Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN

Molecular and Cellular Biology

Volumn 23, Issue 19, 2003, Pages 6780-6789

  Katschinski, Dörthe M ^a   Marti, Hugo H ^d   Wagner, Klaus F ^b   Shibata, Junpei ^b   Eckhardt, Katrin ^c   Martin, Falk ^c   Depping, Reinhard ^b   Paasch, Uwe ^c   Gassmann, Max ^d   Ledermann, Birgit ^d   Desbaillets, Isabelle ^d,e   Wenger, Roland H ^c  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; GLYCOGEN; PASKIN; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN FIXL; PROTEIN SDS22; PROTEIN SERINE THREONINE KINASE; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL GROWTH; CELL MATURATION; CELL TYPE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STRUCTURES; ENZYME ACTIVITY; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETIC CODE; GENETIC RECOMBINATION; GERM CELL; GLYCOGEN SYNTHESIS; GLYCOLYSIS; IN VIVO STUDY; KNOCKOUT GENE; LACZ GENE; MALE; MEIOSIS; MOUSE; NONHUMAN; ORTHOLOGY; PASKIN GENE; PPP1R7 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TARGETING; REPORTER GENE; REPRODUCTION; SACCHAROMYCES CEREVISIAE; SPERMATOGENESIS; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; SPERM MOTILITY; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

ANIMALIA; MAMMALIA; RHIZOBIUM; RODENTIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0141781113     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.19.6780-6789.2003     Document Type: Article

References (29)

1. Amezcua, C. A., S. M. Harper, J. Rutter, and K. H. Gardner. 2002. Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation. Structure 10:1349-1361.
2. Bollen, M. 2001. Combinatorial control of protein phosphatase-1. Trends Biochem. Sci. 26:426-431.
3. Ceulemans, H., A. Van Eynde, E. Perez-Callejón, M. Beullens, W. Stalmans, and M. Bollen. 1999. Structure and splice products of the human gene encoding sds22, a putative mitotic regulator of protein phosphatase-1. Eur. J. Biochem. 262:36-42.
4. Ceulemans, H., V. Vulsteke, M. De Maeyer, K. Tatchell, W. Stalmans, and M. Bollen. 2002. Binding of the concave surface of the Sds22 superhelix to the α4/α5/α6-triangle of protein phosphatase-1. J. Biol. Chem. 277:47331-47337.
5. Chun, Y. S., J. W. Park, G. T. Kim, H. Shima, M. Nagao, M. S. Kim, and M. H. Chung. 2000. A sds22 homolog that is associated with the testis-specific serine/threonine protein phosphatase 1γ2 in rat testis. Biochem. Biophys. Res. Commun. 273:972-976.
6. Deng, C. X., A. Wynshaw-Boris, M. M. Shen, C. Daugherty, D. M. Ornitz, and P. Leder. 1994. Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev. 8:3045-3057.
7. Dioum, E. M., J. Rutter, J. R. Tuckerman, G. Gonzalez, M. A. Gilles-Gonzalez, and S. L. McKnight. 2002. NPAS2: a gas-responsive transcription factor. Science 298:2385-2387.
8. Gilles-Gonzalez, M. A., G. S. Ditta, and D. R. Helinski. 1991. A haemoprotein with kinase activity encoded by the oxygen sensor of Rhizobium meliloti. Nature 350:170-172.
9. Gu, Y. Z., J. B. Hogenesch, and C. A. Bradfield. 2000. The PAS superfamily: sensors of environmental and developmental signals. Annu. Rev. Pharmacol. Toxicol. 40:519-561.
10. Hofer, T., P. Spielmann, P. Stengel, B. Stier, D. M. Katschinski, I. Desbaillets, M. Gassmann, and R. H. Wenger. 2001. Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors. Biochem. Biophys. Res. Commun. 288:757-764.
11. Huang, Z., B. Khatra, M. Bollen, D. W. Carr, and S. Vijayaraghavan. 2002. Sperm PP1γ2 is regulated by a homologue of the yeast protein phosphatase binding protein sds22. Biol. Reprod. 67:1936-1942.
12. Katschinski, D. M., L. Le, D. Heinrich, K. F. Wagner, T. Hofer, S. G. Schindler, and R. H. Wenger. 2002. Heat induction of the unphosphorylated form of hypoxia-inducible factor-1α is dependent on heat shock protein-90 activity. J. Biol. Chem. 277:9262-9267.
13. Marti, H. H., D. M. Katschinski, K. F. Wagner, L. Schäffer, B. Stier, and R. H. Wenger. 2002. Isoform-specific expression of hypoxia-inducible factor-1α during the late stages of mouse spermiogenesis. Mol. Endocrinol. 16:234-243.
14. Max, B. 1992. This and that: hair pigments, the hypoxic basis of life and the Virgilian journey of the spermatozoon. Trends Pharmacol. Sci. 13:272-276.
15. Morais Cabral, J. H., A. Lee, S. L. Cohen, B. T. Chait, M. Li, and R. Mackinnon. 1998. Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain. Cell 95:649-655.
16. Mountford, P., B. Zevnik, A. Duwel, J. Nichols, M. Li, C. Dani, M. Robertson, I. Chambers, and A. Smith. 1994. Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc. Natl. Acad. Sci. USA 91:4303-4307.
17. Nebel, B. R., A. P. Amarose, and E. M. Hackett. 1961. Calendar of gametogenic development in the prepuberal male mouse. Science 134:832-833.
18. Ponting, C. P., and L. Aravind. 1997. PAS: a multifunctional domain family comes to light. Curr. Biol. 7:R674-R677.
19. Reppert, S. M., and D. R. Weaver. 2002. Coordination of circadian timing in mammals. Nature 418:935-941.
20. Rolfs, A., I. Kvietikova, M. Gassmann, and R. H. Wenger. 1997. Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J. Biol. Chem. 272:20055-20062.
21. Russell, L. D., R. A. Ettlin, A. P. Sinha Hikim, and E. D. Clegg. 1990. Histological and histopathological evaluation of the testis. Cache River Press, Clearwater, Fla.
22. Rutter, J., C. H. Michnoff, S. M. Harper, K. H. Gardner, and S. L. McKnight. 2001. PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase. Proc. Natl. Acad. Sci. USA 98:8991-8996.
23. Rutter, J., B. L. Probst, and S. L. McKnight. 2002. Coordinate regulation of sugar flux and translation by PAS kinase. Cell 111:17-28.
24. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
25. Schmidt, J. V., and C. A. Bradfield. 1996. Ah receptor signaling pathways. Annu. Rev. Cell Dev. Biol. 12:55-89.
26. Taylor, B. L., and I. B. Zhulin. 1999. PAS domains: internal sensors of oxygen, redox potential, and light. Microbiol. Mol. Biol. Rev. 63:479-506.
27. Tran, H. T., D. Bridges, A. Ulke, and G. B. Moorhead. 2002. Detection of multiple splice variants of the nuclear protein phosphatase 1 regulator sds22 in rat liver nuclei. Biochem. Cell Biol. 80:811-815.
28. 2-regulated gene expression. FASEB J. 16:1151-1162.
29. Zhulin, I. B., and B. L. Taylor. 1997. PAS domain S-boxes in archaea, bacteria and sensors for oxygen and redox. Trends Biochem. Sci. 22:331-333.