Computational design of the sequence and structure of a protein-binding peptide

Journal of the American Chemical Society

Volumn 133, Issue 12, 2011, Pages 4190-4192

  Sammond, Deanne W ^a,b   Bosch, Dustin E ^a   Butterfoss, Glenn L ^a,c   Purbeck, Carrie ^a   MacHius, Mischa ^a   Siderovski, David P ^a   Kuhlman, Brian ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL DESIGN; COMPUTATIONAL MODEL; COMPUTATIONAL STRATEGY; DE NOVO DESIGN; PROTEIN-BINDING; ROOT-MEAN SQUARE DEVIATION; SEQUENCE OPTIMIZATION; TERMINAL PORTIONS; X RAY CRYSTAL STRUCTURES;

CONFORMATIONS; PEPTIDES; STRUCTURAL DESIGN; STRUCTURAL OPTIMIZATION;

CRYSTAL STRUCTURE;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; HYDROGEN BOND; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PEPTIDES; PROTEIN CONFORMATION;

EID: 79953058640     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja110296z     Document Type: Article

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