesis in aged mice. J. Neurosci. 2005, 25:8680-8685.
140. Farmer J., Zhao X., van Praag H., Wodtke K., Gage F.H., Christie B.R. Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience 2004, 124:71-79.
141. van Praag H., Christie B.R., Sejnowski T.J., Gage F.H. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:13427-13431.
142. van Praag H., Kempermann G., Gage F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 1999, 2:266-270.
143. Fabel K., Wolf S.A., Ehninger D., Babu H., Leal-Galicia P., Kempermann G. Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice. Front. Neurosci. 2009, 3:50.
144. Erickson K.I., Voss M.W., Prakash R.S., Basak C., Szabo A., Chaddock L., Kim J.S., Heo S., Alves H., White S.M., Wojcicki T.R., Mailey E., Vieira V.J., Martin S.A., Pence B.D., Woods J.A., McAuley E., Kramer A.F. Exercise training increases size of hippocampus and improves memory. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:3017-3022.
145. Taylor-Piliae R.E., Haskell W.L., Iribarren C., Norton L.C., Mahbouba M.H., Fair J.M., Hlatky M.A., Go A.S., Fortmann S.P. Clinical utility of the Stanford brief activity survey in men and women with early-onset coronary artery disease. J. Cardiopulm. Rehabil. Prev. 2007, 27:227-232.
146. Taylor-Piliae R.E., Norton L.C., Haskell W.L., Mahbouda M.H., Fair J.M., Iribarren C., Hlatky M.A., Go A.S., Fortmann S.P. Validation of a new brief physical activity survey among men and women aged 60-69years. Am. J. Epidemiol. 2006, 164:598-606.
147. J.L. Woodard, M.A. Sugarman, K.A. Nielson, J.C. Smith, M. Seidenberg, S. Durgerian, A. Butts, N. Hantke, M. Lancaster, M.A. Matthews, S.M. Rao, under review. Lifestyle and genetic contributions to cognitive decline and hippocampal integrity and healthy aging.
148. Schuit A.J., Feskens E.J., Launer L.J., Kromhout D. Physical activity and cognitive decline, the role of the apolipoprotein e4 allele. Med. Sci. Sports Exerc. 2001, 33:772-777.
149. Rovio S., Kareholt I., Helkala E.L., Viitanen M., Winblad B., Tuomilehto J., Soininen H., Nissinen A., Kivipelto M. Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease. Lancet Neurol. 2005, 4:705-711.
150. Etnier J.L., Caselli R.J., Reiman E.M., Alexander G.E., Sibley B.A., Tessier D., McLemore E.C. Cognitive performance in older women relative to ApoE-epsilon4 genotype and aerobic fitness. Med. Sci. Sports Exerc. 2007, 39:199-207.
151. Podewils L.J., Guallar E., Kuller L.H., Fried L.P., Lopez O.L., Carlson M., Lyketsos C.G. Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study. Am. J. Epidemiol. 2005, 161:639-651.
152. Liu Y., Paajanen T., Zhang Y., Westman E., Wahlund L.O., Simmons A., Tunnard C., Sobow T., Mecocci P., Tsolaki M., Vellas B., Muehlboeck S., Evans A., Spenger C., Lovestone S., Soininen H. Analysis of regional MRI volumes and thicknesses as predictors of conversion from mild cognitive impairment to Alzheimer's disease. Neurobiol. Aging 2010, 31:1375-1385.
153. Madsen S.K., Ho A.J., Hua X., Saharan P.S., Toga A.W., Jack C.R., Weiner M.W., Thompson P.M. 3D maps localize caudate nucleus atrophy in 400 Alzheimer's disease, mild cognitive impairment, and healthy elderly subjects. Neurobiol. Aging 2010, 31:1312-1325.
154. Seshadri S., Beiser A., Selhub J., Jacques P.F., Rosenberg I.H., D'Agostino R.B., Wilson P.W., Wolf P.A. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N. Engl. J. Med. 2002, 346:476-483.
