Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow

Journal of Controlled Release

Volumn 96, Issue 3, 2004, Pages 473-482

  Takalkar, Amol M ^a   Klibanov, Alexander L ^a,b   Rychak, Joshua J ^a   Lindner, Jonathan R ^b   Ley, Klaus ^a,c  

^a Cardiovascular Research Center   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Adhesion; Microbubbles; P selectin; Targeting; Ultrasound contrast

Indexed keywords

ANTIBODIES; ENZYME IMMOBILIZATION; ENZYME KINETICS; MONOLAYERS; SHEAR FLOW; SHEAR STRESS;

BINDING KINETICS; CONJUGATED MONOCLONAL ANTIBODIES; LIPID MONOLAYER SHELLS; MICROBUBBLES;

LIPIDS;

BIOTIN; CONTRAST MEDIUM; LIPID; MACROGOL; MONOCLONAL ANTIBODY; PADGEM PROTEIN; STREPTAVIDIN;

ARTICLE; BINDING KINETICS; CONTROLLED DRUG RELEASE; CULTURE MEDIUM; DENSITY; DRUG ACCUMULATION; DRUG COATING; DRUG CONJUGATION; DRUG DESIGN; DRUG EXPOSURE; DRUG TARGETING; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; SHEAR FLOW; SHEAR STRESS; SURFACE PROPERTY;

ANTIBODIES, MONOCLONAL; BIOTIN; CAPSULES; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; EXCIPIENTS; MICROSCOPY, VIDEO; P-SELECTIN; RHEOLOGY; SURFACE PROPERTIES; THERMODYNAMICS;

EID: 2142758635     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.03.002     Document Type: Article

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