Liposomal Cu-64 labeling method using bifunctional chelators: Poly(ethylene glycol) spacer and chelator effects

Bioconjugate Chemistry

Volumn 21, Issue 7, 2010, Pages 1206-1215

  Seo, Jai Woong ^a   Mahakian, Lisa M ^a   Kheirolomoom, Azadeh ^a   Zhang, Hua ^a   Meares, Claude F ^b   Ferdani, Riccardo ^c   Anderson, Carolyn J ^c   Ferrara, Katherine W ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; COPPER COMPOUNDS; ETHYLENE GLYCOL; LIPOSOMES; POLYETHYLENE GLYCOLS; POLYOLS; RADIATION; RADIOACTIVITY;

BI-FUNCTIONAL; BLOOD POOL; CARBOXYMETHYL; HEXADECANE; IN-VIVO; LABELING METHODS; LONG-CIRCULATING LIPOSOMES; SYNTHESISED; TETRAACETIC ACID; TIME-ACTIVITY-CURVES;

CHELATION;

4 [2 (2 PYRIDYLITHIOETHYL)ETHANAMIDO] 11 CARBOXYMETHYL 1,4,8,11 TETRAAZABICYCLO[6.6.2]HEXADECANE; CHELATING AGENT; COPPER 64; LIPOSOME; MACROGOL; MALEIMIDE; UNCLASSIFIED DRUG; [6 [6 [3 (2 PYRIDYLITHIO)PROPIONAMIDO]HEXANAMIDO]BENZYL] 1,4,8,11 TETRA AZACYCLOTETRADECANE 1,4,8,11 TETRAACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CHELATION; COMPLEX FORMATION; CONJUGATION; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIVER; MOLECULAR STABILITY; MOUSE; NONHUMAN; PLASMA CLEARANCE; RADIOACTIVITY; SPLEEN; SYNTHESIS; TISSUE DISTRIBUTION;

EID: 77954866783     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc100018n     Document Type: Article

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