Tuning antigen receptor signaling by CD22: Integrating cues from antigens and the microenvironment

Immunity

Volumn 6, Issue 5, 1997, Pages 509-517

  Cyster, Jason G ^a   Goodnow, Christopher C ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD22 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

B LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0030950344     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80339-8     Document Type: Review

References (73)

1. Ahearn, J.M., Fischer, M.B., Croix, D., Goerg, S., Ma, M., Xia, J., Zhou, X., Howard, R.G., Rothstein, T.L., and Carroll, M.C. (1996). Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen. Immunity 4, 251-262.
2. Andersson, K.B., Draves, K.E., Magaletti, D.M., Fugioka, S., Holmes, K.L., Law, C.-L., and Clark, E.A. (1996). Characterization of the expression and gene promoter of CD22 in murine B cells. Eur. J. Immunol. 26, 3170-3178.
3. Aruffo, A., Kanner, S.B., Sgroi, D., Ledbetter, J.A., and Stamenkovic, I. (1992). CD22-mediated stimulation of T cells regulates T-cell receptor/CD3-induced signaling. Proc. Natl. Acad. Sci. USA 89, 10242-10246.
4. Bachmann, M.F., Odermatt, B., Hengartner, H., and Zinkernagel, R.M. (1996). Induction of long-lived germinal centers associated with persisting antigen after viral infection. J. Exp. Med. 183, 2259-2269.
5. Bikah, G., Carey, J., Ciallella, J.R., Tarakhovsky, A., and Bondada, S. (1996). CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells. Science 274, 1906-1909.
6. Braesch-Andersen, S., and Stamenkovic, I. (1994). Sialylation of the B lymphocyte molecule CD22 by alph2,6-sialyltransferase is implicated in the regulation of CD22-mediated adhesion. J. Biol. Chem. 269, 11783-11786.
7. Burshtyn, D.N., Scharenberg, A.M., Wagtmann, N., Rajagopalan, S., Berrada, K., Yi, T., Kinet, J.P., and Long, E.O. (1996). Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor. Immunity 4, 77-85.
8. Campana, D., Janossy, G., Bofill, M., Trejdosiewicz, L.K., Ma, D., Hoffbrand, A.V., Mason, D.Y., Lebacq, A.-M., and Forster, H.K. (1985). Human B cell development. I. Phenotypic differences of B lymphocytes in the bone marrow and peripheral lymphoid tissue. J. Immunol. 134, 1524-1530.
9. Campbell, M.A., and Klinman, N.R. (1995). Phosphotyrosine-dependent association between CD22 and protein tyrosine phosphatase 1C. Eur. J. Immunol. 25, 1573-1579.
10. Chan, A.C., Desai, D.M., and Weiss, A. (1994). The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu. Rev. Immunol. 12, 555-592.
11. Cyster, J.G., and Goodnow, C.C. (1995a). Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity 2, 13-24.
12. Cyster, J.G., and Goodnow, C.C. (1995b). Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate. Immunity 3, 691-701.
13. Cyster, J.G., Hartley, S.B., and Goodnow, C.C. (1994). Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 371, 389-395.
14. Cyster, J.G., Healy, J.I., Kishihara, K., Mak, T.W., Thomas, M.L., and Goodnow, C.C. (1996). Regulation of B-lymphocyte negative and positive selection by tryosine phosphatase CD45. Nature 381, 325-328.
15. D'Ambrosio, D., Hippen, K.L., Minskoff, S.A., Mellman, I., Pani, G., Siminovitch, K.A., and Cambier, J.C. (1995). Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB1. Science 268, 293-297.
16. Desai, D.M., Sap, J., Schlessinger, J., and Weiss, A. (1993). Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell 73, 541-554.
17. Doody, G.M., Justement, L.B., Delibrias, C.C., Matthews, R.J., Lin, J., Thomas, M.L., and Fearon, D.T. (1995). A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. Science 269, 242-244.
