Transcriptional gene silencing of HPV16 E6/E7 induces growth inhibition via apoptosis in vitro and in vivo

Gynecologic Oncology

Volumn 124, Issue 2, 2012, Pages 296-302

  Zhou, Jiansong ^a   Peng, Chanjuan ^a   Li, Baohua ^a   Wang, Fenfen ^a   Zhou, Caiyun ^a   Hong, Die ^a   Ye, Feng ^a   Cheng, Xiaodong ^a   Lü, Weiguo ^a   Xie, Xing ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Cervical cancer; E6; E7; HPV16; siRNA

Indexed keywords

PROTEIN E6; PROTEIN E7; PROTEIN P16; PROTEIN P53; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; IMMUNOHISTOCHEMISTRY; IN VIVO GENE TRANSFER; MOUSE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; TUMOR VOLUME; UTERINE CERVIX CANCER;

ANIMALS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; FEMALE; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HUMAN PAPILLOMAVIRUS 16; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS E7 PROTEINS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84856010588     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2011.10.028     Document Type: Article

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