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Volumn 107, Issue 1, 2012, Pages 172-183

Ultrasound molecular imaging of arterial thrombi with novel microbubbles modified by cyclic RGD in vitro and in vivo

Author keywords

Arterial thrombus; Cyclic RGD; Microbubbles; Ultrasound molecular imaging

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; FIBRINOGEN RECEPTOR;

EID: 84855311082     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-11-0701     Document Type: Article
Times cited : (37)

References (45)
  • 1
    • 22244460811 scopus 로고    scopus 로고
    • Hyperhomocysteinemia, thrombosis and vascular biology. Cellular and molecular biology (Noisy-le-Grand
    • Ebbesen LS. Hyperhomocysteinemia, thrombosis and vascular biology. Cellular and molecular biology (Noisy-le-Grand, France) 2004; 50: 917-930.
    • (2004) France) , vol.50 , pp. 917-930
    • Ebbesen, L.S.1
  • 2
    • 33846449133 scopus 로고    scopus 로고
    • An experimentally antithrombotic strawberry variety is also effective in humans
    • Naemura A, Ohira H, Ikeda M, et al. An experimentally antithrombotic strawberry variety is also effective in humans. Pathophysiol Haemost Thromb 2006; 35: 398-404.
    • (2006) Pathophysiol Haemost Thromb , vol.35 , pp. 398-404
    • Naemura, A.1    Ohira, H.2    Ikeda, M.3
  • 3
    • 0033046853 scopus 로고    scopus 로고
    • Pathogenesis of atherosclerosis in diabetes and hypertension
    • Shantaram V. Pathogenesis of atherosclerosis in diabetes and hypertension. Clin Exp Hypertens 1999; 21: 69-77.
    • (1999) Clin Exp Hypertens , vol.21 , pp. 69-77
    • Shantaram, V.1
  • 4
    • 0037123152 scopus 로고    scopus 로고
    • In vivo noninvasive detection and age definition of arterial thrombus by MRI
    • Corti R, Osende JI, Fayad ZA, et al. In vivo noninvasive detection and age definition of arterial thrombus by MRI. J Am Coll Cardiol 2002; 39: 1366-1373.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1366-1373
    • Corti, R.1    Osende, J.I.2    Fayad, Z.A.3
  • 5
    • 68949160006 scopus 로고    scopus 로고
    • Cardiovascular molecular imaging: An overview
    • Saraste A, Nekolla SG, Schwaiger M. Cardiovascular molecular imaging: an overview. Cardiovasc Res 2009; 83: 643-652.
    • (2009) Cardiovasc Res , vol.83 , pp. 643-652
    • Saraste, A.1    Nekolla, S.G.2    Schwaiger, M.3
  • 6
    • 77952892389 scopus 로고    scopus 로고
    • Molecular sonography with targeted microbubbles: Current investigations and potential applications
    • Hwang M, Lyshchik A, Fleischer AC. Molecular sonography with targeted microbubbles: current investigations and potential applications. Ultrasound Quart 2010; 26: 75-82.
    • (2010) Ultrasound Quart , vol.26 , pp. 75-82
    • Hwang, M.1    Lyshchik, A.2    Fleischer, A.C.3
  • 7
    • 34247573436 scopus 로고    scopus 로고
    • Molecular imaging of human thrombus with novel abciximab immunobubbles and ultrasound
    • Alonso A, Della Martina A, Stroick M, et al. Molecular imaging of human thrombus with novel abciximab immunobubbles and ultrasound. Stroke 2007; 38: 1508-1514.
    • (2007) Stroke , vol.38 , pp. 1508-1514
    • Alonso, A.1    della Martina, A.2    Stroick, M.3
  • 8
    • 14044270687 scopus 로고    scopus 로고
    • Virchow's triad revisited: Abnormal flow
    • Lowe GD. Virchow's triad revisited: abnormal flow. Pathophysiol Haemost Thromb 2003; 33: 455-457.
    • (2003) Pathophysiol Haemost Thromb , vol.33 , pp. 455-457
    • Lowe, G.D.1
  • 9
    • 34247402058 scopus 로고    scopus 로고
    • Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongation
    • Stoll P, Bassler N, Hagemeyer CE, et al. Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongation. Arterioscl Thromb Vasc Biol 2007; 27: 1206-1212.
