The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation

Journal of Biological Chemistry

Volumn 280, Issue 16, 2005, Pages 16185-16196

  Gribun, Anna ^a   Kimber, Matthew S ^b   Ching, Reagan ^a   Sprangers, Remco ^a   Fiebig, Klaus M ^b   Houry, Walid A ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b Affinium Pharmaceuticals   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; AMINO ACIDS; BIOCHEMISTRY; CHEMICAL BONDS; COMPLEXATION; DATA ACQUISITION; MICROORGANISMS; X RAY ANALYSIS;

ACTIVE SITES; BIOCHEMICAL DATA; MUTATION; RING INTERACTIONS;

ENZYME KINETICS;

ALANINE; ENDOPEPTIDASE CLP; ENDOPEPTIDASE CLPX; PROLINE; PROTEIN SUBUNIT;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOCHEMISTRY; COMPLEX FORMATION; DIMERIZATION; MOLECULAR INTERACTION; MUTATION; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; STREPTOCOCCUS PNEUMONIAE; STRUCTURE ANALYSIS; X RAY ANALYSIS;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; ENDOPEPTIDASE CLP; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SERINE ENDOPEPTIDASES; SPECTROPHOTOMETRY, ULTRAVIOLET; STREPTOCOCCUS PNEUMONIAE;

STREPTOCOCCUS PNEUMONIAE;

EID: 18144426344     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414124200     Document Type: Article

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