Role of dopamine in the behavioural actions of nicotine related to addiction

European Journal of Pharmacology

Volumn 393, Issue 1-3, 2000, Pages 295-314

  Di Chiara, Gaetano ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Addiction; Dependence; Dopamine; Nicotine; Nucleus accumbens; Prefrontal cortex

Indexed keywords

ALCOHOL; AMPHETAMINE; DOPAMINE RECEPTOR BLOCKING AGENT; DRONABINOL; NICOTINE; OXIDOPAMINE;

AMYGDALOID NUCLEUS; ANIMAL MODEL; ASSOCIATION; BEHAVIOR; BRAIN INJURY; BRAIN REGION; CONFERENCE PAPER; CONTROLLED STUDY; DISCRIMINATION LEARNING; DOPAMINE RELEASE; DOPAMINERGIC TRANSMISSION; DRUG ABUSE; DRUG SELF ADMINISTRATION; HUMAN; LEARNING; LOCOMOTION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; REINFORCEMENT; SMOKING;

BEHAVIOR, ADDICTIVE; DOPAMINE; HUMANS; LEARNING DISORDERS; LOCOMOTION; MOTIVATION; NICOTINE; NICOTINIC AGONISTS; REWARD; TOBACCO USE DISORDER;

EID: 0034732318     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00122-9     Document Type: Conference Paper

References (192)

1. Abercrombie E.A., Keefe K.A., Di Frischia D.A., Zigmond M.J. Differential effect of stress on in vivo dopamine release in striatum, nucleus accumbens and medial frontal cortex. J. Neurochem. 52:1989;1655-1658.
2. Acquas E., Carboni E., Leone P., Di Chiara G. SCH23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine receptor blockade? Psychopharmacology. 99:1989;151-155.
3. 1 receptors blockade stereospecifically impairs the acquisition of drug-conditioned place-preference and place-aversion. Behav. Pharmacol. 5:1994;555-569.
4. Alkondon M., Reinhardt S., Lobron C., Hermsen B., Maelicke A., Albuquerque E.X. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons: II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization. J. Pharmacol. Exp. Ther. 271:1994;494-506.
5. Altman J., Everitt B.J., Glautier S., Markou A., Nutt D., Oretti R., Phillips G.D., Robbins T.W. The biological, social, and clinical bases of drug addiction: commentary and debate. Psychopharmacology. 125:1996;285-345.
6. Diagnostic and Statistical Manual of Mental Disorders. 3rd edn. 1987;American Psychiatric Association, Washington, DC. revised.
7. Diagnostic and Statistical Manual of Mental Disorders. 4th edn. 1994;American Psychiatric Association, Washington, DC.
8. Ando K., Yanagita T. The discriminative stimulus properties of intravenously administered cocaine in rhesus monkeys. Colpaert F.C., Rosecrans J.A. Stimulus Properties of Drugs: Ten Years of Progress. 1978;125-136 Elsevier, Amsterdam.
9. Arroyo-Jimenez M.M., Bourgeois J.-P., Marubio L.M., LeSourd A.M., Ottersenn O.P., Rinvik P., Faire A., Changeux J.-P. Ultrastructural localization of the a4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra. J. Neurosci. 19:1999;6475-6487.
10. Azam L., Castaneda D., Chen Y., Leslie F.M. Expression of neuronal nicotinic acetylcholine receptor subunit mRNAS within rat midbrain. Soc. Neurosci. 25:1999;187.
11. Bardo M.T., Bevins R.A., Klebaur J.E., Crooks P.A., Dwoskin L.P. (-)-Nornicotine partially substitutes for (+)-amphetamine in a drug discrimination paradigm in rats. Pharmacol. Biochem. Behav. 58:1997;1083-1087.
12. Bassareo V., Di Chiara G. Differential influence of associative and nonassociative learning mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli in rats fed ad libitum. J. Neurosci. 17:1997;851-861.
13. Bassareo V., Di Chiara G. Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments. Neuroscience. 89:1999;637-641.
14. Bassareo V., Tanda G., Petromilli P., Giua C., Di Chiara G. Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex. Psychopharmacology. 124:1996;293-299.
15. Bauco P., Wise R.A. Potentiation of lateral hypothalamic and midline mesencephalic brain stimulation reinforcement by nicotine: examination of repeated treatment. J. Pharmacol. Exp. Ther. 271:1994;294-301.
16. Beninger R.J. The role of dopamine in locomotor activity and learning. Brain Res. 6:1983;173-196.
17. Benwell M.E., Balfour D.J., Birrell C.E. Desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine. Br. J. Pharmacol. 144:1995;454-460.
18. Benwell M.E.M., Balfour D.J.K. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. Br. J. Pharmacol. 105:1992;849-856.
