Is prostacyclin responsible for producing the hyperdynamic response during early sepsis?

Critical Care Medicine

Volumn 28, Issue 5, 2000, Pages 1534-1539

  Wang, Ping ^a,b   Zhou, Mian ^a   Cioffi, William G ^a   Bland, Kirby I ^a   Ba, Zheng F ^a   Chaudry, Irshad H ^a  

^a BROWN UNIVERSITY   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

Author keywords

Cecal ligation and puncture; Heart performance; Microcirculation; Prostacyclin synthase; Tranylcypromine

Indexed keywords

PROSTACYCLIN; PROSTACYCLIN SYNTHASE; TRANYLCYPROMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTOXEMIA; ENZYME INHIBITION; HEART LEFT VENTRICLE PRESSURE; HEART PERFORMANCE; LASER DOPPLER FLOWMETRY; LIGATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUNCTURE; RADIOIMMUNOASSAY; RAT; SEPSIS;

EID: 0034072363     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200005000-00046     Document Type: Article

References (44)

1. 1. Baue AE, Durham R, Faist E: Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): Are we winning the battle? Shock 1998; 10:79-89
2. 2. Vincent JL, de Mendonca A, Cantraine F, et al: Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study. Crit Care Med 1998; 26: 1793-1800
3. 3. Dellinger RP, Opal SM, Rotrosen D, et al: From the bench to the bedside: The future of sepsis research. Chest 1997; 111:744-753
4. 4. Deitch EA: Animal models of sepsis and shock: A review and lessons learned. Shock 1998; 9:1-11
5. 5. Wang P, Chaudry IH: Mechanism of hepato-cellular dysfunction during hyperdynamic sepsis. Am J Physiol 1996; 270:R927-R938
6. 6. Mangino MJ, Mangino JE, Murphy MK, et al: Arachidonic acid metabolism in intestinal hypothermic preservation injury. Cryobiology 1996; 33:404-412
7. 7. Kimblad PO, Green K, Sjoberg T, et al: Prostanoid release after lung transplantation. J Heart Lung Transplant 1996; 15:999-1004
8. 8. Myers SI, Hernandez R, Horton J: Endotoxic shock has different effects on renal and splanchnic eicosanoid synthesis. Prostaglandins Leukot Essent Fatty Acids 1993; 49:509-513
9. 9. Morris DD, Moore JN: Endotoxin-induced production of thromboxane and prostacyclin by equine peritoneal macrophages. Circ Shock 1987; 23:295-303
10. 10. Meyrick B, Berry LC, Jr, Christman BW: Response of cultured human pulmonary artery endothelial cells to endotoxin. Am J Physiol 1995; 268:L239-L244
11. 2 with sepsis. Res Com Mol Pathol Pharmacol 1994; 86:37-42
12. 2 formation is increased in human sepsis syndrome: Effects of cyclooxygenase inhibition. Am Rev Respir Dis 1991; 144:1095-1101
13. 13. Camporesi EM, Oda S, Fracica PJ, et al: Eicosanoids and the hemodynamic course of live Escherichia coli-induced sepsis in baboons. Circ Shock 1989; 29:229-244
14. 14. Chaudry IH, Wichterman KA, Baue AE: Effect of sepsis on tissue adenine nucleotide levels. Surgery 1979; 85:205-211
15. 15. Wang P, Chaudry IH: A single hit model of polymicrobial sepsis: Cecal ligation and puncture. Sepsis 1998; 2:225-231
16. 16. Okatani Y, Watanabe K, Nakano Y, et al: Relaxant effect of nitric oxide and prostacyclin on serotonin-induced vasocontraction of human umbilical artery. Acta Obstet Gynecol Scand 1996; 75:108-112
17. 17. Wang P, Ba ZF, Chaudry IH: Pentoxifylline maintains hepatocellular function and improves cardiac performance during early sepsis. J Trauma 1997; 42:429-436
18. 18. Wang P, Zhou M, Rana MW, et al: Differential alterations in microvascular perfusion in various organs during early and late sepsis. Am J Physiol 1992; 263:G38-G43
19. 19. Wang P, Ba ZF, Ayala A, et al: Hepatocellular dysfunction persists during early sepsis despite increased volume of crystalloid resuscitation. J Trauma 1992; 32:389-397
20. 20. Fink MP, Morrissey PE, Stein KL, et al: Systemic and regional hemodynamic effects of cyclooxygenase and thromboxane synthetase inhibition in normal and hyperdynamic endotoxemic rabbits. Circ Shock 1988; 26: 41-57
