Identification of pyrimethamine- and chloroquine-resistant Plasmodium falciparum in Africa between 1984 and 1998: Genotyping of archive blood samples

Malaria Journal

Volumn 10, Issue , 2011, Pages

  Saito Nakano, Yumiko ^a   Tanabe, Kazuyuki ^b   Mita, Toshihiro ^c  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Africa; Archive sample; Chloroquine; dhfr; Drug resistance; pfcrt; Plasmodium falciparum; Pyrimethamine

Indexed keywords

CHLOROQUINE; DIHYDROFOLATE REDUCTASE; PLASMODIUM FALCIPARUM CHLOROQUINE TRANSPORTER PROTEIN; PROTEIN; PYRIMETHAMINE; UNCLASSIFIED DRUG; ANTIMALARIAL AGENT; CARRIER PROTEIN; PFCRT PROTEIN, PLASMODIUM FALCIPARUM; PROTOZOAL DNA; PROTOZOAL PROTEIN;

AFRICA; ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; GENE MUTATION; GENE SEQUENCE; GENOTYPE; HUMAN; NONHUMAN; PARASITE IDENTIFICATION; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; BLOOD; DRUG EFFECT; DRUG RESISTANCE; DRUG SENSITIVITY; GENETICS; GENOTYPING TECHNIQUE; ISOLATION AND PURIFICATION; MALARIA FALCIPARUM; PARASITOLOGY; PATHOGENICITY;

AFRICA; ANTIMALARIALS; CHLOROQUINE; DNA, PROTOZOAN; DRUG RESISTANCE; GENOTYPE; GENOTYPING TECHNIQUES; HUMANS; MALARIA, FALCIPARUM; MEMBRANE TRANSPORT PROTEINS; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; PYRIMETHAMINE;

EID: 84855165190     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-10-388     Document Type: Article

References (41)

