Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN

FEBS Journal

Volumn 278, Issue 10, 2011, Pages 1757-1768

  Schläfli, Philipp ^a   Tröger, Juliane ^a   Eckhardt, Katrin ^a   Borter, Emanuela ^a   Spielmann, Patrick ^a   Wenger, Roland H ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

metabolism; phospholipid; protein translation; ribosomal protein S6; sensory kinase

Indexed keywords

ELONGATION FACTOR; ELONGATION FACTOR 1A1; GLYCEROPHOSPHOLIPID; PER ARNT SIM DOMAIN SERINE THREONINE KINASE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL MONOPHOSPHATE; PHOSPHOLIPID; PROTEIN S6; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; FIBROBLAST; INHIBITION KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN MICROARRAY; PROTEIN TARGETING; TRANSLATION REGULATION;

EUKARYOTA; MAMMALIA;

EID: 79955611332     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08100.x     Document Type: Article

References (33)

1. Ponting CP, &, Aravind L, (1997) PAS: a multifunctional domain family comes to light. Curr Biol 7, R674-R677.
2. Lowrey PL, &, Takahashi JS, (2000) Genetics of the mammalian circadian system: photic entrainment, circadian pacemaker mechanisms, and posttranslational regulation. Annu Rev Genet 34, 533-562. (Pubitemid 32065932)
3. Mimura J, &, Fujii-Kuriyama Y, (2003) Functional role of AhR in the expression of toxic effects by TCDD. Biochim Biophys Acta 1619, 263-268. (Pubitemid 36160604)
4. 2-regulated gene expression. FASEB J 16, 1151-1162. (Pubitemid 34815403)
5. Hofer T, Spielmann P, Stengel P, Stier B, Katschinski DM, Desbaillets I, Gassmann M, &, Wenger RH, (2001) Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors. Biochem Biophys Res Commun 288, 757-764. (Pubitemid 33140946)
6. Rutter J, Michnoff CH, Harper SM, Gardner KH, &, McKnight SL, (2001) PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase. Proc Natl Acad Sci USA 98, 8991-8996. (Pubitemid 32743857)
7. Amezcua CA, Harper SM, Rutter J, &, Gardner KH, (2002) Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation. Structure 10, 1349-1361. (Pubitemid 35232384)
8. Rutter J, Probst BL, &, McKnight SL, (2002) Coordinate regulation of sugar flux and translation by PAS kinase. Cell 111, 17-28.
9. Smith TL, &, Rutter J, (2007) Regulation of glucose partitioning by PAS kinase and Ugp1 phosphorylation. Mol Cell 26, 491-499. (Pubitemid 46765181)
10. Grose JH, Smith TL, Sabic H, &, Rutter J, (2007) Yeast PAS kinase coordinates glucose partitioning in response to metabolic and cell integrity signaling. EMBO J 26, 4824-4830. (Pubitemid 350191309)
11. Wilson WA, Skurat AV, Probst B, de Paoli-Roach A, Roach PJ, &, Rutter J, (2005) Control of mammalian glycogen synthase by PAS kinase. Proc Natl Acad Sci USA 102, 16596-16601. (Pubitemid 41688822)
12. da Silva Xavier G, Rutter J, &, Rutter GA, (2004) Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose. Proc Natl Acad Sci USA 101, 8319-8324. (Pubitemid 38736573)
13. An R, da Silva Xavier G, Hao HX, Semplici F, Rutter J, &, Rutter GA, (2006) Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic beta-cells. Biochem Soc Trans 34, 791-793. (Pubitemid 44796422)
14. Katschinski DM, Marti HH, Wagner KF, Shibata J, Eckhardt K, Martin F, Depping R, Paasch U, Gassmann M, Ledermann B, et al. (2003) Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN. Mol Cell Biol 23, 6780-6789. (Pubitemid 37214649)
15. Borter E, Niessen M, Zuellig R, Spinas GA, Spielmann P, Camenisch G, &, Wenger RH, (2007) Glucose-stimulated insulin production in mice deficient for the PAS kinase PASKIN. Diabetes 56, 113-117.