19. Bindra D. A motivational view of learning, performance, and behavior modification. Psychol. Rev. 81:1974;199-213.
20. Blackburn J.R., Pfaus J.G., Phillips A.G. Dopamine functions in appetitive and defensive behaviours. Progress in Neurobiology. 39:1992;247-279.
21. Bolles R.C. Reinforcement, expectancy, and learning. Psychol. Rev. 79:1972;394-409.
22. Brioni J.D., Kim D.J., O'Neill A.B., Williams J.E., Decker M.W. Clozapine attenuates the discriminative stimulus properties of (-)-nicotine. Brain Res. 643:1994;1-9.
23. Cadoni C., Di Chiara G. Reciprocal changes in dopamine responsiveness in the nucleus accumbens shell and core and in the dorsal caudate-putamen in rats sensitized to morphine. Neuroscience. 90:1999;447-455.
24. Cadoni C., Di Chiara G. Differential changes in accumbens shell and core dopamine in behavioural sensitization to nicotine. Eur. J. Pharmacol. 2000;. (in press).
25. Cadoni C., Solinos M., Di Chiara G. Psychostimulant sensitization differential changes in accumbal shell and core dopamine. Eur. J. Pharmacol. 388:2000;69-76.
26. Cador M., Robbins T.W., Everitt B.J. Involvement of amygdala in stimulus-reward association: interaction with the ventral striatum. Neuroscience. 30:1989;77-86.
27. Caine S.B., Koob G.F. Effects of mesolimbic dopamine depletion on responding maintained by cocaine and food. J. Exp. Anal. Behav. 61:1994;213-221.
28. Calcagnetti D.J., Schechter M.D. Nicotine place preference using the biased method of conditioning. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 18:1994;925-933.
29. 3 antagonist on drug-induced stimulation of dopamine release. Eur. J. Pharmacol. 164:1989;515-519.
30. 3 receptor antagonists block morphine- and nicotine- but not amphetamine-induced reward. Psychopharmacology. 97:1989;175-178.
31. Carboni E., Bortone L., Giua C., Di Chiara G. Dissociation of physical abstinence signs from changes in extraacellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug Alcohol Depend. 58:2000;93-102.
32. Carboni E., Silvagni A., Rolando M.T.P., Di Chiara G. Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by addictive drugs. J. Neurosci. 2000;. (in press).
33. Carr G.D., Fibiger H.C., Phillips A.G. Conditioned place preference as a measure of drug reward. Liebman J.M., Cooper S.J. The Neuropharmacological Basis of Reward. 1989;264-319 Oxford Univ. Press, New York.
34. Carr G.D., White N.M. The relationship between stereotypy and memory improvement produced by amphetamine. Psychopharmacology. 82:1984;203-209.
35. Carroll M.E., Lac S.T., Asencio M., Keenan R.M. Nicotine dependence in rats. Life Sci. 45:1989;1381-1388.
36. Caulliez R., Meile M.-J., Nicolaidis S. A lateral hypothalamic D1 dopaminergic mechanism in conditioned taste aversion. Brain Res. 729:1996;234-245.
37. Chance W.T., Murfin D., Krynock G.M., Rosecrans J.A. A description of the nicotine stimulus and tests of its generalization to amphetamine. Psychopharmacology. 55:1977;19-26.
38. Chandler C.J., Stolerman I.P. Discriminative stimulus properties of the nicotinic agonist cytisine. Psychopharmacology. 129:1997;257-264.
39. Clarke P.B.S., Fibiger H.C. Apparent absence of nicotine-induced conditioned place preference in rats. Psychopharmacology. 92:1987;84-88.
40. Clarke P.B.S., Fu D.S., Jakubovic A., Fibiger H.C. Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats. J. Pharmacol. Exp. Ther. 246:1988;701-708.
41. Clarke P.B.S., Jakubovic A., Fibiger H.C. Anatomical analysis of the involvement of mesolimbic dopamine in the locomotor stimulant actions of D-amphetamine and apomorphine. Psychopharmacology. 96:1988;511-520.
42. Corrigall W.A. Nicotine self-administration in animal as a dependence model. Nicotine Tob. Res. 1:1999;11-20.
43. Corrigall W.A., Coen K.M. Nicotine maintains self-administration in rats on a limited-access schedule. Psychopharmacology. 99:1989;473-478.
44. Corrigall W.A., Coen K.M. Opiate antagonists reduce cocaine but not nicotine self-administration. Psychopharmacology. 104:1991;167-170.
45. Corrigall W.A., Coen K.M. Selective dopamine antagonists reduce nicotine self-administration. Psychopharmacology. 104:1991;171-176.
46. Corrigall W.A., Coen K.M. Dopamine mechanisms play at best a small role in the nicotine discriminative stimulus. Pharmacol. Biochem. Behav. 48:1994;817-820.