1. Chloroquine-resistant Plasmodium falciparum from East Africa: cultivation and drug sensitivity of the Tanzanian I/CDC strain from an American tourist. Campbell CC, Chin W, Collins WE, Teutsch SM, Moss DM, Lancet 1979 2 1151 1154 91887 (Pubitemid 10208358)
2. Chloroquine-resistant Plasmodium falciparum malaria in Kenya. Fogh S, Jepsen S, Effersoe P, Trans R Soc Trop Med Hyg 1979 73 228 229 10.1016/0035-9203(79)90220-7 382468 (Pubitemid 9159413)
3. Resistance of Plasmodium falciparum in Tanganyika to pyrimethamine administered at weekly intervals. Clyde DF, Shute GT, Trans R Soc Trop Med Hyg 1957 51 505 513 10.1016/0035-9203(57)90039-1 13496184
4. Following the path of most resistance: dhps K540E dispersal in African Plasmodium falciparum. Naidoo I, Roper C, Trends Parasitol 2010 26 447 456 10.1016/j.pt.2010.05.001 20728060
5. History, dynamics, and public health importance of malaria parasite resistance. Talisuna AO, Bloland P, D'Alessandro U, Clin Microbiol Rev 2004 17 235 254 10.1128/CMR.17.1.235-254.2004 14726463 (Pubitemid 38120936)
6. Evolution of resistance to sulfadoxine-pyrimethamine in Plasmodium falciparum. Gatton ML, Martin LB, Cheng Q, Antimicrob Agents Chemother 2004 48 2116 2123 10.1128/AAC.48.6.2116-2123.2004 15155209 (Pubitemid 38691607)
7. The anatomy of a malaria disaster: drug policy choice and mortality in African children. Hastings IM, Korenromp EL, Bloland PB, Lancet Infect Dis 2007 7 739 748 10.1016/S1473-3099(07)70214-1 17884732 (Pubitemid 47610756)
8. Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LM, Sidhu AB, Naude B, Deitsch KW, et al. Mol Cell 2000 6 861 871 10.1016/S1097-2765(05)00077-8 11090624
9. Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum. Cooper RA, Ferdig MT, Su XZ, Ursos LM, Mu J, Nomura T, Fujioka H, Fidock DA, Roepe PD, Wellems TE, Mol Pharmacol 2002 61 35 42 10.1124/mol.61.1.35 11752204 (Pubitemid 34049510)
10. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Peterson DS, Walliker D, Wellems TE, Proc Natl Acad Sci USA 1988 85 9114 9118 10.1073/pnas.85.23.9114 2904149 (Pubitemid 19001850)
11. Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase. Sirawaraporn W, Sathitkul T, Sirawaraporn R, Yuthavong Y, Santi DV, Proc Natl Acad Sci USA 1997 94 1124 1129 10.1073/pnas.94.4.1124 9037017 (Pubitemid 27087815)
12. Compensatory mutations restore fitness during the evolution of dihydrofolate reductase. Brown KM, Costanzo MS, Xu W, Roy S, Lozovsky ER, Hartl DL, Mol Biol Evol 2010 27 2682 2690 10.1093/molbev/msq160 20576759
13. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL, Proc Natl Acad Sci USA 2009 106 12025 12030 10.1073/pnas.0905922106 19587242
14. Indigenous evolution of Plasmodium falciparum pyrimethamine resistance multiple times in Africa. Mita T, Tanabe K, Takahashi N, Culleton R, Ndounga M, Dzodzomenyo M, Akhwale WS, Kaneko A, Kobayakawa T, J Antimicrob Chemother 2009 63 252 255 19036751
15. Sequence polymorphisms in pfcrt are strongly associated with chloroquine resistance in Plasmodium falciparum. Chen N, Russell B, Staley J, Kotecka B, Nasveld P, Cheng Q, J Infect Dis 2001 183 1543 1545 11319698 (Pubitemid 32417711)
16. The impact of malaria parasitism: from corpuscles to communities. Wellems TE, Hayton K, Fairhurst RM, Journal Clinical Investigation 2009 119 2496 2505 10.1172/JCI38307
17. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Wootton JC, Feng X, Ferdig MT, Cooper RA, Mu J, Baruch DI, Magill AJ, Su XZ, Nature 2002 418 320 323 10.1038/nature00813 12124623 (Pubitemid 34790681)
18. A shared Asian origin of the triple-mutant dhfr allele in Plasmodium falciparum from sites across Africa. Maiga O, Djimde AA, Hubert V, Renard E, Aubouy A, Kironde F, Nsimba B, Koram K, Doumbo OK, Le Bras J, Clain J, J Infect Dis 2007 196 165 172 10.1086/518512 17538897 (Pubitemid 46982751)
19. Intercontinental spread of pyrimethamine-resistant malaria. Roper C, Pearce R, Nair S, Sharp B, Nosten F, Anderson T, Science 2004 305 1124 10.1126/science.1098876 15326348 (Pubitemid 39100317)
20. Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Cowman AF, Morry MJ, Biggs BA, Cross GA, Foote SJ, Proc Natl Acad Sci USA 1988 85 9109 9113 10.1073/pnas.85.23.9109 3057499 (Pubitemid 19001849)
21. High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance Gene pfmdr1. Babiker HA, Pringle SJ, Abdel-Muhsin A, Mackinnon M, Hunt P, Walliker D, J Infect Dis 2001 183 1535 1538 10.1086/320195 11319692 (Pubitemid 32417707)
22. Characteristics of Plasmodium falciparum dhfr haplotypes that confer pyrimethamine resistance, Kilifi, Kenya, 1987-2006. Certain LK, Briceno M, Kiara SM, Nzila AM, Watkins WM, Sibley CH, J Infect Dis 2008 197 1743 1751 10.1086/588198 18513156 (Pubitemid 351919640)
23. Genetic evidence for Plasmodium falciparum resistance to chloroquine and pyrimethamine in Indochina and the Western Pacific between 1984 and 1998. Saito-Nakano Y, Tanabe K, Kamei K, Iwagami M, Komaki-Yasuda K, Kawazu S, Kano S, Ohmae H, Endo T, Am J Trop Med Hyg 2008 79 613 619 18840753