    • (2007) Arterioscl Thromb Vasc Biol , vol.27 , pp. 1206-1212
    • Stoll, P.1    Bassler, N.2    Hagemeyer, C.E.3
  • 10
    • 0034742631 scopus 로고    scopus 로고
    • AlphaIIbbeta3 and its antagonism at the new millennium
    • Plow EF, Cierniewski CS, Xiao Z, et al. AlphaIIbbeta3 and its antagonism at the new millennium. Thromb Haemost 2001; 86: 34-40.
    • (2001) Thromb Haemost , vol.86 , pp. 34-40
    • Plow, E.F.1    Cierniewski, C.S.2    Xiao, Z.3
  • 11
    • 43749122810 scopus 로고    scopus 로고
    • Allosteric regulation of alpha(IIb)beta(3) by beta(3) 95-105
    • Haas TA. Allosteric regulation of alpha(IIb)beta(3) by beta(3) 95-105. Thromb Haemost 2008; 99: 701-710.
    • (2008) Thromb Haemost , vol.99 , pp. 701-710
    • Haas, T.A.1
  • 12
    • 0032543535 scopus 로고    scopus 로고
    • In vitro studies of a new thrombusspecific ultrasound contrast agent
    • Unger EC, McCreery TP, Sweitzer RH, et al. In vitro studies of a new thrombusspecific ultrasound contrast agent. Am J Cardiol 1998; 81: 58G-61G.
    • (1998) Am J Cardiol , vol.81
    • Unger, E.C.1    McCreery, T.P.2    Sweitzer, R.H.3
  • 13
    • 0032764702 scopus 로고    scopus 로고
    • Enhanced visualization of intravascular and left atrial appendage thrombus with the use of a thrombus-targeting ultrasonographic contrast agent (MRX-408A1): In vivo experimental echocardiographic studies
    • Takeuchi M, Ogunyankin K, Pandian NG, et al. Enhanced visualization of intravascular and left atrial appendage thrombus with the use of a thrombus-targeting ultrasonographic contrast agent (MRX-408A1): In vivo experimental echocardiographic studies. J Am Soc Echocardiogr 1999; 12: 1015-1021.
    • (1999) J Am Soc Echocardiogr , vol.12 , pp. 1015-1021
    • Takeuchi, M.1    Ogunyankin, K.2    Pandian, N.G.3
  • 14
    • 0036830189 scopus 로고    scopus 로고
    • Targeted-microbubble binding selectively to GPIIb IIIa receptors of platelet thrombi
    • Schumann PA, Christiansen JP, Quigley RM, et al. Targeted-microbubble binding selectively to GPIIb IIIa receptors of platelet thrombi. Invest Radiol 2002; 37: 587-593.
    • (2002) Invest Radiol , vol.37 , pp. 587-593
    • Schumann, P.A.1    Christiansen, J.P.2    Quigley, R.M.3
  • 15
    • 0026799510 scopus 로고
    • Synergistic antithrombotic properties of G4120, a RGD-containing synthetic peptide, and argatroban, a synthetic thrombin inhibitor, in a hamster femoral vein platelet-rich thrombosis model
    • Imura Y, Stassen JM, Vreys I, et al. Synergistic antithrombotic properties of G4120, a RGD-containing synthetic peptide, and argatroban, a synthetic thrombin inhibitor, in a hamster femoral vein platelet-rich thrombosis model. Thromb Haemost 1992; 68: 336-340.
    • (1992) Thromb Haemost , vol.68 , pp. 336-340
    • Imura, Y.1    Stassen, J.M.2    Vreys, I.3
  • 17
    • 0033030771 scopus 로고    scopus 로고
    • The effect of conformation on the solution stability of linear vs. cyclic RGD peptides
    • Bogdanowich-Knipp SJ, Jois DS, Siahaan TJ. The effect of conformation on the solution stability of linear vs. cyclic RGD peptides. J Pept Res 1999; 53: 523-529.
    • (1999) J Pept Res , vol.53 , pp. 523-529
    • Bogdanowich-Knipp, S.J.1    Jois, D.S.2    Siahaan, T.J.3
  • 18
    • 0032979942 scopus 로고    scopus 로고
    • Molecular dynamics study of disulfide bond influence on properties of an RGD peptide
    • Wang Y, Goh SY, Kuczera K. Molecular dynamics study of disulfide bond influence on properties of an RGD peptide. J Pept Res 1999; 53: 188-200.
