A TNF- and c-Cbl-dependent FLIPS-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis

Nature Immunology

Volumn 10, Issue 8, 2009, Pages 918-926

  Kundu, Manikuntala ^a   Pathak, Sushil Kumar ^a   Kumawat, Kuldeep ^a   Basu, Sanchita ^a   Chatterjee, Gargi ^a   Pathak, Shresh ^a   Noguchi, Takuya ^b   Takeda, Kohsuke ^b   Ichijo, Hidenori ^b   Thien, Christine B F ^c   Langdon, Wallace Y ^c   Basu, Joyoti ^a  

^a BOSE INSTITUTE   (India)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE 8; CBL PROTEIN; FLICE INHIBITORY PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; SERINE; TUMOR NECROSIS FACTOR; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CELL LINE; CELL PROLIFERATION; HUMANS; MACROPHAGES; MAP KINASE KINASE KINASE 5; MICE; MICE, KNOCKOUT; MYCOBACTERIUM TUBERCULOSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-ABL; PROTO-ONCOGENE PROTEINS C-CBL; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITINATION;

EID: 67651163398     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1754     Document Type: Article

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