Stable extracellular RNA fragments of mycobacterium tuberculosis induce early apoptosis in human monocytes via a Caspase-8 dependent mechanism

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Obregón Henao, Andrés ^a,b   Duque Correa, María A ^a   Rojas, Mauricio ^a   García, Luis F ^a   Brennan, Patrick J ^b   Ortiz, Blanca L ^a   Belisle, John T ^b  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; INTERLEUKIN 10; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; RIBOSOME RNA; TRANSFER RNA; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL RNA; CASP8 PROTEIN, HUMAN; CONCANAVALIN A; SEPHAROSE;

APOPTOSIS; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CELL DAMAGE; CELL MEMBRANE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE FUNCTION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN SECRETION; AFFINITY CHROMATOGRAPHY; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; EXTRACELLULAR SPACE; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; MICROBIOLOGY; TUBERCULOSIS;

BACILLI (CLASS); BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

APOPTOSIS; CASPASE 8; CHROMATOGRAPHY, AFFINITY; CONCANAVALIN A; EXTRACELLULAR SPACE; HUMANS; KINETICS; MONOCYTES; MYCOBACTERIUM TUBERCULOSIS; RNA, BACTERIAL; SEPHAROSE; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84855514952     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029970     Document Type: Article

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