47. 3 antagonists ICS 205-930 and MDL 72222. Pharmacol. Biochem. Behav. 49:1994;67-71.
48. Corrigall W.A., Coen K.M., Adamson K.L. Self-administered nicotine activates the mesolimbic dopamine system through the ventral segmental area. Brain Res. 653:1994;278-284.
49. Corrigall W.A., Franklin K.B., Coen K.M., Clarke P.B. The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology. 107:1992;285-289.
50. Damsma G., Day J., Fibiger H.C. Lack of tolerance to nicotine-induced dopamine release in the nucleus accumbens. Eur. J. Pharmacol. 168:1989;363-368.
51. Dani J.A., Heinemann S. Molecular and cellular aspects of nicotine abuse. Neuron. 16:1996;905-908.
52. Dawe S., Gerada C., Russell M.A., Gray J.A. Nicotine intake in smokers increases following a single dose of haloperidol. Psychopharmacology. 117:1995;110-115.
53. De la Garza R., Johanson C.E. The discriminative stimulus properties of cocaine in the rhesus monkey. Pharmacol. Biochem. Behav. 19:1983;145-148.
54. De la Garza R., Johanson C.E. Discriminative stimulus properties of cocaine in pigeons. Psychopharmacology. 85:1985;23-30.
55. 3: a new member of nicotinic acetylcholine receptor gene family is expressed in brain. J. Biol. Chem. 264:1989;6268-6272.
56. Dewey S.L., Brodie J.D., Gerasimov B.M., Horan B., Gardner E.L., Ashby C.R. A pharmacologic strategy for the treatment of nicotine addiction. Synapse. 31:1999;76-86.
57. Di Chiara G. In vivo brain dialysis of neurotransmitters. Trends Pharmacol. Sci. 11:1990;116-121.
58. Di Chiara G. The role of dopamine in drug abuse viewed from the perspective of its role in motivation. Drug Alcohol Depend. 38:1995;95-137.
59. Di Chiara G. A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use. J. Psychopharmacol. 12:1998;54-67.
60. Di Chiara G. Drug addiction as dopamine-dependent associative learning disorder. Eur. J. Pharmacol. 375:1999;13-30.
61. Di Chiara G. Behavioural pharmacology and neurobiology of nicotine reward and dependence. Clementi F., Fornasari D., Gotti C. Handbook Exp. Pharmacology. Vol. 144:2000;Springer, Heidelberg.
62. Di Chiara G., Acquas E., Tanda G., Cadoni C. Drugs of abuse: biochemical surrogates of specific aspects of natural reward? Biochem. Soc. Symp. 59:1993;65-81.
63. Di Chiara G., Acquas E., Tanda G. Ethanol a neurochemical surrogate of conventional reinforcers the dopamine-opioid link. Alcohol. 13:1996;13-17.
64. Di Chiara G., Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl. Acad. Sci. U. S. A. 85:1988;5274-5278.
65. Di Chiara G., Loddo P., Tanda G. Reciprocal changes in prefrontal and limbic dopamine responsiveness to aversive and rewarding stimuli after chronic mild stress: implications for the psychobiology of depression. Biol. Psychiatry. 46:1999;1624-1633.
66. Di Chiara G., Tanda G., Carboni E. Estimation of in vivo neurotransmitter release by brain microdialysis: the issue of validity. Behav. Pharmacol. 7:1996;640-657.
67. Di Ciano P., Blaha C.D., Phillips A.G. Conditioned changes in dopamine oxidation currents in the nucleus accumbens of rats by stimuli paired with self-administration or yoked-administration of D-amphetamine. Eur. J. Neurosci. 10:1998;1121-1127.
68. Dickinson A. Instrumental conditioning. Mackintosh N. Animal Learning and Cognition. 1994;45-79 Academic Press, San Diego.
69. Dickinson A., Balleine B. Motivational control of instrumental action. Curr. Dir. Psychol. Sci. 4:1995;162-167.
70. Dineley-Miller K., Patrick J. Gene transcripts for the nicotinic acetylcholine receptor subunit β4 are distributed in multiple areas of the rat central nervous system. Mol. Brain Res. 16:1992;339-344.
71. Falk J.L. The nature and determinants of adjunctive behavior. Physiol. Behav. 6:1971;577-588.
72. Fu Y., Matta S.G., Sharp B.M. Local alpha-bungarotoxin (α-BTX)-sensitive nicotinic receptors modulate nicotine-induced dopamine (DA) release in the nucleus accumbens (NACC). Soc. Neurosci. 25:1999;187.
73. Fu Y., Matta S.G., Sharp B.M. Local α-bungarotoxin-sensitive nicotinic receptors modulate hippocampal norepinephrine release by systemic nicotine. JPET. 289:1999;133-139.