21. 2 increase in rats with peritonitis due to cecal ligation. Circ Shock 1985; 16:297-305
22. 22. Wang P, Ba ZF, Chaudry IH: Hepatocellular dysfunction occurs earlier than the onset of hyperdynamic circulation during sepsis. Shock 1995; 3:21-26
23. 23. Hong SL, Carty T, Deykin D: Tranylcypromine and 15-hydroperoxyarachidonate affect arachidonic acid release in addition to inhibition of prostacyclin synthesis in calf aortic endothelial cells. J Biol Chem 1980; 255: 9538-9540
24. 24. Thase ME, Trivedi MH, Rush AJ: MAOIs in the contemporary treatment of depression. Neuropsychopharmacology 1995; 12: 185-219
25. 25. Shah MA, Trackman PC, Gallop PM, et al: Reaction of lysyl oxidase with trans-2-phenylcyclopropylamine. J Biol Chem 1993; 268:11580-11585
26. 26. Sayre LM, Naismith RT II, Bada MA, et al: Trans-2-phenylcyclopropyiamine is a substrate for and inactivator of horseradish peroxidase. Biochim Biophys Acta 1996; 1296: 250-256
27. 27. Hahn PY, Wang P, Tait SM, et al: Sustained elevation in circulating catecholamine levels during polymicrobial sepsis. Shock 1995; 4:269-273
28. 28. Wang P, Ba ZF, Chaudry IH: Hepatic extraction of indocyanine green is depressed early in sepsis despite increased hepatic blood flow and cardiac output. Arch Surg 1991; 126: 219-224
29. 29. Geraci M, Shepherd D, Moore M, et al: Cloning and regulation of gene expression in the lung. Chest 1997; 111:129S
30. 30. Sasaki Y, Takahashi T, Tanaka I, et al: Expression of prostacyclin receptor in human megakaryocytes. Blood 1997; 90:1039-1046
31. 31. Fink MP, MacVittie TJ, Casey LC: Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis. Ann Surg 1984; 200:619-626
32. 32. Bernard GR, Wheeler AP, Russell JA, et al: The effects of ibuprofen on the physiology and survival of patients with sepsis. N Engl J Med 1997; 336:912-918
33. 33. Scheeren T, Susanto F, Reinauer H, et al: Prostacyclin improves glucose utilization in patients with sepsis. J Crit Care 1994; 9:175-184
34. 34. DeBacker D, Berre J, Zhang H, et al: Relationship between oxygen uptake and oxygen delivery in septic patients: Effects of prostacyclin versus dobutamine. Crit Care Med 1993; 21:1658-1664
35. 35. Woditsch I, Schror K: Prostacyclin rather than endogenous nitric oxide is a tissue protective factor in myocardial ischemia. Am J Physiol 1992; 263:H1390-H1396
36. 36. Wang P, Ba ZF, Chaudry IH: Increase in hepatic blood flow during early sepsis is due to increased portal blood flow. Am J Physiol 1991; 261:R1507-R1512
37. 37. Wichterman KA, Baue AE, Chaudry IH: Sepsis and septic shock: A review of laboratory models and a proposal. J Surg Res 1980; 29:189-201
38. 38. Fink MP, Heard SO: Laboratory models of sepsis and septic shock. J Surg Res 1990; 49:186-196
39. 39. Doig GS, Martin CM, Sibbald WJ: Polymyxindextran antiendotoxin pretreatment in an ovine model of normotensive sepsis. Crit Care Med 1997; 25:1956-1961
40. 40. Wu LL, Tang C, Liu MS: Hyper-and hypocardiodynamic states are associated with externalization and internalization, respectively, of α-adrenergic receptors in rat heart during sepsis. Shock 1997; 7:318-323
41. 41. Vromen A, Arkovitz MS, Zingarelli B, et al: Low-level expression and limited role for the inducible isoform of nitric oxide synthase in the vascular hyporeactivity and mortality associated with cecal ligation and puncture in the rat. Shock 1996; 6:248-253
42. 42. Wang P, Zhou M, Ba ZF, et al: Up-regulation of a novel potent vasodilatory peptide adrenomedullin during polymicrobial sepsis. Shock 1998; 10:118-122
43. 43. Wang P, Ba ZF, Cioffi WG, et al: The pivotal role of adrenomedullin in producing hyperdynamic circulation during the early stage of sepsis. Arch Surg 1998; 133:1298-1304
44. 44. Wang P, Ba ZF, Cioffi WG, et al: Factors responsible for producing the transition from the hyperdynamic to hypodynamic stage of sepsis: Role of a novel vasodilatory peptide, adrenomedullin. Surg Forum 1997; 48:122-124