18. Dorken, B., Moldenhauer, G., Pezzutto, A., Schwartz, R., Feller, A., Kiesel, S., and Nadler, L.M. (1986). HD39 (B3), a B lineage-restricted antigen whose cell surface expression is limited to resting and activated human B lymphocytes. J. Immunol. 135, 4470-4479.
19. Engel, P., Wagner, N., Miller, A.S., and Tedder, T.F. (1995). Identification of the ligand-binding domains of CD22, a member of the immunoglobulin superfamily that uniquely binds a sialic acid-dependent ligand. J. Exp. Med. 181, 1581-1586.
20. Erickson, L.D., Tygrett, L.T., Bhatia, S.K., Grabstein, K.H., and Waldschmidt, T.J. (1996). Differential expression of CD22 (Lyb8) on murine B cells. Int. Immunol. 8, 1121-1129.
21. Erikstein, B.K., Funderud, S., Beiske, K., Aas-Eng, A., De Lange Davies, C., Blomhoff, H.K., and Smeland, E.B. (1992). Cell cycle-dependent regulation of CDw75 (beta-galactoside alpha-2,6-sialyltransferase) on human B lymphocytes. Eur. J. Immunol. 22, 1149-1155.
22. Fearon, D.T., and Carter, R.H. (1995). The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity. Annu. Rev. Immunol. 13, 127-149.
23. Fulcher, D.A., Lyons, A.B., Korn, S.L., Cook, M.C., Koleda, C., Parish, C., Fazekas de St. Groth, B., and Basten, A. (1996). The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help. J. Exp. Med. 183, 2329-2336.
24. Gold, M.R., and DeFranco, A.L. (1994). Biochemistry of B lymphocyte activation. Adv. Immunol. 55, 221-295.
25. Goodnow, C.C., Crosbie, J., Jorgensen, H., Brink, R.A., and Basten, A. (1989). Induction of self-tolerance in mature peripheral B lymphocytes. Nature 342, 385-391.
26. Goodnow, C.C., Cyster, J.G., Hartley, S.B., Bell, S.E., Cooke, M.P., Healy, J.I., Akkaraju, S., Rathmell, J.C., Pogue, S.L., and Shokat, K.P. (1995). Self-tolerance checkpoints in B lymphocyte development. Adv. Immunol. 59, 279-368.
27. Hanasaki, K., Powell, L.D., and Varki, A. (1995). Binding of human plasma sialoglycoproteins by the B cell-specific lectin CD22. J. Biol. Chem. 270, 7543-7550.
28. Hibbs, M.L., Tarlinton, D.M., Armes, J., Grail, D., Hodgson, G., Maglitto, R., Stacker, S.A., and Dunn, A.R. (1995). Multiple defects in the immune system of Lyn-deficient mice, cluminating in autoimmune disease. Cell 83, 301-311.
29. Kantor, A.B., and Herzenberg, L.A. (1993). Origin of murine B cell lineages. Annu. Rev. Immunol. 11, 501-538.
30. Kishihara, K., Penninger, J., Wallace, W.A., Kundig, T.M., Kawai, K., Wakeham, A., Timms, E., Pfeffer, K., Ohashi, P.S., Thomas, M.L., et al. (1993). Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phophatase-deficient mice. Cell 74, 143-156.
31. Law, C.L., Aruffo, A., Chandran, K.A., Doty, R.T., and Clark, E.A. (1995). Ig domains 1 and 2 of murine CD22 constitute the ligand-binding domain and bind multiple sialylated ligands expressed on B and T cells. J. Immunol. 155, 3368-3376.
32. Law, C.L., Sidorenko, S.P., Chandran, K.A., Zhao, Z., Shen, S.H., Fischer, E.H., and Clark, E.A. (1996). CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation. J. Exp. Med. 183, 547-560.
33. Leitenberg, D., Novak, T.J., Farber, D., Smith, B.R., and Bottomly, K. (1996). The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation. J. Exp. Med. 183, 249-259.
34. Leprince, C., Draves, K.E., Geahlen, R.L., Ledbetter, J.A., and Clark, E.A. (1993). CD22 associates with the human surface IgM-B cell antigen receptor complex. Proc.Natl. Acad. Sci. USA 90, 3236-3240.