74. Fudala P.J., Iwamoto E.T. Further studies on nicotine-induced conditioned place preference in the rat. Pharmacol. Biochem. Behav. 25:1986;1041-1049.
75. Fudala P.J., Teoh K.W., Iwamoto E.T. Pharmacologic characterization of nicotine-induced conditioned place preference. Pharmacol. Biochem. Behav. 22:1985;237-241.
76. Gasior M., Shoaib M., Yasar S., Jaszyna M., Goldberg S.R. Acquisition of nicotine discrimination and discriminative stimulus effects of nicotine in rats chronically exposed to caffeine. J. Pharmacol. Exp. Ther. 288:1999;1053-1073.
77. Gilbert R.M. Schedule-induced self-administration of drugs. Blackman D.E., Sanger D.J. Contemporary Research in Behavioral Pharmacology. 1978;Plenum, New York.
78. Goldner F., Dineley K., Patrick J. Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 dopaminergic neurons in the substantia nigra and ventral tegmental area. NeuroReport. 8:1997;2739-2742.
79. Gray T., Wise R.A. Effects of pimozide on lever-pressing behavior maintained on an intermittent reinforcement schedule. Pharmacol. Biochem. Behav. 12:1980;931-935.
80. Gray J.A., Young A.M., Joseph M.H. Dopamine's role. Science. 278:1997;1548-1549. [letter].
81. Heimer L., Zahm D.S., Churchill L., Kalivas P.W., Wohltman C. Specificity in the projection patterns of accumbal core and shell in the rat. Neuroscience. 41:1991;89-125.
82. Hemby S.E., Co C., Koves T.R., Smith J.E., Dworkin S.I. Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat. Psychopharmacology. 133:1997;7-16.
83. Henningfield J.E., Goldberg S.R. Control of behavior by intravenous nicotine injections in human subjects. Pharmacol. Biochem. Behav. 19:1983;1021-1026.
84. Henningfield J.E., Goldberg S.R. Nicotine as a reinforcer in human subjects and laboratory animals. Pharmacol. Biochem. Behav. 19(6):1983;989-992.
85. Hernandez L., Hoebel B.G. Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. Life Sci. 42:1988;1705-1712.
86. Hildebrand B.E., Nomikos G.G., Hertel P., Schilstrom B., Svensson T.H. Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Brain Res. 779:1997;214-225.
87. Hill J.A. Jr., Zoli M., Bourgeois J.P., Changeux J.P. Immunocytochemical localization of a neuronal nicotinic receptor: the β2 subunit. J. Neurosci. 13:1993;1551-1568.
88. Hitchcott P.K., Bonardi C.M.T., Phillips G.D. Enhanced stimulus-reward learning by intra-amygdala administration of a D3 dopamine receptor agonist. Psychopharmacology. 133:1997;240-248.
89. Hitchcott P.K., Harmer C.J., Phillips G.D. Enhanced acquisition of discriminative approach following intra-amygdala D-amphetamine. Psychopharmacology. 132:1997;237-246.
90. Horan B., Smith M., Gardner E.L., Lepore M., Ashby C.R. Jr. (-)-Nicotine produces conditioned place preference in Lewis, but not Fischer 344 rats. Synapse. 26:1997;93-94.
91. Horvitz J.C., Ettenberg A. Conditioned incentive properties of a food-paired conditioned stimulus remain intact during dopamine receptor blockade. Behav. Neurosci. 105:1991;536-541.
92. Huston-Lyons D., Kornetsky C. Effects of nicotine on the threshold for rewarding brain stimulation in rats. Pharmacol. Biochem. Behav. 41:1992;755-759.
93. Huston-Lyons D., Sarkar M., Kornetsky C. Nicotine and brain-stimulation reward: interactions with morphine, amphetamine and pimozide. Pharmacol. Biochem. Behav. 46:1993;453-457.
94. Imperato A., Mulas A., Di Chiara G. Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats. Eur. J. Pharmacol. 132:1986;337-338.
95. Ivanova S., Greenshaw A.J. Nicotine-induced decreases in VTA electrical self-stimulation thresholds: blockade by haloperidol and mecamylamine but not scopolamine or ondansetron. Psychopharmacology. 134:1997;187-192.
96. 3H]dopamine release in rat striatum. J. Neurochem. 56:1991;603-610.
97. Krivanek J.A., McGaugh J.L. Facilitating effects of pre- and posttrial amphetamine administration on discrimination learning in mice. Agents Actions. 1:1969;36-42.
98. Ksir C., Mellor G., Hart C., Gerhardt G.A. Nicotine enhances dopamine clearance in C rat nucleus accumbens. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 19:1995;151-156.