    • (1999) J Pept Res , vol.53 , pp. 188-200
    • Wang, Y.1    Goh, S.Y.2    Kuczera, K.3
  • 19
    • 1542267780 scopus 로고    scopus 로고
    • Using model substrates to study the dependence of focal adhesion formation on the affinity of integrin-ligand complexes
    • Kato M, Mrksich M. Using model substrates to study the dependence of focal adhesion formation on the affinity of integrin-ligand complexes. Biochemistry 2004; 43: 2699-2707.
    • (2004) Biochemistry , vol.43 , pp. 2699-2707
    • Kato, M.1    Mrksich, M.2
  • 20
    • 35748942932 scopus 로고    scopus 로고
    • Development and application of peptide-based radiopharmaceuticals
    • Dijkgraaf I, Boerman OC, Oyen WJ, et al. Development and application of peptide-based radiopharmaceuticals. Anti-cancer Agents Med Chem 2007; 7: 543-551.
    • (2007) Anti-cancer Agents Med Chem , vol.7 , pp. 543-551
    • Dijkgraaf, I.1    Boerman, O.C.2    Oyen, W.J.3
  • 21
    • 33750420717 scopus 로고    scopus 로고
    • Radiolabeled multimeric cyclic RGD peptides as integrin alphavbeta3 targeted radiotracers for tumor imaging
    • Liu S. Radiolabeled multimeric cyclic RGD peptides as integrin alphavbeta3 targeted radiotracers for tumor imaging. Mol Pharmaceutics 2006; 3: 472-487.
    • (2006) Mol Pharmaceutics , vol.3 , pp. 472-487
    • Liu, S.1
  • 22
    • 72449156995 scopus 로고    scopus 로고
    • Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: Maximizing binding affinity via bivalency
    • Liu S. Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency. Bioconj Chem 2009; 20: 2199-2213.
    • (2009) Bioconj Chem , vol.20 , pp. 2199-2213
    • Liu, S.1
  • 23
    • 70449120916 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of (99m)Tc-DTPA-bis(His) as a potential probe for tumor imaging with SPECT
    • Sinha D, Shukla G, Chuttani K, et al. Synthesis and biological evaluation of (99m)Tc-DTPA-bis(His) as a potential probe for tumor imaging with SPECT. Cancer Biother Radiopharm 2009; 24: 615-620.
    • (2009) Cancer Biother Radiopharm , vol.24 , pp. 615-620
    • Sinha, D.1    Shukla, G.2    Chuttani, K.3
  • 24
    • 75649085996 scopus 로고    scopus 로고
    • Dendronized iron oxide nanoparticles as contrast agents for MRI
    • Basly B, Felder-Flesch D, Perriat P, et al. Dendronized iron oxide nanoparticles as contrast agents for MRI. Chemical Comm 2010; 46: 985-987.
    • (2010) Chemical Comm , vol.46 , pp. 985-987
    • Basly, B.1    Felder-Flesch, D.2    Perriat, P.3
  • 25
    • 12344323482 scopus 로고    scopus 로고
    • Ligand-carrying gas-filled microbubbles: Ultrasound contrast agents for targeted molecular imaging
    • Klibanov AL. Ligand-carrying gas-filled microbubbles: ultrasound contrast agents for targeted molecular imaging. Bioconj Chem 2005; 16: 9-17.
    • (2005) Bioconj Chem , vol.16 , pp. 9-17
    • Klibanov, A.L.1
  • 26
    • 77957253179 scopus 로고    scopus 로고
    • scVEGF microbubble ultrasound contrast agents: A novel probe for ultrasound molecular imaging of tumor angiogenesis
    • Anderson CR, Rychak JJ, Backer M, et al. scVEGF microbubble ultrasound contrast agents: a novel probe for ultrasound molecular imaging of tumor angiogenesis. Invest Radiol 2010; 45: 579-585.
    • (2010) Invest Radiol , vol.45 , pp. 579-585
    • Anderson, C.R.1    Rychak, J.J.2    Backer, M.3
  • 27
    • 80052048934 scopus 로고    scopus 로고
    • Integrin alphavbeta3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy
    • Xie H, Diagaradjane P, Deorukhkar AA, et al. Integrin alphavbeta3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy. Int J Nanomed 2011; 6: 259-269.
    • (2011) Int J Nanomed , vol.6 , pp. 259-269
    • Xie, H.1    Diagaradjane, P.2    Deorukhkar, A.A.3
  • 28
    • 2142758635 scopus 로고    scopus 로고
    • Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow
    • Takalkar AM, Klibanov AL, Rychak JJ, et al. Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow. J Control Release 2004; 96: 473-482.