16. Hao HX, Cardon CM, Swiatek W, Cooksey RC, Smith TL, Wilde J, Boudina S, Abel ED, McClain DA, &, Rutter J, (2007) PAS kinase is required for normal cellular energy balance. Proc Natl Acad Sci USA 104, 15466-15471. (Pubitemid 47502940)
17. Schläfli P, Borter E, Spielmann P, &, Wenger RH, (2009) The PAS-domain kinase PASKIN: a new sensor in energy homeostasis. Cell Mol Life Sci 66, 876-883.
18. Eckhardt K, Tröger J, Reissmann J, Katschinski DM, Wagner KF, Stengel P, Paasch U, Hunziker P, Borter E, Barth S, et al. (2007) Male germ cell expression of the PAS domain kinase PASKIN and its novel target eukaryotic translation elongation factor eEF1A1. Cell Physiol Biochem 20, 227-240. (Pubitemid 46956826)
19. Kikani CK, Antonysamy SA, Bonanno JB, Romero R, Zhang FF, Russell M, Gheyi T, Iizuka M, Emtage S, Sauder JM, et al. (2010) Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation. J Biol Chem 285, 41034-41043.
20. Ferrari S, Bandi HR, Hofsteenge J, Bussian BM, &, Thomas G, (1991) Mitogen-activated 70K S6 kinase. Identification of in vitro 40 S ribosomal S6 phosphorylation sites. J Biol Chem 266, 22770-22775.
21. Pende M, Um SH, Mieulet V, Sticker M, Goss VL, Mestan J, Mueller M, Fumagalli S, Kozma SC, &, Thomas G, (2004) S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5â-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol Cell Biol 24, 3112-3124. (Pubitemid 38452057)
22. Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, Sonenberg N, &, Blenis J, (2007) RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J Biol Chem 282, 14056-14064. (Pubitemid 47100467)
23. Kielbassa K, Müller HJ, Meyer HE, Marks F, &, Gschwendt M, (1995) Protein kinase CÎ-specific phosphorylation of the elongation factor eEF-α and an eEF-1α peptide at threonine 431. J Biol Chem 270, 6156-6162.
24. Bell RM, &, Burns DJ, (1991) Lipid activation of protein kinase C. J Biol Chem 266, 4661-4664. (Pubitemid 21909407)
25. Krieg J, Hofsteenge J, &, Thomas G, (1988) Identification of the 40 S ribosomal protein S6 phosphorylation sites induced by cycloheximide. J Biol Chem 263, 11473-11477.
26. Meyuhas O, (2000) Synthesis of the translational apparatus is regulated at the translational level. Eur J Biochem 267, 6321-6330.
27. Ruvinsky I, Sharon N, Lerer T, Cohen H, Stolovich-Rain M, Nir T, Dor Y, Zisman P, &, Meyuhas O, (2005) Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis. Genes Dev 19, 2199-2211. (Pubitemid 41330321)
28. Meyuhas O, (2008) Physiological roles of ribosomal protein S6: one of its kind. Int Rev Cell Mol Biol 268, 1-37.
29. Lemmon MA, (2008) Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol 9, 99-111. (Pubitemid 351158910)
30. Ceccarelli DF, Blasutig IM, Goudreault M, Li Z, Ruston J, Pawson T, &, Sicheri F, (2007) Non-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9. J Biol Chem 282, 13864-13874. (Pubitemid 47100518)
31. Di Paolo G, &, De Camilli P, (2006) Phosphoinositides in cell regulation and membrane dynamics. Nature 443, 651-657. (Pubitemid 44564702)
32. Barth S, Nesper J, Hasgall PA, Wirthner R, Nytko KJ, Edlich F, Katschinski DM, Stiehl DP, Wenger RH, &, Camenisch G, (2007) The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability. Mol Cell Biol 27, 3758-3768. (Pubitemid 46726183)
33. Ghosh S, Strum JC, Sciorra VA, Daniel L, &, Bell RM, (1996) Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells. J Biol Chem 271, 8472-8480.