99. Jorenby D.E., Steinpreis R.E., Sherman J.E., Baker T.B. Aversion instead of preference learning indicated by nicotine place conditioning in rats. Psychopharmacology. 101:1990;533-538.
100. Joseph M.H., Peters S.L., Gray J.A. Nicotine blocks latent inhibition in rats: evidence for a critical role of increased functional activity of dopamine in the mesolimbic system at conditioning rather than pre-exposure. Psychopharmacology. 110:1993;187-192.
101. Killcross A.S., Dickinson A., Robbins T.W. Amphetamine-induced disruptions of latent inhibition are reinforcer mediated: implications for animal models of schizoohrenic attentional dysfunction. Psychopharmacology. 115:1994;185-195.
102. Killcross A.S., Dickinson A., Robbins T.W. Effects of the neuroleptic α-flupenthixol on latent inhibition in aversively and appetitively motivated paradigms: evidence for dopamine-reinforcer interactions. Psychopharmacology. 115:1994;196-205.
103. Leikola-Pelho T., Jackson D.M. Preferential stimulation of locomotor activity by ventral tegmental microinjections of (-)nicotine. Pharmacol. Toxicol. 70:1992;50-52.
104. LeNovere N., Zoli M., Changeux J.P. Neuronal nicotinic receptors alpha 6 subunit mRNA is selectively concentrated in cathecolaminergic nuclei of the rat brain. Eur. J. Neurosci. 8:1996;2428-2439.
105. Louis M., Clarke P.B. Effect of ventral tegmental 6-hydroxydopamine lesions on the locomotor stimulant action of nicotine in rats. Neuropharmacology. 37:1998;1503-1513.
106. Maisonneuve I.M., Mann G.L., Deibel C.R. Ibogaine and the dopaminergic response to nicotine. Psychopharmacology. 129:1997;249-256.
107. Mansbach R.S., Rovetti C.C., Freedland C.S. The role of monoamine neurotransmitter systems in the nicotine discriminative stimulus. Drug Alcohol Depend. 52:1998;125-134.
108. Marks M.J., Campbell S.M., Romm E., Collins A.C. Genotype influences the development of tolerance to nicotine in the mouse. J. Pharmacol. Exp. Ther. 259:1991;392-402.
109. McEvoy J.P., Freudenreich O., Levin E.D., Rose J.E. Haloperidol increases smoking in patients with schizophrenia. Psychopharmacology. 119:1995;124-126.
110. McFarland K., Ettenberg A. Haloperidol differentially affects reinforcement and motivational processess in rats running an alley for intravenous heroin. Psychopharmacology. 122:1995;346-350.
111. Mereu G., Yoon K.-W.P., Boi V., Gessa G.L., Naes L., Westfall T.C. Preferential stimulation of ventral tegmental area dopaminergic neurons by nicotine. Eur. J. Pharmacol. 141:1987;395-399.
112. Museo E., Wise R.A. Microinjection of a nicotinic agonist into dopamine terminal fields: effects on locomotion. Pharmacol. Biochem. Behav. 37:1990;113-116.
113. Museo E., Wise R.A. Locomotion induced by ventral tegmental microinjections of a nicotinic agonist. Pharmacol. Biochem. Behav. 37:1990;735-737.
114. Museo E., Wise R.A. Cytisine-induced behavioral activation: delineation of neuroanatomical locus of action. Brain Res. 670:1995;257-263.
115. Neisewander J.L., O'Dell L.E., Ly M.A., Tran-Nguyen T.L., Edward Castañeda M.A., Fuchs R.A. Dopamine overflow in the nucleus accumbens during extinction and reinstatement of cocaine. Neuropsychopharmacology. 15:1996;506-514.
116. Nisell M., Marcus M., Nomikos G.G., Svensson T.H. Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens. J. Neural. Transm. 104:1997;1-10.
117. Nisell M., Nomikos G.G., Chergui K., Grillner P., Svensson T.H. Chronic nicotine enhances basal and nicotine-induced Fos immunoreactivity preferentially in the medial prefrontal cortex of the rat. Neuropsychopharmacology. 17:1997;151-161.
118. Nisell M., Nomikos G.G., Hertel P., Panagis G., Svensson T.H. Condition-independent sensitization of locomotor stimulation and mesocortical dopamine release following chronic nicotine treatment in the rat. Synapse. 22:1996;369-381.
119. Nisell M., Nomikos G.G., Svensson T.H. Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release. Pharmacol. Toxicol. 75:1994;348-352.
120. Nisell M., Nomikos G.G., Svensson T.H. Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area. Synapse. 16:1994;36-44.
121. O'Brien C.P. Drug addiction and drug abuse. Goodman L.S., Gilman A. The Pharmacological Basis of Therapeutics. 1996;Mc Graw Hill, New York.
