Quantitative NMR spectroscopy of supramolecular complexes: Dynamic side pores in ClpP are important for product release

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 46, 2005, Pages 16678-16683

  Sprangers, Remco ^a,b   Gribun, Anna ^a   Hwang, Peter M ^a   Houry, Walid A ^a   Kay, Lewis E ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

ClpP protease; Methyl transverse relaxation optimized spectroscopy; Protein dynamics

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CELL PROTEIN; ENDOPEPTIDASE CLP; ENDOPEPTIDASE CLPA; ENDOPEPTIDASE CLPX; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; QUANTITATIVE ANALYSIS; STREPTOCOCCUS PNEUMONIAE; SUPRAMOLECULAR CHEMISTRY; THERMODYNAMICS;

ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASE CLP; ESCHERICHIA COLI PROTEINS; KINETICS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; THERMODYNAMICS;

STREPTOCOCCUS PNEUMONIAE;

EID: 28044440088     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0507370102     Document Type: Article

References (30)

1. Wang, J., Hartling, J. A. & Flanagan, J. M. (1997) Cell 91, 447-456.
2. Wickner, S., Maurizi, M. R. & Gottesman, S. (1999) Science 286, 1888-1893.
3. Pickart, C. M. & Cohen, R. E. (2004) Nat. Rev. Mol. Cell Biol. 5, 177-187.
4. Bochtler, M., Ditzel, L., Groll, M. & Huber, R. (1997) Proc. Natl. Acad. Sci. USA 94, 6070-6074.
5. Lowe, J., Stock, D., Jap, B., Zwickl, P., Baumeister, W. & Huber, R. (1995) Science 268, 533-539.
6. Groll, M., Ditzel, L., Lowe, J., Stock, D., Bochtler, M., Bartunik, H. D. & Huber, R. (1997) Nature 386, 463-471.
7. Ortega, J., Singh, S. K., Ishikawa, T., Maurizi, M. R. & Steven, A. C. (2000) Mol. Cell 6, 1515-1521.
8. Sauer, R. T., Bolon, D. N., Burton, B. M., Burton, R. E., Flynn, J. M., Grant, R. A., Hersch, G. L., Joshi, S. A., Kenniston, J. A., Levchenko, I., et al. (2004) Cell 119, 9-18.
9. Thompson, M. W., Singh, S. K. & Maurizi, M. R. (1994) J. Biol. Chem. 269, 18209-18215.
10. Kim, Y. I., Burton, R. E., Burton, B. M., Sauer, R. T. & Baker, T. A. (2000) Mol. Cell 5, 639-648.
11. Babbitt, S. E., Kiss, A., Deffenbaugh, A. E., Chang, Y. H., Bailly, E., Erdjument-Bromage, H., Tempst, P., Buranda, T., Sklar, L. A., Baumler, J., et al. (2005) Cell 121, 553-565.
12. Ortega, J., Lee, H. S., Maurizi, M. R. & Steven, A. C. (2004) J. Struct. Biol. 146, 217-226.
13. Gribun, A., Kimber, M. S., Ching, R., Sprangers, R., Fiebig, K. M. & Houry, W. A. (2005) J. Biol. Chem. 280, 16158-16196.
14. Tugarinov, V., Hwang, P. M., Ollerenshaw, J. E. & Kay, L. E. (2003) J. Am. Chem. Soc. 125, 10420-10428.
15. Tugarinov, V., Hwang, P. M. & Kay, L. E. (2004) Annu. Rev. Biochem. 73, 107-146.
16. Goto, N. K., Gardner, K. H., Mueller, G. A., Willis, R. C. & Kay, L. E. (1999) J. Biomol. NMR 13, 369-374.
17. Flanagan, J. M., Wall, J. S., Capel, M. S., Schneider, D. K. & Shanklin, J. (1995) Biochemistry 34, 10910-10917.
18. Gardner, K. H. & Kay, L. E. (1997) J. Am. Chem. Soc. 119, 7599-7600.
19. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J. & Bax, A. (1995) J. Biomol. NMR 6, 277-293.
20. Korzhnev, D. M., Kloiber, K., Kanelis, V., Tugarinov, V. & Kay, L. E. (2004) J. Am. Chem. Soc. 126, 3964-3973.
21. Fiaux, J., Bertelsen, E. B., Horwich, A. L. & Wuthrich, K. (2002) Nature 418, 207-211.
22. Pervushin, K., Riek, R., Wider, G. & Wuthrich, K. (1997) Proc. Natl. Acad. Sci. USA 94, 12366-12371.
23. Farrow, N. A., Zhang, O., Forman-Kay, J. D. & Kay, L. E. (1994) J. Biomol. t NMR 4, 727-734.
24. Montelione, G. T. & Wagner, G. (1989) J. Am. Chem. Soc. 111, 3096-3098.
25. Mulder, F. A., Mittermaier, A., Hon, B., Dahlquist, F. W. & Kay, L. E. (2001) Nat. Struct. Biol. 8, 932-935.
26. Weber-Ban, E. U., Reid, B. G., Miranker, A. D. & Horwich, A. L. (1999) Nature 401, 90-93.
27. Thompson, M. W. & Maurizi, M. R. (1994) J. Biol. Chem. 269, 18201-18208.
28. Singh, S. K., Guo, F. & Maurizi, M. R. (1999) Biochemistry 38, 14906-14915.
29. Kang, S. G., Maurizi, M. R., Thompson, M., Mueser, T. & Ahvazi, B. (2004) J. Struct. Biol. 148, 338-352.
30. Kim, D. Y. & Kim, K. K. (2003) J. Biol. Chem. 278, 50664-50670.