Effects of local protein stability and the geometric position of the substrate degradation tag on the efficiency of ClpXP denaturation and degradation

Journal of Structural Biology

Volumn 146, Issue 1-2, 2004, Pages 130-140

  Kenniston, Jon A ^a   Burton, Randall E ^a   Siddiqui, Samia M ^a   Baker, Tania A ^b   Sauer, Robert T ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CYSTEINE; PROTEASE CLPXP; PROTON; UNCLASSIFIED DRUG;

ANALYTIC METHOD; BACTERIAL STRAIN; BACTERIUM MUTANT; CARBOXY TERMINAL SEQUENCE; CHEMICAL BINDING; CONFERENCE PAPER; CORRELATION ANALYSIS; ENZYME DEGRADATION; ENZYME DENATURATION; ENZYME SUBSTRATE; ION EXCHANGE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; THERMODYNAMICS; THERMUS THERMOPHILUS; WILD TYPE;

ADENOSINE TRIPHOSPHATASES; ENDOPEPTIDASE CLP; ENZYME STABILITY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KINETICS; MOLECULAR PROBES; MUTAGENESIS, SITE-DIRECTED; PROTEIN DENATURATION; RIBONUCLEASE H, CALF THYMUS; THERMUS THERMOPHILUS;

EID: 1642308732     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsb.2003.10.023     Document Type: Conference Paper

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