122. Olale F., Gerzanich V., Kuryatov A., Wang F., Lindstrom J. Chronic nicotine exposure differentially affects the function of human α3, α4, and α7 neuronal nicotinic receptor subtypes. J. Pharmacol. Exp. Ther. 283:1997;675-683.
123. 2 dopamine receptors in mediating nicotine-induced hyperactivity in rats. Psychopharmacology. 104:1991;343-350.
124. Packard M.G., Cahill L., McGaugh J.L. Amygdala modulation of hippocampal-dependent and caudate nucleus-dependent memory processes. PNAS. 91:1994;8477-8481.
125. Packard M.G., White N.M. Dissociation of hippocampal and caudate nucleus memory systems by post-training intracerebral injection of dopamine agonists. Behav. Neurosci. 105:1991;295-306.
126. Palkovits M. Dopamine Levels of Individual Brain Regions: Biochemical Aspects of DA Distribution in the Central Nervous System. 1979;343-356 Academic Press, London.
127. Panagis G., Nisell M., Nomikos G.G., Chergui K., Svensson T.H. Nicotine injections into the ventral tegmental area increase locomotion and Fos-like immunostaining in the nucleus accumbens of the rat. Brain Res. 730:1996;133-142.
128. Parker L.A. Place conditioning in a three- or four-choice apparatus: role of stimulus novelty in drug-induced place conditioning. Behav. Neurosci. 106:1992;294-306.
129. Perkins K.A., DiMarco A., Grobe J.E., Scierka A., Stiller R.L. Nicotine discrimination in male and female smokers. Psychopharmacology. 116(4):1994;407-413.
130. Perkins K.A., Epstein L.H., Grobe J., Fonte C. Tobacco abstinence, smoking cues, and the reinforcing value of smoking. Pharmacol. Biochem. Behav. 47:1994;107-112.
131. Perkins K.A., Grobe J.E., Fonte C., Goettler J., Caggiula A.R., Reynolds W.A., Stiller R.L., Scierka A., Jacob R.G. Chronic and acute tolerance to subjective, behavioral and cardiovascular effects of nicotine in humans. J. Pharmacol. Exp. Ther. 270(2):1994;628-638.
132. Perkins K.A., Sexton J.E., Reynolds W.A., Grobe J.E., Fonte C., Stiller R.L. Comparison of acute subjective and heart rate effects of nicotine intake via tobacco smoking vs. nasal spray. Pharmacol. Biochem. Behav. 47:1994;295-299.
133. Perkins K.A., Sexton J.E., Stiller R.L., Fonte C., Di Marco A., Goettler J., Scierka A. Subjective and cardiovascular responses to nicotine combined with caffeine during rest and casual activity. Psychopharmacology. 113:1994;438-444.
134. Petitt H.O., Ettenberg A., Bloom F.E., Koob G.F. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology. 84:1984;167-173.
135. Petitt H.O., Justice J.B. Effect of dose on cocaine self-administration behavior and dopamine levels in the nucleus accumbens. Brain Res. 539:1991;94-102.
136. Petitt H.O., Justice J.B. Jr. Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis. Pharmacol. Biochem. Behav. 34:1989;899-904.
137. Phillips A.G., Fibiger H.C. Decreased resistance to extinction after haloperidol: implications for the role of dopamine in reinforcement. Pharmacol. Biochem. Behav. 10:1979;751-761.
138. Picciotto M.R., Zoli M., Rimondini R., Lena C., Marubio L.M., Pich E.M., Fuxe K., Changeux J.P. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature. 391:1998;173-177.
139. Pidoplichko V.I., DeBiasi M., Williams J.T., Dani J.A. Nicotine activates and desensitizes midbrain dopamine neurons. Nature. 390:1997;401-404.
140. Ploeger G.E., Spruijt B.M., Cools A.R. Spatial localization in the Morris watermaze task in rats: acquisition is affected by intra-accumbens injections of the dopaminergic antagonist haloperidol. Behav. Neurosci. 108:1994;927-934.
141. Pontieri F.E., Tanda G., Di Chiara G. Intravenous cocaine, morphine and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proc. Natl. Acad. Sci. U. S. A. 92:1995;12304-12308.
142. Pontieri F.E., Tanda G., Orzi F., Di Chiara G. Effects of nicotine on the nucleus accumbens and similarities to those of addictive drugs. Nature. 382:1996;255-257.
143. Preston K.L., Bigelow G.E. Subjective and discriminative effects of drugs. Behav. Pharmacol. 2:1991;293-313.
144. Radhakishun F.S., van Ree J.M., Westerink B.H.C. Scheduled eating increases dopamine release in the nucleus accumbens of food deprived rats as assessed with on-line brain dialysis. Neurosci. Lett. 85:1988;351-356.