    • (2004) J Control Release , vol.96 , pp. 473-482
    • Takalkar, A.M.1    Klibanov, A.L.2    Rychak, J.J.3
  • 29
    • 34948901570 scopus 로고    scopus 로고
    • Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow
    • Klibanov AL, Rychak JJ, Yang WC, et al. Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media Mol Imag 2006; 1: 259-266.
    • (2006) Contrast Media Mol Imag , vol.1 , pp. 259-266
    • Klibanov, A.L.1    Rychak, J.J.2    Yang, W.C.3
  • 30
    • 42349091473 scopus 로고    scopus 로고
    • Assessment of alphavbeta3 integrin expression after myocardial infarction by positron emission tomography
    • Higuchi T, Bengel FM, Seidl S, et al. Assessment of alphavbeta3 integrin expression after myocardial infarction by positron emission tomography. Cardiovasc Res 2008; 78: 395-403.
    • (2008) Cardiovasc Res , vol.78 , pp. 395-403
    • Higuchi, T.1    Bengel, F.M.2    Seidl, S.3
  • 31
    • 34848867912 scopus 로고    scopus 로고
    • Enhanced detection of thromboemboli with the use of targeted microbubbles
    • Martin MJ, Chung EM, Goodall AH, et al. Enhanced detection of thromboemboli with the use of targeted microbubbles. Stroke 2007; 38: 2726-2732.
    • (2007) Stroke , vol.38 , pp. 2726-2732
    • Martin, M.J.1    Chung, E.M.2    Goodall, A.H.3
  • 32
    • 1242330435 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of a (99m)Tc-labelled cyclic RGD peptide for imaging the alphavbeta3 expression
    • Haubner R, Bruchertseifer F, Bock M, et al. Synthesis and biological evaluation of a (99m)Tc-labelled cyclic RGD peptide for imaging the alphavbeta3 expression. Nuklearmed 2004; 43: 26-32.
    • (2004) Nuklearmed , vol.43 , pp. 26-32
    • Haubner, R.1    Bruchertseifer, F.2    Bock, M.3
  • 33
    • 33748922791 scopus 로고    scopus 로고
    • Cell adhesion molecules for targeted drug delivery
    • Dunehoo AL, Anderson M, Majumdar S, et al. Cell adhesion molecules for targeted drug delivery. J Pharmaceut Sci 2006; 95: 1856-1872.
    • (2006) J Pharmaceut Sci , vol.95 , pp. 1856-1872
    • Dunehoo, A.L.1    Anderson, M.2    Majumdar, S.3
  • 34
    • 2342439574 scopus 로고    scopus 로고
    • Radiolabeled tracers for imaging of tumor angiogenesis and evaluation of anti-angiogenic therapies
    • Haubner R, Wester HJ. Radiolabeled tracers for imaging of tumor angiogenesis and evaluation of anti-angiogenic therapies. Curr Pharmaceut Design 2004; 10: 1439-1455.
    • (2004) Curr Pharmaceut Design , vol.10 , pp. 1439-1455
    • Haubner, R.1    Wester, H.J.2
  • 35
    • 33746576145 scopus 로고    scopus 로고
    • Alphavbeta3-integrin imaging: A new approach to characterise angiogenesis?
    • Haubner R. Alphavbeta3-integrin imaging: a new approach to characterise angiogenesis? Eur J Nuclear Med Mol Imag 2006; 33 (Suppl 1): 54-63.
    • (2006) Eur J Nuclear Med Mol Imag , vol.33 , Issue.SUPPL. 1 , pp. 54-63
    • Haubner, R.1
  • 36
    • 77954866783 scopus 로고    scopus 로고
    • Liposomal Cu-64 Labeling Method Using Bifunctional Chelators: Poly(ethylene glycol) Spacer and Chelator Effects
    • Seo JW, Mahakian LM, Kheirolomoom A, et al. Liposomal Cu-64 Labeling Method Using Bifunctional Chelators: Poly(ethylene glycol) Spacer and Chelator Effects. Bioconjug Chem 2010; 21: 1206-1215.
    • (2010) Bioconjug Chem , vol.21 , pp. 1206-1215
    • Seo, J.W.1    Mahakian, L.M.2    Kheirolomoom, A.3
  • 37
    • 77951768789 scopus 로고    scopus 로고
    • Design of an optimized scaffold for affibody molecules
    • Feldwisch J, Tolmachev V, Lendel C, et al. Design of an optimized scaffold for affibody molecules. J Mol Biol 2010; 398: 232-247.
