Liver glucokinase A456V induces potent hypoglycemia without dyslipidemia through a paradoxical induction of the catalytic subunit of glucose-6- phosphatase

International Journal of Endocrinology

Volumn 2011, Issue , 2011, Pages

  Vidal Alabró, Anna ^a   Gómez Valadés, Alícia G ^a   Méndez Lucas, Andrés ^a   Llorens, Jordi ^a   Bartrons, Ramon ^a   Bermúdez, Jordi ^a   Perales, Jose C ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; FRUCTOSE 2,6 BISPHOSPHATE; GLUCOKINASE; GLUCOKINASE REGULATOR PROTEIN; GLUCOSE; GLUCOSE 6 PHOSPHATASE; MESSENGER RNA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; DYSLIPIDEMIA; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME DEREGULATION; ENZYME INDUCTION; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYME REGULATION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE UTILIZATION; GLYCOGEN ANALYSIS; HOMEOSTASIS; HYPOGLYCEMIA; IN VIVO STUDY; LIPID HOMEOSTASIS; LIVER CELL; LIVER CYTOSOL; LIVER METABOLISM; MALE; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; UPREGULATION; WILD TYPE;

EID: 84855606404     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2011/707928     Document Type: Article

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