35. Liu, Y.-J., Zhang, J., Lane, P.J.L., Chan, E.Y.-T., and MacLennan, I.C.M. (1991). Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 21, 2951-2962.
36. Loken, M.R., Shah, O.S., Dattilio, K.L., and Civin, C.I. (1987). Flow cytometric analysis of human bone marrow. II. Normal B lymphocyte development. Blood 70, 1316-1324.
37. Molina, H., Holers, V.M., Li, B., Fung, Y., Mariathasan, S., Goellner, J., Strauss-Schoenberger, J., Karr, R.W., and Chaplin, D.D. (1996). Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2. Proc. Natl. Acad. Sci. USA 93, 3357-3361.
38. Morris, D.L., and Rothstein, T.L. (1993). Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes. J. Exp. Med. 177, 857-861.
39. Nishizumi, H., Taniuchi, I., Yamanashi, Y., Kitamura, D., Ilic, D., Mori, S., Watanabe, T., and Yamamoto, T. (1995). Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. Immunity 3, 549-60.
40. Nitschke, L., Carsetti, R., Ocker, B., Kohler, G., and Lamers, M.C. (1997). CD22 is a negative regulator of B cell receptor signaling. Curr. Biol. 7, 133-143.
41. O'Keefe, T.L., Williams, G.T., Davies, S.L., and Neuberger, M.S. (1996). Hyperresponsive B cells in CD22-deficient mice. Science 274, 798-801.
42. Ono, M., Bolland, S., Tempst, P., and Ravetch, J.V. (1996). Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB. Nature 383, 263-266.
43. Otipoby, K.L., Andersson, K.B., Draves, K.E., Klaus, S.J., Garr, A.G., Kerner, J.D., Perlmutter, R.M., Law, C.-L., and Clark, E.A. (1996). CD22 regulates thymus independent responses and the lifespan of B cells. Nature 384, 634-637.
44. Pani, G., Kozlowski, M., Cambier, J.C., Mills, G.B., and Siminovitch, K.A. (1995). Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling. J. Exp. Med. 181, 2077-2084.
45. Peaker, C.J., and Neuberger, M.S. (1993). Association of CD22 with the B cell antigen receptor. Eur. J. Immunol. 23, 1358-1363.
46. Pezzutto, A., Dorken, B., Moldenhauer, G., and Clark, E.A. (1987). Amplification of human B cell activation by a monoclonal antibody to the B cell-specific antigen CD22, Bp 130/140. J. Immunol. 138, 98-103.
47. Pezzutto, A., Rabinovitch, P.S., Dorken, B., Moldenhauer, G., and Clark, E.A. (1988). Role of the CD22 human B cell antigen in B cell triggering by anti-immunoglobulin. J. Immunol. 140, 1791-1795.
48. Ravetch, J.V., and Kinet, J.P. (1991). Fc receptors. Annu. Rev. Immunol. 9, 457-492.
49. Reth, M. (1992). Antigen receptors on B lymphocytes. Annu. Rev. Immunol. 10, 97-121.
50. Rickert, R.C., Rajewsky, K., and Roes, J. (1995). Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Nature 376, 352-355.
51. Sato, S., Miller, A.S., Inaoki, M., Bock, C.B., Jansen, P.J., Tang, M.L., and Tedder, T.F. (1996). CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 5, 551-562.
52. Scharenberg, A.M., and Kinet, J.P. (1996). The emerging field of receptor-mediated inhibitory signaling: SHP or SHIP? Cell 87, 961-964.
53. Schulte, R.J., Campbell, M.-A., Fischer, W.H., and Sefton, B.M. (1992). Tyrosine phosphorylation of CD22 during B cell activation. Science 258, 1001-1004.
54. Sgroi, D., Varki, A., Braesch-Andersen, S., and Stamenkovic, I. (1993). CD22, aB cell-specific immunoglobulin superfamily member, is a sialic acid-binding lectin. J. Biol. Chem. 268, 7011-7018.
55. Shokat, K.M., and Goodnow, C.C. (1995). Antigen-induced B-cell death and elimination during germinal center immune responses. Nature 375, 334-338.
