The effect of myofibroblast on contracture of hypertrophic scar

Plastic and Reconstructive Surgery

Volumn 113, Issue 2, 2004, Pages 633-640

  Shin, Dongmin ^a,b   Minn, Kyung Won ^a,b  

^a Seoul National University ^*

^b Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; TRANILAST; ACTIN; ANTHRANILIC ACID DERIVATIVE;

ADULT; APOPTOSIS; ARTICLE; CELL ISOLATION; CONTRACTURE; DERMIS; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTROPHIC SCAR; MYOFIBROBLAST; PRIORITY JOURNAL; SKIN CULTURE; SMOOTH MUSCLE FIBER; WOUND CONTRACTION; WOUND HEALING; CELL CULTURE; CHEMISTRY; CULTURE MEDIUM; DRUG EFFECT; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MYOBLAST; PATHOPHYSIOLOGY; PHYSIOLOGY;

ACTINS; ADULT; ANTHRANILIC ACIDS; CELLS, CULTURED; CICATRIX, HYPERTROPHIC; COLLAGEN; CULTURE MEDIA; FEMALE; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; MYOBLASTS, SMOOTH MUSCLE; WOUND HEALING;

EID: 1442288565     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.PRS.0000101530.33096.5B     Document Type: Article

References (33)

1. Engrav, L. H., Covey, M. H., Dutcher, K. D., Heimbach, D. M., Walkinshaw, M. D., and Marvin, J. A. Impairment, time out of school, and time off from work after burns. Plast. Reconstr. Surg. 79: 927, 1987.
2. Rowlatt, U. Intrauterine wound healing in a 20-week human fetus. Virchows Arch. A Pathol. Anat. Histol. 381: 353, 1979.
3. Tredget, E. E., Nedelec, B., Scott, P. G., and Ghahary, A. Hypertrophic scars, keloids, and contractures: The cellular and molecular basis for therapy. Surg. Clin. North Am. 77: 701, 1997.
4. Rudolph, R., Guber, S., Suzuki, M., and Woodward, M. The life cycle of the myofibroblast. Surg. Gynecol. Obstet. 145: 389, 1977.
5. Gabbiani, G. The cellular derivation and the life span of the myofibroblast. Pathol. Res. Pract. 192: 708, 1996.
6. Ehrlich, H. P., Desmouliere, A., Diegelmann, R. F., et al. Morphological and immunochemical differences between keloid and hypertrophic scar. Am. J. Pathol. 145: 105, 1994.
7. Suzawa, H., Kikuchi, S., Arai, N., and Koda, A. The mechanism involved in the inhibitory action of tranilast on collagen biosynthesis of keloid fibroblasts. Jpn. J. Pharmacol. 60: 91, 1992.
8. Yamada, H., Tajima, S., Nishikawa, T., Murad, S., and Pinnell, S. R. Tranilast, a selective inhibitor of collagen synthesis in human skin fibroblasts. J. Biochem. (Tokyo) 116: 892, 1994.
9. Cruz, N. I., and Korchin, L. Inhibition of human keloid fibroblast growth by isotretinoin and triamcinolone acetonide in vitro. Ann. Plast. Surg. 33: 401, 1994.
10. Hu, D., Hughes, M. A., and Cherry, G. W. Topical tamoxifen: A potential therapeutic regime in treating excessive dermal scarring? Br. J. Plast. Surg. 51: 462, 1998.
11. Diegelmann, R. F., Cohen, I. K., and McCoy, B. J. Growth kinetics and collagen synthesis of normal skin, normal scar and keloid fibroblasts in vitro. J. Cell. Physiol. 98: 341, 1979.
12. Tsai, C., Hata, K., Tori, S., Matsuyama, M., and Ueda, M. Contraction potency of hypertrophic scar-derived fibroblasts in a connective tissue model: In vitro analysis of wound contraction. Ann. Plast. Surg. 35: 638, 1995.
13. Van Winkle, W., Jr. Wound contraction. Surg. Gynecol. Obstet. 125: 131, 1967.
14. Nedelec, B., Ghahary, A., Scott, P. G., and Tredget, E. E. Control of wound contraction: Basic and clinical features. Hand Clin. 16: 289, 2000.
15. Ehrlich, H. P., and Rajaratnam, J. B. Cell locomotion forces versus cell contraction forces for collagen lattice contraction: An in vitro model of wound contraction. Tissue Cell. 22: 407, 1990.
16. Arora, P. D., and McCulloch, C. A. Dependence of collagen remodeling on alpha-smooth muscle actin expression by fibroblasts. J. Cell. Physiol. 159: 161, 1994.
17. Gabbiani, G., Ryan, G. B., and Majne, G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Expenentia 27: 549, 1971.
18. Gabbiani, G., Hirschel, B. J., Ryan, G. B., Statkov, P. R., and Majno, G. Granulation tissue as a contractile organ: A study of structure and function. J. Exp. Med. 135: 719, 1972.
19. Montandon, D., Gabbiani, G., Ryan, G. B., and Majno, G. The contractile fibroblast: Its relevance in plastic surgery. Plast. Reconstr. Surg. 52: 286, 1973.
20. Ryan, G. B., Cliff, W. J., Gabbiani, G., et al. Myofibroblasts in human granulation tissue. Hum. Pathol. 5: 55, 1974.
21. Sappino, A. P., Schurch, W., and Gabbiani, G. Differentiation repertoire of fibroblastic cells: Expression of cytoskeletal proteins as marker of phenotypic modulations. Lab. Invest. 63: 144, 1990.
22. Masur, S. K., Dewal, H. S., Dinh, T. T., Erenburg, I., and Petridou, S. Myofibroblasts differentiate from fibroblasts when plated at low density. Proc. Natl. Acad. Sci. U.S.A. 93: 4219, 1996.
23. Khan, I. A., and Kasper, L. H. IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice. J. Immunol. 157: 2103, 1996.
24. Ramirez, A. T., Soroff, H. S., Schwartz, M. S., Mooty, J., Pearson, E., and Raben, M. S. Experimental wound healing in man. Surg. Gynecol. Obstet. 128: 283, 1969.
25. Bell, E., Ivarsson, B., and Merrill, C. Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc. Natl. Acad. Sci. U.S.A. 76: 1274, 1979.
26. Grinnell, F., and Lamke, C. R. Reorganization of hydrated collagen lattices by human skin fibroblasts. J. Cell Sci. 66: 51, 1984.
27. Ignotz, R. A., and Massague, J. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J. Biol. Chem. 261: 4337, 1986.
28. Bassols, A., and Massague, J. Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans. J. Biol. Chem. 263: 3039, 1988.
29. Edwards, D. R., Murphy, G., Reynolds, J. J., et al. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J. 6: 1899, 1987
30. Overall, C. M., Wrana, J. L., and Sodek, J. Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta. J. Biol. Chem. 264: 1860, 1989.
31. Desmouliere, A., Geinoz, A., Gabbiani, F., and Gabbiani, G. Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J. Cell Biol. 122: 103, 1993.
32. Isaji, M., Aruga, N., Naito, J., and Miyata, H. Inhibition by tranilast of collagen accumulation in hypersensitive granulomatous inflammation in vivo and of morphological changes and functions of fibroblasts in vitro. Life Sci. 55: 287, 1994.
33. Smith, P., Mosiello, G., Deluca, L., Ko, F., Maggi, S., and Robson, M. C. TGF-beta2 activates proliferative scar fibroblasts. J. Surg. Res. 82: 319, 1999.