Blockade of dopamine D4 receptors attenuates reinstatement of extinguished nicotine-seeking behavior in rats

Neuropsychopharmacology

Volumn 37, Issue 3, 2012, Pages 685-696

  Yan, Yijin ^a   Pushparaj, Abhiram ^a   Le Strat, Yann ^a   Gamaleddin, Islam ^a   Barnes, Chanel ^b   Justinova, Zuzana ^b,c   Goldberg, Steven R ^b   Le Foll, Bernard ^a,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

dopamine receptor D4; nicotine self administration; receptor antagonist; reinstatement of nicotine seeking behavior; relapse; tobacco smoking

Indexed keywords

3 [[4 (4 CHLOROPHENYL) 1 PIPERAZINYL]METHYL] 1H PYRROLO[2,3 B]PYRIDINE; DOPAMINE 4 RECEPTOR; N [4 (2 CYANOPHENYL) 1 PIPERAZINYLMETHYL] 3 METHYLBENZAMIDE; NICOTINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; ASSOCIATION; CONTROLLED STUDY; DRUG DISCRIMINATION; DRUG SELF ADMINISTRATION; FOOD INTAKE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; RELAPSE; SMOKING; TOBACCO DEPENDENCE;

ANIMALS; BEHAVIOR, ANIMAL; DISCRIMINATION LEARNING; DOPAMINE ANTAGONISTS; DRUG-SEEKING BEHAVIOR; EXTINCTION, PSYCHOLOGICAL; MALE; NICOTINE; PYRIDINES; PYRROLES; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D4; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION;

EID: 84855875930     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.245     Document Type: Article

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