Wnt/β-catenin pathway forms a negative feedback loop during TGF-β1 induced human normal skin fibroblast-to-myofibroblast transition

Journal of Dermatological Science

Volumn 65, Issue 1, 2012, Pages 38-49

  Liu, Jiaqi ^a   Wang, Yunchuan ^a   Pan, Qing ^b   Su, Yingjun ^a   Zhang, Zhanfeng ^a   Han, Juntao ^a   Zhu, Xiongxiang ^a   Tang, Chaowu ^a   Hu, Dahai ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b ROCKET FORCE UNIVERSITY OF ENGINEERING   (China)

Author keywords

Betacatenin; Fibroblast; Hypertrophic scar; Myofibroblast; Transforming growth factor beta 1; Wound healing

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; ALPHA SMOOTH MUSCLE ACTIN; BETA CATENIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; MESSENGER RNA; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; WNT PROTEIN;

ARTICLE; CELL STIMULATION; CELL TRANSFORMATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERTROPHIC SCAR; IMMUNOCYTOCHEMISTRY; MYOFIBROBLAST; NEGATIVE FEEDBACK; PHENOTYPIC PLASTICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; SMOOTH MUSCLE CONTRACTILITY; UPREGULATION; WESTERN BLOTTING;

BETA CATENIN; BLOTTING, WESTERN; CELLS, CULTURED; CICATRIX, HYPERTROPHIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FEEDBACK, PHYSIOLOGICAL; FIBROBLASTS; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, FLUORESCENCE; MYOFIBROBLASTS; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN; TIME FACTORS; WNT PROTEINS; WOUND HEALING;

EID: 84855201504     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2011.09.012     Document Type: Article

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