    • (2010) J Mol Biol , vol.398 , pp. 232-247
    • Feldwisch, J.1    Tolmachev, V.2    Lendel, C.3
  • 38
    • 77953545361 scopus 로고    scopus 로고
    • Tracking of antibody reduction fragments by capillary gel electrophoresis during the coupling to microparticles surface
    • Cherkaoui S, Bettinger T, Hauwel M, et al. Tracking of antibody reduction fragments by capillary gel electrophoresis during the coupling to microparticles surface. J Pharma Biomed Anal 2010; 53: 172-178.
    • (2010) J Pharma Biomed Anal , vol.53 , pp. 172-178
    • Cherkaoui, S.1    Bettinger, T.2    Hauwel, M.3
  • 39
    • 37249000281 scopus 로고    scopus 로고
    • Shear-induced disulfide bond formation regulates adhesion activity of von Willebrand factor
    • Choi H, Aboulfatova K, Pownall HJ, et al. Shear-induced disulfide bond formation regulates adhesion activity of von Willebrand factor. J Biol Chem 2007; 282: 35604-35611.
    • (2007) J Biol Chem , vol.282 , pp. 35604-35611
    • Choi, H.1    Aboulfatova, K.2    Pownall, H.J.3
  • 40
    • 45549090659 scopus 로고    scopus 로고
    • Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions
    • Li Y, Choi H, Zhou Z, et al. Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions. J Thromb Haemost 2008; 6: 1135-1143.
    • (2008) J Thromb Haemost , vol.6 , pp. 1135-1143
    • Li, Y.1    Choi, H.2    Zhou, Z.3
  • 41
    • 33846909478 scopus 로고    scopus 로고
    • Molecular imaging with targeted contrast ultrasound
    • Kaufmann BA, Lindner JR. Molecular imaging with targeted contrast ultrasound. Curr Opin Biotechnol 2007; 18: 11-16.
    • (2007) Curr Opin Biotechnol , vol.18 , pp. 11-16
    • Kaufmann, B.A.1    Lindner, J.R.2
  • 42
    • 8044253414 scopus 로고    scopus 로고
    • A novel site-targeted ultrasonic contrast agent with broad biomedical application
    • Lanza GM, Wallace KD, Scott MJ, et al. A novel site-targeted ultrasonic contrast agent with broad biomedical application. Circulation 1996; 94: 3334-3340.
    • (1996) Circulation , vol.94 , pp. 3334-3340
    • Lanza, G.M.1    Wallace, K.D.2    Scott, M.J.3
  • 43
    • 12344297823 scopus 로고    scopus 로고
    • RGD-modified liposomes targeted to activated platelets as a potential vascular drug delivery system
    • Gupta AS, Huang G, Lestini BJ, et al. RGD-modified liposomes targeted to activated platelets as a potential vascular drug delivery system. Thromb Haemost 2005; 93: 106-114.
    • (2005) Thromb Haemost , vol.93 , pp. 106-114
    • Gupta, A.S.1    Huang, G.2    Lestini, B.J.3
  • 44
    • 38049177399 scopus 로고    scopus 로고
    • Characterization of a novel bifunctional mutant of staphylokinase with platelet-targeted thrombolysis and antiplatelet aggregation activities
    • Chen H, Mo W, Su H, et al. Characterization of a novel bifunctional mutant of staphylokinase with platelet-targeted thrombolysis and antiplatelet aggregation activities. BMC molecular Biol 2007; 8: 88.
    • (2007) BMC Molecular Biol , vol.8 , pp. 88
    • Chen, H.1    Mo, W.2    Su, H.3
  • 45
    • 38449115704 scopus 로고    scopus 로고
    • Expression and intein-mediated purification of novel staphylokinase SakSTAR with reduced immunogenicity and antiplatelet and antithrombin activation
    • Kochanowski R, Kotlowski R, Szweda P. Expression and intein-mediated purification of novel staphylokinase SakSTAR with reduced immunogenicity and antiplatelet and antithrombin activation. Appl Biochem Biotechnol 2007; 141: 321-333.
    • (2007) Appl Biochem Biotechnol , vol.141 , pp. 321-333
    • Kochanowski, R.1    Kotlowski, R.2    Szweda, P.3


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