145. Raiteri M., Del Carmine R., Bertollini A., Levi G. Effects of sympathomimetic amines on the synaptosomal transport of noradrenaline, dopamine and 5-hydroxytryptamine. Eur. J. Pharmacol. 41:1977;133-143.
146. Reavill C., Stolerman I.P. Interaction of nicotine with dopaminergic mechanisms assessed through drug discrimination and rotational behaviour in rats. J. Psychopharmacol. 1:1987;264-273.
147. Reavill C., Stolerman I.P. Locomotor activity in rats after administration of nicotinic agonists intracerebrally. Br. J. Pharmacol. 99:1990;273-278.
148. Reid M.S., Ho L.B., Berger S.P. Effects of environmental conditioning on the development of nicotine sensitization: behavioral and neurochemical analysis. Psychopharmacology. 126(4):1996;301-310.
149. Robbins T.W. The potentiation of conditioned reinforcement by psychomotor stimulant drugs: DA test of Hill's hypothesis. Psychopharmacology. 45:1975;103-114.
150. Robbins T.W., Koob G.F. Selective disruption of displacement behaviour by lesions of the mesolimbic dopamine system. Nature. 285:1980;409-412.
151. Robinson T.E., Berridge K.C. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res. Rev. 18:1993;247-291.
152. Rose J.E., Corrigall W.A. Nicotine self-administration in animals and humans: similarities and differences. Psychopharmacology. 130(1):1997;28-40.
153. Rosecrans J.A. Nicotine as a discriminative stimulus: a neurobiobehavioral approach to studying central cholinergic mechanisms. J. Subst. Abuse Treat. 1:1989;287-300.
154. Russell M.A.H. Nicotine intake and its control over smoking. Wonnacott S., Russell M.A.H., Stolerman I.P. Nicotine Psychopharmacology: Molecular, Cellular, and Behavioural Aspects. 1990;374-427 Oxford Univ. Press, New York.
155. Salamone J.D. Complex motor and sensorimotor function of striatal and accumbens dopamine: involvement in instrumental behavior processes. Psychopharmacology. 107:1992;160-174.
156. Salamone J.D. The involvement of nucleus accumbens dopamine in appetitive and aversive motivation. Behav. Brain Res. 61:1994;117-133.
157. Sanger D.J. Drug taking as adjunctive behavior. Goldberg S.A., Stolermans J. Behavioural Analysis of Drug Dependence. 1986;123-160 Academic Press, New York.
158. Saulskaya N., Marsden C.A. Conditional dopamine release: dependence upon N-methyl-D-aspartate receptors. Neuroscience. 67:1995;57-63.
159. Schechter M.D., Meehan S.M. Further evidence for the mechanisms that may mediate nicotine discrimination. Pharmacol. Biochem. Behav. 41:1992;807-812.
160. Schechter M.D., Meehan S.M. Dopaminergic mediation of the stimulant generalization of nicotine. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 17:1993;835-845.
161. Schilström B., Nomikos G.G., Nisell M., Hertel P., Svensson T.H. N-methyl-D-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens. Neuroscience. 82:1998;781-789.
162. Schilström B., Svensson H.M., Svensson T.H., Nomikos G.G. Nicotine and food induced dopamine release in the nucleus accumbens of the rat: putative role of α7 nicotinic receptors in the ventral tegmental area. Neuroscience. 85:1998;1005-1009.
163. Schultz W., Apicella P., Ljungberg T. Responses of monkey dopamine neurons to reward and conditioned stimuli during successive steps of learning a delayed response task. J. Neurosci. 13:1993;900-913.
164. Schultz W., Dayan P., Montague P.R. A neural substrate of prediction and reward. Science. 275:1997;1593-1599.
165. Setlow B., McGaugh J.L. Sulpiride infused into the nucleus accumbens post-training impairs memory of spatial water maze training. Behav. Neurosci. 112:1998;603-610.
166. Singer G., Oei T.P., Wallace M. Schedule-induced self-injection of drugs. Neurosci. Biobehav. Rev. 6:1982;77-83.
167. Singer G., Wallace M., Hall R. Effects of dopaminergic nucleus accumbens lesions on the acquisition of schedule induced self injection of nicotine in the rat. Pharmacol. Biochem. Behav. 17:1982;579-581.
168. Sorenson E.M., Shiroyama T., Kitai S.T. Postsynaptic nicotinic receptors on dopaminergic neurons in the substantia nigra pars compacta of the rat. Neuroscience. 87:1998;659-673.
169. Stolerman I.P. Psychopharmacology of nicotine: stimulus effects and receptor mechanisms. Iversen L.L., Iversen S.D., Snyder S.H. Handbook of Psychopharmacology. Vol. 19:1987;421-465 Plenum, New York.