56. Sidman, C.L., Shultz, L.D., Hardy, R.R., Hayakawa, K., and Herzenberg, L.A. (1986). Production of immunoglobulin isotypes by Ly-1 + B cells in viable motheaten and normal mice. Science 232, 1423-1425.
57. Sjoberg, E.R., Powell, L.D., Klein, A., and Varki, A. (1994). Natural ligands of the B cell adhesion molecule CD22beta can be masked by 9-O-acetylation of sialic acids. J. Cell Biol. 126, 549-562.
58. Stamenkovic, I., and Seed, B. (1990). The B-cell antigen CD22 mediates monocyte and erythrocyte adhesion. Nature 345, 74-77.
59. Stamenkovic, I., Sgroi, D., Aruffo, A., Sy, M.S., and Anderson, T. (1991). The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and α2-6 sialyltransferase, CD75, on B cells. Cell 66, 1133-1144.
60. Tarakhovsky, A., Kanner, S.B., Hombach, J., Ledbetter, J.A., Muller, W., Killeen, N., and Rajewsky, K. (1995). A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science 269, 535-537.
61. Tedder, T.F., Inaoki, M., and Sato, S. (1997). The CD19-CD21 complex of B lymphocytes regulates signal transduction thresholds governing humoral immunity and autoimmunity. Immunity 6, 107-118.
62. Torres, R.M., Law, C.L., Santos-Argumedo, L., Kirkham, P.A., Grabstein, K., Parkhouse, R.M., and Clark, E.A. (1992). Identification and characterization of the murine homologue of CD22, a B lymphocyte-restricted adhesion molecule. J. Immunol. 149, 2641-2649.
63. Torres, R.M., Flaswinkel, H., Reth, M., and Rajewsky, K. (1996). Aberrant B cell development and immune response in mice with a compromised BCR complex. Science 272, 1804-1808.
64. Trowbridge, I.S., and Thomas, M.L. (1994). CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 12, 85-116.
65. Tuscano, J., Engel, P., Tedder, T.F., and Kehrl, J.H. (1996a). Engagement of the adhesion receptor CD22 triggers a potent stimulatory signal for B cells and blocking CD22/CD22L interactions impairs T-cell proliferation. Blood 87, 4723-4730.
66. Tuscano, J.M., Engel, P., Tedder, T.F., Agarwal, A., and Kehrl, J.H. (1996b). Involvement of p72syk kinase, p53/56lyn kinase and phosphatidyl inositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22. Eur. J. Immunol. 26, 1246-1252.
67. van der Merwe, A., and Barclay, A.N. (1994). Transient intercellular adhesion: the importance of weak protein-protein interactions. TIBS 19, 354-358.
68. van der Merwe, A., Crocker, P.R., Vinson, M., Barclay, A.N., Schauer, R., and Kelm, S. (1996). Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22. J. Biol. Chem. 271, 9273-9280.
69. Wang, J., Koizumi, T., and Watanabe, T. (1996). Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice. J. Exp. Med. 184, 831-838.
70. Weiss, A., and Littman, D.R. (1994). Signal transduction by lymphocyte antigen receptors. Cell 76, 263-274.
71. Williams, G.T., Peaker, C.J., Patel, K.J., and Neuberger, M.S. (1994). The alpha/beta sheath and its cytoplasmic tyrosines are required for signaling by the B-cell antigen receptor but not for capping or for serine/threonine-kinase recruitment. Proc. Natl. Acad. Sci. USA 91, 474-478.
72. Wilson, G.L., Fox, C.H., Fauci, A.S., and Kehrl, J.H. (1991). cDNA cloning of the B cell membrane protein CD22: a mediator of B-B cell interactions. J. Exp. Med. 173, 137-146.
73. Yellen, A.J., Glenn, W., Sukhatme, V.P., Cao, S.M., and Monroe, J.G. (1991). Signaling through surface IgM in tolerance-susceptible immature murine B lymphocytes: developmentally regulated difference in transmembrane signaling in splenic B cells from adult and neonatal mice. J. Immunol. 146, 1446-1454.