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Volumn 17, Issue 12, 2010, Pages 827-836

Highly potent and specific siRNAs against E6 or E7 genes of HPV16-or HPV18-infected cervical cancers

Author keywords

cervical cancer; E6; E7; HPV; siRNA silencing

Indexed keywords

MESSENGER RNA; SMALL INTERFERING RNA;

EID: 78349311997     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2010.38     Document Type: Article
Times cited : (77)

References (20)
  • 1
    • 33646675570 scopus 로고    scopus 로고
    • Molecular biology of human papillomavirus infection and cervical cancer
    • Doorbar J. Molecular biology of human papillomavirus infection and cervical cancer. Clin Sci 2006; 110: 525-541.
    • (2006) Clin Sci , vol.110 , pp. 525-541
    • Doorbar, J.1
  • 2
    • 33846618247 scopus 로고    scopus 로고
    • A public health approach to cervical cancer control: Considerations of screening and vaccination strategies
    • Goldie S. A public health approach to cervical cancer control: considerations of screening and vaccination strategies. Int J Gynecol Obstet 2006; 94: 95-105.
    • (2006) Int J Gynecol Obstet , vol.94 , pp. 95-105
    • Goldie, S.1
  • 4
    • 0041967157 scopus 로고    scopus 로고
    • Human papillomaviruses: Targeting differentiating epithelial cells for malignant transformation
    • Fehrmann F, Laimins L. Human papillomaviruses: targeting differentiating epithelial cells for malignant transformation. Oncogene 2003; 22: 5201-5207.
    • (2003) Oncogene , vol.22 , pp. 5201-5207
    • Fehrmann, F.1    Laimins, L.2
  • 5
    • 0036849734 scopus 로고    scopus 로고
    • Human papillomavirus immortalization and transformation functions
    • Munger K, Howley P. Human papillomavirus immortalization and transformation functions. Virus Res 2002; 89: 213-228.
    • (2002) Virus Res , vol.89 , pp. 213-228
    • Munger, K.1    Howley, P.2
  • 8
    • 20644448213 scopus 로고    scopus 로고
    • RNA-directed transcriptional gene silencing in mammals
    • Bayne EH, Allshire RC. RNA-directed transcriptional gene silencing in mammals. Trends Genet 2005; 21: 370-373.
    • (2005) Trends Genet , vol.21 , pp. 370-373
    • Bayne, E.H.1    Allshire, R.C.2
  • 9
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • Kim DH, Rossi JR. Strategies for silencing human disease using RNA interference. Genetics 2007; 8: 173-184.
    • (2007) Genetics , vol.8 , pp. 173-184
    • Kim, D.H.1    Rossi, J.R.2
  • 10
    • 39049171519 scopus 로고    scopus 로고
    • New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer
    • Yamato K, Tamada T, Kizaki M, Ui-Tei K, Natori Y, Fujino M et al. New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer. Cancer Gene Ther 2008; 15: 140-153.
    • (2008) Cancer Gene Ther , vol.15 , pp. 140-153
    • Yamato, K.1    Tamada, T.2    Kizaki, M.3    Ui-Tei, K.4    Natori, Y.5    Fujino, M.6
  • 11
    • 33749873618 scopus 로고    scopus 로고
    • Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes
    • Gu W, Putral L, Hengst K, Minto K, Saunders NA, Leggatt G et al. Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes. Cancer Gene Ther 2006; 13: 1023-1032.
    • (2006) Cancer Gene Ther , vol.13 , pp. 1023-1032
    • Gu, W.1    Putral, L.2    Hengst, K.3    Minto, K.4    Saunders, N.A.5    Leggatt, G.6
  • 12
    • 16644366010 scopus 로고    scopus 로고
    • Selective silencing of viral gene E6 and E7 expression in HPV-positive human cervical carcinoma cells using small interfering RNAs
    • Jiang M, Milner J. Selective silencing of viral gene E6 and E7 expression in HPV-positive human cervical carcinoma cells using small interfering RNAs. Methods Mol Biol 2005; 292: 401-420.
    • (2005) Methods Mol Biol , vol.292 , pp. 401-420
    • Jiang, M.1    Milner, J.2
  • 13
    • 55649097304 scopus 로고    scopus 로고
    • Gene silencing with siRNA targeting E6/E7 as a therapeutic intervention in a mouse model of cervical cancer
