Cells with dysfunctional telomeres are susceptible to reactive oxygen species hydrogen peroxide via generation of multichromosomal fusions and chromosomal fragments bearing telomeres

Biochemical and Biophysical Research Communications

Volumn 417, Issue 1, 2012, Pages 204-210

  Woo, Seon Rang ^a,e   Park, Jeong Eun ^a   Juhn, Kyoung Mi ^a   Ju, Yeun Jin ^a   Jeong, Jaemin ^a   Kang, Chang Mo ^a   Yun, Hyun Jin ^a   Yun, Mi Yong ^a   Shin, Hyun Jin ^a   Joo, Hyun Yoo ^a   Park, Eun Ran ^a   Park, In Chul ^a   Hong, Sung Hee ^a   Hwang, Sang Gu ^a   Kim, Haekwon ^b   Cho, Myung Haing ^c   Kim, Sang Hoon ^d   Park, Gil Hong ^e   Lee, Kee Ho ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b Seoul Women University   (South Korea)

^c Seoul National University   (South Korea)

^d Kyung Hee University   (South Korea)

^e Korea University College of Medicine   (South Korea)

Author keywords

Chromosomal fragment; H 2O 2; Multichromosomal fusion; Telomerase; Telomere

Indexed keywords

ACETYLCYSTEINE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DIVISION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CHROMOSOME ABERRATION; CHROMOSOME DISORDER; CONTROLLED STUDY; FUSION GENE; GENOMIC FRAGMENT; METAPHASE CHROMOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE; TELOMERE;

ACETYLCYSTEINE; ANIMALS; CELL DIVISION; CHROMOSOME ABERRATIONS; G2 PHASE; HYDROGEN PEROXIDE; MICE; MICE, MUTANT STRAINS; RNA; TELOMERASE; TELOMERE;

EID: 84855806886     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.11.086     Document Type: Article

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