24. Giemsa-stained thick blood films as a source of DNA for Plasmodium species-specific real-time PCR. Cnops L, Van Esbroeck M, Bottieau E, Jacobs J, Malar J 2010 9 370 10.1186/1475-2875-9-370 21176207
25. Leishmania identification by PCR of Giemsa-stained lesion imprint slides stored for up to 36 years. Volpini AC, Marques MJ, Lopes dos Santos S, Machado-Coelho GL, Mayrink W, Romanha AJ, Clin Microbiol Infect 2006 12 815 818 16842583
26. Spread and evolution of Plasmodium falciparum drug resistance. Mita T, Tanabe K, Kita K, Parasitol Int 2009 58 201 209 10.1016/j.parint.2009.04.004 19393762
27. Mutagenesis of dihydrofolate reductase from Plasmodium falciparum: analysis in Saccharomyces cerevisiae of triple mutant alleles resistant to pyrimethamine or WR99210. Ferlan JT, Mookherjee S, Okezie IN, Fulgence L, Sibley CH, Mol Biochem Parasitol 2001 113 139 150 10.1016/S0166-6851(01)00207-9 11254962 (Pubitemid 32209290)
28. Common origin and fixation of Plasmodium falciparum dhfr and dhps mutations associated with sulfadoxine-pyrimethamine resistance in a low-transmission area in South America. McCollum AM, Mueller K, Villegas L, Udhayakumar V, Escalante AA, Antimicrob Agents Chemother 2007 51 2085 2091 10.1128/AAC.01228-06 17283199 (Pubitemid 46903098)
29. Hitchhiking and selective sweeps of Plasmodium falciparum sulfadoxine and pyrimethamine resistance alleles in a population from central Africa. McCollum AM, Basco LK, Tahar R, Udhayakumar V, Escalante AA, Antimicrob Agents Chemother 2008 52 4089 4097 10.1128/AAC.00623-08 18765692
30. Antifolate resistance in Plasmodium falciparum: multiple origins and identification of novel dhfr alleles. McCollum AM, Poe AC, Hamel M, Huber C, Zhou Z, Shi YP, Ouma P, Vulule J, Bloland P, Slutsker L, et al. J Infect Dis 2006 194 189 197 10.1086/504687 16779725 (Pubitemid 44087190)
31. Mutations associated with sulfadoxine-pyrimethamine and chlorproguanil resistance in Plasmodium falciparum isolates from Blantyre, Malawi. Alker AP, Mwapasa V, Purfield A, Rogerson SJ, Molyneux ME, Kamwendo DD, Tadesse E, Chaluluka E, Meshnick SR, Antimicrob Agents Chemother 2005 49 3919 3921 10.1128/AAC.49.9.3919-3921.2005 16127071 (Pubitemid 41233050)
32. Highly pyrimethamine-resistant alleles of dihydrofolate reductase in isolates of Plasmodium falciparum from Tanzania. Hastings MD, Bates SJ, Blackstone EA, Monks SM, Mutabingwa TK, Sibley CH, Trans R Soc Trop Med Hyg 2002 96 674 676 10.1016/S0035-9203(02)90349-4 12630380 (Pubitemid 36231495)
33. Antifolate resistance in Africa and the 164-dollar question. Hyde JE, Trans R Soc Trop Med Hyg 2008 102 301 303 10.1016/j.trstmh.2008.01.003 18316104
34. Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance. Foote SJ, Galatis D, Cowman AF, Proc Natl Acad Sci USA 1990 87 3014 3017 10.1073/pnas.87.8.3014 2183221
35. Artesunate-dapsone-proguanil treatment of falciparum malaria: genotypic determinants of therapeutic response. Krudsood S, Imwong M, Wilairatana P, Pukrittayakamee S, Nonprasert A, Snounou G, White NJ, Looareesuwan S, Trans R Soc Trop Med Hyg 2005 99 142 149 10.1016/j.trstmh.2004.07.001 15607340 (Pubitemid 40028795)
36. Chloroquine resistant P. falciparum prevalence is low and unchanged between 1990 and 2005 in Guinea-Bissau: an effect of high chloroquine dosage? Ursing J, Schmidt BA, Lebbad M, Kofoed PE, Dias F, Gil JP, Rombo L, Infect Genet Evol 2007 7 555 561 10.1016/j.meegid.2007.03.006 17467343 (Pubitemid 47342374)
37. Decreased sensitivity to chloroquine and quinine of some Plasmodium falciparum strains from Senegal in September 1984. Brandicourt O, Druilhe P, Diouf F, Brasseur P, Turk P, Danis M, Am J Trop Med Hyg 1986 35 717 721 3524287 (Pubitemid 16072232)
38. Single-dose chloroquine therapy for Plasmodium falciparum in children in Togo, West Africa. Breman JG, Gayibor A, Roberts JM, Sexton JD, Agbo K, Miller KD, Karsa T, Murphy K, Am J Trop Med Hyg 1987 36 469 473 3555135 (Pubitemid 17099456)
39. Chloroquine-resistant Plasmodium falciparum in Mali revealed by congenital malaria. Chabasse D, De Gentile L, Ligny C, Le Bras J, Rialland X, Bouchara JP, Trans R Soc Trop Med Hyg 1988 82 547 10.1016/0035-9203(88)90499-3 3076710
40. History and current status of Plasmodium falciparum antimalarial drug resistance in Madagascar. Andriantsoanirina V, Menard D, Tuseo L, Durand R, Scand J Infect Dis 2010 42 22 32 10.3109/00365540903289670 19883158
41. Origins of the recent emergence of Plasmodium falciparum pyrimethamine resistance alleles in Madagascar. Andriantsoanirina V, Bouchier C, Tichit M, Jahevitra M, Rabearimanana S, Randrianjafy R, Ratsimbasoa A, Mercereau-Puijalon O, Durand R, Menard D, Antimicrob Agents Chemother 2010 54 2323 2329 10.1128/AAC.01511-09 20308388