155. Clarke R. B-vitamins and prevention of dementia. Proc. Nutr. Soc. 2008, 67:75-81.
156. Brown G.G. Functional magnetic resonance imaging in clinical practice: look before you leap. Neuropsychol. Rev. 2007, 17:103-106.
157. Zou K.H., Greve D.N., Wang M., Pieper S.D., Warfield S.K., White N.S., Manandhar S., Brown G.G., Vangel M.G., Kikinis R., Wells W.M. Reproducibility of functional MR imaging: preliminary results of prospective multi-institutional study performed by Biomedical Informatics Research Network. Radiology 2005, 237:781-789.
158. D'Esposito M., Deouell L.Y., Gazzaley A. Alterations in the BOLD fMRI signal with ageing and disease: a challenge for neuroimaging. Nat. Rev. Neurosci. 2003, 4:863-872.
159. Koppelstaetter F., Poeppel T.D., Siedentopf C.M., Ischebeck A., Verius M., Haala I., Mottaghy F.M., Rhomberg P., Golaszewski S., Gotwald T., Lorenz I.H., Kolbitsch C., Felber S., Krause B.J. Does caffeine modulate verbal working memory processes? An fMRI study. Neuroimage 2008, 39:492-499.
160. Mulderink T.A., Gitelman D.R., Mesulam M.M., Parrish T.B. On the use of caffeine as a contrast booster for BOLD fMRI studies. Neuroimage 2002, 15:37-44.
161. Laurienti P.J., Field A.S., Burdette J.H., Maldjian J.A., Yen Y.F., Moody D.M. Dietary caffeine consumption modulates fMRI measures. Neuroimage 2002, 17:751-757.
162. Tanabe J., Tregellas J.R., Martin L.F., Freedman R. Effects of nicotine on hippocampal and cingulate activity during smooth pursuit eye movement in schizophrenia. Biol. Psychiatry 2006, 59:754-761.
163. Tregellas J.R., Tanabe J.L., Martin L.F., Freedman R. FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia. Am. J. Psychiatry 2005, 162:391-393.
164. Thiel C.M., Zilles K., Fink G.R. Nicotine modulates reorienting of visuospatial attention and neural activity in human parietal cortex. Neuropsychopharmacology 2005, 30:810-820.
165. Bermpohl F., Walter M., Sajonz B., Lucke C., Hagele C., Sterzer P., Adli M., Heinz A., Northoff G. Attentional modulation of emotional stimulus processing in patients with major depression-alterations in prefrontal cortical regions. Neurosci. Lett. 2009, 463:108-113.
166. Grimm S., Beck J., Schuepbach D., Hell D., Boesiger P., Bermpohl F., Niehaus L., Boeker H., Northoff G. Imbalance between left and right dorsolateral prefrontal cortex in major depression is linked to negative emotional judgment: an fMRI study in severe major depressive disorder. Biol. Psychiatry 2008, 63:369-376.
167. Phan K.L., Fitzgerald D.A., Nathan P.J., Tancer M.E. Association between amygdala hyperactivity to harsh faces and severity of social anxiety in generalized social phobia. Biol. Psychiatry 2006, 59:424-429.
168. Domschke K., Braun M., Ohrmann P., Suslow T., Kugel H., Bauer J., Hohoff C., Kersting A., Engelien A., Arolt V., Heindel W., Deckert J. Association of the functional-1019C/G 5-HT1A polymorphism with prefrontal cortex and amygdala activation measured with 3 T fMRI in panic disorder. Int. J. Neuropsychopharmacol. 2006, 9:349-355.
169. Dickie E.W., Brunet A., Akerib V., Armony J.L. An fMRI investigation of memory encoding in PTSD: influence of symptom severity. Neuropsychologia 2008, 46:1522-1531.
170. Hashimoto R., Lee K., Preus A., McCarley R.W., Wible C.G. An fMRI study of functional abnormalities in the verbal working memory system and the relationship to clinical symptoms in chronic schizophrenia. Cereb. Cortex 2010, 20:46-60.
171. Calhoun V.D., Eichele T., Pearlson G. Functional brain networks in schizophrenia: a review. Front. Hum. Neurosci. 2009, 3:17.