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Volumn 141, Issue 2-3, 2007, Pages 321-333
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Expression and intein-mediated purification of novel staphylokinase SakSTAR with reduced immunogenicity and antiplatelet and antithrombin activation
a
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Author keywords
Hirudin; Intein mediated purification; Plasminogen activator; Staphylokinase; Thrombin
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Indexed keywords
ACIDS;
AGGLOMERATION;
AMINES;
AMINO ACIDS;
CHEMICAL ACTIVATION;
ESCHERICHIA COLI;
FUSION REACTIONS;
HEALTH;
NUCLEAR PHYSICS;
ORGANIC ACIDS;
PURIFICATION;
WEIGHT CONTROL;
ANTIBODY-BINDING;
ANTITHROMBIN ACTIVATION;
BIOLOGIC ACTIVITIES;
C-TERMINUS;
CHIMERIC PROTEINS;
EFFICIENT METHODS;
FUSION PROTEINS;
HIRUDIN;
IMMUNOGENICITY;
INHIBITION RATES;
INTEIN-MEDIATED PURIFICATION;
PLASMINOGEN ACTIVATOR;
PLASMINOGEN ACTIVATORS;
PLATELET AGGREGATION;
POINT MUTATIONS;
RGD SEQUENCES;
STAPHYLOKINASE;
THROMBIN;
THROMBIN INHIBITORS;
VASCULAR INJURIES;
GENE ENCODING;
ANTITHROMBIN;
ANTITHROMBOCYTIC AGENT;
ARGINYLGLYCYLASPARTIC ACID;
CHIMERIC PROTEIN;
HIRUDIN;
HYBRID PROTEIN;
INTEIN;
STAPHYLOKINASE;
ANTICOAGULANT AGENT;
AUR PROTEIN, STAPHYLOCOCCUS AUREUS;
FIBRIN;
HIRUDIN DERIVATIVE;
METALLOPROTEINASE;
PLASMINOGEN ACTIVATOR;
THROMBIN;
UNCLASSIFIED DRUG;
AMINO ACID SEQUENCE;
ANTIGEN BINDING;
ARTICLE;
ENZYME PURIFICATION;
ESCHERICHIA COLI;
GENE AMPLIFICATION;
GENE SEQUENCE;
IMMUNOGENICITY;
NONHUMAN;
POINT MUTATION;
PROTEIN EXPRESSION;
PROTEIN PURIFICATION;
THROMBOCYTE AGGREGATION INHIBITION;
BIOLOGICAL MODEL;
CHEMISTRY;
DNA SEQUENCE;
DOSE RESPONSE;
FIBRINOLYSIS;
HUMAN;
METABOLISM;
MOLECULAR GENETICS;
PLASMID;
THROMBOCYTE;
TIME;
ESCHERICHIA COLI;
AMINO ACID SEQUENCE;
ANTICOAGULANTS;
ANTITHROMBINS;
BLOOD PLATELETS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
FIBRIN;
FIBRINOLYSIS;
HIRUDINS;
HUMANS;
INTEINS;
METALLOENDOPEPTIDASES;
MODELS, BIOLOGICAL;
MOLECULAR SEQUENCE DATA;
PLASMIDS;
PLASMINOGEN ACTIVATORS;
PLATELET AGGREGATION INHIBITORS;
POINT MUTATION;
RECOMBINANT FUSION PROTEINS;
SEQUENCE ANALYSIS, DNA;
THROMBIN;
TIME FACTORS;
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EID: 38449115704
PISSN: 02732289
EISSN: None
Source Type: Journal
DOI: 10.1007/BF02729070 Document Type: Article |
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Times cited : (4)
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References (22)
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