CD22 serves as a receptor for soluble IgM

European Journal of Immunology

Volumn 42, Issue 1, 2012, Pages 241-247

  Adachi, Takahiro ^a   Harumiya, Satoru ^a   Takematsu, Hiromu ^b   Kozutsumi, Yasunori ^b   Wabl, Matthias ^c   Fujimoto, Manabu ^d   Tedder, Thomas F ^e  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

B cells; CD22; Fc receptor; IgM; Siglec 2

Indexed keywords

BETA GALACTOSIDE ALPHA 2,6 SIALYLTRANSFERASE; CD22 ANTIGEN; CROSSOVER JUNCTION ENDODEOXYRIBONUCLEASE; FC RECEPTOR IIB; IMMUNOGLOBULIN M; SIALYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; B LYMPHOCYTE ACTIVATION; COMPLEX FORMATION; CONTROLLED STUDY; FEEDBACK SYSTEM; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION;

ANIMALS; ANTIGENS, CD22; B-LYMPHOCYTES; BLOTTING, WESTERN; CELL LINE, TUMOR; FEEDBACK; FLOW CYTOMETRY; IMMUNOGLOBULIN M; LIGANDS; MICE; MICE, KNOCKOUT; RECEPTORS, ANTIGEN, B-CELL;

EID: 84855245308     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141899     Document Type: Article

References (33)

