Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages

Free Radical Biology and Medicine

Volumn 52, Issue 1, 2012, Pages 182-190

  Shoeb, Mohammad ^a   Ramana, Kota V ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Arachidonic acid; COX; Inflammation; LOX; Vitamin B1

Indexed keywords

ARACHIDONIC ACID; BACTERIUM LIPOPOLYSACCHARIDE; BENFOTIAMINE; CYCLOOXYGENASE 2; EARLY GROWTH RESPONSE FACTOR 1; ENDOTOXIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKOTRIENE DERIVATIVE; LIPOXYGENASE; LIPOXYGENASE 5; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE A2; PROSTACYCLIN; PROSTACYCLIN SYNTHASE; PROSTAGLANDIN E2; SYNAPTOTAGMIN I; THROMBOXANE A2; THROMBOXANE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARACHIDONIC ACID METABOLISM; ARTICLE; CELL ADHESION; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; INFLAMMATION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARACHIDONIC ACID; CELL ADHESION; CELL DEATH; CELL LINE; CYCLOOXYGENASE 2; DINOPROSTONE; EPOPROSTENOL; EXTRACELLULAR MATRIX PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; INFLAMMATION; LEUKOTRIENES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; PROTEIN-LYSINE 6-OXIDASE; SIGNAL TRANSDUCTION; THIAMINE; THROMBOXANE B2;

BACTERIA (MICROORGANISMS); MURINAE;

EID: 84655167299     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.10.444     Document Type: Article

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