    • Jonson AL, Rogers LM, Ramakrishnan S, Downs Jr LS. Gene silencing with siRNA targeting E6/E7 as a therapeutic intervention in a mouse model of cervical cancer. Gynecol Oncol 2008; 11: 356-364.
    • (2008) Gynecol Oncol , vol.11 , pp. 356-364
    • Jonson, A.L.1    Rogers, L.M.2    Ramakrishnan, S.3    Downs Jr., L.S.4
  • 14
    • 34648837230 scopus 로고    scopus 로고
    • Silencing of HPV 18 oncoproteins with RNA interference causes growth inhibition of cervical cancer cells
    • Lea JS, Sunaga N, Sato M, Kalahasti G, Miller DS, Minna JD et al. Silencing of HPV 18 oncoproteins with RNA interference causes growth inhibition of cervical cancer cells. Report Sci 2007; 14: 10-18.
    • (2007) Report Sci , vol.14 , pp. 10-18
    • Lea, J.S.1    Sunaga, N.2    Sato, M.3    Kalahasti, G.4    Miller, D.S.5    Minna, J.D.6
  • 15
    • 38649111038 scopus 로고    scopus 로고
    • RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulationof Rb and 53
    • Sima N, Wang W, Kong D, Deng D, Xu Q, Zhou J et al. RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulationof Rb and 53. Apoptosis 2008; 13: 273-280.
    • (2008) Apoptosis , vol.13 , pp. 273-280
    • Sima, N.1    Wang, W.2    Kong, D.3    Deng, D.4    Xu, Q.5    Zhou, J.6
  • 16
    • 54049114742 scopus 로고    scopus 로고
    • Grp78 regulates multiple malignant phenotypes in head-neck cancer and may serve as a molecular target of therapeutic intervention
    • Chiu CC, Lin CY, Lee LY, Chen YJ, Kuo TF, Chang JTC et al. Grp78 regulates multiple malignant phenotypes in head-neck cancer and may serve as a molecular target of therapeutic intervention. Mol Cancer Ther 2008; 7: 2788-2797.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2788-2797
    • Chiu, C.C.1    Lin, C.Y.2    Lee, L.Y.3    Chen, Y.J.4    Kuo, T.F.5    Chang, J.T.C.6
  • 17
    • 0037464486 scopus 로고    scopus 로고
    • Disabled-2 small interfering RNA modulates cellular adhesive function and MAPK activity during megakaryocytic differentiation of K562 cells
    • Tseng CP, Huang CL, Huang CH, Cheng JC, Stem A, Tseng CH et al. Disabled-2 small interfering RNA modulates cellular adhesive function and MAPK activity during megakaryocytic differentiation of K562 cells. FEBS Lett 2003; 541: 21-27.
    • (2003) FEBS Lett , vol.541 , pp. 21-27
    • Tseng, C.P.1    Huang, C.L.2    Huang, C.H.3    Cheng, J.C.4    Stem, A.5    Tseng, C.H.6
  • 18
    • 34548067637 scopus 로고    scopus 로고
    • Differentially expressed genes in radioresistant nasopharyngeal cancer cells: Gp96 and GDF15
    • Chang JTC, Chan SH, Lin CY, Lin TY, Wang HM, Liao CT et al. Differentially expressed genes in radioresistant nasopharyngeal cancer cells: gp96 and GDF15. Mol Cancer Ther 2007; 6: 2271-2279.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2271-2279
    • Jtc, C.1    Chan, S.H.2    Lin, C.Y.3    Lin, T.Y.4    Wang, H.M.5    Liao, C.T.6
  • 19
    • 0037229178 scopus 로고    scopus 로고
    • Endogenous human papillomavirus E6 and E7 Proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells
    • DeFilippis RA, Goodwin EC, Wu L, DiMaio D. Endogenous human papillomavirus E6 and E7 Proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells. J Virol 2003; 77: 1551-1563.
    • (2003) J Virol , vol.77 , pp. 1551-1563
    • Defilippis, R.A.1    Goodwin, E.C.2    Wu, L.3    Dimaio, D.4
  • 20
    • 33646167060 scopus 로고    scopus 로고
    • The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16-or type 18-positive cervical cancer cell lines via translation reinitiation
    • Tang S, Tao M, McCoy Jr JP, Zheng ZM. The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16-or type 18-positive cervical cancer cell lines via translation reinitiation. J Virol 2006; 80: 4249-4263.
    • (2006) J Virol , vol.80 , pp. 4249-4263
    • Tang, S.1    Tao, M.2    McCoy Jr., J.P.3    Zheng, Z.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.