1. Cyster, J. G. and Goodnow, C. C., Tuning antigen receptor signaling by CD22: integrating cues from antigens and the microenvironment. Immunity 1997. 6: 509-517.
2. Tedder, T. F., Tuscano, J., Sato, S. and Kehrl, J. H., CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu. Rev. Immunol. 1997. 15: 481-504.
3. Walker, J. A. and Smith, K. G., CD22: an inhibitory enigma. Immunology 2008. 123: 314-325.
4. Zhu, C., Sato, M., Yanagisawa, T., Fujimoto, M., Adachi, T. and Tsubata, T., Novel binding site for Src homology 2-containing protein-tyrosine phosphatase-1 in CD22 activated by B lymphocyte stimulation with antigen. J. Biol. Chem. 2008. 283: 1653-1659.
5. Doody, G. M., Justement, L. B., Delibrias, C. C., Matthews, R. J., Lin, J., Thomas, M. L. and Fearon, D. T., A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. Science 1995. 269: 242-244.
6. Nitschke, L., Carsetti, R., Ocker, B., Kohler, G. and Lamers, M. C., CD22 is a negative regulator of B-cell receptor signalling. Curr. Biol. 1997. 7: 133-143.
7. O'Keefe, T. L., Williams, G. T., Davies, S. L. and Neuberger, M. S., Hyperresponsive B cells in CD22-deficient mice. Science 1996. 274: 798-801.
8. Otipoby, K. L., Andersson, K. B., Draves, K. E., Klaus, S. J., Farr, A. G., Kerner, J. D., Perlmutter, R. M. et al., CD22 regulates thymus-independent responses and the lifespan of B cells. Nature 1996. 384: 634-637.
9. Sato, S., Miller, A. S., Inaoki, M., Bock, C. B., Jansen, P. J., Tang, M. L. and Tedder, T. F., CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 1996. 5: 551-562.
10. Crocker, P. R., Paulson, J. C. and Varki, A., Siglecs and their roles in the immune system. Nat. Rev. Immunol. 2007. 7: 255-266.
11. Hanasaki, K., Powell, L. D. and Varki, A., Binding of human plasma sialoglycoproteins by the B cell-specific lectin CD22. Selective recognition of immunoglobulin M and haptoglobin. J. Biol. Chem. 1995. 270: 7543-7550.
12. Zhang, M. and Varki, A., Cell surface sialic acids do not affect primary CD22 interactions with CD45 and surface IgM nor the rate of constitutive CD22 endocytosis. Glycobiology 2004. 14: 939-949.
13. Han, S., Collins, B. E., Bengtson, P. and Paulson, J. C., Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking. Nat. Chem. Biol. 2005. 1: 93-97.
14. Lanoue, A., Batista, F. D., Stewart, M. and Neuberger, M. S., Interaction of CD22 with alpha2, 6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity? Eur. J. Immunol. 2002. 32: 348-355.
15. Courtney, A. H., Puffer, E. B., Pontrello, J. K., Yang, Z. Q. and Kiessling, L. L., Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation. Proc. Natl. Acad. Sci. USA 2009. 106: 2500-2505.
16. Yu, J., Sawada, T., Adachi, T., Gao, X., Takematsu, H., Kozutsumi, Y., Ishida, H. et al., Synthetic glycan ligand excludes CD22 from antigen receptor-containing lipid rafts. Biochem. Biophys. Res. Commun. 2007. 360: 759-764.
17. Cascalho, M., Ma, A., Lee, S., Masat, L. and Wabl, M., A quasi-monoclonal mouse. Science 1996. 272: 1649-1652.
18. Adachi, T., Flaswinkel, H., Yakura, H., Reth, M. and Tsubata, T., The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation. J. Immunol. 1998. 160: 4662-4665.
19. Ono, M., Bolland, S., Tempst, P. and Ravetch, J. V., Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB. Nature 1996. 383: 263-266.
20. Muta, T., Kurosaki, T., Misulovin, Z., Sanchez, M., Nussenzweig, M. C. and Ravetch, J. V., A 13-amino-acid motif in the cytoplasmic domain of Fc gamma RIIB modulates B-cell receptor signalling. Nature 1994. 368: 70-73.
21. Kurosaki, T., Genetic analysis of B cell antigen receptor signaling. Annu. Rev. Immunol. 1999. 17: 555-592.
22. Rickert, R. C., Regulation of B lymphocyte activation by complement C3 and the B cell coreceptor complex. Curr. Opin. Immunol. 2005. 17: 237-243.
23. Shima, H., Takatsu, H., Fukuda, S., Ohmae, M., Hase, K., Kubagawa, H., Wang, J. Y. et al., Identification of TOSO/FAIM3 as an Fc receptor for IgM. Int. Immunol. 2010. 22: 149-156.
24. Kubagawa, H., Oka, S., Kubagawa, Y., Torii, I., Takayama, E., Kang, D. W., Gartland, G. L. et al., Identity of the elusive IgM Fc receptor (FcμR) in humans. J. Exp. Med. 2009. 206: 2779-2793.
25. Batista, F. D., Iber, D. and Neuberger, M. S., B cells acquire antigen from target cells after synapse formation. Nature 2001. 411: 489-494.
26. Ehrenstein, M. R., Cook, H. T. and Neuberger, M. S., Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies. J. Exp. Med. 2000. 191: 1253-1258.
27. O'Keefe, T. L., Williams, G. T., Batista, F. D. and Neuberger, M. S., Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J. Exp. Med. 1999. 189: 1307-1313.
28. Wakabayashi, C., Adachi, T., Wienands, J. and Tsubata, T., A distinct signaling pathway used by the IgG-containing B cell antigen receptor. Science 2002. 298: 2392-2395.
29. Adachi, T., Wienands, J., Wakabayashi, C., Yakura, H., Reth, M. and Tsubata, T., SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates. J. Biol. Chem. 2001. 276: 26648-26655.
30. Morita, S., Kojima, T. and Kitamura, T., Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 2000. 7: 1063-1066.
31. Hokazono, Y., Adachi, T., Wabl, M., Tada, N., Amagasa, T. and Tsubata, T., Inhibitory coreceptors activated by antigens but not by anti-Ig heavy chain antibodies install requirement of costimulation through CD40 for survival and proliferation of B cells. J. Immunol. 2003. 171: 1835-1843.
32. Sato, M., Adachi, T. and Tsubata, T., Augmentation of signaling through BCR containing IgE but not that containing IgA due to lack of CD22-mediated signal regulation. J. Immunol. 2007. 178: 2901-2907.
33. Reth, M., Hammerling, G. J. and Rajewsky, K., Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response. Eur. J. Immunol. 1978. 8: 393-400.