170. Stolerman I.P. Drugs of abuse: behavioural principles, methods and terms. Trends Pharmacol. Sci. 13:1992;170-176.
171. Stolerman I.P. Interspecies consistency in the behavioural pharmacology of nicotine dependence. Behav. Pharmacol. 10:1999;559-580.
172. Stolerman I.P., Garcha H.S., Pratt J.A., Kumar R. Role of training dose in discrimination of nicotine and related compounds by rats. Psychopharmacology. 84(3):1984;413-419.
173. Svensson T.H., Mathe J.M., Nomikos G.G., Schilstrom B. Role of excitatory amino acids in the ventral tegmental area for central actions of non-competitive NMDA-receptor antagonists and nicotine. Amino Acids. 14:1998;51-56.
174. Swanson L.W., Simmons D.M., Whiting P.J., Lindstrom J. Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system. J. Neurosci. 7:1987;3334-3342.
175. Tanda G., Carboni E., Frau R., Di Chiara G. Increase of extracellular dopamine in the prefrontal cortex: a trait of drugs with antidepressant potential? Psychopharmacology. 115:1994;285-288.
176. 1 opioid link in the rat ventral tegmentum shared by palatable food (Fonzies) and non-psychostimulant drugs of abuse. Eur. J. Neurosci. 10:1998;1179-1187.
177. 1 opioid receptor mechanism. Science. 276:1997;2048-2050.
178. Tanda G., Pontieri F.E., Frau R., Di Chiara G. Contribution of noradrenaline carrier to the increase of extracellular dopamine in the rat prefrontal cortex by amphetamine and cocaine. Eur. J. Neurosci. 9:1997;2077-2085.
179. Taylor J.R., Robbins T.W. 6-Hydroxydopamine lesions of the nucleus accumbens, but not of the caudate nucleus, attenuate enhanced responding with reward-related stimuli produced by intra-accumbens D-amphetamine. Psychopharmacology. 90:1986;390-397.
180. Thornton J.C., Dawe S., Lee C., Capstick C., Corr P.J., Cotter P., Frangou S., Gray N.S., Russell M.A.H., Gray J.A. Effects of nicotine and amphetamine on latent inhibition in human subjects. Psychopharmacology. 127:1996;164-173.
181. Tiffany S.T. A cognitive model of drug urges and drug use behavior: role of automatic and nonautomatic processess. Psychol. Rev. 97:1990;147-168.
182. Vezina P., Hervé D., Glowinski J., Tassin J.P. Injections of 6-hydroxydopamine into the ventral tegmental area destroy mesolimbic dopamine neurons but spare the locomotor activating effects of nicotine in the rat. Neurosci. Lett. 168:1994;111-114.
183. Wada E., McKinnon D., Heinemann S., Patrick J., Swanson L.W. The distribution of mRNA encoded by a new member of the neuronal nicotinic acetylcholine receptor gene family (α5) in the rat central nervous system. Brain Res. 526:1990;45-53.
184. Wada E., Wada K., Boulter J., Deneris E., Heineman S., Patrick J., Swanson L.W. Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat. J. Comp. Neurol. 284:1989;314-335.
185. Walter S., Kuschinsky K. Conditioning of nicotine effects on motility and behaviour in rats. Naunyn-Schmiedeberg's Arch. Pharmacol. 339(1-2):1989;208-213.
186. Weiner I. Neural substrates of latent inhibition: the switching model. Psychol. Bull. 10:1990;442-461.
187. White N.M., Viaud M.D. Localized intracaudate dopamine D2 receptor activation during the post-training period improves memory for visual or olfactory conditioned emotional responses in the rat. Behav. Neural Biol. 55:1991;255-269.
188. Wise R.A. Neuroleptics and operant behavior: the anhedonia hypothesis. Behav. Brain Sci. 5:1982;39-87.
189. Wise R.A., Leone P., Rivest P., Leeb K. Elevations of nucleus accumbeans dopamine and DOPAC levels during intravenous heroin self-administration. Synapse. 21:1995;140-148.
190. Wise R.A., Newton P., Leeb K., Burnette B., Pocock D., Justice J.B. Jr. Fluctuations in nucleus accumbens dopamine concentration during intravenous cocaine self-administration in rats. Psychopharmacology. 120:1995;10-20.
191. Wolterink G., Phillips G., Cador M., Donselaar-Wolterink I., Robbins T.W., Everitt B.J. Relative roles of ventral striatal D1 and D2 dopamine receptors in responding with conditioned reinforcement. Psychopharmacology. 110:1993;355-364.
192. Young A.M.J., Joseph M.H., Gray J.A. Latent inhibition of conditioned dopamine release in rat nucleus accumbens. Neuroscience. 54:1993;5-9.