The hedgehog knows many tricks

Current Drug Targets

Volumn 12, Issue 14, 2011, Pages 2091-2095

  Weiss, Glen J ^a,b   Mita, Alain C ^c   von Hoff, Daniel D ^a,b  

^a Scottsdale Clinical Research Institute   (United States)

^b TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^c CTRC Institute for Drug Development   (United States)

Author keywords

Autocrine; Cancer; Hedgehog pathway; Mutation; Paracrine; Signaling; Treatment

Indexed keywords

ANGIOPOIETIN; ANTINEOPLASTIC AGENT; BEVACIZUMAB; BMS 833923; CISPLATIN; CYCLOPAMINE; ERISMODEGIB; ERLOTINIB; ETOPOSIDE; IPI 926; LIGAND; PF 04449913; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG; VASCULOTROPIN; VISMODEGIB; XL 139;

ADVANCED CANCER; ANOREXIA; AUTOCRINE EFFECT; BACKACHE; BASAL CELL CARCINOMA; CANCER REGRESSION; CANCER STEM CELL; CELL PROLIFERATION; COLORECTAL CANCER; CONGENITAL MALFORMATION; DEHYDRATION; DYSGEUSIA; DYSPEPSIA; DYSPNEA; FATIGUE; HEART ATRIUM FIBRILLATION; HUMAN; HYPOCALCEMIA; HYPONATREMIA; KERATITIS; LUNG SMALL CELL CANCER; LYMPHOCYTOPENIA; MEDULLOBLASTOMA; METASTASIS; MUSCLE SPASM; OVARY CANCER; PANCREAS CANCER; PARACRINE SIGNALING; REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; UPREGULATION; URINARY TRACT INFECTION; WEIGHT REDUCTION;

ANIMALS; CLINICAL TRIALS AS TOPIC; HEDGEHOG PROTEINS; HUMANS; NEOPLASMS; NEOPLASTIC STEM CELLS; RESEARCH DESIGN; SIGNAL TRANSDUCTION;

EID: 84855841150     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/138945011798829429     Document Type: Review

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